5 results about "Alpha-Tocopherol" patented technology

The micronutrient compositions are highly effective in the treatment of joint-related inflammation and in the reduction of ECM-disrupting enzymes in the joint, preferably in the treatment of (chronic) arthritis. The micronutrient composition preferably comprises: vitamin C, vitamin E (D-alpha tocopherol), vitamin B6, vitamin D3, folic acid, L-proline, L-lysine, copper, betaine HCl, chondroitin sulfate, N-acetyl-glucosamine, Pycnogenin, SAMe, radix ranunculi ternati, Boswellia serrata, nettle, and glutamine.

The disclosure relates to an oral composition comprising an active ingredient consisting essentially of alpha tocotrienol, gamma tocotrienol, delta tocotrienol, alpha tocopherol and phospholipid in specific percentages for use in liver health optimization. The compositions are stable at room temperature & accelerated storage conditions.

The invention relates to a lacosamide injection and a preparation method thereof. The injection contains lacosamide, a stabilizer, an antioxidant, a complexing agent and a buffer solution. The injection is characterized in that the stabilizer is sodium gluconate, the antioxidant is sodium pyrosulfite, alpha tocopherol and glutathione, the complexing agent is edetate disodium, and the buffer solution is an acetic acid-sodium acetate buffer solution. Meanwhile, the invention discloses a corresponding preparation method. Compared with the prior art, the preparation method has the advantages that the stability of lacosamide is obviously improved, particularly, the generation of two main impurities, namely an impurity D (N-deacetylated lacosamide hydrochloride) and an impurity F (demethylated lacosamide), can be obviously reduced, the quality of a preparation product is improved, the toxic and side effects are reduced, and the preparation method is simple, low in cost and suitable for industrial production. The method is suitable for industrial large-scale production.

The application provides a natural vitamin E purification method. The purification method comprises the following steps: S1, dissolving natural vitamin E in anhydrous ethanol to obtain a vitamin E solution; S2, adding an antioxidant to the vitamin E solution, and then slowly adding a potassium hydroxide solution to perform a saponification reaction to obtain a mixed solution; S3, performing acid neutralization, salt water washing, liquid cyclone separation and dehydration on the mixed solution to obtain crude vitamin E oil; and S4, performing falling film evaporation and short path molecular distillation on the crude vitamin E oil to obtain high-purity natural vitamin E. Through process optimization of a traditional purification process, the process of low-temperature saponification combined with salt water washing and molecular distillation after thin film evaporation is adopted, no residual plasticizer is detected in the purified vitamin E, the content of total tocopherol is higher than 95%, and the proportion of d-alpha tocopherol with high activity in the total tocopherol is more than 50%.

Disclosed is a method and composition for treating non-cirrhotic NASH. A first embodiment of the invention is the administration of a twice daily oral dose of approximately 117-400 mg testosterone equivalent to a subject having liver fibrosis. A second embodiment of the invention is the administration of a once or twice daily oral dose of approximately 117-400 mg testosterone equivalent formulated with approximately 200-600 mg of d-alpha tocopherol equivalent to a subject having liver fibrosis.