311results about How to "Reduce disease risk" patented technology

The present invention relates to methods of assessing disease susceptibility associated with dietary and lifestyle risk factors. The invention provides for analysis of alleles at loci of genes associated with lifestyle risk factors, and the disease susceptibility profile of an individual is determined by reference to datasets which further match the risk factor with lifestyle recommendations in order to produce a personalized lifestyle advice plan.

The present disclosure provides methods for profiling a microbiome and therapeutic compositions for treatment. Additionally, the methods, systems, compositions and kits provided herein are directed to assessing or predicting health status in a subject. Some of the embodiments include generating a report.

A method of detecting endothelin receptor A mediated coronary microvascular endothelial dysfunction in an asymptomatic subject is disclosed. The method comprises obtaining sets of noninvasive cardiac PET perfusion images of the subject before and after administration of selective endothelin receptor A (ET_A receptor) antagonist. The images are analyzed, including application of applying Markovian homogeneity analysis, and the results are compared to detect improvement, or lack of improvement, of myocardial perfusion homogeneity in the subject. A result of improved myocardial perfusion homogeneity after administration of the antagonist indicates the presence of ET_A receptor-mediated microvascular endothelial dysfunction in the subject and indicates therapeutic treatment to improve endothelial function and/or to reduce coronary artery disease risk factors.

The present invention discloses a cancer-related genes finding method by using miRNA expression data, based on a pan-cancer program PanCancer under The Cancer Genome Atlas (TCGA), and uses statistical analysis and a machine learning algorithm to carry out analysis and processing on the gene expression data, and to identify complex diseases related genes. The method comprises: sorting out sample data; carrying out statistical analysis on the miRNA expression data; sorting miRNA in order of an average change rate; selecting a target gene; extracting a corresponding disease sample and normal sample; and using a Relief algorithm to sort genes in the extracted miRNA sample. The method disclosed by the present invention can find a plurality of risk genes related to cancer and other complex diseases, and has important significance to a biological target therapy, biomedical research, pathogenesis explanation, risk prediction, and the like.

The invention disclosed a 12-lead electrocardiogram detector and a long-range electrocardiogram monitoring and diagnosing system. The 12-lead electrocardiogram detector comprises a lead system, wherein the lead system comprises a wearable lead body and a plurality of electrodes connected to the lead body; the electrodes comprise six fixed electrodes and four movable electrodes, the fixed electrodes are sequentially fixed on the lead body according to the anatomic position of the electrocardiogram detection, and the six fixed electrodes are arranged in the inverted Z-shaped structure. The long-range electrocardiogram monitoring and diagnosing system comprises the 12-lead electrocardiogram detector, an electrocardiogram module connected with the 12-lead electrocardiogram detector to form a whole, and a server system linked with the electrocardiogram module in a wireless manner. According to the 12-lead electrocardiogram detector and the long-range electrocardiogram monitoring and diagnosing system which are disclosed by the invention, the positioning difficulty of the electrodes of the 12-lead detection can be greatly lowered, not only is the measurement accurate, time-saving and effortless, but also the self-diagnosis or the artificial diagnosis can be performed, so that finding the changes of the illness condition of a patient in time is convenient, and corresponding measures are adopted; the electrocardiogram module can perform an early warning for the electrocardiogram allorhythmia, so that the illness risk is reduced.

An endoscopy system (1) comprises an endoscope (2) with a camera (3) at its tip. The endoscope extends through an endoscope guide (4) for guiding movement of the endoscope and for measurement of its movement as it enters the body. The guide (4) comprises a generally conical body (5) having a through passage (105) through which the endoscope (2) extends. A motion sensor comprises an optical transmitter (7) and a detector (8) mounted alongside the passage (105) to measure the insertion-withdrawal linear motion and also rotation of the endoscope by the endoscopist's hand. The system (1) also comprises a flexure controller (10) having wheels operated by the endoscopist. The camera (3), the motion sensor (7/8), and the flexure controller (10) are all connected to a processor (11) which feeds a display.

Compositions and methods of use of annatto extracts [350-450 Dalton molecular weight fraction] including tocotrienols and tocopherols with an appropriate spectrum. This spectrum includes but not limited to low alpha tocopherol, high delta- and gamma-tocols, and mixtures with other extracts [350-450 Dalton molecular weight fraction] like palm and rice and/or nutrients.

The present invention relates to novel triazolo[4,3-a]pyridine derivatives of Formula (I) wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 (“mGluR2”), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.

This invention is directed to a method of growing a plant from the Cannabaceae family, the cultivar or composition produced therefrom, wherein the plant is exposed to artificial lighting of different intensities based on spacing, growth phase, and flowering yield.

The invention relates to a high-performance high-density polyethylene (HDPE) pipe fitting which consists of functional master batches and an HDPE base material. A preparation method is characterized by comprising the following steps of: selecting raw materials, mixing the raw materials, feeding the raw materials under vacuum, drying the raw materials, extruding the raw materials by an inner layer extruder, extruding the raw materials by an outer layer extruder, fixing the diameter by a diameter fixing sleeve, spraying a vacuum sizing box, spraying a cooling water tank, spraying codes by a code sprayer, conveying a product by a caterpillar-tractor, packaging finished products, and detecting the specifications of the HDPE pipe fittings. The HDPE pipe fitting can be produced by using existing equipment and a production technology; the additional value of the products can be increased; the HDPE pipe fitting can be widely applied.

An exercise device for lower body includes a housing defining two compartments, a tread positioned within each compartment, and compression spring assemblies positioned within each compartment. Each tread is supported by and floats on top of its compression spring assembly.

The invention relates to the farm animal husbandry culture field, and especially relates to a green-shell egg layer ecological culture method characterized by comprising the following steps: 1, baby chick selection and brood chamber management; 2, breeding management; 3, egg laying house management; 4, egg laying period feeding management; 5, epidemic prevention health management; 6, chicken manure recovery utilization. The method raises egg layers in a grassplot and a Chinese herbal medicine plot in turns, thus providing rich nutrition components for green-shell egg layers, and realizing large scale ecological farming; the farmed green-shell egg layer is rich in nutrients, high in egg yield, and the egg is rich in nutrient compositions; in addition, the method can realize low carbon processing of chicken manure so as to prepare biomass fuels, thus realizing cycle utilization of the chicken manure, and reducing farming cost.

The invention discloses an antimicrobial-free feed for a nursery pig and a preparation method thereof. The antimicrobial-free feed is prepared from, by weight, 50-55 parts of corn, 5-8 parts of sorghum, 3-5 parts of whey powder, 5-12 parts of expanded soybean, 3-5 parts of fermented soybean meal, 15-20 parts of soybean meal, 3-5 parts of fish meal, 1-2 parts of organic compound acidifier, 1-2 parts of organic mineral premix, 0.03-0.07 part of Chinese herbal medicine additive, 0.02-0.05 part of tea powder, 0.02-0.04 part of orange peel powder, 0.08-0.12 part of hydrolyzed wheat protein powder, 0.5-0.9 part of calcium formate, 0.1-0.5 part of calcium hydrogen phosphate, 0.3-0.5 part of amino acid, 0.1%-0.3% of salt, 0.05-0.2 part of choline chloride, 0.02-0.04 part of vitamin premix, 0.05-0.1 part of complex enzyme preparation and 0.1-0.5 part of mildewproof agent. The antimicrobial-free feed is a green, safe and pollution-free nursing material feed which gives full play to the function of a nursing material for undertaking the period between a weaning feed and a piggy feed, piglet intestinal injuries are well repaired, and the death rate and the incidence risk are decreased; normal growth of piglets is guaranteed, and the optimal growth performance is played.

The invention discloses a creep feed specially used for piglets and a preparation method thereof and belongs to the field of feed production. The creep feed is prepared from following non-thermal-sensitive raw materials and thermal-sensitive raw materials through a two-stage mixing process and a two-stage granulation process, wherein the raw materials includes, by weight, 30-60 parts of corn, 5-12 parts of four, 3-10 parts of puffed soya bean, 3-10 parts of soybean protein concentrate, 1-7 parts of rice protein powder, 8-20 parts of fermented soybean meal, 0.5-3 parts of calcium hydrophosphate, 0.1-0.8 parts of salt, 1.5-5 parts of soybean oil, 3-7 parts of egg powder, 3-10 parts of wheat protein, 5-20 parts of whey powder, 1-5 parts of sugar, 1-5 parts of glucose, 0.3-1.5 parts of lysine, 0.05-0.4 parts of methionine, 0.05-0.5 parts of threonine and 0.5-3 parts of a composite pre-mixed material. Compared with a creep feed in the prior art, the creep feed specially used for the piglets can stop porcine disease transmission caused by plasma protein powder of diseased pigs, is comprehensive in nutrition, is easy to digest and absorb, and is quite good in value of popularization and application.

The invention provides nuclear magnetic resonance visual injectable pH sensitive self-repairing water gel. The gel consists of DTPA-modified chitosan (component A) and polyethylene glycol (component B) of which two ends are subjected to hydroformylation, and the component A solution complexed with Gd<3+> and the component B solution are mixed in a short time at room temperature so as to form in-situ gel. The gel has the pH sensitive self-repairing characteristic, a developing agent is not needed to be repeatedly injected to a patient, and developing can be guaranteed for a long time by using MRI (Magnetic Resonance Imaging), so that the lesion risk caused by Gd<3+> enrichment is reduced. The water gel provided by the invention can serve as drug carriers, embolism or filling materials and tissue scaffold materials in clinical application.

The invention discloses non-reactive organic feed for weaned piglets. The non-reactive organic feed for the weaned piglets is prepared from, by weight, 5-70 parts of corn, 1-20 parts of extruded wheat, 5-15 parts of whey powder, 5-30 parts of broken rice, 5-40 parts of flour, 5-20 parts of extruded soybeans, 5-20 parts of fermented soybean meal, 3-20 parts of milk powder, 1-10 parts of glucose or saccharose, 1-8 parts of fish meal, 1-5 parts of yeast extract, 0.3-2 parts of organic composite acidifier, 0.1-0.4 part of organic mineral substance premix, 0.5-1.5 parts of immunopolysaccharide, 0.1-0.8 part of calcium formate, 0.1-1.5 parts of calcium hydrophosphate, 0.1-1.5 parts of amino acid, 0.1-0.4 part of table salt, 0.05-0.3 part of choline chloride, 0.05-0.2 part of plant essential oil, 0.02-0.05 part of vitamin premix, 0.05-0.2 part of compound enzyme preparation and 0.05-0.5 part of mildew preventive. According to the feed, the immunity of the weaned piglets is fully stimulated, and the death rate and the onset risk are reduced; health and normal development of the gastrointestinal tract are guaranteed, the digestibility of the feed is improved, and the growth performance is improved; environmental pollution is relieved.

The present invention relates to a wild jujube seed oil soft capsule production technology. The production technology comprises the following steps: cleaning wild jujube seeds and removing impurities, carrying out microwave treatment, carrying out low-temperature pressing, filtering, melting glue, pressing pellets, washing pellets, de-fatting, low-temperature drying, sorting pellets, and packaging. The wild jujube seed oil soft capsules are rich in nutrients such as unsaturated fatty acids, vitamin E and various trace elements which can regulate blood fat and improve immunity nutrients, and contains special effective ingredients of the wild jujube seeds which have effects of sedative and hypnotic. The production technology in the present invention has a domestic advanced level, is currently the first which adopts the wild jujube seeds as a raw material and uses of modern science and technology and advanced equipment to extract various nutrients and active ingredients of the wild jujube seeds and then produces high-end products with special health care functions. The wild jujube seed oil soft capsule production technology fills the production and processing technology gaps of such a dual function type of health wild jujube seeds soft capsule for the domestic initiative, and fully meet the needs of industrial production.

A basic material containing pure rapeseed oil for tingle-hot chafing dish in order to regulate blood fat is proportionally prepared from refined rapeseed oil, hot pepper, Chinese prickly ash, ginger, garlic cloves, scallion, gourmet powder, pickled black bean, fermented rice, flavouring wine, crystal sugar, edible salt and 13 Chinese-medicinal materials.

The invention belongs to the technical field of aquaculture and discloses a culture method for double alternate culturing and intercropping lobster and river crab ponds with microptenus salmoides. The method comprises pond preparation, temporary culture of juvenile crabs in a special pond, stocking and culture of lobster seedlings, stocking of microptenus salmoides fries, catching and marketing of lobsters, stocking and culture of juvenile river crabs after temporary culture, utilization of a temporary culture pond, daily management, catching and marketing of river crabs and microptenus salmoides and other steps. The growth characteristics and life habits of the river crabs, the lobsters and the microptenus salmoides are comprehensively considered, the space of the pond is used to culture the lobsters firstly in the early stage of growth of the river crabs, the river crabs are mainly cultured after the lobsters are caught before the end of July, the culture pond is interplanted with microptenus salmoides for control of small trash fish in the pond, and the utilization rate and the economic benefit of a crab pond are increased.

The invention relates to a nutritious compound protein powder, which eliminates the defect that the present food which is used to supplement protein can increase the risk of cardiovascular disease because of the increase of fat and cholesterol. The compound protein powder includes 8-12 shares (by weight) human collagen protein, 8-12 shares (by weight) bovine coloctrum, 250-350 shares (by weight) soybean protein and 550-650 shares (by weight) whey protein.

A highly safe, inexpensive and widely utilizable method, which has a mechanism backed by scientific grounds, for improving an activity of ROS (reactive oxygen species)-scavenging enzyme group; An increase in the amount of an enzyme or promotion of an enzyme activity of the ROS scavenging enzyme group such as superoxide dismutase, catalase or peroxidase is caused in an organism having the ROS-scavenging enzyme with one or two or more kinds of substances selected from the group consisting of erythritol, mannitol, sorbitol and xylitol in 0.01-10% administration concentration.