248 results about "Muscle functions" patented technology

Systems and methods for enhanced implantation of an electrode lead for neuromuscular electrical stimulation of tissue associated with control of the lumbar spine for treatment of back pain, in a midline-to-lateral manner are provided. The implanted lead may be secured within the patient and used to restore muscle function of local segmental muscles associated with the lumbar spine stabilization system without disruption of the electrode lead post-implantation due to anatomical structures.

The invention discloses a multi-freedom wearable robot for hand function recovery. The robot comprises mechanical arms and mechanical fingers; the mechanical fingers consist of a mechanical thumb, a forefinger, a middle finger, a ring finger and a little finger, wherein the forefinger, the middle finger, the ring finger and the little finger have the same structure as that of the thumb; the mechanical forefinger mainly comprises air muscle, a finger end bracket, a first middle connecting piece, a finger front end bracket and a second middle connecting piece which are connected in turn through a connecting rod; the air muscle drives the second middle connecting piece to move through a rigid string so that the finger of a patient makes lituate and adduction exercises; the inside of each connecting piece is provided with a pressure spring; and inside walls of the two connecting pieces are distributed with rolling beads to reduce friction between the connecting rod and the connecting pieces. The invention also provides a control system and an integrated electricity stimulation system of the robot to assist a patient to rebuild muscle function. The robot provides an assisted exercise mechanism for the fingers, has multiple freedom degrees and dimension adjustable movement mechanism, and can effectively assist the patient to finish repeated training of composite exercise for fingers and complicated finger dividing exercise.

The disclosure provides methods for treating neuromuscular disorders in mammals. The disclosed methods include administering therapeutically effective amounts of a GDF-8 inhibitor and a corticosteroid to a subject susceptible to, or having, a neuromuscular disorder, so as to maintain desirable levels of muscle function.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include electrodes coupled to an implantable pulse generator (IPG), a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

The present invention relates to a device and system to measure and assess superficial skeletal muscle mechanical and neuromuscular contractile characteristics, and interpret the results to provide metrics with quantifiable and qualitative descriptors relating to muscle function. The present device provides a further type of mechanomyography and a new use for acceleromyography by measuring the mechanical muscle movement of an involuntary stimulated muscle from an automated electro-stimulation protocol to determine muscle contractile properties. Muscle twitch response during the latent, contraction and relaxation phase is measured using an array of multiple accelerometers on a sensor pad to assess and diagnose muscle. function from various measurements. This information is processed using algorithms to determine muscle function abnormalities, muscle activation patterns, muscle symmetry of lateral muscle pairs, muscle synchronization of antagonist muscle, muscle force, muscle acceleration, muscle speed, muscle tone, muscle fatigue, muscle power / torque and muscle efficiency.

A system of implanting electrode leads for restoring muscle function to the lumbar spine to treat low back pain is provided. The system provides efficient implantation of the leads, including the ability to verify deployment of anchoring mechanisms on the lead using an impedance assessment, such that the implanted lead may be secured within the patient and used to restore muscle function of local segmental muscles associated with the lumbar spine stabilization system.

Muscle function can be augmented by causing interconnected electrically operated actuators on an external surface of a muscle or organ to compress or contract. The actuators can be arranged in a band, mesh, or other suitable arrangement.

A lower extremity orthosis is configured to be coupled to across at least one joint of a person for gait assistance and can incorporate knee, thigh, hip and ankle / foot assistive orthotic devices which can be used in various combinations to aid in the rehabilitation and restoration of muscular function in patients with impaired muscular function or control.

The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.

The invention provides an upper limb rehabilitation system and method based on a myoelectric signal and a virtual reality interaction technology. The system comprises a myoelectric signal acquiring and processing part, a virtual reality man-machine interaction part and a muscle function evaluation part, wherein the myoelectric signal acquiring and processing part is composed of a data acquiring module, a signal processing module and a model control module; the virtual reality man-machine interaction part is composed of an upper computer virtual environment module and a force feedback device module; the muscle function evaluation part is composed of a muscular tension quantitative evaluation module and a muscle cooperativeness quantitative evaluation module. According to the rehabilitation method, myoelectric control is used so that a patient subjective intention can be reflected better; a patient keeps initiative in a rehabilitation process by using a virtual reality technology, and the portability, the safety and the effectiveness of rehabilitation trainings are improved. According to the upper limb rehabilitation system and method, an existing clinical rehabilitation evaluation manner can be combined and a muscle function state of the patient is objectively evaluated, so that rehabilitation training standards are provided for the patient and evidences for formulating a therapeutic scheme are provided for rehabilitation doctors.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include electrodes coupled to an implantable pulse generator (IPG), a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

The invention provides a self-adaptive recommendation method and system for a rehabilitation training prescription based on deep reinforcement learning. The method comprises the following steps: 1) collecting basic information and medical record information of a patient; 2) acquiring cerebral cortex blood oxygen data of different brain regions of the patient and movement and myoelectricity data ofaffected limbs of the patient; 3) calculating brain function evaluation indexes during exercise and rehabilitation training of the patient by utilizing the brain blood oxygen data, and calculating exercise function evaluation indexes and muscle function evaluation indexes during exercise and rehabilitation training of the patient by utilizing the exercise data and the myoelectricity data so as todynamically evaluate the brain function, the exercise function and the muscle function of the patient; 4) inputting the brain function, motion function and muscle function evaluation indexes obtainedin the step 3) into a pre-established deep reinforcement learning model to train the deep reinforcement learning model and automatically generate a rehabilitation training prescription; and 5) feeding back the rehabilitation training prescription generated in the step 4) to a doctor and the patient for rehabilitation training. By means of the method and system, self-adaptive adjustment of the training prescription can be achieved.

The invention provide an intelligent electric wheelchair, comprising sensor chips, handles, a foot training device, fixing plates, a back massage plate device, a touch control device, a seat, a leg massage device, a telescoping device, a connecting cross rod, a fixing frame, universal wheels, and a base. The back massage device is internally provided with a sitting posture adjusting module. The foot training device is internally provided with a virtual reality rehabilitation system, comprising a force signal acquisition and processing portion, a virtual reality man-machine interaction portion, and a muscle function evaluation portion. The touch control device is internally provided with an intelligent navigation system. The wheelchair can massage acupoints, and the virtual rehabilitation system improves interestingness of rehabilitation. The muscle function evaluation portion can realize evaluation of muscle rehabilitation effect. A voice identification module and a mobile phone APP terminal unit realize voice control of a mobile phone, so both hands are liberated, and use is more convenient. The intelligent navigation system can complete intelligent navigation, and the system is simple in operation and high in intelligent degree.

An adjustable orthotic insole and a unique method of implementation has a shell and a sole lifter that is to correct malalignment of lower extremities and other functions such as cushioning, massage, etc are not anticipated. The distribution of ground reaction force is changed due to the orthotic effect of the sole lifter. A user adjusts position and thickness of the sole lifter incessantly until malalignment of lower extremities is restored to optimal alignment symmetrically. The present invention employs a unique method that the sole lifter is always opposite to rear foot lifter. Once the malalignment of lower extremities is corrected by the orthotic insole, the user would be able to maintain good posture and ambulate in ideal gait. Therefore, symmetric and coordinated movements are harmonious with balanced muscle function. The musculoskeletal system would be protected from overuse injury.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include electrodes coupled to an implantable pulse generator (IPG), a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

Described herein are compositions and methods for treating and / or preventing disorders affecting skeletal muscular function that are caused by reactive oxygen species in mammals. More specifically, the disclosure relates to the treatment and / or prevention of disorders affecting skeletal muscular function through the administration of histamine and histamine-related compounds.

The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.

The disclosure provides methods for treating neuromuscular disorders in mammals. The disclosed methods include administering therapeutically effective amounts of a GDF-8 inhibitor and a corticosteroid to a subject susceptible to, or having, a neuromuscular disorder, so as to maintain desirable levels of muscle function.

Some embodiments of the present invention provide systems and methods for treating diminished muscle function. Some systems include an electrical member that delivers electrical energy to a hand region of a body that comprises a dysfunctional muscle; a joint motion assembly that couples to the body and provides, to a joint adjacent the dysfunctional muscle, a motion made up of a cycle of opposing joint movements; and a control unit that provides an operator of the system with control of a timing of electrical energy delivery and an amount of electrical energy delivered. Some systems time the electrical energy delivery to occur when the moving joint is near an inflection point and deliver electrical energy delivered in amounts effective to result in a depolarization of the dysfunctional muscle, a nerve in proximity of the joint, and / or a muscle of substantially normal function in proximity of the joint.

An apparatus and process for measuring the motion of internal joint structures during and for measuring the function of muscles involved with the motion of a joint of a subject are disclosed. The apparatus can be configured in three forms: a horizontal, vertical, or butterfly motion control device. Each configuration comprises a static member and a moving member, in which the moving member operates to move or be moved by the subject being studied. Also disclosed are processes for using each apparatus to measure of the relative motion of a skeletal structures in a subject, in which the subject is positioned in the apparatus and commanded to move while diagnostic medical images are taken or captured. Additionally, processes for using each apparatus to specifically measure and collect data on the function of the subject's muscles are disclosed.

The present invention provides an apparatus and method for monitoring muscle function based on an index derived from a pressure or force signal. The muscle function index is derived from an instantaneous muscle stiffness ratio computed as the ratio of the first time derivative of the pressure or force waveform to the corresponding instantaneous pressure or force. The instantaneous stiffness ratio, {dot over (E)} / E(t), is in units of 1 / sec and relates to the rate of strong bond formation and will be influenced by calcium handling properties of the muscle fibers and the intracellular calcium concentration. As such, an index derived from {dot over (E)} / E(t) provides a measure of the inotropic status of the muscle.

Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include one or more electrode leads coupled to an implantable pulse generator (IPG) and a tunneler system for subcutaneously implanting a proximal portion of the lead(s). The system may also include a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

The present invention encompasses combination comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and / or muscle function.

An isolation exercise machine comprises two force stations and a connection mechanism that causes the force stations to rotate in opposite directions in response to applying forces to the force stations. The forces overcome first loads due to weights placed on exercise arms to which the force stations are joined. The force stations are located relative to a support that enables a person on the support to exercise selected pairs of muscles. A leverage arm is attached to the connection mechanism for rotating with one or the other force station. At the end of a concentric muscle function, a spotter applies a small force to the leverage arm. The applied force is converted by the connection mechanism into second loads at the force stations that the person resists during an eccentric muscle function. A counterweight arm and counterweight may be used to cancel out the weight of the leverage arm.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include one or more electrode leads coupled to an implantable pulse generator (IPG) and a tunneler system for subcutaneously implanting a proximal portion of the lead(s). The system may also include a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

The present invention relates to humanised antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such humanised antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function.