The present application provides a novel combination preparation for us in the treatment of acute, chronic and allergic rhinosinusitis which does not cause dry nasal mucosa and is nevertheless very effective in the treatment of the above diseases. The combination preparation comprises an
active ingredient selected from mometasone and / or
fluticasone or a pharmaceutically acceptable salt or solvate of any one of the foregoing, in combination with
dexpanthenol or a pharmaceutically acceptable salt or solvate thereof, as well as a pharmaceutically acceptable
excipient