9 results about "Tocotrienol" patented technology

The present invention relates to a process for obtaining minor components from vegetable oils, and wherein the vegetable oil includes palm oil, palm olein, palm mid-fraction or mixtures thereof and wherein the minor components of interest are squalene, tocopherols, and optionally tocotrienols. The process is comprising, a fractionation in short path evaporator followed by a further fractionation in short path evaporator. The feed stream may be a condensate stream from a deodorization step.

This invention relates to a drug delivery composition, a self-emulsifying composition thereof and a method for producing the same for oral administration to enhance the normalisation of fatty liver. More particularly, the self-emulsifying composition comprises a non-ionic surfactant, a co-surfactant, vegetable oil and active ingredients comprising phospholipids, tocotrienols and tocopherols. The composition aforementioned works synergistically to provide an effectively delivered micronutrients and vitamins to the liver and also facilitate hepatic regeneration thereof.

This invention relates to the field of nanomedicine formulation technology, and discloses a ROS-responsive astaxanthin nanoparticle, its preparation method, and its application. The preparation method includes: catalyzing the transketalization reaction of 3-mercaptopropionic acid with 2,2-dimethoxypropane using an alcohol-water tolerant Lewis acid catalyst (preferably scandium trifluoromethanesulfonate) to prepare a thioketal monomer containing dual-terminated carboxyl groups; coupling the thioketal monomer with stearyl alcohol and methoxy polyethylene glycol using a stepwise sequential coupling strategy to construct an amphiphilic polymer with thioketal bonds as ROS-responsive connecting units; co-dissolving the polymer, astaxanthin, and tocotrienols in tetrahydrofuran, and preparing the nanoparticles using a multi-inlet micro-collision flow nanoprecipitation process. The resulting nanoparticles have a particle size of 100 nm to 200 nm, an astaxanthin encapsulation rate of 90% to 99%, and achieve targeted release in response to reactive oxygen species in the pathological microenvironment. Astaxanthin and tocotrienols synergistically exert antioxidant effects.

The present invention relates to a process for obtaining minor components from vegetable oils, and wherein the vegetable oil includes palm oil, palm olein, palm mid-fraction or mixtures thereof. The minor components of interest are squalene, tocopherols, and optionally tocotrienols. The process is comprising, a fractionation in a plate short path evaporator. The fractionation is conducted in a plate short path evaporator with at least one evaporation section at a temperature of 140°C to 180°C, followed by at least one evaporation section at temperature of above 180°C to 240°C. The feed stream may be a condensate stream from a deodorization step.

The application discloses a kind of lipid molecules for nucleic acid delivery and liver microenvironment repair and application, belong to medical biotechnology field, and the lipid molecule is the compound shown in formula (1) or its pharmaceutically acceptable salt, it contains tocopherol or tocol trienol fragment and zinc ion coordination group in its structure, with the chemical and biological function of ionizable lipid and the antioxidant, anti-inflammatory activity of vitamin E and zinc.The lipid nanoparticle comprising the compound can efficiently deliver various nucleic acids, and while releasing in liver target, by eliminating active oxygen, inhibiting inflammatory pathways, actively improving liver microenvironment, reducing oxidative stress and fibrosis damage.The delivery system realizes the synergistic treatment concept of "carrier is medicine", and has wide application prospect in nucleic acid drug treatment and gene vaccine development in chronic liver disease, liver fibrosis, liver cancer and other diseases.

The present invention relates to analogues of non-acidic, fatty, semi-hard fresh cheese and analogues of acidic, fatty, semi-hard fresh cheese, and the production thereof, containing HPO with low saturated fat and sodium content, which confers nutritional and functional characteristics. They are a source of vitamin E in the form of tocotrienol and omega-9 fatty acids.

The present invention relates to a process for obtaining minor components from vegetable oils, wherein the minor components of interest are squalene, tocopherols, and optionally tocotrienols. The process is comprising, an enzymatic condensation of a feed stream in presence of a lipase followed by a fractionation in a plate short path evaporator. The fractionation is conducted in a plate short path evaporator with at least one evaporation section at a temperature of from 140°C to 180°C, followed by at least one evaporation section at temperature of from 180°C to 240°C. The feed stream may be a condensate stream from a deodorization step.

The present invention relates to a process for obtaining minor components from vegetable oils and wherein the vegetable oil includes palm oil, palm olein, palm mid-fraction or mixtures thereof. The minor components of interest are squalene, tocopherols, and optionally tocotrienols. The process is comprising, a fractionation in short path evaporator and a further fractionation in short path evaporator at a temperature of from 180 to 240°C. The feed stream may be a condensate stream from a deodorization step.

The present invention relates to a process for obtaining minor components from vegetable oils, wherein the minor components of interest are squalene, tocopherols, and optionally tocotrienols, wherein the vegetable oil include palm oil, palm olein, palm mid-fraction or mixtures thereof. The process is comprising, an enzymatic condensation of a feed stream in presence of a lipase followed by a fractionation in short path evaporator. The feed stream may be a condensate stream from a deodorization step.