Alkaline extract for antibiosis and antiphlogosis, and preparation method thereof

Abstract

The invention discloses an alkaline extract for antibiosis and antiphlogosis, and a preparation method thereof. The alkaline extract for antibiosis and antiphlogosis comprises, by weight, 80-100 parts of a 20-30% alkaloidi sophorae tannate medicine, 10-15 parts of stachydrine and 10-15 parts of berberine. The preparation method comprises the following steps: extraction of the alkaloidi sophorae tannate medicine, extraction of the stachydrine, extraction of the berberine, and preparation of the target alkaline extract. The alkaline extract for antibiosis and antiphlogosis has the advantages of wide application range, multiple effective components, and realization of function complementation and promotion of the effective components, and the preparation method has the advantages of high extraction efficiency, high purity of the obtained product, and easiness in realization.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to an antibacterial and anti-inflammatory alkali extract and a manufacturing method thereof. Background technique [0002] Alkaloids are a type of nitrogen-containing basic organic compounds that exist in nature (mainly plants, but some also exist in animals). They have alkali-like properties, so they were also called pseudoalkali in the past. Most of them have a complex ring structure, and nitrogen is mostly contained in the ring, which has significant biological activity and is one of the important active ingredients in Chinese herbal medicine. Optically active. Some nitrogen-containing organic compounds derived from plants that are not alkaline have obvious biological activity, so they are still included in the scope of alkaloids. And some are derived from natural nitrogen-containing organic compounds, such as certain vitamins, amino acids, and peptides, which are not traditionally c...

AI Technical Summary

Problems solved by technology

[0003] Among the relevant patents that have been applied in China, the patent "An Antibacterial Composition of Matrine and Triazole Fungicides" (application number: 201310680622.9, publication date: 2014-04-16) discloses a kind of matrine and triazole fungicide The antibacterial composition of triazole fungicides, due to its undisclosed manufacturing method, can be assumed to adopt the standard heating water extraction method, without ultrasonic irradiation, and without the "resin adsorption-elution" method for extraction. The efficiency is low, and the purity of the obtained product is low; in addition, due to the lack of active ingredients and non-complementarity (the peribacterium is anti-inflammatory, and the physical properties are inconsistent and can be mixed together), it cannot be applied to many situations, and there is no complementary and mutual promotion effect. More limited

The patent "A tea tree oil-berberine antibacterial composite suspoemulsion and its preparation method" (application number: 201510225029.4, publication date: 2016-06-08) discloses a tea tree oil-berberine antibacterial composite suspoemulsion, due to Among them, tea tree oil is a simple fat-soluble substance, but berberine is a water-soluble substance. The physical properties of the two are not compatible. Therefore, no matter which solvent is used, it can only be made into an uneven suspoemulsion, which affects the accuracy of dosage. Judgment and use, the realization of the whole invention is more difficult