14 results about "Cholecalciferol" patented technology

The application provides a traditional Chinese medicine granule for improving osteoporosis and a preparation method and application thereof, and belongs to the technical field of medicines. Codonopsis pilosula, drynaria rhizome, epimedium and eucommia are subjected to deep eutectic solvent extraction, purification, and preparation of a traditional Chinese medicine extract, water extraction, dialysis and drying of pilose antler to prepare pilose antler protein peptide; water extraction and alcohol precipitation of cistanche to prepare cistanche polysaccharide; after modification of hydroxyapatite by citric acid, sodium dihydrogen phosphate and beta-cyclodextrin, the product is prepared by inclusion of calcium salt, alpha-cholecalciferol and vitamin D3, and then mixed with the traditional Chinese medicine extract, the pilose antler protein peptide and the cistanche polysaccharide to prepare the traditional Chinese medicine granule for improving osteoporosis. The prepared traditional Chinese medicine granule for improving osteoporosis can promote the synthesis of collagen and bone matrix protein, inhibit bone resorption, promote bone remodeling and enhance the activity of osteoblasts, and has a good improvement effect on osteoporosis, bone fracture and other symptoms, and has a wide application prospect.

The present application relates to the technical field of animal breeding, and discloses a compound nutritional health supplement for laying hens in the egg production period and a preparation and application thereof, which comprises the following raw materials in mass fractions: motherwort 1200-1400 parts, radix astragali 150-250 parts, radix codonopsis 80-120 parts, betaine hydrochloride 500-700 parts, butyric acid clostridium 50-70 parts, bacillus licheniformis 90-110 parts, vitamin acetate 3-5 parts, coated 25-hydroxy-cholecalciferol 1-2 parts, vitamin E acetate 15-25 parts, and rice husk powder 0-411 parts. The formula can scientifically and comprehensively regulate the digestion and absorption of nutrients, immune function and reproductive system health of laying hens, improve the eggshell quality, egg weight and nutritional quality of egg products, has stable effect and strong universality, greatly reduces the side effects and body burden caused by long-term medication while ensuring the effect, and is more suitable for the concept of healthy breeding; the health level of the body is comprehensively improved, the intestinal flora balance is maintained by probiotics, the immunity and stress resistance of laying hens are overall enhanced, the nutrient utilization rate is improved, and healthy high yield is achieved.

The invention discloses a rhizoma polygonati and saussurea involucrata bone marrow peptide tablet and a preparation method thereof, and relates to the technical field of pharmaceutical preparations, the rhizoma polygonati and saussurea involucrata bone marrow peptide tablet comprises the following raw materials by weight: 30%-41% of collagen peptide powder, 26%-28% of L-isoleucine, 16%-19% of a compound nutrition enhancer, 9%-15% of rhizoma polygonati, 3.67%-3.69% of sorbitol, 1%-3% of yak bone marrow peptide powder, 0.1% of emblic leafflower fruit, 0.1% of fructus alpiniae oxyphyllae, 0.1% of mulberry powder, 0.01%-0.03% of a saussurea involucrata culture, and 1% of magnesium stearate. Wherein the compound nutrition enhancer comprises calcium carbonate, maltodextrin and cholecalciferol. Through an innovative raw material pretreatment technology and an intelligent control means, the retention rate and the extraction rate of key components such as polygonatum sibiricum polysaccharide and saussurea involucrata flavone are remarkably improved, the variable coefficients of quality indexes such as hardness, friability and disintegration time limit of the tablet are reduced by 60% or above compared with those of a traditional process, and the product stability is remarkably enhanced.

The invention discloses a method for recovering mother liquor after purification of crude products of vitamin D3 or metabolic derivatives thereof. Comprising the following steps: evaporating mother liquor obtained by purifying a crude cholecalciferol or calcifediol product to remove a solvent so as to obtain an oily concentrate, adding the oily concentrate into high-boiling-point grease, uniformly mixing, and collecting and recovering cholecalciferol or calcifediol by using a molecular distillation technology. According to the method, the molecular distillation technology is utilized to efficiently recover the cholecalciferol or the calcifediol, so that the content of the cholecalciferol or the calcifediol in the cholecalciferol or the calcifediol resin oil is increased to 80% or above, the recovery rate of the cholecalciferol or the calcifediol is 90% or above, the process is simple, the flow is short, the processing process is a physical separation process, and the method is suitable for industrial production. And no chemical substance harmful to the human body is added.

The disclosed invention relates to a chemical composition that can be taken orally and supplements an unhealthy diet and lifestyle. In one aspect of the invention the chemical composition includes Retinol Palmitate, Thiamine, Riboflavin, Niacin, Nicotinamide mononucleotide (NMN), Pyridoxal, Folic Acid, Cyanocobalamin, Cholecalciferol, Zinc, Manganese, Copper, Calcium, Magnesium, Iron, L-Selenomethionine, Lysine, Phenylalanine, L-Threonine, L-Methionine, L-Histidine, L-Tryptophan, L-Leucine, L-Isoleucine, L-Valine, Cinnamon Bark Powder, and Curcumin.

This invention discloses a method for recovering the mother liquor after purifying crude vitamin D3 or its metabolic derivatives. The method includes the following steps: After evaporating the solvent from the mother liquor of crude cholecalciferol or calcidiol, an oily concentrate is obtained. This concentrate is then added to a high-boiling-point oil and mixed thoroughly. Cholecalciferol or calcidiol is then collected and recovered using molecular distillation technology. This invention utilizes molecular distillation technology to efficiently recover cholecalciferol or calcidiol, increasing the cholecalciferol or calcidiol content in the cholecalciferol or calcidiol resin oil to over 80%, with a recovery rate of over 90%. Furthermore, the process is simple, has a short flow, and involves only physical separation without the addition of any harmful chemicals.

The invention provides traditional Chinese medicine granules for improving osteoporosis as well as a preparation method and application thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: performing deep eutectic solvent extraction and purification on codonopsis pilosula, scalded rhizoma drynariae, herba epimedii and eucommia ulmoides to prepare a traditional Chinese medicine extract, and performing water extraction, dialysis and drying on cornu cervi pantotrichum to prepare cornu cervi pantotrichum protein peptide; performing water extraction and alcohol precipitation on cistanche to prepare cistanche polysaccharide; hydroxyapatite is modified by citric acid, sodium dihydrogen phosphate and beta-cyclodextrin, calcium salt, alpha-calciferol and vitamin D3 are included, the prepared product is uniformly mixed with a traditional Chinese medicine extract, cornu cervi pantotrichum protein peptide and cistanche polysaccharide, and the traditional Chinese medicine granules for improving osteoporosis are prepared. The prepared traditional Chinese medicine granules for improving osteoporosis can promote synthesis of collagen and bone matrix protein, inhibit bone resorption, promote bone remodeling and enhance the activity of osteoblasts, have a very good improvement effect on symptoms such as osteoporosis and fracture, and have a wide application prospect.

Disclosed are methods for increasing a patient's levels of vitamin D through transdermal administration of cholecalciferol. The patient may be identified as being at risk of calcidiol accumulation, such as having chronic kidney disease or being at risk of developing chronic kidney disease. The patient is administered a transdermal formulation of cholecalciferol. The transdermal formulation beneficially increases serum calcitriol in the patient without disproportionally accumulating serum calcidiol.

The invention relates to the pharmaceutical industry and can be used for creating a medicinal preparation or dietary supplement for the prophylaxis and treatment of calcium deficiency and osteoporosis. The essence of the invention consists in a composition for the prophylaxis and treatment of calcium deficiency and osteoporosis which contains tribasic calcium phosphate, magnesium hydroxide, cholecalciferol, pyridoxine hydrochloride, resveratrol, astragaloside IV, sodium selenate, zinc oxide and sodium borate. The technical result of the invention lies in more effective prophylaxis and treatment of calcium deficiency and osteoporosis, together with increased calcium absorption into bone tissue, as well as in a tailored medical effect which consists in preventing loss of bone mass in postmenopausal women with no obvious symptoms of osteoporosis.

The application discloses a sugar-free endurance sports food and a preparation method thereof. Product raw materials include retinol acetate oil, cholecalciferol oil, dl-alpha-tocopherol acetate oil, thiamine hydrochloride, riboflavin, pyridoxal hydrochloride, L-ascorbic acid, caffeine, taurine, magnesium sulfate, zinc gluconate, selenium-rich yeast, chromium-rich yeast, emulsifier, sweetener, acidity regulator and dietary fiber. The preparation process is prepared by spray drying and mixing of raw materials, and the raw materials include trace nutrients, emulsifiers, sweeteners, acidity regulators and dietary fibers. Modern granulation, embedding and slow-release preparation technologies are utilized to continuously provide nutrition during sports and realize true sugar-free. The raw materials only contain a small amount of Na + , and will not affect the osmotic pressure of the human body, and are more suitable for supplementing endurance sports.

Provide improved means for transdermally delivering a pesticidal or other toxic agent from a composition containing the toxic agent to a target animal, particularly into its bloodstream. **Solution**: A composition for killing animals, such as rodents, comprising (i) one or more toxic agents toxic to the animal, such as cholecalciferol or 25-hydroxy cholecalciferol (vitamin D3), as a toxic component, and (ii) a carrier system for the toxic component, wherein the carrier system (ii) comprises (a) at least one solvent or dispersion medium for the toxic component, such as an alcohol like ethanol, and (b) at least one skin disrupting component, such as dimethyl sulfoxide (DMSO). The composition enhances the skin penetration of the toxicant into or through the skin of the animal where the composition is sprayed or delivered, for example, in a trap or other device. ​

The present invention relates to stable compositions of Cholecalciferol (Vitamin D3) and process of preparation thereof. The stable compositions of the present invention are obtained by spray drying of Vitamin D3 emulsion.

The present invention discloses plant based vitamin D3 (Cholecalciferol) that meets the pharmacopeia standard as well as "Green dot" specification. The present invention further discloses a commercial process for preparation of plant based vitamin D3 from plant sourced bisnoralcohol with improved yield and purity. The bisnoralcohol used as a starting material in the present process is obtained from soyabean oil deodorizer distillate (SODD). The vitamin D3 prepared by the present process is 100% vegetarian and provides the missing nutritional source of Vitamin D3 to a large number of vegetarian and vegan population.

A functional food composition for attenuating age-related cognitive decline comprises multiple synergistic and additive nutrient components formulated to mimic Mediterranean and MIND dietary patterns. The composition includes omega-3 fatty acids in phospholipid form from herring roe oil, fat-soluble vitamins including cholecalciferol and tocopherols, carotenoids from marigold extract, B-vitamins including nicotinamide and hydroxocobalamin, magnesium bisglycinate chelate, polyphenolic compounds including catechins, flavonols, anthocyanins, and pterostilbene from various plant sources, and I-theanine. The composition achieves greater than 80% nutrient bioavailability through specialized delivery systems, including immediate-release capsules, delayed-release enteric capsules, and lipophilic softgels. Administration for 4-52 weeks to adults aged 50-90 years with suboptimal dietary patterns produces measurable improvements in biomarkers of cognitive health. A systematic method for developing such compositions based on dietary pattern analysis and multi-criteria nutrient scoring. Additionally, a method of inducing changes in important markers for brain aging and disease using a dietary pattern directed nutritional supplementation regimen.