8results about How to "Increase muscle mass" patented technology

The invention relates to the field of biological pharmacy, and discloses a method for forming and transforming skeletal muscle fiber types by salvianic acid A sodium, which comprises the following steps: S1, small molecule drugs, S2, C2C12 cell culture and treatment, S3, mouse treatment, S4, measurement of grip strength and exercise tolerance, S5, evaluation of oxygen consumption, S6, RNA extraction and real-time fluorescent quantitative PCR (qPCR), S7, Westernblot, and S8, immunofluorescent staining. Sodium tanshinol adjusts expression of related genes of muscle fiber types, so that conversion of muscle fibers from glycolytic muscle fibers to oxidized muscle fibers is promoted, and understanding of sodium tanshinol on a molecular mechanism of muscle fiber type formation and conversion is deepened.

The present invention provides a skeletal muscle senescence delaying formula food for middle-aged and elderly people, the composition comprises lactoferrin and pyrroloquinoline quinone disodium salt, and the weight ratio of the lactoferrin to the pyrroloquinoline quinone disodium salt is 20: 1-30: 1. The composition can be applied to preparation of the middle-aged and elderly formula food for delaying skeletal muscle senescence, and the middle-aged and elderly formula food containing the composition has the effects of delaying skeletal muscle senescence and preventing sarcopenia, and remarkably improves muscle quality, muscle strength and muscle functions.

The invention discloses a crystal form A of acetyl L-carnitine hydrochloride, a preparation method of the crystal form A, and a bulk drug, a food additive, a feed additive and a composition containing the crystal form A. The crystal form A of the acetyl L-carnitine hydrochloride is good in solubility, high in stability, high in purity, regular in shape and suitable for being applied to bulk drugs, food additives and feed additives. The preparation method is simple in process, the crystal form A can be obtained at high yield through in-situ crystallization of a reaction solution and dispersion of ethanol, and the preparation method is suitable for large-scale industrial production.

The invention relates to a large-scale preparation method of a protamine oligopeptide-zinc-aquatic animal muscle hydrolysate compound. The preparation method comprises the following steps: by taking muscular tissues and mature testis tissues of aquatic animals as raw materials, respectively preparing an aquatic animal muscle hydrolysate and protamine oligopeptide; appropriate anion / cation exchange chromatography / resin purification is selected to obtain four aquatic animal muscle hydrolysates and protamine oligopeptides with higher key amino acid content; on the basis, the protamine oligopeptide-zinc-aquatic animal muscle hydrolysate compound which is good in antibacterial activity and higher in arginine and zinc element content and gives consideration to the content of four key amino acids is prepared through a two-step complexing process. The invention solves the problem that the peptide substances prepared by the previous patent technology always have anions which are harmful or useless to human bodies, and the prepared hydrolysate compound has high contents of peptide / amino acid and zinc which really exert functional activity.

The invention provides a children formula food for promoting skeletal muscle development, which comprises lactoferrin and pyrroloquinoline quinone disodium salt in a weight ratio of (20: 1)-(30: 1). The children formula food has the effect of promoting skeletal muscle development, ensures that children can fully absorb and utilize the key nutrients, and remarkably improves muscle quality, muscle strength and muscle functions.

The invention discloses a horse-derived anaerobic strain for improving athletic ability as well as a screening method and application thereof, and relates to the field of microorganisms. The invention discloses a horse-derived anaerobic strain capable of improving athletic ability, which is preserved in China General Microbiological Culture Collection Center, the preservation address is No.3, No.1 yard, Beichen West Road, Chaoyang District, Beijing, the preservation date is September 19, 2023, and the preservation number is CGMCC No.28469. The horse-derived anaerobic strain is classified and named as Enterococcus faecalis. The invention also discloses a screening method and application of the horse-derived anaerobic strain. The horse-derived anaerobic strain for improving the athletic ability, the screening method and the application have important guiding significance on development of probiotics of racing horses and additives of microbial feeds.

This invention discloses a strain of *Lactobacillus delbrueckii* with muscle-protecting function during fat loss, its products, and applications, belonging to the field of microbial technology. The invention discloses *Lactobacillus delbrueckii* subspecies Turb8, with accession number CGMCC No. 35627. This strain or its preparations can effectively prevent or improve muscle loss and functional decline during the use of fat-loss drugs such as GLP-1 receptor agonists (e.g., liraglutide, smegglutide), achieving the effect of "fat loss without muscle loss." While maintaining the original weight-loss effect of fat-loss drugs, the strain of this invention can significantly increase the user's lean body mass percentage, increase lower limb muscle mass, increase muscle fiber cross-sectional area, and improve muscle function indicators such as limb strength and suspension endurance. This invention also relates to bacterial agents containing this strain, various preparations, and their application in the preparation of products for improving (especially drug-induced) muscle loss.

The present invention relates to a composition for the purpose of preventing, alleviating, or treating a muscular disease, comprising an oxicam-based compound, wherein the composition strengthens muscles and increases muscle mass through the effects of promoting differentiation of myoblasts and increasing muscle fibers, and can, thereby, have a treatment effect for various muscular diseases and have muscle strengthening or motor performance increasing effects.