Avian follistatin product

Abstract

Described herein are avian follistatin products, and methods for producing such products, in which such products are effective for a variety of conditions, including increasing muscle mass. Avian follistatin products described herein are packaged as dietary supplements or nutritional supplements are useful in muscle regeneration.

Description

RELATED APPLICATIONS [0001] This application claims the benefit of a provisional patent application filed on May 18, 2006, entitled “Fertilized egg protein powder (naturally occurring follistatin-based myostatin inhibitor produced in the form of a desiccated fertile egg protein powder for human or animal consumption) and naturally occurring follistatin extracted, isolated, and purified from fertile eggs.” This application also claims the benefit of Provisional Patent Application No. 60 / 895,405, filed Mar. 16, 2007, entitled “Process for the Preparation of Avian Follistatin Product.” The contents of these applications are incorporated by reference in their entirety.FIELD OF THE INVENTION [0002] Described herein are products containing follistatin, methods for preparing such products, methods for formulating such products and methods of using such products for the regulation of muscle growth. BACKGROUND OF THE INVENTION [0003] Wasting of skeletal muscle is a serious health condition t...

AI Technical Summary

Benefits of technology

[0010] In a further embodiment, the composition is used for at least one of the following purposes: athletic performance enhancement, as a protease inhibitor, to prevent muscle atrophy, for anti-aging purposes, as an HIV medication, for the treatment of Cushings disease, for the treatment of cachexia, for the prevention of muscle wasting, for the build-up of muscle mass; for the treatment of Addison's disease, muscular dystrophy, multiple sclerosis, type I diabetes, type II diabetes, rheumatoid arthritis, Crohn's disease, ulcerative colitis, irritable bowel syndrome, other autoimmune disorders, burns, joint injury, immobilization, coma, dislocations, gastrointestinal disorders, cancer, HIV, AIDS, sarcopenia, spinal cord damage, nerve damage, TGF alpha and beta disorders, ALS, vision disorders, weak muscles, ankolosing spondilitis, anorexia, bulimia, corticosteroid use, growth factor disorders, dysphasia, SIV, body dysmorphia, low androgen levels, menstruation problems, infertility, hypo- or hyper-thyroidism, catacholamine surge, low FSH, low LH, low GRH, low HCG, and viral infections; in conjunction with surgery and / or joint replacement operations; for the improvement of weight and / or muscle mass in livestock; to raise follistatin levels in a mammal (including a human); to lower myostatin levels in a mammaol (including a human); and combinations thereof.

Problems solved by technology

One of the most devastating but least-discussed aspects of age-related decline is the onset of frailty, i.e., the progressive loss of robustness in multiple tissues and organ systems.