The invention relates to the field of biological pesticides, in particular to a
plant-source environment-friendly
rodenticide and a preparation method thereof, and the
plant-source environment-friendly
rodenticide is prepared from the following raw materials: modified
chitosan, a modified oleander extract,
oxalate,
caffeine, EDTA,
capsaicin,
rapeseed oil, peanuts, clover and a garlic extract. The modified
nerium oleander extract, the modified
chitosan and the
oxalate play a role through a synergistic effect, the modified
nerium oleander extract can be combined with a
sodium-
potassium pump on a heart
cell membrane to inhibit the activity of the
sodium-
potassium pump, and the modified
chitosan enables
cell permeability to be improved, so that the
concentration gradient of ions inside and outside the heart
cell membrane is increased; the
oxalate further maintains the
ion concentration gradient inside and outside the membrane, finally the function of the
sodium-
potassium pump is damaged, normal operation of the sodium-potassium pump is interfered through the combined action of the oxalate, the oxalate and the sodium-potassium pump,
heart failure and death of mice are caused, the oxalate, the sodium-potassium pump and the sodium-potassium pump form a
dynamic balance system, the
ecological environment is effectively protected, and the problems of the mice are solved to a great extent. A healthy and environment-friendly
pesticide is provided for
agriculture, forest land and the like.