101 results about "Arterial blood flow" patented technology

Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

A method and apparatus for non-invasively evaluating endothelial activity in a patient, particularly for indicating the presence of an endothelial dysfunction condition, by applying an occluding pressure to a predetermined part of an arm or leg of the patient to occlude arterial blood flow therein; maintaining the occluding pressure for a predetermined time period; removing the occluding pressure after the elapse of the predetermined time period to restore arterial blood flow; monitoring a digit of the arm or leg by a digit-probe for changes in the peripheral arterial tone therein before and after the application of the occluding pressure to the arm or leg of the patient; and utilizing any detected changes in the peripheral arterial tone for evaluating endothelial activity in the patient. Particularly important advantages are provided when the occluding cuff is applied to the digit of the patient receiving the monitoring digit-probe, on the proximal side thereof with respect to the patient's heart, and also when a reference digit-probe is applied to another digit, not influenced by the occluding pressure, to compensate for shifts inherent to vascular beds.

Disclosed herein are exemplary embodiments of an impulse therapy garment for use in pump therapy for enhancing venous and arterial blood flow. The garment may be advantageously fitted to a human foot, and may include a rotationally positionable heel-strap, an air inlet connector, separate dorsum straps, or other features. For example, other garments may include a washer having a center hole locatable around the stem and configured to be forcibly retained against the outer surface of the fabric by snap-fit using annular stem protrusions extending from an external surface of the stem. In further embodiments, a garment may include a bladder retention fastener configured to retain an end of the bladder to the fabric to allow substantially differential movement between the fabric and non-retained portions of the bladder during inflation and deflation of the bladder.

The invention discloses a dynamic driving environment human physiological characteristics and biomechanics test platform which mainly consists of a dynamic excitation system, a three-dimensional digital adjustable seat system, a three-dimensional adjustable driving mechanism and a human physiological characteristics and biomechanics test system. The invention can simulate the dynamic environment (vibration environment) of automobiles, which means to implement the stepless frequency conversion, the amplitude, the frequency fixation and frequency sweep vibration for the variable acceleration; simulate the posture operation of the automobiles in various driving environment; measure the human physiological character indexes of the human electromyography signals, the human arterial blood flow, the human blood pressure response, the human heartbeat number of a driver, etc., and the vibration response of every human part, the contact stress of a human-chair interface and the body pressure distribution of human buttock and back; study and comprehensively test the human physiological characteristics and the human biomechanics of the driving postures of different populations. Through the stimulation on a dynamic driving environment human physiological characteristics and biomechanics test system, scientific data required by the automobile human-machine interface design for populations with different shapes can be obtained.

Method and apparatus to non-invasively measure fetal blood oxygen saturation levels. Optical sensors capable of producing and detecting multiple wavelengths of tissue penetrating light are placed on the surface of the maternal abdomen, and the light beams directed to pass through at least a portion of the uterus containing the fetus. The fetal heart rate is monitored by Doppler ultrasound, and pure maternal optical signal related to maternal arterial blood flow are also measured. The optical sensors collect composite signals containing both maternal and fetal hemoglobin absorption spectral data and modulated by their respective pulsatile blood flows. The composite signals processed in the time domain and frequency domain, the pure maternal pulsatile optical signal used to extract the maternal contribution to the composite signal, and the fetal pulsatile signal is used to lock onto and extract the fetal contribution to the composite signal, and a fetal blood oxygen level deduced.

A heart-rate sensor for detecting artery blood-flow volume per unit length change in a human or animal subject, which comprises an antenna for sensing the instantaneous volume of blood in the artery of the subject, to be measured; a RADAR unit for transmitting microwave signals into a subject's body part or limb representing tissue targets. The output of the RADAR unit includes a superposition of signals each of which corresponding to a different tissue target with amplitudes that relate to the target's reflection strength; a sampling circuitry for converting reflected signals to digital; a window function circuitry for suppressing unwanted spectral sidebands originating from the subsequent processor operating on time truncated data; an FFT processor following the window function circuitry, for splitting the superposition according to its relative frequency into a multiplicity of bins, each of which with an amplitude that represents the reflection magnitude of a target at a specific distance from the antenna; a signal processor for filtering out the effect of the sensor movement with respect to the subject body part, or the movement of the body part, and for generating a signal, the amplitude of which is proportional to the artery varying dilatation representing the heart-rate; a heart-rate estimator for measuring the frequency of the artery dilatation variations and for canceling the interference of the amplitude of any signal that does not originate from the artery; a battery for powering the sensor.

An aortic occluder catheter with expandable balloons for increasing cerebral blood blow has one or more balloons on a catheter shaft. To assist the balloon in bearing up against arterial blood flow while positioned retrograde in the aorta, the balloon is bonded to the catheter shaft in tension.

Systems, devices, and methods for organ retroperfusion along with regional mild hypothermia. In at least one embodiment of a method of organ perfusion of the present disclosure, the method comprises the steps of positioning at least part of a first catheter having a cannula within an artery of a patient, the first catheter configured to permit arterial blood to flow therethrough and further configured to permit a portion of the arterial blood to flow through the cannula, positioning at least part of a second catheter within a vein of the patient at or near a target organ, the second catheter configured to receive some or all of the portion of the arterial blood, connecting the cannula of the first catheter to a portion of the second catheter so that some or all of the portion of the arterial blood flowing through the cannula is provided into the vein to treat a condition or disease of the target organ, and reducing and/or regulating a temperature of blood flowing through the cannula using a regional hypothermia system operably coupled to the cannula.

An adaptive tourniquet cuff system comprises: a tourniquet cuff having a physical characteristic and including an inflatable bladder of a length greater than the circumference of a limb at a selected location; a cuff connector carried on the cuff and communicating pneumatically with the bladder for releasably connecting to a tourniquet instrument to establish a gas-tight passageway between the bladder and the tourniquet instrument; and an identifying collar including identification means indicative of the physical characteristic and detectable by the tourniquet instrument upon establishment of the gas-tight passageway. The tourniquet instrument may supply gas to the bladder through the gas-tight passageway at a pressure sufficient to stop arterial blood flow into the limb distal to the cuff at the selected location, and may adapt its operation in response to the detected physical characteristic of the cuff.

This invention describes methods to compute coronary physiology indexes using a high precision registration model, which consists of acquiring coronary angiography images of coronary vessels, performing intravascular imaging, and registering the coronary angiography images with intravascular images to create a high precision registration model, based upon which the coronary flow, fractional flow reserve (FFR) and index of microcirculation resistance (IMR) can be computed. The methods described in this invention to compute coronary flow, FFR, IMR are based on both coronary angiography and intravascular images, and the accuracy is better than those derived from coronary angiography alone or intravascular imaging alone, and have high practical values.

The invention provides a non-invasive blood pressure measuring device and a measuring method thereof. In the device, a main machine is provided with a microprocessor connected with an air pressure sensor; a pressurizing band is an inflatable sac-shaped band with air tubes, is connected with the air pressure sensor, is tied on a limb where the flowing of arterial blood of a measured person can be completely blocked after inflation, and is provided with a pulse wave detector which is fixed at a downstream position of the pressurizing band in the arterial blood flowing direction; and the microprocessor processes a plurality of pulse wave amplitudes detected by the pulse wave detector in the gradual increasing process from zero and corresponding pressurizing band pressure thereof in real time so as to determine the systolic pressure, and processes a plurality of pulse delay time in the process from variation to relative invariant of the delay time between the pulse wave and the corresponding pressure AC signal in real time so as to determine the diastolic pressure. The device converts discontinuous events to continuous measurement, avoids unavoidable possible errors caused by the discontinuity of cardiac impulse, and can accurately and non-invasively measure the systolic pressure and the diastolic pressure in blood pressure.

The invention relates to acquiring information concerning the hemodynamic status of the brain (or any other organ) by measuring and analysing the pulsatile properties of blood flow (velocities) in the organ's feeding vessels in relation to the pulsatile properties of the systemic arterial blood pressure. Provided is a system for the analysis of arterial blood flow velocity measurements, comprising means for receiving input signals delivered by an arterial blood flow velocity (FV) sensor and by an arterial blood pressure (BP) sensor, wherein said FV and BP signals are recorded simulataneously and continuously, further comprising means for processing and outputting signals, wherein said processing comprises calculating the pulsatile apparent resistance (PaR) or the Pulse Flow Velocity Mismatch (PFVM). Plotting PAR or PVFM against mean arterial blood pressure and/or end tidal CO2 levels can serve as an indicator for the effectiveness of imposed therapy.

The present invention discloses an aortic-arch-with-branch covered stent blood vessel combined device. The aortic-arch-with-branch covered stent blood vessel combined device comprises three artificialblood vessel components: (1) a segment of a U-shaped artificial aortic blood vessel with three branches, wherein the main blood vessel at a left part of the branch is internally provided with a stent; (2) small covered stent blood vessels; and (3) a straight cylindrical stent blood vessel with a segment of a bare stent and a segment of a covered stent. The blood vessel components can isolate aortic lesions involving aortic arch and ascending aorta, at the same time rebuild branch arterial blood flow, and can preserve normal blood vessel morphology to a greatest extent. The aortic-arch-with-branch covered stent blood vessel combined device is suitable for various common branch-shaped blood vessels and wide in application ranges, avoids custom stents, can be subjected to mass production, effectively reduces surgical trauma, and is easy in surgery operations.

A technique is disclosed for determining blood flow in a living body by changing the thermal energy level in the venous blood flow path and determining temperatures in both the venous and arterial blood flow paths. Blood flow is calculated as a function of the change in energy level and the temperature differences in the venous and arterial blood flow paths.

A system for Non-Contrast Agent enhanced MR imaging, includes an MR image acquisition device that acquires first and second datasets representing first and second image slabs individually comprising multiple image slices acquired at fast and slow blood flow portions of a heart cycle and oriented substantially perpendicular in at least one axis to direction of vasculature blood flow, in response to a heart cycle synchronization signal. An image data processor processes imaging datasets representing the first and second image slabs to provide first and second volume datasets representing a 3D volume imaged at the fast blood flow portion and the slow blood flow portion respectively and for providing a difference dataset representing an image difference between the first and second volume datasets and enhancing arterial blood flow. A display processor provides data representing an image showing the enhanced arterial blood flow.

Devices, systems, and methods for organ retroperfusion. In at least one embodiment of a method of organ perfusion of the present disclosure, the method comprises the steps of positioning at least part of a first catheter having a cannula within an artery of a patient, the first catheter configured to permit arterial blood to flow therethrough and further configured to permit a portion of the arterial blood to flow through the cannula, positioning at least part of a second catheter within a vein of the patient at or near a target organ, the second catheter configured to receive some or all of the portion of the arterial blood, and connecting the cannula of the first catheter to a portion of the second catheter so that some or all of the portion of the arterial blood flowing through the cannula is provided into the vein to treat a condition or disease of the target organ.

Methods and system are described for multi-parametric, non-invasive, and real-time assessment of blood perfusion and oxygenation in the fetal brain during labor and delivery of a fetus through a vaginal birth canal of a maternal pelvis, and include positioning a probe device in the maternal pelvis during active labor, transmitting and receiving a plurality of ultrasound (US) and photoacoustic (PA) signals between the probe device and fetal brain, displaying in real-time on an US machine communicatively coupled to the probe device one or more images of venous and arterial blood flow of respective blood vessels in the fetal brain, measuring oxygen saturation of the respective venous and arterial blood vessels based on data from the one or more images, and estimating the oxygen measurement in the fetal brain during active labor based on the measured oxygen saturation.

New algorithms to estimate cardiovascular indices by analysis of the arterial blood pressure (ABP) signal. The invention comprises recording and identification of cardiovascular descriptors (including ABP signal, diastolic pressure, systolic pressure, pulse pressure, and end systole), calculation of cardiovascular system parameters, and calculation of aortic blood flow, stroke volume, cardiac output, total peripheral resistance, and characteristic time constant.