675results about How to "To achieve the purpose of treatment" patented technology

The invention relates to a process for preparing an internal frame of a blood vessel with electrostatic fiber tectorial. The concrete procedure is that 1, preparing polymer solution or polymer solution with drugs or bioactive elements, 2 preparing to obtain nanometer/ micrometer fiber, 3, forming a fiber film structure on the surface of the internal frame of the blood vessel. The shape of a fabric prepared by the invention imitates the shape of an epimatrix of a natural cell, thereby being beneficial for cells to sticki and breed, moreover, the drugs and active elements such as growth factor can be loaded in the nanometer fiber by an electro-spin to be released slowly, and the internal frame of the blood vessel with electrostatic fiber tectorial has good mechanical function, thereby satisfying the need of clinical releasing. In an implanting area, the invention can effectively support a lesion blood vessel to ensure the smoothness of the lesion blood vessel or can avoid dangers such as blood leakage due to angiomatosis in a diseased region. Simultaneously, the invention is capable of slowing releasing the drugs if necessary.

The invention provides a rare earth upconversion nano crystal/silver difunctional composite nano material and a preparation method thereof as well as application thereof in preparation of medicine for treating tumour. The composite nano material can inhibit the growth of tumour tissue and can be used with anti-tumour medicine, thus improving medicine effect and achieving the aim of treatment; thecomposite nano material is difficult to decompose and has good light stability; damage to human body is less, the composite nano material can be taken as heat sensitizing agent and can absorb infrared light, the near infrared region (800-1200nm) is a transmission window of organism tissue, and damage of near infrared laser to human body is far less than that of laser in other wavebands, thus reducing damage to human body, being capable of being used as photothermal conversion agent and being superior when used for diagnosis and treatment on malignant tumour.

The invention relates to a preparation method of a shell core fiber covered endovascular stent graft. The steps are as follows: firstly, a polymer is dissolved in adaptive dissolvent to obtain solution with a certain concentration; secondly, medicine or an artificial polymer and medicine, and a bio-active element are dissolved in the adaptive dissolvent to obtain solution or suspension liquid; thirdly, the solution of the polymer and the medicine or the solution or suspension liquid of the medicine or bio-active element are respectively filled in two injectors, the speed of a micro injection pump, the voltage of an electrostatic generator and the distance of a receiving device are adjusted, fiber is obtained through the static spinning preparation, and the fiber is received as a tube shape or film shape structure; fourthly, the endovascular stent graft is fixed on a revolution axle, through the revolution of the endovascular stent graft, the static spinning fiber are directly received as fibrous membrane covered on the endovascular stent graft. The invention can effectively prevent smooth muscle cells from hyperplasia in the stent graft or from narrowing in the stent graft caused by the other functions, and the shell core fiber for the medicine loading can slowly release the medicine to attain the purpose of curing.

The invention relates to a micro-needle transdermal delivery patch with high penetration efficiency, and belongs to a medicament and equipment integrated patch product. The micro-needle transdermal delivery patch can painlessly and efficiently deliver medicament waiting delivery matters to the subcutaneous part, and achieves treatment, beautifying and health-care effects. In addition, under the stimulation of external force, heat, light, electricity, magnetic field, electric field and the like, the penetration effect can be accelerated, so that the micro-needle delivery patch has a curative effect which is not achieved in a common medicinal patch, the application range of the medicinal patch is expanded, and the curative effect of medicaments are improved. The invention relates to the structural design of the novel micro-needle transdermal delivery patch and the core technology of the implementation process, and the patch can be used for treating skin and shallow skin diseases and can also be used for treatment and related nursing operation of deep tissues and endocrine system diseases. The micro-needle delivery patch product conforms to the tide of future medical treatment, really realizes the advanced treatment concepts of painless delivery and happy treatment, is a novel patch product, and particularly has a broad market prospect for special crowds such as old people and children.

The invention relates to a vessel plug material used in intervene treatment. Wherein, said material is temperature-sensitive nanometer gel system based on polymer N-isopropyl acrylamide (PNIPAAm), which comprises polymer N-isopropyl acrylamide nanometer gel and dispersed medium, while the gel mass percentages is 3-20% and the particle diameter of temperature-sensitive nanometer gel is 50-1000nm. The inventive temperature-sensitive nanometer gel system also can contain developer, soluble antineoplastic. The invention can control the polymer monomer kinds and ratios, the crosslinker amount and the density of temperature-sensitive nanometer gel, to control the sol-gel transformation temperature of said system, and the inventive product has better external flow property and high sol-gel transformation speed, to be used to treat vessel plug, etc.

The invention relates to a paclitaxel-loaded sustained release nano-fibre material which comprises the components of bio-degradable polymer material and pure paclitaxel, the mol ratio of which is 1.33 to 10. The diameter of the nano-fibre is 90nm to 1.44micrometer, and the drug-loading rate can be regulated within the range of 0 percent to 100 percent. The preparation of the nano-fibre comprises the steps as follows: (1) the bio-degradable polymer material is solved in organic solvent and stirred to be solved completely to obtain lamella spinning solution A; (2) the white pure paclitaxel powder is solved in trifluoroethanol and stirred to be solved completely to obtain core spinning solution B; (3) clear transparent solutions A and B are respectively added into two injectors; the speed of a microinjection pump, the voltage of a static generator and the receiving distance between a grounded aluminum foil and a spinning needle are adjusted, and unordered drug-loaded nano-fibre is obtained by a coaxial electrostatic spinning technology. A nanometer control release system composed by the drug-loaded nano-fibre effectively controls the sustained release of the drug and is applied to the preparation of the drug for remedying malignant tumor.

The invention discloses low-temperature therapeutic equipment using a coolant. The therapeutic equipment comprises a refrigerating device, a one-way valve, a coolant storage tank, a coolant recovery tank, an air compressor, an air storage tank, an adjusting valve, a control system, a low-temperature probe and the like, wherein the air compressor compresses air into certain high pressure and stores the compressed air in the air storage tank; when the coolant, namely low-temperature silicone oil, refrigerated by the refrigerating device flows into the storage tank through the one-way valve and is accumulated to a certain amount, a liquid level sensor transmits a signal to a programmable controller to open the adjusting valve so as to charge the compressed air into the storage tank; the programmable controller controls the opening of the adjusting valve through a pressure signal detected by a pressure sensor, so that the low-temperature silicone oil is squeezed out of the storage tank by a corrugated pipe at a certain flow rate to flow to the low-temperature probe, and the silicon oil flowing out from the low-temperature probe returns to the recovery tank. The equipment can be applied to cold therapy on diseased tissues.

A Chinese medicine for preventing and treating the bacterial and viral diseases of aquatic animals is prepared from 12 Chinese-medicinal materials including astragalus root, Chuan-xiong rhizome, tangerine peel, rhubarb, etc.

The invention relates to a composite developing thermosensitive gel embolizing agent as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, preparing a mixed aqueous solution of an anticancer active substance, a thermosensitive material and a developing agent into composite developing thermosensitive gel; secondly, forming a composite developing thermosensitive gel embolizing agent by the composite developing thermosensitive gel and a coagulant on the scene, wherein the thermosensitive material is hydroxyl C1-4 alkyl cellulose, Pluronic, alginate or a mixture of the substances; the anticancer active substance is arsenic trioxide, docetaxel, cisplatin, carboplatin, nedaplatin, oxaliplatin, lobaplatin, miriplatin, siRNA or a mixture of the substances; the developing agent is a water-soluble developing agent of iodixanol, ioversol or iohexol and the like. The preparation method disclosed by the invention is simple and convenient, is suitable for industrial large-scale production, is particularly suitable for preparing an embolizing agent which is biodegradable and good in biocompatibility and is used for hemorrhagic diseases, and is especially suitable for preparing the composite developing thermosensitive gel embolizing agent for treating liver cancer, kidney cancer, lung cancer, prostate cancer, uterine myoma or splenic tumor and the like.

Relating to the fields of biotechnologies and gene therapy, the invention provides application of a gene modified mesenchymal stem cell in pulmonary fibrosis treatment. The gene modified mesenchymal stem cells are obtained through: in-vitro isolated culture and amplification of a mesenchymal stem cell (MSC) deriving from bone marrow and an umbilical cord, and recombinant adenovirus Ad-HGF mediated in-vitro modification of the MSC by a hepatocyte growth factor (HGF). By transplanting the gene modified MSC to a C57 mouse to intervene in radiation induced lung injury and fibrosis, exudation of a plurality proteins including albumin, IgM and the like from an alveolar space can be reduced, local inflammatory responses of the lung can be alleviated, and expression of TNF-alpha, soluble ICAM-1 and multiple factors is inhibited, expression of the profibrotic factor TGF-beta, the collagen gene col1 alpha 1 and col 3 alpha 1 can be inhibited, and pulmonary tissue collagen fiber deposition is reduced. The expression results of endogenous HGF and its receptor cmet show that endogenous HGF expression can be induced and endogenous MSC can home to injured parts. Therefore, the employment of HGF modified MSC in treatment of lung injury and fibrosis brought by various pathogenic causes is of great significance.

The invention discloses a double-saccule blood vessel inner conduct pipe wherein the pipe is provided with an opening on one end, and a securing sleeve on the other end, the outer wall of the pipe is covered by a first saccule and a second saccule spaced by a finite distance on the opening end of the pipe, the saccule tube connector is inserted into the inner cavity of the pipe through the securing sleeve and is in communication with the inner cavities of the two saccules. The pipe is provided with a blood output hole, which is provided with a blood transfusion tube.

The invention relates to a focusing magnetic field control system for nanoparticles. The focusing magnetic field control system comprises a focusing module, a magnetic conduction loop A03 and a control module, wherein the focusing module is connected with the magnetic conduction loop A03 via two pairs of magnetism gathering magnetic poles, the control module is connected with two pairs of excitation coils of the focusing module, the gathering direction, the gathering speed and the gathering region of the magnetic nanoparticles are jointly controlled by the magnetism gathering magnetic poles, the excitation coils and the magnetic conduction loop, the control module comprises a control system and a multi-path current excitation system, and the control system is connected with the multi-pathcurrent excitation system.

The invention relates to a traditional Chinese medicine combination for treating infant diarrhea, pertaining to the traditional Chinese medicine field of external application. The medicine combination comprises such formula as 10 portions to 15 portions of Chinese goldthread, 10 portions to 15 portions of amoorcorn tree bark, 15 portions to 20 portions of semen amomi, 10 portions to 15 portions of burnt hawthorn fruit, 15 portions to 20 portions of nutgall, 10 portions to 15 portions of windflower, 10 portions to 15 portions of clove, 15 portions to 20 portions of rhizoma atractylodis, 10 portions to 15 portions of cinnamon, 10 portions to 15 portions of Euodia ruticarpa, 15 portions to 20 portions of white pepper, 10 portions to 15 portions of radix codonopsis pilosulae, 15 portions to 20 portions of radix angelicae formosanae, 10 portions to 15 portions of rhizoma atractylodis alba, 15 portions to 20 portions of radices saussureae, and 15 portions to 20 portions of massa medicata fermentata. The medicine has the functions of removing fever, dryness and wetness, strengthening spleen and arresting diarrhea, enhancing digestion and removing food retention, eliminating dampness and detoxification, tonification and supplying healthy energy, dispersing coldness and killing pain since that the compatibility of the raw materials of the medicine is scientific and rigorous, and the formula is scientific and complete. The external application of the medicine enables the safety and convenience of the medicine; the effective absorption through the navel can realize the good treatment with short treatment period.

The invention discloses a medicine for treating facioplegia, which is prepared by 18 Chinese herbal medicines such as Chang bamboo, monkshood, liquorice, angelic sinensis and the like and can be made into capsules, pills and plaster; and the medicine can quickly activate the nervous function of the face, has fast effect, high recovery rate, and non-recurrence without sequela, and is widely applied to the treatment of a plurality of diseases such facioplegia, prosopospasm, musculus facialis numbness, trigeminal neuralgia, etc.

The present invention is one kind of muscular atrophy treating medicine composition capable of dredging meridian, promoting blood circulation to disperse blood clots, eliminating external evil, invigorating spleen and kidney, raising body's immunity and reaching Yin-Yang balance. It is prepared with eight kinds of Chinese medicinal materials, including astragalus root, cassia, human placenta, schisandra, antler glue, etc. and through dispersing antler glue in boiling water, heating the medicine materials with water at 120 deg.c and 1.2-1.5 atm for 30-40 min to obtain medicine liquid, and packing. The present invention can regenerate necrotic muscle molecule to reach the aim of curing muscular atrophy.

The invention relates to a medicine for treating rheumatoid arthritis, which is prepared by the following steps: taking selected and cleaned antler, radix salviae miltiorrhizae, angelica, stir-fried radix paeoniae alba, radix rehmanniae preparata, hemlock parsley, peach kernel, safflower, prepared monkshood, cassia twig, stir-fried rhizoma atractylodis, stir-fried coix seed, eucommia carbon, pawpaw, radix achyranthis bidentatae, himalayan teasel root, mistletoe, black-tail snake, centipede, futokadsura stem, schizophragma integrifolium, homalomena rhizoma, club moss, american lopseed, radix gentianae macrophyllae, radix clematidis, asarum, radix sileris, scorpion and gastrodia tuber; and evenly mixing, pulverizing into 100-120 mesh medicinal powder, adding honey, drawing the pattern, and making pills. The medicine provided by the invention has the effects of warming and invigorating the kidney yang, managing blood, dispersing pathogenic wind and cold dampness and exciting the junior fire, and can perform the functions of alleviating pain, promoting the subsidence of swelling, softening the tendon and strengthening the bone, thereby achieving the goal of treating rheumatoid arthritis.

The invention relates to a medical preparation containing plant material resultant of reaction, in particular to a strengthening kidney and clearing wind tea preparation for treating gout. The invention contains more than ten pure traditional Chinese medicinal materials, namely, radix pseudostell, Milkvetch Root, Common Yam Rhizome, Radix Salviae Miltiorrhizae, Cortex Moutan, Harms Manyprickle Acanthopanax, Radix Achyranthis Bidentatae, rhizoma anemarrhenae, Radix Paeoniae Rubra, Radix Rehmanniae, balsamine, pawpaw, Coix Seed, Sharpleaf Galangal Fruit, Herba Aristolochiae Mollissimae, green tea, Largeleaf Gentian Root and Plantain Seed. The raw materials are prepared into tea preparation through the conventional modern Chinese traditional medicine production process. After the clinical use, the invention has the advantages of evident effect, convenient use and no any side effect and can effectively avoid the stimulation action to liver, kidney and stomach; thereby the tea preparation is worthy of promotion and application. The invention is easy for use, one bag of medicine tea is taken and infused with boiling water and two bags are taken for one day. The invention can be drunk frequently instead of tea in any time until the tea becomes pale.

A yeast in the form of micro capsule for controlling the release of protein medicine to treat uremia, hepatal failure, phenylketonuria, cancer, etc has the sodium alginate-chitosan-sodium alginate structure, and the yeast is dispersed proportionally in the liquid contained in the micro capsule.

An oral applied Chinese medicine for treating both infectious pyreticosis and non-infectious fever diseases, and some infectious diseases is prepared from 8-14 Chinese-medicinal materials including sweet wormwood, bamboo shavings, pinellia tuber, tangerine peel, etc through steaming, reflux extracting in alcoholic aqueous solution and vacuum distilling for concentrating. Its advantage is high curative effect (93.3%).

The invention relates to a Chinese medicine for treating breast obstruction and pain, which is characterized by comprising the main components: 9g of angelica, 30g of hoantchy root, 6g of salvia miltiorrhiza, 9g of prepared pangolin, 15g of fried seed of cowherb, 6g of tetrapanacis medulla, 30g of dried snake gourd fruit, 9g of radix rhapontici, 9g of geranium wilfordii, 5g of honey-fried licorice root, 3 inches of welsh-onion stalk, and the like. The preparation method comprises the following steps: placing the Chinese medicinal materials into a container; adding water, decocting for 30min; and getting 200ml of juice, wherein the juice can be taken after the breakfast and the supper through warming, one potion is taken every day, and two potions are taken as one treatment period. The invention is prepared by pure Chinese medicines through adopting the traditional preparation method, maintains the property of the medicine, has the efficacy of promoting blood circulation by removing blood stasis and promoting lactation and achieves the purpose of treatment without side effect.

The invention relates to the technical field of medical devices, in particular to an intracranial stent graft. The intracranial covered stent includes a stent body and a film coated on the stent body, the stent body is a self-expanding network tube structure formed by interconnecting a plurality of unit grids, and the film is covered on the The middle part of the stent body; the intracranial covered stent automatically expands to fit the vessel wall at body temperature, and can form a closed channel in the lesion vessel under the premise of keeping the parent artery unobstructed, so that the blood flow of the lesion is completely consistent with the normal blood circulation. Isolate and isolate the aneurysm, change the hemodynamics in the tumor, and promote the formation of thrombus. Compared with using coils or other embolic agents to treat aneurysms, the covered stent graft of the present application is more economical and simple, and can avoid the risk of aneurysm rupture and bleeding during the operation; compared with parent artery balloon occlusion or ligation, Stent-graft technology appears safer by preserving artery patency.

The present invention is plant extractive and natural compound for treating leukaemia and multiple myeloma. The natural compound includes amarylline, homoamarylline, narcissus krasin, ungernine, preungernine, amarylline and pseudoamarylline is used mainly in treating multiple myeloma. The said plant extractive, compound and their derivative are matched with other medicine to form compound medicine for treating leukaemia and multiple myeloma with less toxic side effect and higher curative effect. The plant extractive and the natural compound can inhibit cell protein synthesis, inhibit cell proliferation and promoting cell death to reach the aim of treating leukaemia and multiple myeloma.