37 results about "VASCULAR EMBOLISM" patented technology

The invention relates to the technical field of clinical auxiliary decision making, in particular to a vascular embolism clinical risk prognosis evaluation system based on multi-source data. The system comprises a patient multi-source data acquisition module, a clinical data feature processing module, a multi-source data fusion module and a clinical explanatory enhancement module. The method comprises the following steps: acquiring basic information, clinical examination results, vital signs and medical image data of a patient, and respectively performing structured and image feature extraction to form multi-modal feature representation; a key area is mined in combination with a self-attention mechanism, and the feature expression ability is improved; and through comparison of historical similar cases and contribution analysis of local features, interpretability enhancement of model output is realized, and an embolism risk prediction result with a clinical reference value is generated. The method effectively improves the prediction accuracy, stability and medical readability of the model, and is suitable for auxiliary diagnosis and treatment scenes of diseases such as vascular embolism.

The invention relates to the technical field of medical artificial intelligence, in particular to a vascular embolism risk prediction method based on big data analysis, and the method comprises the steps: collecting a pulse pressure fluctuation rate, a microcirculation resistance index and a platelet adhesion gradient through a multi-source sensor, and extracting dynamic physiological parameter time sequence features; constructing a hemodynamic finite element model based on CTA and VFI image data, and obtaining a vascular mechanical feature vector; deep coupling of the pulse pressure spectrum and the circumferential stress is achieved through dynamic time warping and convolution mapping, and a multi-modal risk feature set is generated; and performing cross-modal coding by using the double-branch graph neural network, and outputting an acute embolism probability and a three-dimensional risk thermodynamic diagram. According to the method, physiological, image and mechanical multi-dimensional information is fused, and the method has the advantages of being high in real-time performance, accurate in positioning and good in interpretability and is suitable for risk prediction and auxiliary diagnosis of clinical cardiovascular and cerebrovascular events.

The invention discloses a balloon catheter pressure applying device for thrombus treatment and vascular embolism, and relates to the technical field of medical instruments, the balloon catheter pressure applying device comprises a first catheter, the first catheter is sleeved with a second catheter, the front end of the second catheter is fixedly connected with a memory metal net bag, the second catheter is sleeved with a third catheter, and the third catheter is fixedly connected with a memory metal net bag. A fourth catheter is fixedly connected to the outer side of the third catheter, a rear balloon is fixedly connected to the outer side of the front end of the air delivery pipe, an exhaust head is fixedly connected to the front end of the first catheter, a front balloon is fixedly connected to the outer side of the exhaust head, and a thrombus removing assembly used for assisting in removing thrombus is arranged on the outer side of the front end of the first catheter. According to the thrombus treatment vascular embolism balloon catheter, the thrombus dissolving medicine in the medicine storage balloon membrane is squeezed out through the pressure applying device, the thrombus dissolving medicine can penetrate through the memory metal net bag to move to the embolism position, thrombus is dissolved, and the thrombus can be better removed through cooperation with the thrombus removing assembly.

The invention relates to the technical field of traditional Chinese medicine health-care products, and particularly discloses an earthworm protein peptide composition for improving vascular embolism and a preparation method thereof.The earthworm protein peptide composition is prepared from, by weight, 28-34 parts of earthworm protein peptide, 20-26 parts of active pharmaceutical ingredients, 1-5 parts of ginkgo biloba extract, 12-15 parts of corn oligopeptide powder and 4-8 parts of auxiliary materials; lumbricus protein peptide, active pharmaceutical ingredients, ginkgo biloba extract and corn oligopeptide powder are used as raw materials, a solubilizing component is added in the preparation process, the solubilizing component is prepared by mixing functional extract, nattokinase and tween-80 according to a certain proportion, the functional extract is prepared by coating grape seed extract with hydroxypropyl-beta-cyclodextrin, and the solubilizing component is prepared by mixing the functional extract, the nattokinase and the tween-80 according to a certain proportion. Through the synergistic effect of the components, the antithrombotic effect of the earthworm protein peptide composition is synergistically enhanced.

The invention belongs to the field of medical devices, and particularly relates to a soft robot thrombus removing device which comprises a robot body, a minimally invasive thrombus taking head, an external magnetic field control device and an imaging display device. The minimally invasive thrombectomy head comprises a front section thrombectomy part, a middle section positioning part and a tail section control part; a plurality of through hole structures are arranged in the thrombus extraction component; a rotating structure, a suction component and a clamping structure are respectively arranged in a plurality of through hole structures arranged in the thrombus extraction component; a magnetic navigation sensor is arranged in a middle section positioning component of the minimally invasive thrombus extraction head; a control unit electrically connected with the rotating structure, the suction part and the clamping structure is arranged in the control part at the tail section of the minimally invasive thrombus extraction head; the robot body is transported to the position close to the diseased region through the catheter and the puncture needle sheath. The device has the advantages that the device is specially designed for treating vascular embolism, is particularly suitable for removing thrombus of small blood vessels such as cerebral vessels, and has extremely high flexibility and operation precision.

The systems and methods of the present invention can remove target material (including blood clots) from body parts (including but not limited to the circulatory system) for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebral vascular embolism, and other vascular obstructions. The capture system may include a tubular body and an end having an opening and a capture guide. In some embodiments, the body or funnel tip of the catheter is expandable.

The invention relates to hydrogel for promoting healing of diabetic wounds as well as a preparation method and application of the hydrogel, and belongs to the technical field of hydrogel dressings. The invention discloses an exosome hydrogel, which is characterized in that exosome is loaded in crosslinked aldehyde hyaluronic acid and carboxymethyl chitosan, the aldehyde hyaluronic acid is grafted with L-arginine, and the exosome is derived from bone marrow mesenchymal stem cells. L-arginine can release nitric oxide under the action of a diabetic wound surface or an inflammation microenvironment to achieve the effects of resisting bacteria and promoting wound surface recovery, and the exosome successfully avoids the risks of cell survival defects, vascular embolism, immunological rejection and the like while retaining powerful bioactive components. The product has excellent antibacterial activity, degradability, tissue adhesion, injectable performance and self-repairing performance, and can be suitable for wounds in different shapes.

The application discloses a four-stage paddle thrombus-removing micro robot, a preparation method and a magnetic field driving thrombus-removing micro robot system, relates to the technical field of micro robots, and comprises a conical drill bit, a main straight rod and a four-stage paddle group, wherein the conical drill bit is made of a biodegradable material; the bottom of the conical drill bit is connected with the main straight rod; the main straight rod is internally provided with a thrombolytic drug; the four-stage paddle group is arranged on the outer circumferential surface of the main straight rod in an axial direction; the paddle group comprises three paddle blades which are centrally symmetrical to the axis of the main straight rod; the paddle blades in the adjacent two-stage paddle groups are arranged in a staggered manner; the paddle blades are of a round head structure; the thickness of the paddle blades gradually increases from outside to inside; and the surface of the micro robot is coated with a magnetic film and is subjected to directional magnetization treatment. The application can obtain strong movement ability and stable movement state under the accurate control of a movement system, realizes intravascular drilling and crushing of a thrombus, and can biodegrade and release the thrombolytic drug after surgery, so as to solve the problem of downstream vascular embolism after drilling.

The invention discloses a preparation method of yttrium-90 (90Y)-loaded magnesium lithium silicate and a hydrogel radiotherapy embolism agent, relates to the technical field of medical materials, and comprises the preparation method of yttrium-90-loaded magnesium lithium silicate and the hydrogel radiotherapy embolism agent. Lithium magnesium silicate is modified and treated by phosphate, and citric acid is complexed with < 90 > Y < 3 + >, so that interlayer cations of the lithium magnesium silicate are replaced, and < 90 > Y < 3 + > is stably loaded on the lithium magnesium silicate to prepare the < 90 > Y-lithium magnesium silicate compound. Yttrium-90 is a therapeutic nuclide, and a 90Y-magnesium lithium silicate loaded compound can be added into an embolism agent as a thixotropic agent to prepare a hydrogel radiotherapy embolism agent, so that dual effects of internal radiation and vascular embolism are realized.

The invention discloses a locally degradable vascular embolism spring ring. The spring ring comprises an inner core shaft; the degradable spring is sleeved on the inner core shaft; the macromolecular binding wire harness is used for binding and fixing the inner core shaft and the degradable spring; wherein a plurality of binding position points are arranged on the spring rings, the macromolecule binding wire harnesses are arranged at the binding position points, the macromolecule binding wire harnesses are wound on the spring rings by at least one circle to form binding winding lantern rings, and the wire harnesses of the binding winding lantern rings are locally embedded into gaps between the degradable spring rings. And the wire harness embedded in the gap between the degradable spring rings is also partially wound on the inner core shaft. The invention further discloses a manufacturing method of the locally degradable vascular embolism spring ring. Compared with the prior art, the problem that the inner core shaft and the outer-layer degradable spring displace and slide beyond the allowable range in the pushing process when the spring ring is placed into a blood vessel is solved.

The present application relates to a kind of hemangioma occlusion device, hemangioma occlusion treatment device and hemangioma occlusion system, hemangioma occlusion device includes mesh expansion structure and guide structure, the mesh expansion structure has from the unwinding state of spiral shape around from distal end to proximal end and the compressed state for being delivered from inside blood vessel to hemangioma;At least a part of the guide structure is arranged in the lumen of mesh expansion structure, and when the mesh expansion structure is in spiral shape, at least a part of the guide structure is unwound in the lumen of mesh expansion structure in spiral shape.The present application has the advantages of preventing hemangioma rupture, preventing vascular embolism, improving the coverage of tumor neck, promoting the formation of intratumoral thrombus, accelerating hemangioma embolism and the like while realizing stable and compliant tamponade.

The utility model relates to the technical field of medical instruments, and provides a plugging support and a plugging balloon catheter, and the plugging support comprises a supporting part and an intercepting part; the supporting part can be contracted and unfolded for supporting, one end of the intercepting part is connected with the supporting part, the other end of the intercepting part is gradually contracted and extends to form a cone shape, the supporting part and the intercepting part are both provided with hollowed-out parts, and a woven mesh is arranged in the hollowed-out part of at least one of the supporting part and the intercepting part. According to the utility model, the woven mesh is arranged in the hollow part of at least one of the supporting part and the intercepting part, so that the gap of the occlusion stent is further reduced, and the woven mesh can better leave substances in blood vessels, so that the occlusion time is shortened, and the clinical requirements of acute vascular embolism occlusion are met.

The utility model relates to the technical field of medical instruments, in particular to a vascular embolism stripping and suction catheter system. The vascular embolism stripping and suction catheter system comprises a catheter, a compressible and self-expanding thrombus cutting stripper and a traction silk thread, a traction cavity and a negative pressure cavity are formed in the catheter in the length direction of the catheter, the traction silk thread penetrates through the traction cavity, one end of the traction silk thread is connected with the thrombus cutting stripper, and the other end of the traction silk thread is connected with the negative pressure cavity. One end of the negative pressure cavity is communicated with the catheter, the other end of the negative pressure cavity penetrates out of the other end of the catheter, the thrombus cutting detacher can be compressed to be arranged in the traction cavity or can be released outside the catheter in a self-expanding mode, and the other end of the catheter is provided with a negative pressure connector communicated with the negative pressure cavity. The device has the advantages that the structural design is simple and reasonable, the wall-attached embolism can be effectively cut and crushed and then sucked out through negative pressure, and the embolism can be taken out more easily.

Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.”

The utility model discloses a tissue separation pad beneficial to microvascular anastomosis, which comprises a pad, an air cushion is arranged on the inner wall of the pad, a support is arranged in the air cushion, two suture pads are arranged above the pad, and the two suture pads can be attached to each other. The utility model relates to the technical field of vascular anastomosis, in particular to a tissue separation pad beneficial to microvascular anastomosis, which can play a role in physically separating tissues around a blood vessel from a lumen of the blood vessel through the matching of a gasket, an air cushion, a winding rope, a titanium alloy layer and a bracket, and provides a relatively pure anastomosis environment. In the process, some easily-coagulated substances, fat particles, vascular adventitia and other tissues are effectively prevented from entering a vascular lumen in the anastomosis process, vascular embolism is prevented, and the tissue separation pad beneficial to microvascular anastomosis can be expanded outwards all the time by means of the elasticity of the support, so that the tissue separation pad is more stable. And the phenomenon of vascular occlusion caused by extrusion of the tissue separation pad beneficial to microvascular anastomosis is avoided.

The invention provides a vascular embolism recurrence risk prediction method and device and electronic equipment. The vascular embolism recurrence risk prediction method comprises the steps that multi-modal data of a patient at each time point is acquired, the multi-modal data of each time point comprises at least two modal data of a vascular image, a medical text, biochemical test information and a physiological signal, and the multi-modal data of at least one time point comprises the vascular image; determining a first feature and a second feature according to the multi-modal data of each time point, the first feature being obtained by analyzing correlation between the modal data and reflecting a recurrence risk level of the patient at the current time point, and the second feature being obtained by analyzing a change rule of the multi-modal data along with time and reflecting a recurrence risk evolution trend of the patient; the vascular embolism recurrence risk of the patient in the future period is predicted according to the first feature and the second feature, and the prediction accuracy of the vascular embolism recurrence risk can be improved.

The invention provides a hydrogel material with an effect of supporting tissue cell growth as well as a preparation method and application thereof, and belongs to the technical field of medicines. The hydrogel material is prepared from the following raw materials: povidone, polyvinyl alcohol, agar, boric acid, edible tannin and polyacrylic resin II. The preparation method comprises the following steps: mixing the raw materials with water to obtain a mixed solution, and then carrying out a cross-linking reaction on the mixed solution through electron beam irradiation to obtain the hydrogel material with the function of supporting tissue cell growth. The hydrogel material is applied to preparation of vascular embolism agents. The hydrogel can enable a body to generate histological reaction on the hydrogel serving as a foreign body, fibroblasts wrap the hydrogel and then grow into the hydrogel, cells migrate and proliferate to form collagenous fiber tissue of a three-dimensional network structure, and then capillary and tissue cells grow into the hydrogel to form connective tissue; meanwhile, under the action that cells swallow foreign matters, the hydrogel is digested and degraded, and finally the diseased tissues are repaired.

The invention discloses body temperature responsive self-adhesive gel microspheres as well as a preparation method and application thereof, and relates to the technical field of medicines. The body temperature responsive self-adhesive gel microspheres comprise a photocuring structure stabilizing unit material and a body temperature responsive self-adhesive unit material; the photocuring structure stable unit material comprises at least one of a natural polymer derivative material and a synthetic polymer material; the body temperature responsive self-adhesive unit material can be subjected to chain segment migration and re-entanglement at a physiological temperature. The gel microsphere has good temperature-controlled self-adhesion capability and interface adhesion property, and can be used as an embolism agent for treating vascular embolism.

The invention belongs to the technical field of medical instruments, and provides a continuous flushing type balloon catheter device, an inner cavity is used for continuous perfusion of heparin water, an outer cavity is used for balloon dilatation to inject liquid or air, the device is stably fixed in a blood vessel through balloon dilatation, continuous perfusion of liquid in the blood vessel is achieved, and the continuous flushing type balloon catheter device is convenient to use. Therefore, the donor keeps the blood vessel (radial artery or superficial temporal artery) to keep certain tension to avoid distortion caused by collapse, continuous perfusion keeps the blood vessel cavity of the donor blood vessel clean and moist, the condition of vascular embolism blockage caused by foreign matters or thrombus in the donor blood vessel is avoided, thrombus formation is fundamentally prevented, and the donor blood vessel is protected from being damaged. Meanwhile, the continuous perfusion can enable the intracranial vascular anastomotic stoma to be in an open state, so that the smooth rate of vascular anastomosis can be kept, the operation area can be kept clean, and the situation that surrounding blood pollutes the anastomotic stoma and affects the smooth rate of the operation is avoided.

The invention relates to the field of biomedical materials, in particular to cyanoacrylate medical blood vessel blocking glue and a preparation method thereof.The cyanoacrylate medical blood vessel blocking glue is prepared from, by mass, 30-35 parts of 2-octyl cyanoacrylate, 7-8 parts of lactide modified hydroxyethyl methylacrylate, 0.02-0.03 part of polymerization inhibitor propyl gallate, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator and the balance water. By innovatively adopting various functional components and carrying out synergistic compatibility and precise preparation, compared with the prior art, the comprehensive performance of the product is remarkably improved, and the plugging agent has the advantages of rapid and reliable plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect and the like. Meanwhile, good biocompatibility, intraoperative developing capacity and a potential drug sustained release function are achieved, operation is easy and convenient, performance is stable, a safer and more efficient choice is provided for clinical vascular interventional therapy, and wide application prospects are achieved in the fields of cardiovascular and neurological intervention, peripheral vascular embolism and the like.

The present invention relates to a fresh wolfberry composition having the function of improving vascular embolism and a preparation method thereof, and relates to the technical field of vascular embolism treatment. The fresh wolfberry composition comprises the following components, measured by weight: 600-800 parts of fresh wolfberry fruit, 100-200 parts of fresh roxburgh fruit, and 40-80 parts of northern lily of the valley. The present invention is the first to use fresh wolfberry fruit as the main raw material, combined with appropriate amounts of fresh roxburgh fruit and northern lily of the valley as raw materials. The three ingredients work synergistically to produce a fresh wolfberry composition having the function of improving vascular embolism, providing a new approach for preventing and treating vascular embolic diseases.

The invention discloses a cerebrovascular embolism interventional thrombectomy device, and relates to the technical field of medical instruments. The vascular embolism interventional thrombectomy device comprises a container catheter, a pushing assembly is movably connected to the interior of the container catheter, and a containing assembly is fixedly connected to the inner wall of the container catheter; the pushing assembly comprises a position control pipe, the position control pipe is arranged in the container guide pipe, and the twitching pipe is arranged in the position control pipe; the pushing air bag is movably connected to the right side of the container guide pipe. According to the vascular embolism interventional thrombus extraction device, the pushing air bag is driven to one side of a thrombus, certain gas is injected into the pushing air bag, so that the pushing air bag is expanded, and the pushing air bag is extruded to be expanded by pulling the twitching tube; the whole thrombus can be taken out from the container catheter under the condition that too large supporting force is prevented from being generated on the inner wall of the blood vessel, and then secondary far-end embolism caused by thrombus tearing is avoided.

The utility model belongs to the field of injection needles, particularly relates to a pumpable double-cavity injection needle device, and aims to solve the problems that an existing hyaluronic acid injection needle is provided with a single cavity, whether the needle is placed in a blood vessel or not cannot be clearly confirmed before injection, so that an injection object is possibly injected into the blood vessel by mistake, and adverse complications such as tissue necrosis are caused by vascular embolism. According to the scheme, the device comprises a blood return needle cylinder, a medicine injection needle cylinder is fixedly arranged in the blood return needle cylinder, the front end of the blood return needle cylinder is in threaded connection with a connector, the connector is communicated with the blood return needle cylinder, one side of the connector is fixedly communicated with a blood return needle tube, and a medicine injection channel is fixedly arranged in the blood return needle tube. Through the arrangement of the double-cavity needle cylinder and the double-cavity needle tube, whether the needle head is in a blood vessel or not can be determined before injection, so that bad complications such as tissue necrosis and the like caused by the fact that liquid medicine is injected into the blood vessel due to the improper position of the needle head are avoided.

The present application provides a silk fibroin vascular embolism agent loaded with polyhydroxy phenolic compounds, which is prepared from a silk fibroin compound loaded with polyhydroxy phenolic compounds, wherein the silk fibroin compound loaded with polyhydroxy phenolic compounds is prepared by self-assembly of polyhydroxy phenolic compounds and silk fibroin, the silk fibroin is treated by a beta-fold conformation transformation process, and the mass ratio of polyhydroxy phenolic compounds to silk fibroin is <1:1; the vascular embolism agent is prepared by one of emulsification dispersion method, phase separation coagulation method, supercritical fluid technology, electrostatic adsorption method and dry granulation method. The vascular embolism agent has good biocompatibility and degradability, can effectively block blood flow, realize rapid hemostasis, and can be used for tumor vascular embolism treatment. Through the innovative self-assembly strategy, the mechanical properties of the silk fibroin microspheres are significantly improved. Compared with traditional hemostatic materials, the vascular embolism agent exhibits faster settling speed and higher hemostatic efficiency.

The invention discloses a droplet microsphere capsule as well as a preparation method and application thereof, and relates to the technical field of biomedical materials. The droplet microsphere capsule has a core-shell structure; the surface layer of the core is an oil phase; the shell includes extracellular vesicles. Extracellular vesicles are adsorbed and assembled on the surface of the core, so that the uniformity and the stability of the droplet microsphere capsule are remarkably improved. The droplet microsphere capsule has good deformability, can carry medicine, a developing agent and other functional components, and can be effectively used for vascular embolism and treatment of cancer, trauma, gastrointestinal hemorrhage and other diseases.

The application relates to the technical field of biological medicine, in particular to a radioactive embolism gel, a preparation method thereof and a radioactive embolism agent. The radioactive embolism gel comprises the following components: a radionuclide; a skeleton material comprising polyethylene glycol dimercapto; a chelating ligand comprising 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetracarboxylic acid-N-hydroxysuccinimidyl ester; wherein the chelating ligand is covalently grafted on the skeleton material, and the radionuclide is combined with the chelating ligand through chelation. The radioactive embolism gel has the characteristics of high radiochemical purity and good stability, can be made into a gel embolism agent integrating arterial tumor embolism and local radiotherapy, realizes the synergistic treatment of vascular embolism and internal irradiation, and has a good clinical application prospect.

The present invention discloses a method for preparing a drug delivery device and a drug delivery device. The monodisperse drug particles in the drug delivery device prepared by the present invention have a stronger binding force with the balloon surface, increasing the contact surface area with the balloon surface while significantly reducing the contact area with blood vessels during delivery, thereby reducing frictional resistance and drug shedding. Furthermore, because the drug particles are monodisperse, drug particles that fall off during expansion also fall off individually, preventing the formation of multiple drug particle aggregates, thereby avoiding vascular embolism caused by oversized particles. Furthermore, by providing a lubricant layer, the present invention significantly reduces frictional resistance during delivery, making delivery to distal tortuous and narrow blood vessels easier, while also reducing vascular damage caused by excessive pushing force.

The utility model relates to a thrombus filtration system, the thrombus filtration system comprises a delivery device and a filtration device, the delivery device comprises a connecting piece, a handle assembly and a sheathing canal, the handle assembly comprises a sliding assembly, the near end of the sheathing canal is connected with the sliding assembly, and the filtration device is connected with the connecting piece. The near end of the connecting piece penetrates through the near end of the sheathing canal and then is fixed in the handle assembly, the far end of the connecting piece is connected with the filtering device, the filtering device can be contained in the far end of the sheathing canal, and the sliding assembly can drive the sheathing canal to move relative to the connecting piece and the filtering device. The thrombus filtering system can intercept and capture fallen thrombus or calcification fragments in the operation process so as to prevent the thrombus or calcification fragments from rushing to the telecentric end along with blood flow to cause vascular embolism, and therefore the risks of local pain, tissue necrosis, hemiplegia, dementia and even death of a patient are avoided.

The invention belongs to the field of developers, and particularly relates to developable particles as well as a preparation method and application thereof. The developable particle provided by the invention is prepared by taking iodine-containing alcohol as a main body through a physical crushing or reversed-phase emulsification cross-linking process, and can be used for directly loading a medicine and developing for a long time. Compared with embolism drug-loading microspheres sold in the market, the drug adsorption capacity of the developable particles is larger than or equal to 140 mg / g within 3 min, the adsorption rate within 1 d is larger than or equal to 90%, the developable particles have the functions of developing, rapid drug loading and controllable release, and the developable particles can be used for preparing tissue gasket drugs, tissue filling drugs, tumor vascular embolism drugs and radiotherapy labeling drugs.

The invention belongs to the technical field of biomedical materials, and discloses a pre-potting injection gel preparation and application thereof. The pre-potting injection gel preparation provided by the invention is a gel particle preparation which is prepared by mixing micron-sized gel particles formed by crushing prefabricated gel with a carrier solution, defoaming, and then filling into a pre-potting injection instrument for preservation. The prefabricated gel block is prepared by mixing an aldehyde-terminated multi-arm polyethylene glycol solution and a multi-amino compound solution in equal volume. The pre-potting injection gel preparation provided by the invention can meet clinical application requirements in the aspects of soft tissue filling, radiotherapy isolation protection, vascular embolism and the like.