11 results about "Cholecystitis" patented technology

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating hepatobiliary diseases, the traditional Chinese medicine composition has the effects of soothing liver-gallbladder, clearing away heat and toxic materials, promoting qi circulation, dispersing blood stasis, regulating qi, activating blood, benefiting gallbladder and removing urinary calculus, and is clinically used for treating cholelithiasis, cholecystitis, jaundice, hepatitis and other diseases. The preparation has the advantages of good curative effect, small side effect, low price, convenience in taking and the like, and exerts the unique advantage of the traditional Chinese medicine in treating hepatobiliary diseases.

The invention provides a Mongolian medicine tablet which is characterized by comprising extract powder prepared from herba violae, rhizoma picrorhizae, fructus gardeniae and dianthus superbus, silica gel, lactose, magnesium stearate, povidone and a coating layer. The invention also provides a preparation method of the Mongolian medicine tablet. The preparation method is characterized by comprising the following steps: (1) preparing extract powder; (2) preparing a tablet core; and (3) preparing a coating layer. The invention further provides application of the Mongolian medicine tablet in preparation of a medicine for treating cholecystitis.

A method for preparing a drug for treating bovine cholecystitis belongs to the field of biological veterinary medicine. The present invention utilizes the original ecological pathogens of bovine cholecystitis, and further adds bovine blood, trace elements, and freeze-dried Escherichia coli powder, freeze-dried enterococcus powder, freeze-dried Pseudomonas aeruginosa powder, and lecithin. Weak ultrasound is used in a buffer solution to activate the activity of various pathogens, and in the intelligent cultivation process, the corresponding antimicrobial peptides and antimicrobial proteins are strongly induced in the body of the big-headed golden fly larvae. The antimicrobial peptides and antimicrobial proteins have the characteristics of high biological activity and broad spectrum of action. Clinical treatment results show that the drug prepared by the present invention has good efficacy and high efficiency. The production process of the present invention is easy to industrialize and control, the product consistency is good, energy is saved, and it is suitable for large-scale production.

This invention relates to a choleretic traditional Chinese medicine composition, its preparation method, and its application, belonging to the field of traditional Chinese medicine preparation technology. The microcapsules prepared from this choleretic traditional Chinese medicine composition consist of a core and a coating. The core contains a traditional Chinese medicine extract, pregelatinized starch, sodium alginate, and croscarmellose sodium. The coating contains hydroxypropyl cellulose and hydroxypropyl methylcellulose E5, PEG4000, and talc. The traditional Chinese medicine extract is made from Artemisia capillaris, Lysimachia christinae, Rheum palmatum, Scutellaria baicalensis, Taraxacum mongolicum, Forsythia suspensa, Curcuma longa, Curcuma longa, Bupleurum chinense, Citrus aurantium, and Aucklandia lappa. This choleretic traditional Chinese medicine composition has the effects of promoting bile flow and expelling gallstones, detoxifying and reducing swelling, with a stable drug release rate, definite efficacy, and few toxic side effects. It can be used for the prevention and / or treatment of acute and chronic gallstones and / or cholecystitis.

This invention provides an extract of *Cimicifuga foetida*, made from *Cimicifuga foetida* produced in Guizhou Province, using an intermittent warm percolation method for water extraction. The extract contains 10%-25% cimicifugoside, 3%-15% iso-cimicifugoside, and 20%-50% plantago asiatica glycoside. The preparation method and applications are also disclosed. The *Cimicifuga foetida* extract provided by this invention has a high content of active ingredients and significant anti-inflammatory and litholytic pharmacological activities. It can be used as a raw material for the treatment and adjuvant treatment of cholecystitis, gallstones, hydronephrosis, kidney stones, nephritis, bladder stones, and uric acid stones. It can also be used as an intermediate raw material for the separation and purification of plantago asiatica glycoside, cimicifugoside, and iso-cimicifugoside chemical standards or reference standards. The preparation method provided by this invention effectively solves the problem of extraction and enrichment of active ingredients in *Cimicifuga foetida*, and has advantages such as low production cost, ease of large-scale production, and stable and controllable quality.

According to an aspect, a method of cholecystitis treatment includes: forming a communication hole that communicates a gallbladder and a duodenum; and arranging a bypass tube extending from a cystic duct to the duodenum through an inside of the gallbladder and the communication hole.

The invention provides a temperature-controlled thrombolysis device for minimally invasive puncture drainage of acute cholecystitis, and relates to the technical field of medical equipment.The temperature-controlled thrombolysis device comprises an infusion pump and an infusion pipeline leading-out connector, a push plate is pushed to drive two sets of rubber arc-shaped plates to get close to each other until the two sets of rubber arc-shaped plates are completely attached, an infusion tube is wrapped, then a locking screw is rotated, and the infusion tube is wound. The ends of the first heat-preservation arc-shaped strip and the second heat-preservation arc-shaped strip extend into the inner side of the fixing frame and are tightly attached to the outer surface of the push plate, the positions of the push plate and the rubber arc-shaped plate are locked through the jacking force of the locking screw, in the process, the first heat-preservation arc-shaped strip and the second heat-preservation arc-shaped strip are in synchronous butt joint, then the sealing wrapping belt surrounds the butt joint position in the circumferential direction to cover a connector gap, and fixing is completed by pressing the first hook-and-loop fastener and the second hook-and-loop fastener. Finally, the infusion tube is sealed in a space formed by the rubber arc-shaped plate and the heat preservation arc-shaped strip, by means of the low heat conduction characteristic of the heat preservation arc-shaped strip, the preset temperature of thrombolysis medicine in the tube can be stably maintained, interference of temperature fluctuation on the thrombolysis effect is effectively avoided, and the stability and effectiveness of the medicine effect in the treatment process are guaranteed.

A compound of formula (I) or a salt thereof are provided:wherein R1, X and R3 are defined in the specification, useful in the treatment of disorders mediated by KMO such as acute pancreatitis, chronic kidney disease, other conditions associated with systemic inflammatory response syndrome (SIRS), Huntington's disease, Alzheimer's disease, spinocerebellar ataxias, Parkinson's disease, AIDS-dementia complex, amylotrophic lateral sclerosis (ALS), depression, schizophrenia, sepsis, cardiovascular shock, severe trauma, acute lung injury, acute respiratory distress syndrome, acute cholecystitis, severe burns, pneumonia, extensive surgical procedures, ischemic bowel, severe acute hepatic disease, severe acute hepatic encephalopathy or acute renal failure.

A method comprises obstructing at least a portion of an inside of a gallbladder using a barrier, and suppressing, using the barrier, contacting at least a portion of an interior wall of the gallbladder with a bile from a cystic duct.

The invention provides a traditional Chinese medicine composition for treating cholecystitis. The traditional Chinese medicine composition is prepared from the following raw material medicines: desmodium styracifolium, lygodium japonicum, endothelium corneum gigeriae galli, radix curcumae, pinellia ternate, scutellaria baicalensis, coptis chinensis, radix paeoniae alba and fructus aurantii. Animal experiment research results show that the traditional Chinese medicine composition has an obvious treatment effect on guinea pig cholecystitis caused by lincomycin hydrochloride, can obviously reduce guinea pig bile volume and reduce guinea pig serum TNF-alpha and IL-1beta, and has a recovery effect on liver function damage.

Provided is a pharmaceutical composition for treating and / or preventing a disease attributable to an obese condition, particularly an obesity disease, which has an excellent MGAT2-inhibiting activity and is at least not accompanied by at least one side effect selected from digestive tract disorders, chleystitis, heart beat increase, hypoglycemia, acute pancreatitis, abnormal hemostasis, hepatic disorders, renal disorders and embryonic lethality.　Also provided is a pharmaceutical composition which is very useful for body weight management in obesity, i.e., body weight reduction and body weight maintenance after body weight reduction.　This pharmaceutical composition for treating and / or preventing a disease attributable to an obese condition contains a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.