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32 results about "Oxygen radical absorbance capacity" patented technology
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Oxygen radical absorbance capacity (ORAC) was a method of measuring antioxidant capacities in biological samples in vitro. Because no physiological proof in vivo existed in support of the free-radical theory or that ORAC provided information relevant to biological antioxidant potential, it was withdrawn in 2012.
Topical macqui berry formulation
InactiveUS20070065396A1High ORACImprove antioxidant capacityBiocideCosmetic preparationsMedicineOxygen radical absorbance capacity
The present invention provides a topical formulation and method of use where the formulation comprises macqui berry or a macqui berry extract containing anthocyanins having a very high oxygen radical absorbance capacity (ORAC). The formulation provides the macqui berry in a stabilized form which includes a glucuronide or glycuronide, a photostabilizing agent, encapsulation, or light -and / or air-blocking packaging.
Owner:TRACIE MARTYN INT
Formulation to enhance antioxidant potency of Vitamin E
InactiveUS7015245B2Improve antioxidant capacityGood synergyCosmetic preparationsBiocideDiseaseOxygen radical absorbance capacity
A formulation to deliver a full-spectrum of Vitamin E isomers for improved antioxidant capacity, bioavailability, dissolution and efficacy. The formulation includes dl-α-tocopheryl acetate or dl-α-tocopheryl succinate (synthetic Vitamin E), natural Vitamin E and mixed tocopherols, such as α-, β-, γ- and δ-tocopherol, as well as four isomers (α, β, γ and δ) of tocotrienols. This formulation is designed to deliver at least 17-times the antioxidant capacity of synthetic Vitamin E (dl-α-tocopheryl acetate), and at least twice the antioxidant capacity of natural Vitamin E (d-α-tocopherol) as measured by oxygen radical absorbance capacity (ORAC) assay. The potent antioxidant capacity of this formula affords protection against oxidative damage of cell membranes, heart disease, cancer and eye and skin disease.
Owner:RICH MELVIN +2
Walnut protein antioxidant peptides and preparation method thereof
ActiveCN103497985AHigh activityStrong antioxidant peptide activityFermentationTripeptidesAbsorption capacityFiltration
The invention relates to walnut protein antioxidant peptides and a preparation method thereof. The preparation method comprises: hydrolyzing walnut protein by an enzymatic method to obtain a walnut protein enzymatic hydrolysate, then using gel filtration chromatography and reversed-phase high-performance liquid chromatography to perform separation and purification to obtain fourteen new antioxidant peptide products, and determining the amino acid sequences of the products. The prepared antioxidant peptides have extremely strong antioxidative effect, and high oxygen radical absorption capacity which is 4 times of that of crude peptides; and moreover, the peptides have the characteristics of being low in molecular weight and directly absorbable by a human body, and thus the antioxidant peptides are widely applicable to the fields of foods, healthcare products, cosmetics, and the like.
Owner:广东华肽生物科技有限公司
Synsepalum dulcificum Denill tree branch and leaf extract and extraction method and application of extract
InactiveCN102743421AImprove cleanlinessStrong absorption capacityAntinoxious agentsSkeletal disorderFreeze-dryingOxygen radical absorbance capacity
The invention relates to an extraction method for a Synsepalum dulcificum Denill tree branch and leaf extract. The extraction method comprises the following steps of: crushing Synsepalum dulcificum Denill tree branches and leaves to obtain an extracted raw material; adding ethanol water; performing reflux extraction for 2-5 hours; filtering; performing reduced pressure distillation on supernate; performing freeze drying to obtain branch and leaf crude extract dry powder; dissolving the branch and leaf crude extract dry powder in water; performing macroporous resin treatment; then, eluting by using the ethanol water to obtain drips; and respectively performing vacuum concentration and the freeze drying to obtain a refined branch and leaf extract. The total phenol content of the obtained extract is 66.5 percent, and the total phenol content of a branch extract is 84.1 percent. The diphenylpicrylphenylhydrazine (DPPH) scavenging activity of the extract is 7.9 and 7.8 times of that of glutathione, and the oxygen radical absorbing capacity of the extract is 7.0 and 6.2 times of that of the glutathione. The extract is good in inhibitory activity on xanthine oxidase and can be used for preparing antioxidants, gout suppressants and health-care products.
Owner:万福群
Formulation and delivery method to enhance antioxidant potency of Vitamin E
InactiveUS20060106093A1Improve antioxidant capacityGood synergyBiocideCosmetic preparationsOxygen radical absorbance capacityCell membrane
A formulation to deliver a full-spectrum of Vitamin E isomers for improved antioxidant capacity, bioavailability, dissolution and efficacy. The formulation includes dl-α-tocopheryl acetate or dl-α-tocopheryl succinate (synthetic Vitamin E), natural Vitamin E and mixed tocopherols, such as α-, β-, γ- and δ-tocopherol, as well as four isomers (α, β, γ and δ) of tocotrienols. This formulation is designed to deliver at least 17-times the antioxidant capacity of synthetic Vitamin E (dl-α-tocopheryl acetate), and at least twice the antioxidant capacity of natural Vitamin E (d-α-tocopherol) as measured by oxygen radical absorbance capacity (ORAC) assay. The potent antioxidant capacity of this formula affords protection against oxidative damage of cell membranes, heart disease, cancer and eye and skin disease.
Owner:SOFT GEL TECHNOLGIES
Formulation and delivery method to enhance antioxidant potency of Vitamin E
InactiveUS7012092B2Improve antioxidant capacityGood synergyOrganic active ingredientsBiocideDiseaseOxygen radical absorbance capacity
A formulation to deliver a full-spectrum of Vitamin E isomers for improved antioxidant capacity, bioavailability, dissolution and efficacy. The formulation includes dl-α-tocopheryl acetate or dl-α-tocopheryl succinate (synthetic Vitamin E), natural Vitamin E and mixed tocopherols, such as α-, β-, γ- and δ-tocopherol, as well as four isomers (α, β, γ and δ) of tocotrienols. This formulation is designed to deliver at least 17-times the antioxidant capacity of synthetic Vitamin E (dl-α-tocopheryl acetate), and at least twice the antioxidant capacity of natural Vitamin E (d-α-tocopherol) as measured by oxygen radical absorbance capacity (ORAC) assay. The potent antioxidant capacity of this formula affords protection against oxidative damage of cell membranes, heart disease, cancer and eye and skin disease.
Owner:RICH MEL +2
Topical Macqui Berry Formulation
ActiveUS20120114719A1Improve skinCosmetic preparationsBiocideMedicineOxygen radical absorbance capacity
The present invention provides a topical formulation and method of use where the formulation comprises macqui berry or a macqui berry extract containing anthocyanins having a very high oxygen radical absorbance capacity (ORAC). The formulation provides the macqui berry in a stabilized form which includes a glucuronide or glycuronide, a photostabilizing agent, encapsulation, or light- and / or air-blocking packaging.
Owner:TRACIE MARTYN INT
Process for preparing antioxidative peptide and antifreeze peptide through enzymatic hydrolysis of salmon collagens
InactiveCN108118077ADifferent biological activitiesLow costConnective tissue peptidesHydrolasesOxygen radical absorbance capacityFiltration
The invention discloses a process for simultaneously preparing an antioxidative peptide and an antifreeze peptide through enzymolysis of collagens. The method comprises the following steps: extractingcollagens by taking salmon skin as a raw material, hydrolyzing the collagens into a short peptide solution by utilizing crude enzymes of extracellaluar protease obtained by fermentation of Vibrio sp.SQS2-3, performing centrifugal ultrafiltration by a 3000 Da ultrafiltration tube 4500*g for 45 minutes so as to obtain the antifreeze peptide with effects of protecting myosin and relieving decreaseof Ca<2+>-ATPase activity in multigelation, performing Sephadex LH-20 gel filtration chromatography to separate lower ultrafiltration components so as to obtain the antioxidative peptide which has effects of scavenging DPPH free radicals and hydroxyl radicals and a certain ability of inhibiting DNA oxidative damage and shows concentration-dependent antioxidant activity in oxygen radical absorptioncapacity detection. The LC-MS technology shows that the antioxidant component contains 19 polypeptides.
Owner:CENT SOUTH UNIV
Nutritional supplement to enhance learning, academic, and behavioral functioning
InactiveUS7771756B1Easy to learnBehavioral improvementOrganic active ingredientsBiocideOxygen radical absorbance capacityOxygen
A nutritional supplement to improve learning, academic, and behavioral performance, particularly of children in academic settings, comprising a quantity of flavonoid compounds with oxygen radical absorbance capacity (ORAC) derived from a multitude of plant substances, lipoic-carotenoid compounds, and a neurotransmitter amino acid.
Owner:SCHLESSER JERRY L
Antioxidant peptide and preparation method thereof
ActiveCN102660615AWide variety of sourcesLow pricePeptide preparation methodsFermentationEnzymatic hydrolysisFluid phase
The invention relates to antioxidant peptide and a preparation method thereof. According to the preparation method, peanut meal enzymolysis liquid is obtained by utilizing peanut meal and self-made koji-forming enzymes and through enzymatic hydrolysis; then the peanut meal enzymolysis liquid is separated and purified by utilizing an ultrafiltration membrane, a gel filtration chromatograph and a reversed-phase high-performance liquid chromatograph, so as to obtain a new antioxidant peptide product; and the amino acid sequence of the new antioxidant peptide product is determined. The amino acid sequence of the product is Tyr-Gly-Ser, and the molecular weight of the product is 325.3Da; the product has very strong antioxidant effect, and the oxygen free radical absorption capability of the product is 4 times of that of reduced glutathione; and the antioxidant peptide has the characteristic of small molecular weight and can be directly absorbed by human bodies, so that the antioxidant peptide can be widely applied to the fields of foods, health care products, cosmetics, and the like.
Owner:SOUTH CHINA UNIV OF TECH
Antioxidant peptide and preparation method and application thereof
ActiveCN111647072AImproves antioxidant activityRealize high-value utilizationConnective tissue peptidesAntinoxious agentsMyofibrillaOxygen radical absorbance capacity
The invention discloses an antioxidant peptide and a preparation method and application thereof, and aims to provide an antioxidant peptide which is derived from chicken breast myofibrillar protein and has high-efficiency antioxidant activity, and a preparation method and application thereof. The amino acid sequence of the antioxidant peptide is ITTNPYDY or IGWSPLGSL. The preparation method of theantioxidant peptide comprises the following steps of: extracting the myofibrillar protein from fresh chicken breast serving as a raw material; performing enzymolysis on the obtained myofibrillar protein by using pepsin; and performing separation, purification and synthesis to obtain the antioxidant peptide. The antioxidant peptide is a novel antioxidant peptide, and has high antioxidant activitythrough detection; under the measuring condition, the iron ion reducing capacity and the oxygen radical absorbing capacity of the antioxidant peptide are obviously higher than those of glutathione; and meanwhile, the antioxidant peptide has an obvious effect of inhibiting the oxidative damage of NIH-3T3 cells. The antioxidant peptide belongs to a natural antioxidant, is safer to eat, and can be applied to food, health-care products and medicaments with antioxidant functions.
Owner:TIANJIN UNIV OF COMMERCE
Amino acid and plant compound composition for relieving alcoholism and protecting liver and application thereof in foods and health foods
InactiveCN103519164AReduce generationHigh ability to scavenge free radicalsFood preparationFood ingredient as emulsifierAlcoholismsEthanol dehydrogenase
The invention relates to a composition for relieving alcoholism and protecting liver. The composition is prepared from the following raw materials in parts by weight: 2-3 parts of L-cysteine, 3-6 parts of taurine, 8-12 parts of glycine, 10-20 parts of curcumin, 10-20 parts of silymarin and 30-60 parts of quercetin. An in-vitro alcohol dehydrogenase (ADH) activity test and an oxygen radical absorbance capacity (ORAC) test prove that the composition disclosed by the invention has the capacity of instantly and effectively improving the activity of alcohol dehydrogenase (ADH) and accelerating ethanol metabolism, and can be used for efficiently clearing free radicals, reducing oxidative damages caused by ethanol and simultaneously preventing adverse outcomes including drunkenness, dizziness, alcoholic liver injuries and the like caused by one-time heavy drinking and long-term drinking. The composition can be prepared into foods and health foods with functions of relieving alcoholism and protecting liver, and can be used as an auxiliary product and the like for instantly relieving alcoholism and protecting the liver for a long time.
Owner:北京中科邦尼国际科技有限责任公司
Antioxidative peptide and preparation method for same
InactiveCN103276039AHigh activitySmall molecular weightPeptide preparation methodsDipeptidesHylarana guentheriAbsorption capacity
The invention relates to an antioxidative peptide and a preparation method for the same. A novel antioxidative peptide product is prepared by hydrolyzing hylarana guentheri proteins via an enzymic method to obtain hylarana guentheri protein enzymatic hydrolysate, and performing separation and purification on the hylarana guentheri protein enzymatic hydrolysate by virtue of an ultrafiltration membrane, an ion exchange chromatography, a gel filtration chromatography and a reversed-phase high-performance liquid chromatography, and the amino acid sequences of the product are determined. The amino acid sequences of the product are Leu-Lys(259.1607Da) and Phe-Lys(293.1446Da), as well as have an antioxidative effect, and high oxygen radical absorption capacities which are 7.83 times and 15.78 times than crude peptides; and moreover, the peptide has the characteristics of being low in molecular weight, and capable of being directly absorbed by a human body, thus being capable of being widely applied to the fields of foods, healthcare products, cosmetics, and the like.
Owner:SOUTH CHINA UNIV OF TECH
Methods for boosting uva photo-protection using antioxidants
ActiveUS20190298638A1Prevent skinImprove skin appearanceCosmetic preparationsToilet preparationsOxygen radical absorbance capacityPhoto protection
Methods for providing broad spectrum photo protection to skin using antioxidants that provide UVA protection to skin are described. The methods include topically applying a cosmetic composition comprising: (a) at least one antioxidant having an Oxygen Radical Absorbance Capacity (ORAC) of at least 10,000 μmol TE / g and a Hydroxyl Radical Absorbance Capacity (HORAC) of at least 2,600 μmol GAE / g; (b) at least one organic UV filter; and (c) a cosmetically acceptable carrier; wherein the cosmetic composition provides an increase in UVAPPD PF of at least 30% relative to an otherwise identical cosmetic composition without the antioxidant(s) of (a). The disclosure also relates to the cosmetic compositions useful in the described methods.
Owner:LOREAL SA
Method for discriminating true and false of propolis through combination of fingerprint spectrum and antioxidation activity
The invention discloses a method for discriminating true and false of propolis through combination of fingerprint spectrum and antioxidation activity, which belongs to the quality discriminating of traditional Chinese medicine raw material quality control category, and specially relates to the method for identifying the true and false of the propolis raw material and its product by the high-pressure liquid-phase fingerprint spectrum and special antioxidation characteristic of the propolis. The method comprises three steps of fingerprint spectrum determination, oxyradical absorption capabilitydetermination and sample identification. Under same test condition, the fingerprint spectrum of a sample is compared with the fingerprint spectrum for simultaneously detecting the propolis and a poplar gum sample, several characteristic peaks in the fingerprint spectrum of the sample are selected, and true, false or adulteration of the propolis can be determined by convenient comparison and resultdetermination. The antioxidation specific index limitation and the fingerprint spectrum are combined for identifying the true, false or adulteration of the propolis.
Owner:SHANGHAI JIAODA ONLLY CO LTD
Polypeptide with antioxidant activity and liver protection activity, polypeptide coding gene as well as preparation method and application of polypeptide
ActiveCN109096368AAvoid damageDigestive systemTetrapeptide ingredientsOxygen radical absorbance capacityCell damage
The invention discloses a polypeptide with antioxidant activity and liver protection activity, a polypeptide coding gene as well as a preparation method and an application of the polypeptide. The amino acid sequence of the polypeptide is Tyr-Phe-Leu-Pro. According to ORAC (oxygen radical absorbance capacity) experiment evaluation for antioxidation capacity of the synthetic peptide, ethanol can induce a certain degree of damage to liver cells (LO2), an LO2 cell damage model is used for evaluating the liver protection effect of the synthetic peptide, and results show that the synthetic peptide can reduce the damage effect of ethanol on the LO2 cells and has wide application prospect in preventing and treating ALD (alcoholic liver disease).
Owner:SOUTH CHINA UNIV OF TECH
Processing method of black Chinese wolfberry fruits
Owner:CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
Frosted walnut kernels and preparation method thereof
InactiveCN107568396AReduce greasy feelingORACImprovedConfectionerySweetmeatsAdditive ingredientOxygen radical absorbance capacity
The invention discloses frosted walnut kernels and a preparation method thereof. Making raw materials of the frosted walnut kernels comprise the following components of walnut kernels, plant raw materials having functions of clearing heat and removing toxicity, snow pear juice, white sugar, milk powder, citric acid, frosting fluid and frost powder, wherein the frost powder comprises white sugar powder and menthol powder. According to the frosted walnut kernels disclosed by the invention, the ingredients having the efficacy of clearing heat, removing toxicity, reducing pathogenic fire and diminishing inflammation, such as the snow pear juice, honeysuckle flowers, chrysanthemum flowers, mint leaves and menthol, are added, so that the ORAC (oxygen radical absorbance capacity) of products is improved, the frosted walnut kernels not only can have a certain function of reducing internal heat but also can provide refreshing mouth feel, and the intrinsic greasy feel of walnut nuts can be reduced.
Owner:杭州姚生记食品有限公司
Purple perilla seed anti-oxidizing heptapeptide and preparation method of same
ActiveCN106243191AImprove cleanlinessReduce peroxidation rateFood ingredient as antioxidantFood preservationFood additiveReactive oxygen radicals
The invention provide a purple perilla seed anti-oxidizing heptapeptide and a preparation method of same. The anti-oxidizing heptapeptide has the following sequence: Ser-Gly-Pro-Val-Gly-Leu-Trp (SGPVGLW). An in-vitro test proves that the heptapeptide can effectively remove ABTS and has a strong oxygen radical absorbance capacity (ORAC); and meanwhile, the heptapeptide can effectively inhibit lipid peroxidization of linoleic acid. A cellular test proves that the heptapeptide is safe to cells, and has significant inhibiting effects on oxidative damage of HepG-2 cells. The anti-oxidizing heptapeptide has simple structure, is safe and has strong anti-oxidizing activity, can be used as an excellent replacement of artificially synthesized anti-oxidizing agent, and has an important value in the fields of development and application of novel anti-oxidizing health-caring products and food additives.
Owner:FUZHOU UNIV
Application of spina gleditsiae to preparation of antioxidant or nitric oxide release inhibitor
InactiveCN109331057AImproves antioxidant activityHigh activityAntipyreticAnalgesicsOxygen radical absorbance capacityRutin
The invention provides application of spina gleditsiae to preparation of an antioxidant or a nitric oxide release inhibitor. By virtue of two in-vitro antioxidant activity evaluation methods such as aDPPH (1,1-Diphenyl-2-Picrylhydrazyl) radical scavenging method and an oxygen radical absorbance capacity (ORAC) method and an activity test for inhibiting NO release of rat macrophages, results showthat compared with rutin, hawthorn extract and other substances, the spina gleditsiae has equivalent or even higher activity, can serve as a novel antioxidant or nitric oxide release inhibitor to be used, and provides a novel conception and strategy for developing novel antioxidant drugs.
Owner:SHENZHEN INST FOR DRUG CONTROL SHENZHEN TESTING CENT OF MEDICAL DEVICES
Antioxidant peptide of walnut meal and preparation method thereof
ActiveCN103497985BHigh activityStrong antioxidant peptide activityFermentationTripeptidesAbsorption capacityHydrolysate
The invention relates to walnut protein antioxidant peptides and a preparation method thereof. The preparation method comprises: hydrolyzing walnut protein by an enzymatic method to obtain a walnut protein enzymatic hydrolysate, then using gel filtration chromatography and reversed-phase high-performance liquid chromatography to perform separation and purification to obtain fourteen new antioxidant peptide products, and determining the amino acid sequences of the products. The prepared antioxidant peptides have extremely strong antioxidative effect, and high oxygen radical absorption capacity which is 4 times of that of crude peptides; and moreover, the peptides have the characteristics of being low in molecular weight and directly absorbable by a human body, and thus the antioxidant peptides are widely applicable to the fields of foods, healthcare products, cosmetics, and the like.
Owner:广东华肽生物科技有限公司
Antioxidant Agent and Beverage Using Same
InactiveUS20090246344A1Increase valueEasily enhancing the intake of ORAC and a beverageFatty substance preservation using additivesTeaAntioxidantOxygen radical absorbance capacity
An antioxidant agent capable of easily enhancing the intake of ORAC (Oxygen Radical Absorbance Capacity) is proposed. The antioxidant agent includes tealeaf as an active ingredient for enhancing ORAC. The tealeaf is preferably plucked from tea Camellia sinensis, decaffeinated or in a powdery form having a median diameter equal to or less than 50 μm. A beverage using such antioxidant agent is also proposed.
Owner:SASAKI TEA MFG
A kind of processing method of black fruit wolfberry
The invention discloses a processing method of black Chinese wolfberry fruits. The processing method of the black Chinese wolfberry fruits comprises the following steps: preparing an alcohol solution of which the concentration is higher than 70% (v / v) and the temperature is 18-25 DEG C, and utilizing the alcohol solution as a washing solution; washing the black Chinese wolfberry fruits in the washing solution, wherein the washing time is 0.5-60 minutes; drying the washed black Chinese wolfberry fruits until no moisture is on surfaces of the black Chinese wolfberry fruits; and heating the processed black Chinese wolfberry fruits by microwave. The processing method of the black Chinese wolfberry fruits disclosed by the invention is highly effective and simple, and is capable of obviously reducing total numbers of colonies of the black Chinese wolfberry fruits, so that the processing method has good sterilizing effects; moreover, the processing method is also capable of greatly reducing anthocyanin losses during the washing processes of the black Chinese wolfberry fruits. The black Chinese wolfberry fruits processed by the processing method have the following advantages: the total numbers of colonies are smaller or equal to 1.5 plus 102 (CFU / g), the anthocyanin loss rates are kept under 5%, and the oxygen radical absorbance capacities are 400-700 micromoles TE / gram; and the prepared black Chinese wolfberry fruits are fresh and bright in color and luster, safe and reliable to human body, green and environment-friendly.
Owner:CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
A synthetic polypeptide, its synthetic method and application, and a gene encoding the synthetic polypeptide
ActiveCN108752421BReduced survival rateHas antioxidant capacityDigestive systemTetrapeptide ingredientsOxygen radical absorbance capacityLiver disease
The invention discloses a synthetic polypeptide, its synthesis method and application, and a gene encoding the synthetic polypeptide. The amino acid sequence of the polypeptide is: Leu-Val-Tyr-Pro, as shown in the sequence table SEQ ID No:1. The polypeptide of the present invention is synthesized by a solid-phase synthesis method using a polypeptide synthesizer. The polypeptide of the present invention has passed the oxygen free radical absorption capacity test (ORAC), and the result shows that it has a certain antioxidant capacity. This polypeptide was applied to the ethanol-induced liver injury cell model, and its protective effect on LO2 cells was tested by MTT assay. The results showed that it could inhibit the decrease in the survival rate of LO2 cells induced by ethanol, and had a certain liver-protecting effect, which can be applied to protect Alcoholic liver disease direction.
Owner:SOUTH CHINA UNIV OF TECH
Data acquisition method and heating system for oxygen radical absorbance capacity measuring analyzer
ActiveCN102507522BReduce mistakesSmall coefficient of variationHeating or cooling apparatusFluorescence/phosphorescenceData setAssay
The invention relates to an antioxidant capacity analyzing tester in the field of analyzing testers, in particular to a data acquisition method and a heating system for an oxygen radical absorbance capacity (ORAC) measuring analyzer. A method for acquiring data by scanning is adopted on a data acquisition system with a positive temperature coefficient (PTC) constant temperature heating system, namely in a measured tube diameter range of a certain data acquisition point, data sets are acquired by scanning in a short period of time, and the maximum data acquired by scanning in the short period of time is selected as data acquired at the time point. By the invention, the coefficient of variation of the data sets acquired by the type of instruments can be obviously reduced on statistical significance, so that errors of a measurement result within assays and a measurement result between assays are directly reduced obviously.
Owner:上海智城分析仪器制造有限公司
Synthetic polypeptide, synthesis method and application of synthetic polypeptide, and gene encoding the synthetic polypeptide
ActiveCN108752421AImprove hydrogen supply capacityHigh ORAC activityDigestive systemTetrapeptide ingredientsSynthesis methodsOxygen radical absorbance capacity
The invention discloses a synthetic polypeptide, a synthesis method and an application of the synthetic polypeptide, and a gene encoding the synthetic polypeptide. The amino acid sequence of the polypeptide is Leu-Val-Tyr-Pro and is shown as in a sequence table SEQ ID No:1. The polypeptide is synthesized through solid-phase synthesis by using a polypeptide synthesizer. The oxygen radical absorbance capacity (ORAC) experiment is conducted on the polypeptide, and the result shows that the polypeptide has certain antioxidant ability. The polypeptide is applied to an ethyl alcohol induced liver injured cell model, an MTT (Methyl Thiazolyl Tetrazolium) detection method is used to verify the protection action of the polypeptide on an LO2 cell, the result shows that the polypeptide inhibits the ethyl alcohol induced LO2 cell to reduces the survival rate, and the polypeptide has a certain effect on protecting the liver and is applied to the protecting the alcoholic liver disease.
Owner:SOUTH CHINA UNIV OF TECH
A perilla seed antioxidant heptapeptide and preparation method thereof
ActiveCN106243191BImprove cleanlinessReduce peroxidation rateFood ingredient as antioxidantFood preservationFood additiveLipid formation
The invention provide a purple perilla seed anti-oxidizing heptapeptide and a preparation method of same. The anti-oxidizing heptapeptide has the following sequence: Ser-Gly-Pro-Val-Gly-Leu-Trp (SGPVGLW). An in-vitro test proves that the heptapeptide can effectively remove ABTS and has a strong oxygen radical absorbance capacity (ORAC); and meanwhile, the heptapeptide can effectively inhibit lipid peroxidization of linoleic acid. A cellular test proves that the heptapeptide is safe to cells, and has significant inhibiting effects on oxidative damage of HepG-2 cells. The anti-oxidizing heptapeptide has simple structure, is safe and has strong anti-oxidizing activity, can be used as an excellent replacement of artificially synthesized anti-oxidizing agent, and has an important value in the fields of development and application of novel anti-oxidizing health-caring products and food additives.
Owner:FUZHOU UNIV
A kind of antioxidant peptide and its preparation method and application
ActiveCN111647072BImproves antioxidant activityPromote absorptionConnective tissue peptidesAntinoxious agentsMyofibrillaOxygen radical absorbance capacity
The invention discloses an antioxidant peptide, its preparation method and application, and aims to provide an antioxidant peptide with high-efficiency antioxidant activity derived from chicken breast myofibrillar protein, its preparation method and application. The amino acid sequence of the antioxidant peptide of the present invention is ITTNPYDY or IGWSPLGSL. The preparation method of the antioxidant peptide comprises the following steps: extracting myofibrillar protein from fresh chicken breast meat, enzymatically hydrolyzing the obtained myofibrillar protein with pepsin, and obtaining the antioxidant peptide through separation, purification and synthesis techniques. The antioxidant peptide of the present invention is a new type of antioxidant peptide, which has strong antioxidant activity after testing, and its iron ion reduction ability and oxygen free radical absorption ability are significantly higher than those of glutathione under the measurement conditions of the present invention , and at the same time, it has a significant inhibitory effect on the oxidative damage of NIH‑3T3 cells. The antioxidant peptide of the invention belongs to natural antioxidants, is safer to eat, and can be applied to antioxidant functional foods, health care products and medicines.
Owner:TIANJIN UNIV OF COMMERCE
Methods for boosting UVA photo-protection using antioxidants
ActiveUS10729633B2Boost UVA protectionImprove protectionCosmetic preparationsToilet preparationsOxygen radical absorbance capacityPhoto protection
Methods for providing broad spectrum photo protection to skin using antioxidants that provide UVA protection to skin are described. The methods include topically applying a cosmetic composition comprising: (a) at least one antioxidant having an Oxygen Radical Absorbance Capacity (ORAC) of at least 10,000 μmol TE / g and a Hydroxyl Radical Absorbance Capacity (HORAC) of at least 2,600 μmol GAE / g; (b) at least one organic UV filter; and (c) a cosmetically acceptable carrier; wherein the cosmetic composition provides an increase in UVAPPD PF of at least 30% relative to an otherwise identical cosmetic composition without the antioxidant(s) of (a). The disclosure also relates to the cosmetic compositions useful in the described methods.
Owner:LOREAL SA
A method for identifying the authenticity of propolis by combining fingerprint and antioxidant activity
The invention discloses a method for identifying the authenticity of propolis in combination with fingerprints and antioxidant activity, which belongs to the quality identification of propolis raw materials in the quality control category of raw materials for traditional Chinese medicine, and particularly relates to the combination of high-pressure liquid phase fingerprints and propolis' unique antioxidant properties. A method for identifying the authenticity of propolis raw materials and its products. The method includes three steps: fingerprint determination, oxygen free radical absorption capacity determination and sample identification. Several characteristic peaks in the fingerprints of the test samples are used to facilitate comparison and determine whether propolis is "true", "false" or "adulterated". At the same time, the propolis was identified as "true", "false" or "adulterated" by the definition of specific antioxidant index and fingerprint.
Owner:SHANGHAI JIAODA ONLLY CO LTD
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