71results about How to "Increase muscle mass" patented technology

An exercise system adapted to provide a truly interactive level of exercise with timed exercise intervals that are shown to be optimal in various physiological studies. An example of this invention provides the following unique features: (1) electronically controlled, continuously variable resistance in the positive stroke that responds to the user's efforts and varies the resistance according to the user's current physiological needs; (2) electronically controlled, continuously variable resistance force in the negative stroke that incrementally overcomes the positive muscle contraction and returns to the original position to complete each repetition; and (3) a sophisticated feedback control system that (a) monitors distance, time, and applied force by a user, (b) systematically controls the resistance force to complete each repetition in the specified time intervals, (c) maintains a smooth transition throughout the range of motion, and (d) virtually eliminates the variations of resistance caused by biomechanics, friction, inertia, etc. As a result, an example of the present invention provides the optimum in various types of exercise programs, including but not limited to (1) muscle building, (2) muscle toning, and (3) physical rehabilitation.

The invention provides methods of treatment that induce satiety in a subject for a period of at least around twenty-four hours by once-daily administration to the subject of a controlled release dosage form, wherein the dosage form is administered while the subject is in the fasted state and at a time of around six to around nine hours prior to the subject's next intended meal, and wherein the dosage form comprises a controlled release composition, which comprises an enterically-coated, ileum hormone-stimulating amount of a nutritional substance and releases the majority of the nutritional substance in vivo upon reaching the subject's ileum. The invention also provides a diagnostic tool for probing the health and disease state of the ileal hormones, excess or deficiencies. The invention provides a safe vehicle for targeted deliveries of chemical, pharmaceuticals, natural substances and nutrition to the ileum. The present invention also provides a method for treating noninsulin dependent diabetes mellitus, pre-diabetic symptoms, and insulin resistance, as well as a number of disease states and conditions including gastrointestinal disorders as otherwise described herein.

The present invention relates to a composition for reducing sport injury and promoting sport injury repair. The composition comprises the following raw materials and auxiliary materials, by weight, 500-2000 parts of hydrolyzed collagen protein, 100-400 parts of soybean protein peptide, 50-400 parts of chondroitin sulphate, 50-400 parts of glucosamine or a salt thereof, 100-1000 parts of a traditional Chinese medicine, 10-400 parts of haematococcus pluvialis, 1-100 parts of vitamin, and 1-100 parts of a mineral. The composition provides good effects for sport injury reduction and sport injury repair promotion.

The present invention relates generally to exercising equipment, and more particularly, to an improved multi-use weight lifting apparatus. The present weight lifting apparatus comprises a frame (12), a vertical guide member (52), at least one horizontal guide member (46), a weight bearing bar (60), and a safety catch mechanism (70). This weight lifting apparatus allows a weight lifter to perform exercise with vertical and horizontal ranges of motion that simulate the natural motions of using free weights while providing safety mechanisms that are not available with free weights.

The invention relates to an enhanced method of electrical muscle stimulation.

Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.

The present invention relates to therapeutic uses of ErbB ligands, including betacellulin. The therapeutic uses include methods of using ErbB ligand family compounds alone, or in conjunction with other agents, for reducing blood glucose levels, treating Type I and Type II diabetes, obesity, muscle wasting diseases, and cardiotoxicity.

The invention discloses a high-protein, low-sugar and high-lipid ketogenic meal replacement cake and a manufacturing method thereof. The formula comprises the following by mass parts: 16-35 parts of almond powder, 0-8 parts of flaxseed powder, 16-25 parts of protein powder, 10-25 parts of edible oil, 8-16 parts of dietary fiber, and 6-15 parts of erythritol. The formula of the invention is not only suitable for obese people and hyperglycemic people, but can also regulate the gastrointestinal health of the human body, and can increase the muscle mass of the body and improve the health of the user. Grease, erythritol and cream are mixed firstly, and then eggs and dietary fiber are added, and finally the mixed solid powdery material is added. The method can completely dissolve the dietary fiber, so that the produced cakes have delicate texture without obvious rough feelings.

The present invention provides a sports milk and its production method. Said invention uses the milk as carrier of nutrients, and uses serum protein to raise protein content, and adds the bio-active peptide and SOD so as to make the sports milk possess the functions of inhibiting blood lactic acid increment, raising immunity, preventing fatigue and hyperkinetic syndrome and promoting restoration after sports.

The invention provides an L-carnitine composition, an L-carnitine preparation and a preparation method and application thereof. The composition can comprise L-carnitine or a salt thereof acceptable pharmaceutically, kreatine, branched-chain amino acid, glutamine and soybean peptide. The composition used for improving tolerance can increase the combustion of fat in a human body, effectively oxidize the fat in the human body and decompose the fat into energy, implements nutrition required by the human body, and improves the athletic ability.

The invention belongs to the technical field of animal transgenosis, and discloses application of FHL3 gene in promotion of animal growth. The FHL3 gene is over-expressed in animal bodies, and the growth rate and muscle content of animals can be obviously improved. The invention firstly discloses that the over-expression of the FHL3 gene can promote the growth of individuals and the increase of the muscle content, and firstly discovers the function of the FHL3 gene in the aspect. The invention indicates that the FHL3 gene can serve as a candidate gene for preparing transgenosis livestock with high growth rate and high muscle yield.

The invention provides methods of treatment that induce satiety in a subject for a period of at least around twenty-four hours by once-daily administration to the subject of a controlled release dosage form, wherein the dosage form is administered while the subject is in the fasted state and at a time of around six to around nine hours prior to the subject's next intended meal, and wherein the dosage form comprises a controlled release composition, which comprises an enterically-coated, ileum hormone-stimulating amount of a nutritional substance and releases the majority of the nutritional substance in vivo upon reaching the subject's ileum. The invention also provides a diagnostic tool for probing the health and disease state of the ileal hormones, excess or deficiencies. The invention provides a safe vehicle for targeted deliveries of chemical, pharmaceuticals, natural substances and nutrition to the ileum. The present invention also provides a method for treating noninsulin dependent diabetes mellitus, pre-diabetic symptoms, and insulin resistance, as well as a number of disease states and conditions including gastrointestinal disorders as otherwise described herein.

The invention provides a chicken farm environment monitoring system which belongs to the field of environment monitoring. The system comprises a video acquisition module, a controller module, a sensor module, an environment control module, an alarm module, a wireless sending module, a wireless receiving module and a touch display module. The output ends of the video acquisition module and the sensor module are connected with the controller module. The input ends of the environment control module and the alarm module are connected with the controller module. The wireless sending module is connected with the controller module. The wireless sending module is wirelessly connected with the wireless receiving module. The wireless receiving module is connected with the touch display module. Through a temperature sensor, a humidity sensor, an oxygen sensor and an H2S sensor in the sensor module, the temperature, the humidity, the oxygen and the H2S content in a chicken house can be well acquired. The environment control module is used to manually change the chicken house environment to improve the environment quality of the chicken house. The problem that the existing chicken farm environment monitoring system cannot acquire environment data in real time is solved.

The invention discloses a mixed breeding method of rana nigromaculata and rice, and relates to the technical field of breeding. The method comprises the following steps: three parallel water ditches are dug in a paddy field with a length of 10 m and a width of 9 m along a length direction, distance between two adjacent water ditches is 3 m, a width of each water ditch is 1 m, a depth of each waterditch is 1.4-1.6 m, a length of each water ditch is 10 m, one rice area is arranged between two adjacent water ditches, the periphery of the paddy field is fenced by adopting a fence net, rice is planted in the rice areas, after the rice grow for 20 days, the young rana nigromaculata is stocked in the water ditches, a mixed solution of water and a tobacco stem extract liquid is sprayed to the rice every 8-10 days, and earthworms and fly maggots are thrown in the paddy field a next day after the tobacco stem extract liquid is sprayed every time. According to the mixed breeding method of the rana nigromaculata and the rice disclosed by the invention, in a mixed breeding manner of the rana nigromaculata and the rice, rice planting does not need pesticides to kill insects, the produced rice is green and pollution-free, and pests bred in the rice planting process provide a sufficient food source for breeding of the rana nigromaculata, so that the production costs are reduced.

The invention relates to the technical field of animal husbandry and in particular relates to forage feed for broiler chickens. The forage feed for the broiler chickens is prepared from the following components: 10 to 20 parts of chitosan, 20 to 40 parts of soybean meal, 20 to 40 parts of corn flour, 5 to 10 parts of calcium bicarbonate, 15 to 25 parts of locust powder, 5 to 10 parts of shell powder, 5 to 10 parts of seaweed meal, 1 to 3 parts of a compound amino acid, 2 to 6 parts of compound vitamin, 5 to 8 parts of tangerine peel, 20 to 40 parts of compound forage grass, 5 to 8 parts of traditional Chinese medicine additives and 1 to 3 parts of gravels. The forage feed for the broiler chickens has a reasonable ratio; the broiler chickens like eating the feed very much and the survival rate of the broiler chickens is greatly improved; the survival rate of the broiler chickens fed by the feed provided by the invention reaches up to 97.8 percent; the weight of the broiler chickens fed by the feed is 15 percent greater than that of broiler chickens fed by common feed; the meat quality is relatively delicious and has great chewiness.

The invention discloses a partial-base-deletion myostatin gene capable of being expressed in a cattle body, in particular to an MSTN mutant gene. The MSTN mutant gene is formed by knocking out severalbase sequences of a first intron of an MSTN gene. The MSTN mutant gene can promote the occurrence of a double-muscle phenomenon of a cattle skeletal muscle. The invention further discloses application of the MSTN mutant gene.

The invention relates to a comprehensive magneto therapy apparatus. A low-frequency sine wave alternating electromagnetic field is used to magnetize cells of a human body to enable the cells of the human body to obtain energy to activate the immune system and the self-repairing mechanism of the human body. Thereby, the invention provides the human kind with a novel method for non-medicinal illness treatment and healthcare. The comprehensive magneto therapy apparatus is formed by a main machine, a magnetic ring, a magnetic pad and an output cable. A control circuit board, a switch and a battery are installed in the main machine. An original sine wave DC / AC inverter is installed on the control circuit board and is used to invert the DC voltage of the battery into sine wave AC safety voltage. The waveform of the sine wave is fully consistent with the waveform of the sine wave of 220V mains supply voltage. Since the output cable is connected with the magnetic ring or the magnetic pad, alternating magnetic lines are generated in the magnetic coil of the magnetic ring or the magnetic pad and act on the human body to ensure relaxed and happy treatment and healthcare to the human body. The comprehensive magneto therapy apparatus can help people keep perennial youth and beauty; and the comprehensive magneto therapy apparatus is particularly suitable for travelers and families.

Provided herein are novel nucleic acid sequences, vectors comprising such nucleic acid sequences, host cells comprising such vectors, and transgenic animals comprising such nucleic acid sequences, and related molecules and methods relating thereto. Such novel nucleic acid sequences, vectors comprising such nucleic acid sequences, host cells comprising such vectors, and transgenic animals comprising such nucleic acid sequences, and related molecules and methods provide conditional overexpression of genes, such as myostatin, and transgenic animals conditionally overexpression genes, such as myostatin.

The invention discloses a zinc finger nuclease-mediated porcine MSTN (myostatin) gene mutation sequence and application thereof. By mediating the porcine MSTN gene by the zinc finger nuclease technique, base deletion is enabled, frameshift mutation is resulted in, early termination of translation is caused, an MSTN functional protein is unable to be formed, and the MSTN gene mutation sequence with 3782th to 3796th nucleotides deleted and 3800th nucleotide molecules mutated from T to G is acquired. Experiments show that a pig with the MSTN gene having the 3782th to 3796th nucleotides deleted and the 3800th nucleotide molecules mutated from T to G has evident double-muscled phenotype, both muscle content and lean percentage are evidently increased, and fat content is evidently lowered.

The present invention is the application of triterpenoid saponin as feed additive. Triterpenoid saponin is prepared through thrice alcohol extraction at normal temperature and the drying of the extracted liquid with the drying process being ether spray drying or vacuum drying. The present invention makes it possible to eliminate the residue of antiseptic in animal product, produce high-quality pollution-less animal product, and raise animal survival rate and feed utilization.

The invention discloses application of phytosterol ester in preparation of a mammal feed additive, and a method for promoting mammalian filial generation growth through maternal addition of phytosterol ester. According to the invention, the phytosterol ester replaces grease and is added into grease-free daily ration feed for mammals, so that the bile acid level in serum and amniotic fluid, the expression level of a placenta bile acid transporter and the expression level of an embryo posterior limb bud bile acid receptor can be reduced, and the weight, muscle content, gripping power, flatfish muscle fiber quantity, gastrocnemius muscle fiber cross sectional area and myosin heavy chain mRNA expression level can be improved. Besides, after entering the body of the mammal, the phytosterol ester is converted into phytosterol and fatty acid through the digestion effect of the small intestines, no toxic or side effect is generated, and therefore the phytosterol ester has wide application andpopularization value in the aspect of preparing mammal feed additives.

The invention discloses a partial base deletion muscle inhibin gene capable of being expressed in a mouse and application. An MSTN gene comprises two introns and three exon subsequence. 6 bases are deleted at the 175th-180th bit of the third exon are deleted, a cutting carrier containing partial base deletion muscle inhibin genes is constructed, a knock-out mouse containing the partial base deletion muscle inhibin genes is prepared, the cutting carrier containing the partial base deletion muscle inhibin genes is applied to MSTN organism character researches, the muscle amount of mouse skeletal muscle is increased, a double muscling phenomenon is generated, and the mouse basal metabolic rate and mouse body temperature are reduced. Through a genetic engineering method, base knock-out is performed on the original MSTN gene of the mouse, normal physiological functions of the organism are not affected while the muscle amount of the mouse skeletal muscle is increased, the muscle amount of the mouse can be quickly improved, and the partial base deletion muscle inhibin gene has large application prospect.

The invention discloses a meat duck complete feed capable of increasing the muscle content and reducing the sebum deposition. The meat duck complete feed comprises corns, wheat, bean meal, rice bran meal, cottonseed meal, wheat bran, soybean oil, sodium bicarbonate, edible salt, calcium hydrophosphate, calcium powder, lysine hydrochloride, methionine, choline, a trace element additive, composite vitamins, a mildew preventive, ethoxyquin, conjugated linoleic acid and L-carnitine. Compared with the prior art, the complete feed disclosed by the invention has the beneficial effects that (1) the experiment shows that the complete feed disclosed by the invention is particularly suitable for big meat ducks and can obviously increase the muscle content of the big meat ducks and reduce the sebum deposition of the big meat ducks; (2) compared with the conventional common meat duck complete feed, the meat duck complete feed disclosed by the invention has the protein level and energy level which are not obviously different; (3) the conjugated linoleic acid has a certain health-protection effect and is very beneficial to the health of the meat ducks; (4) the L-carnitine is very easily added into the feed; (5) batch production is easy to realize, and the meat duck complete feed is convenient to popularize.

A colostrum derived bioactive supplement derived of a number of cleaved protein fragments. The colostrum supplement is utilized with milk protein and Leucine to provide improved muscular function and exercise recovery.

The invention discloses a zinc finger nuclease mediated MSTN gene mutation sequence and application thereof. Base deletion is promoted by mediating porcine MSTN (myostatin) gene by virtue of a zinc finger nuclease technology to cause frameshift mutation, and as a result, MSTN functional protein is not formed since translation is terminated in advance; and meanwhile, a mutation sequence of the MSTN gene that nucleotides on 3781st-3791st sites are deleted is obtained. Tests prove that pigs of nucleotide deletion on 3781st-3791st sites in the MSTN gene have marked double-muscled phenotype as well as significant increase in both muscle content and lean percentage.

The present invention relates to methods for prevention and / or treatment of metabolic disorders, post-menopausal obesity and conditions associated with high fat diet consumption including, obesity, body weight gain, fat mass formation, bone mineral content reduction, white adipose tissue weight gain, increased cholesterol levels, increased leptin levels, insulin resistance, type II diabetes, increased blood glucose levels, inflammatory diseases, cardiovascular diseases, fatty liver condition (accumulation of fat in the liver), decreased uncoupling protein-1 (UCP-1) levels and increased lipogenesis.

The present invention provides a nutritional composition for improving a patient with heart failure; the nutritional composition is consisting of therapeutically effective high amounts of leucine and histidine. The present invention also provides the nutritional supplement comprising the nutritional composition, which may be a beverage product, a dietary supplement or food. The present invention further provides a method of using the nutritional supplement for treating patients with heart failure.

The invention discloses application of a nucleotide mixture in preparation of a preparation for preventing or relieving senile sarcopenia, and belongs to the field of medicine and health care. The nucleotide mixture consists of five kinds of 5'-mononucleotides or sodium salts thereof, and the mass ratios of CMP, AMP, UMP, GMP and IMP acid types converted by each kind of nucleotide are respectively as follows: 23-78% of CMP, 6-44% of AMP, 7-40% of UMP and 7-51% of GMP, and IMP is 0 or is greater than 0 but not greater than 2.5%. Nucleotide molecular weight is small, absorption is fast after the nucleotide mixture is taken by the human body, and bioavailability is high. The invention discovers that the intake nucleotide can improve the skeletal muscle function of the old body and increase the muscle mass by eliminating the mitochondrial dysfunction and reducing the oxidative stress so as to perform the functions of sarcopenia prevention and treatment, and a new way for preparing medicines or functional foods for preventing and treating the sarcopenia is provided.

The present invention relates to a diabetic shoe, and more specifically, to a customized shoe for preventing diabetes, preventing a diabetic foot due to complications of diabetes, and alleviating painfrom diabetic necrotic ulceration, wherein the shoe is produced by: attaching an insole to the upper surface of an outsole, wherein the insole has columns embedded with springs on the lower surface thereof and has acupressure bumps formed on the upper surfaces of the columns; attaching an inner sole formed of a shock absorbing material to the upper surface of the insole; placing a shoe upper integrated with a shock lining on the upper surface of the insole; and integrating with the outsole, the insole, the inner sole, and the shoe upper with the shock lining. Accordingly, the shoe can distribute the pressure from the sole of a foot; can protect the sole of the foot from impact; and by having an anti-deformation frame attached to the outer surface of the outsole, can prevent the shoe frombeing warped and deformed while increasing the weight of the shoe. \

The invention relates to application of pulsatilla saponin B4 in preparation of a medicine or health food for preventing, relieving or treating sarcopenia, and belongs to the technical field of food and medicine. The pulsatilla saponin B4 or the pharmaceutically acceptable salt thereof has the effect of preventing, relieving or treating sarcopenia, and can be used for preparing medicines or health-care foods for preventing, relieving or treating sarcopenia. The pulsatilla saponin B4 belongs to traditional Chinese medicines, and when the pulsatilla saponin B4 or pharmaceutically acceptable salts thereof are used for preparing medicines or health-care foods for preventing, relieving or treating sarcopenia, the pulsatilla saponin B4 has the advantages of mild and lasting effect and small side effect.