Tissue regeneration-promoting corium elephatis ointment is characterized in that the traditional Chinese medicine ointment is prepared from the following raw materials by weight: 12-18 parts of crinis ustus, 12-18 parts of whole angelica, 24-36 parts of raw tortoise plastron, 24-36 parts of large rehmanniae radix, 37-50 parts of gypsum, 56-75 parts of raw calamine, 21-27 parts of prepared corium elephatis, 1.5-5 parts of sangusis draconis, 7.5-10 parts of frankincense, 7.5-10 parts of myrrh, 7.5-10 parts of acacia catechu, 600-800 parts of sesame oil, 56-75 parts of beeswax, and 56-75 parts of white wax. The ointment of the invention belongs to a pure traditional Chinese medicine preparation, is safe and reliable, has no toxic or side effects, has the effects of blood activation, pain relieving, tissue regeneration promotion, inflammation resistance, infection resistance, detoxification, astringency, incrustation promotion, and wound exudation reduction, can promote shedding of necrotic tissue, promote epithelium growth, reduce scar tissue hyperplasia, is safe, has good treatment effect on burning wound and scald, pressure sores, postoperative infection, ulcer, fester, non-healing wound, diabetic feet, and the like, is low in treatment cost, and high in curative effect, causes no recurrence, has an effective rate of 99% and a cure rate of 99%, and is an ideal external-use traditional Chinese medicine for treating ulcer with low cost.