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Pharmaceutical composition for preventing senile osteoporosis

A technology of osteoporosis and composition, applied in the direction of drug combination, medical raw materials derived from ferns/filamentous plants, bone diseases, etc., can solve the problems of reducing the incidence of endometrial cancer in women

Inactive Publication Date: 2017-03-29
JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term oral estrogen and progesterone at the same time can reduce the incidence of endometrial cancer in women, but patients with venous thrombosis are contraindicated

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: Pharmaceutical composition for preventing and treating senile osteoporosis and preparation method thereof

[0035] The composition and parts by weight of the crude drug of the pharmaceutical composition for preventing and treating senile osteoporosis are: Daphne sativa 5250g, comb leaf 425g, euphratica picrolactone 245g, betulinic acid 55g, iris root 800g;

[0036] Preparation:

[0037] (1) According to the ratio of raw materials, take daphne daphne, comb leaves, eupholactone, betulinic acid, and iris root, mix well, use ethanol with a concentration of 16.5% by weight as a solvent, soak and extract at 35°C, and extract The number of times is 18 times, each extraction time is 38 hours, and the amount of solvent used each time is 64 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.03, Filtration, the medicinal liquid passes through the LKS02...

Embodiment 2

[0040] Embodiment 2: the pharmaceutical composition of preventing and treating senile osteoporosis and preparation method thereof

[0041] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating senile osteoporosis are: Daphne japonica 5200g, comb leaf 430g, eupholactone 230g, betulinic acid 60g, iris root 700g;

[0042] Preparation:

[0043] (1) According to the ratio of raw materials, take daphne daphne, comb leaves, eupholactone, betulinic acid, and iris root, mix well, use ethanol with a concentration of 16.5% by weight as a solvent, soak and extract at 35°C, and extract The number of times is 18 times, each extraction time is 38 hours, and the amount of solvent used each time is 64 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.03, Filtration, the medicinal liquid passes through the LKS0...

Embodiment 3

[0046] Embodiment 3: the pharmaceutical composition of preventing and treating senile osteoporosis and preparation method thereof

[0047] The composition and parts by weight of the raw material drug of the pharmaceutical composition for preventing and treating senile osteoporosis are: Daphne sativa 5300g, comb leaf 420g, eupholactone 260g, betulinic acid 50g, iris root 900g;

[0048] Preparation:

[0049] (1) According to the ratio of raw materials, take daphne daphne, comb leaves, eupholactone, betulinic acid, and iris root, mix well, use ethanol with a concentration of 16.5% by weight as a solvent, soak and extract at 35°C, and extract The number of times is 18 times, each extraction time is 38 hours, and the amount of solvent used each time is 64 times of the total weight of the crude drug, filtered to obtain medicinal residue A and extract A, extract A reclaims ethanol, concentrates to a relative density of 1.03, Filtration, the medicinal liquid passes through the LKS02 ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for preventing senile osteoporosis and a preparation method thereof. The pharmaceutical composition is composed of daphne tangutica, diplazium donianum, euparotin, betulinic acid, and root of iris speculatrix according to a certain ratio. The pharmaceutical composition can be made into various dosage forms by a conventional preparation technology and has a prominent effect on preventing senile osteoporosis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for preventing and treating senile osteoporosis and a preparation method thereof. Background technique [0002] The disease location of senile osteoporosis is mainly in the bones, involving kidney, liver and spleen and other viscera. "Suwen. Xuanming Wuqi Chapter" proposes that "the liver governs the tendons" and "the kidney governs the bones". "Lingshu. Benshen" also pointed out that sufficient liver blood can fully nourish the tendons of the limbs, thereby maintaining the normal activities of the human body; the growth, development and repair of bones all rely on the nourishment of kidney essence. Western medicine treats senile osteoporosis, generally using drugs that inhibit bone resorption, drugs that promote bone synthesis, and bone mineralization drugs. Its function is to strengthen the bone hardness in the hu...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P19/10A61K31/56A61K31/365
CPCA61K36/83A61K31/365A61K31/56A61K36/12A61K36/88A61K2236/333A61K2236/39A61K2236/55
Inventor 不公告发明人
Owner JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
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