145 results about "Joint injury" patented technology

The invention provides methods for treating post-surgical articular or incisional pain and/or discomfort in a patient. The invention further provides improved surgical methods and controlled release formulations for treating an articular injury of a joint in a patient, in which a collagen formulation is used in conjunction with a surgical procedure to treat the articular injury or the side effects of the surgical procedure. Collagen formulations of the invention and their use, in addition to the surgical procedure, may provide at least one or more of the following benefits: reduced patient pain, shortened recovery time and/or improved joint condition (including treatment of the underlying articular injury). Moreover, the methods and compositions of the invention can be used in conjunction with essentially any surgical procedure used to treat an articular injury. The invention further provides compositions and methods for treating post-surgical articular or incisional pain in a patient as well as a catheter for use in the methods of the invention.

The present invention provides a differential pressure body suit with external support against body suit migration. In its preferred embodiment, such body suit may comprise a close-fitting, multi-layered suit sealed against a mammal's skin to contain the differential pressure, or a looser-fitting suit that bends at the mammal's joints with minimal force. External support means include either fixed or movable mechanical supports attached to the body suit, extraordinary air pressure levels for making the body suit rigid, or exoskeletons attached to the body suit. A cyclic control system can turn the differential pressure condition within the body suit on and off on a selective basis to accommodate the movement of the legs of the mammal. This differential pressure body suit provides a portable and convenient system for, e.g., rehabilitating a skeletal joint injury or training the mammal for injury prevention or athletic performance. The pressurization reduces the weight of the body to greater or lesser extents, and offloads the weight to the ground through the external support means.

The invention provides viscosupplementation methods for treating osteoarthritis and joint injury with HA-based viscosupplements, particularly viscosupplements with an intra-articular residence half-life shorter than 3 weeks. Viscosupplements for use in the methods of the invention may be further characterized in that they contain less than 20 mg/ml HA, at least 5% (w/w) of which is in a gel form, such as, e.g., hylan B. In an illustrative embodiment, hylan G-F 20 (Synvisc®) is administered in a single intra-articular knee injection of 6±2 ml.

The present invention provides a composition, and a method of use thereof for treating connective tissue damage in man and in animals, which comprises a therapeutically effective amount of chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan (hyaluronic acid). Particularly, the present invention provides a composition, and a method of use thereof, for treating connective tissue damage including, but not limited to, arthritic disease, osteoarthritis, rheumatoid arthritis, osterochondrosis dessicans, cartilage damage, joint injury, joint inflammation, joint synovitis, degenerative joint disease (DJD), post surgical DJD, traumatic injury, fracture, tendon damage, ligament damage, skeletal damage, musculoskeletal damage, fiber damage, adipose tissue damage, blood cell damage, and plasma damage. Compositions for delivery of the present invention include those for parenteral, oral, and transmucosal delivery and for direct surgical placement onto the affected tissues.

The invention provides an ankle joint rehabilitation training device, which comprises a support platform, a first rotating platform, a first driver, a second rotating platform and a second driver, wherein two support pillars are oppositely arranged on the support platform, the first rotating platform is in a frame structure, the two opposite outer sides of the first rotating platform are respectively provided with a first support frame, and the two first support frames and the two support pillars are correspondingly movably matched, so that the first rotating platform can be rotated on a horizontal plane. The first driver is connected with the first rotating platform to drive the first rotating platform to rotate around a first horizontal shaft. The second rotating platform is provided with a footed tray which is rotatably arranged in the first rotating platform around a second horizontal shaft which is perpendicular to the first horizontal shaft. The second driver is connected with the second rotating platform to drive the second rotating platform to rotate around the second horizontal shaft. The ankle joint rehabilitation training device has a simple integral structure, is suitable for the rehabilitation therapy of a patient with ankle joint injury and the measurement of human balance capacity.

A solid implantable bone construct (12) shaped like a cylinder, a cone, or a frustum, for anchoring ligament implants. The bone construct (12) can include a bone component and a biocompatible solid component. The bone component can include particulate bone of between 75 and 600 microns, powdered bone of 75 microns or smaller in size, or both. The biocompatible solid component can include calcium sulfate hemihydrate, a calcium phosphate product, or both. The bone component can be between 5 and 50 wt-% of the construct (12) and the biocompatible solid component can be at least 50 wt-% of the construct (12). Also disclosed is a composite graft (10) comprising a first bone dowel (12) and a ligament (20) and a method of securing one bone to another using the composite graft (10).

A traction type ankle joint rehabilitation training device comprises a base, a wheel support, an air pressure lifting table, a shank support, a foot cover, a motor driving mechanism and a flexion andextension traction mechanism. The wheel support is arranged at one end of the base, and the air pressure lifting table is installed in the middle of the base; the motor driving mechanism is installedon one side of the base, and the flexion and extension traction mechanism is arranged among the motor driving mechanism, the wheel support and the foot cover; the shank support is movably connected tothe air pressure lifting table; the foot cover is provided with an upper hook and a lower hook, the upper hook and the lower hook are connected with the motor driving mechanism through the flexion and extension traction mechanism separately, the air pressure lifting table drives the lower leg support to ascend and descend, and the motor driving mechanism drives the foot cover to achieve flexion and extension through the flexion and extension traction mechanism. A traction rope is connected with a motor, the traction rope is connected with the foot cover to drive the ankle joint to achieve flexion, extension or turning-over, a patient with ankle joint injuries can be effectively assisted in post-operation rehabilitation training, or a patient suffering from ankle joint deformity can be subjected to corrective treatment. The traction type ankle joint rehabilitation training device is simple in structure and convenient to operate.

The present invention provides a differential pressure body suit with external support against body suit migration. In its preferred embodiment, such body suit may comprise a close-fitting, multi-layered suit sealed against a mammal's skin to contain the differential pressure, or a looser-fitting suit that bends at the mammal's joints with minimal force. External support means include either fixed or movable mechanical supports attached to the body suit, extraordinary air pressure levels for making the body suit rigid, or exoskeletons attached to the body suit, or a counter-force suspension cable adjustment system. A cyclic control system can turn the differential pressure condition within the body suit on and off on a selective basis to accommodate the movement of the legs of the mammal. This differential pressure body suit provides a portable and convenient system for, e.g., rehabilitating a skeletal joint injury or training the mammal for injury prevention or athletic performance or fat burning. The pressurization reduces the weight of the body to greater or lesser extents, and offloads the weight to the ground through the external support means.

The present invention relates to methods and devices for minimally invasive diagnosis and treatment of joint injuries. Small diameter endoscopic devices are used for visualization and second part is used to provide access for the insertion of small diameter surgical tools without the use of distending fluid. Preferred embodiments of the endoscopic devices can utilize wireless transmission to a handheld display device to visualize diagnostic and therapeutic procedures in accordance with the invention.

The present invention provides a differential pressure body suit with external support against body suit migration. In its preferred embodiment, such body suit may comprise a close-fitting, multi-layered suit sealed against a mammal's skin to contain the differential pressure, or a looser-fitting suit that bends at the mammal's joints with minimal force. External support means include either fixed or movable mechanical supports attached to the body suit, extraordinary air pressure levels for making the body suit rigid, or exoskeletons attached to the body suit, or a counter-force suspension cable adjustment system. A cyclic control system can turn the differential pressure condition within the body suit on and off on a selective basis to accommodate the movement of the legs of the mammal. This differential pressure body suit provides a portable and convenient system for, e.g., rehabilitating a skeletal joint injury or training the mammal for injury prevention or athletic performance or fat burning. The pressurization reduces the weight of the body to greater or lesser extents, and offloads the weight to the ground through the external support means.

The invention discloses a compound preparation used for joint care and a preparation method thereof. The compound preparation comprises active ingredients and auxiliary materials, wherein the active ingredients comprise glucosamine, chondroitin sulfate, dimethyl sulfone and collagen, and the glucosamine is glucosamine sulfate or glucosamine hydrochloride or glucosamine phosphate or mixture of theglucosamine sulfate and the glucosamine hydrochloride and the glucosamine phosphate; and the auxiliary materials comprise excipient, disintegrant, lubricant, bonding agent and wetting agent. The invention has better treatment and prevention functions on arthritis and joint injury; the prepared tablet has good disintegration property, rapid digestion, quick effect taking, strengthened stability andhigh absorption and utilization ratio; and the consumption of the raw materials and the auxiliary materials achieves the optimal proportion.

The present invention relates to methods and devices for minimally invasive diagnosis and treatment of joint injuries and other injuries or diseases in body joints, tissues, and cavities. Small diameter endoscopic devices are used for visualization and to provide access for the insertion of small diameter surgical tools without the use of distending fluid. Preferred embodiments of the endoscopic devices can utilize wireless transmission to a handheld display device to visualize diagnostic and therapeutic procedures in accordance with the invention.

The invention discloses an ankle and foot orthopedic device and a method for controlling the same, and belongs to the technical field of medical apparatus and instruments. The ankle and foot orthopedic device and the method have the advantages that pressure sensors, an EMG (electromyography) sensor and a multi-dimensional gyroscope acceleration sensor are combined with one another and are appliedto controlling an ankle and foot orthopedic apparatus, accordingly, plantar pressure distribution data, muscle surface bioelectricity, gesture data and acceleration a wearer is in different movement modes can be effectively acquired, and reliable parameters can be provided to accurate control; the ankle and foot orthopedic device can assist in training rehabilitation and correction on ankle jointcontrol disabilities who are achilles tendon rupture postoperative recovery, talipes equinus, stroke, ankle joint injury and hemiplegia patients and the like, can adapt to characteristics of actions such as slow walking, fast walking, receding, stair ascending, stair descending, turning and the like of the ankle joint control disabilities, and has gait correcting and walking assisting functions.

The present invention provides for methods and compositions for treating or preventing arthritis and joint injury.

The present disclosure provides biomaterials and methods for preventing and minimizing progression of cartilage and/or connective tissue damage. Also provided herein are biomaterials and methods for alleviating and/or reducing the risk for developing arthritis (e.g., osteoarthritis) associated with joint injury and/or joint surgery.

The invention discloses a method and device for arthroscopically measuring an intra-articular structure. The method comprises the following steps of obtaining a target image with an arthroscope reaching inside a joint when triggering operation on image shooting is detected, wherein the target image comprises an intra-articular lesion or defect site and a measuring scale which is arranged nearby the intra-articular lesion or defect site; displaying the target image; calculating a display scale of the target image according to an pixel distance indicated in the target image with the measuring scale and an actual distance indicated with the measuring scale; determining a contour line of the intra-articular lesion or defect site according to point tracing operation on the profile of the intra-articular lesion or defect site; calculating the actual distance between any two points on the contour line of the intra-articular lesion or defect site and/or the area of the intra-articular lesion or defect site according to the contour line of the intra-articular lesion or defect site and the display scale. For a joint injury in an irregular shape, the method enables a graft to be matched with the joint injury accurately.

The invention discloses a portable refrigerating device and a portable medical cold compress device. The portable refrigerating device comprises a portable box body, a refrigerating containing cavity formed in the box body and used for containing goods needing to be refrigerated, a refrigerating system, a control system, a rechargeable battery arranged in the box body, connected with the refrigerating system and the control system and used for providing power, and a charging interface connected with the rechargeable battery. The portable refrigerating device and the portable medical cold compress device are small in size and convenient to carry, cold drinks can be provided conveniently through the portable refrigerating device, due to the fact that an intermittent cold compress system meeting the requirement for joint injury treatment is adopted for the portable medical cold compress device, timely intermittent cold compress can be conducted on an injured part, and the cold compress effect is greatly improved. The intermittent cold compress system comprises three bandages used for different cold compress parts, free conversion can be conducted as needed in the use process, and flexibility and convenience are achieved.

The invention discloses infantile convulsions tincture for dredging channels and expelling wind-damp. The specific formula consists of 0.05 g of dried bee venom, 5 g of propolis, 15 g of natural Chinese herbal medicine-radix clematidis, 5 g of flowers carthami, 5 g of pseudo-ginseng, 15 g of lycopodium clavatum, 10 g of sappanwood, 8 g of radix curcumae longae, 15 g of angelica sinensis, 5 g of sangusis draconis and 2 g of borneol; coarse powder is prepared, is dipped in 60 degrees of white spirit for termly stirring, and is then stood; supernate is poured out for future use; medical alcohol is added in remainder precipitates for stirring and standing; the supernate is poured out; the supernate collected by the two times is mixed, and is filtered by a nylon yarn for preparing the tincture; the tincture is filled in a watering can for future use. The infantile convulsions tincture for dredging channels and expelling wind-damp has no toxic and side effects on human bodies, makes up one blank of external tincture, has the functions of relaxing muscles, stimulating blood circulation, dredging channels and dispersing blood stasis, has excellent effect on the external use of itching kind skin diseases, has simple preparation process, and has excellent curative effect on joint injury, women dysmenorrheal, nerve headache, limbs chills, cat fever, abnormal skin color, waist pain and children fever.

The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions related to joint damage, including acute joint injury and arthritis.

Described herein are methods for using bone morphogenetic proteins (BMPs), such as OP-1 (also known as BMP-7), to treat pain caused by osteoarthritis. The methods involve administering to a patient suffering from pain caused by osteoarthritis a BMP, for example, intraarticularly by injection directly into the joint afflicted with osteoarthritis. The methods of the invention provide long-term pain relief to sufferers of osteoarthritis and can improve the functionality of the joint to which the BMP is administered.

The invention relates to an artificial joint prosthesis with a partial gradient pore structure and a preparation method thereof, and belongs to the biomedical engineering field. The prosthesis comprises a prosthesis handle and a gradient pore structure body; the gradient pore structure body is welded on a presetting position of the prosthesis handle; the gradient pore structure body comprises a metal titanium plate, a first metal titanium ball, a second metal titanium ball, and a third metal titanium ball; the sizes of the first metal titanium ball, the second metal titanium ball and the third metal titanium ball become larger, and the three metal titanium balls are sintered on the metal titanium plate. The method sinters spherical metal powders on the metal titanium plate in a layered way through the sintering process to gain the gradient pore structure body which is then welded on the presetting position of the joint prosthesis. The artificial joint prosthesis not only prevents the prosthesis handle from high-temperature heat treatment process, keeps good high-strength mechanical property, but also gains proper gradient pore structure, provides space to cell and tissues for the long-term embedding, promotes the ankylosing between new formed bone tissues and host bones, and realizes the biological fixation of the prosthesis; in addition, the artificial joint prosthesis can be applied to the restoration of joint injuries in clinic.

The present invention provides a composition, and a method of use thereof for treating connective tissue damage in man and in animals, which comprises a therapeutically effective amount of chondroitin sulfate, N-acetyl D-glucosamine, and hyaluronan (hyaluronic acid). Particularly, the present invention provides a composition, and a method of use thereof, for treating connective tissue damage including, but not limited to, arthritic disease, osteoarthritis, rheumatoid arthritis, osterochondrosis dessicans, cartilage damage, joint injury, joint inflammation, joint synovitis, degenerative joint disease (DJD), post surgical DJD, traumatic injury, fracture, tendon damage, ligament damage, skeletal damage, musculoskeletal damage, fiber damage, adipose tissue damage, blood cell damage, and plasma damage. Compositions for delivery of the present invention include those for parenteral, oral, and transmucosal delivery and for direct surgical placement onto the affected tissues.

The invention relates to the application of ginkgolic acid in treating arthritis. The ginkgolic acid comprises ginkgoic acid, ginkgol, ginkgoic diphenol and the like and can be obtained from the extracts of the parts of the leaves, the fruits, the episperms, the rhizomes and the like of gingkoes by a chemical separation method. The arthritis is rheumatoid arthritis, chronic infectious arthritis, gouty arthritis, osteoarthritis and the like. A medicine, a medical appliance or a disinfector preparation which contains the ginkgolic acid and is used for treating the arthritis contains 0.001 to 80 percent of ginkgolic acid (calculated according to weight percent) and an external preparation substrate or an acceptable carrier which is generally used pharmaceutically; and the preparation is any external preparation formulation which is given pharmaceutically. The research of a pharmacological experiment shows that the ginkgolic acid has the favorable actions of improving arthrocele, relieving joint injury and suppressing local inflammation to an animal model with the arthritis. Clinical trial shows that the ginkgolic acid has an obvious therapeutic action to each type of arthritis, and the effective rate reaches more than 90 percent. In use, the ginkgolic acid is safe and has no side effect.