64 results about "Streptococcus hemolyticus" patented technology

The present invention relates to nanosilver-containing antibacterial and antifungal granules ("NAGs"). The NAGs have longlasting inhibitory effect on a broad-spectrum of bacteria and fungi, which include, but are not limited to, Escherichia coli, Methicillin resistant Staphylococcus aureus, Chlamydia trachomatis, Providencia stuartii, Vibrio vulnificus, Pneumobacillus, Nitrate-negative bacillus, Staphylococcus aureus, Candida albicans, Bacillus cloacae, Bacillus allantoides, Morgan's bacillus (Salmonella morgani), Pseudomonas maltophila, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Bacillus subtilis, Bacillus foecalis alkaligenes, Streptococcus hemolyticus B, Citrobacter, and Salmonella paratyphi C. The NAGs contain ground stalk marrow of the plant Juncus effusus L. which has been dispersed with nanosilver particles. The nanosilver particles are about 1-100 nm in diameter. Each of the nanosilver particles contain a metallic silver core which is surrounded by silver oxide. The present invention also provides a process for making the NAGs. The NAGs can be used in a variety of healthcare and industrial products. Examples of the healthcare products include, but are not limited to, ointments or lotions to treat skin trauma, soaking solutions or cleansing solutions for dental or women hygiene, medications for treating gastrointestinal bacteria infections, sexual related diseases, and eye diseases. Examples of industrial products include, but are not limited to, food preservatives, water disinfectants, paper disinfectants, construction filling materials (to prevent mold formation).

The present invention provides a gene chip for quickly detecting pathogens from food source, discloses the preparation method of said gene chip and provides 26 oligonucleotide probe sequences for detection. Said gene chip can quickly, accurately and high-effectively detect and identify the class of the pathogens in food, and its detection range includes staphylococcus aureus, Shiga's bacillus, salmonella, colibacillus 0157, bacillus proteus, mononuclear hyperplastic listerella, enterocolitis yersinia, aeruginous pseudomonads, vibrio parahaemolyticus, vibrio cholerae, bacillus cereus, beta hemolytic streptococcus, coconut fermentation pseudomonads, boticin, vibrio jejuni and bacillus perfringens, etc.

The invention belongs to the medical technical field and discloses the application of high-purity in the preparation of antibacterial medicine, antiviral medicine and other medicines. The invention proves the antipyretic, anti-inflammation, immunity enhancement, antibacterial and anti-virus effects of high-purity forsythiaside through the following experiments: (1) the experiment that high-purity forsythiaside has antipyretic effect on fever rats; (2) the experiment that high-purity forsythiaside inhibits xylene-induced mice ear edema, xylene-reduced capillary permeability of mice; (3) the experiment that high-purity forsythiaside increases carbon clearance ability of mice and increases the lymphocyte transformation rate; (4) the experiment that high-purity forsythiaside has vitro anti-influenza A type virus effect and in-vivo anti-respiratory syncytial virus effect; (5) the experiment that high-purity forsythiaside has vitro inhibition effects on beta-hemolytic streptococcus, staphylococcus aureus, streptococcus viridans and staphylococcus epidermidis.

The invention provides a truncated-form streptococcus hemolyticus bacteriolysin O gene and an ASO detection kit. According to the invention, part of SLO gene fragments are cloned, and the part of SLO genes are cloned into an expression vector of escherichia coli and the like so as to realize mass expression and facilitate purification. In particular, the invention provides a DNA sequence which has a base sequence as shown in SEQ ID NO:1. According to the invention, the truncated-form SLO sequence can greatly improve the yield of SLO protein; more than 150 mg of SLO protein can be obtained through purification of one liter of bacterial culture, and the purity is more than 90%; immunological tests prove that the sectionally expressed SLO still maintains the specific immunogenicity.

The invention discloses an essential oil composition prepared by performing rectification and compounding processing on the raw materials comprising 4-terpilenol type tea-tree-oil and eucalyptus grandis x e.urophylla essential oil, and provides the formula, a preparation method and the composition content of the essential oil composition; and the composition has antibacterial insecticidal functions. A gas chromatography method is employed to determine the main content. The method is accurate, stable and easy to operate, is adaptable for industrial production demands, and can help to effectively control the quality of the essential oil composition. The essential oil composition has small toxicity, has different levels of inhibition effects on six pathogens comprising staphylococcus aureus, staphylococcus epidermidis, beta hemolytic streptococcus, escherichia coli, pseudomonas aeruginosa and candida albicans which can cause skin infection, and has antibacterial and insecticidal activities. The preparation method is reasonable and stable, short in production period, suitable for industrial production, and good in application prospect.

The invention relates to a honeysuckle antibacterial composition which includes a honeysuckle extract, in effective dose, and auxiliary materials. The invention also discloses a preparation method and an application of the composition. The composition can effectively kill pathogenic bacteria, and has excellent killing effects on pathogens, such as staphylococcus aureus, escherichia coli, streptococcus hemolyticus and the like, which cause skin inflammation, antibacterial rate being not less than 60%. The honeysuckle antibacterial composition has excellent biocompatibility, is low in cytotoxicity and is high in safety, has excellent anti-inflammation and sterilization effect, is wide in available range, and also can be applied to infants and women in lactation period.

The invention discloses incense for eliminating plague, which is prepared from Chinese atractylodes rhizome, dried duckweed, dahurian angelica root, argyi leaf, realgar, nard, kaempferia galamga, nutgrass galingale rhizome and sweet wormwood. The incense can dispense fragrance so as to sterilize air, purify filth, clear away heat and toxic material such as influenza virus, encephalitis B virus and the like, kill bacteria such as tubercule bacillus, Klebs-Loeffler bacillus, streptococcus hemolyticus, and the like. After the incense is fired, the generated smoke has no harm and toxic and side effects to persons and livestock, the smelt is pure and mild, no peculiar smell is emitted, and the incense can be used for prevention of infectious diseases, evil influence, epidemic virus, pestilence, arashiyama and influenza virus and sterilization in stations, schools, hospitals, hotels and large cultivation farms.

The invention discloses lactobacillus harbinensis and application thereof. The lactobacillus harbinensis (M1) has a preservation number of GDMCC No.60305, and is preserved in guangdong culture collection center. The invention provides the application of the lactobacillus harbinensis as probiotics. The lactobacillus harbinensis is sensitive to antibiotics of ampicillin, tetracycline, chloramphenicol and the like, the safety meets the requirements of EFSA, and supernate of the lactobacillus harbinensis has significant effects of inhibiting listeria monocytogenes, streptococcus hemolyticus, staphylococcus aureus and the like. The invention further discloses the application of the lactobacillus harbinensis in fermented soymilk; a strain is used for fermenting the soymilk individually, the acid-producing capability is high, a viable count is large, the contents of substances with beany flavors are reduced or even zero, the contents of fermented milk characteristic aroma components are obviously improved, and a sensory flavor of the fermented soymilk is greatly improved, so that the lactobacillus harbinensis is an optimized starter of matrices, which are rich in plant oligosaccharide, ofsoybeans and the like.

The invention discloses a phage-containing spray type environment disinfectant as well as a preparation method and an application thereof, which belongs to the technical field of biological disinfection, the effective components of the disinfectant comprise an escherichia coli bacteriophage CCTCC NO.M2016539, a staphylococcus aureus bacteriophage CCTCC NO.M2016535 and a hemolytic streptococcus bacteriophage CCTCC NO.M2019227, wherein the ratio of the effective components is 1: 1: 1; when the disinfectant with the titer larger than or equal to 1*10<10>pfu/ml is sprayed in the living environmentaccording to the dosage of 50-100 ml/m<3>, the disinfectant has a broad-spectrum bactericidal effect on common pathogenic bacteria and is high in specificity, a SM buffer solution and cane sugar canprotect the stability of the titer of bacteriophage, and long-term use and storage of the disinfectant are facilitated; the purifying effect on living environment is good, safe and non-toxic.

The invention provides the application of quercetin in the preparation of medicine for preventing or treating diseases caused by influenze virus, adenovirus, staphylococcus aureus and/or streptococcus hemolyticus and the like, and a pharmaceutical composition thereof. The pharmaceutical composition has the activity for resisting the influenze virus being equivalent to oseltamivir.

The invention relates to a preparation method of a toilet paper product containing graphene, and discloses a process of medicinal plant papermaking. The process comprises the steps of screw extrusionprocessing, cooking, washing, papermaking, paper product modification, etc. The preparation method is characterized in that medicinal plant is used as a raw material to prepare fibers, and ultrasonicand ethanol methods are used in combination. The prepared paper product containing graphene has good softness and high strength, and no harmful chemicals are introduced during the whole process, so that the hygienic characteristic of the fibers is ensured; the prepared paper product has health care functions and effectively inhibits bacteria and resists bacteria; and since a graphene dispersion isadded during a pulping process, the obtained product has good antibacterial properties, and in particular, plays effective inhibiting and killing effects on staphylococcus aureus, escherichia coli, and streptococcus hemolyticus.

The oral digestible film includes water soluble polymer, enzyme and/or polypeptide in effective antibacterial amount. Test shows the oral digestible film can kill Staphylococcus aureus, colibacillus, Candida albicans, Streptococcus hemolyticus, Klebsiella pneumoniae and other disease-causing bacteria. The rat vagina mucous membrane stimulating reaction test shows the highest total integration value being zero, and the oral digestible film has no any stimulation to oral cavity mucous membrane. Halimeter test proves its oral cavity protecting effect in four hours and capacity of protecting fresh oral smell. The oral digestible film is used in killing harmful bacteria in oral cavity, keeping clean oral cavity and preventing and treating oral diseases.

The invention relates to an excellent microorganism strain for space mutation, in particular to a good microorganism strain for space mutation, and the preparation method and the application thereof. The discoveries that the bump of a cancer patient infected by hemolytic streptococcus can subsidise naturally and the hemolytic streptococcus and the preparation thereof have a certain of biological activities are made is as early as in the 19th century. In the invention, the special environment of the outer space is utilized to deliver the strains to the outer space through carrying the 22nd recoverable experimental science satellite, the 22nd recoverable experimental science satellite safely returns after traveling for a certain period of time, the suppresormutation strains are eliminated, the forward mutation strains with excellent features are selected out for re-screening, and ultimately the excellent microorganism strains with vigorous life, quick growth speed, high fermentation yield, short fermentation period, high polypeptide content, stable hereditary property, strong productive adaptability and space cumulative effect. The microorganism strain can be applied to the strains for industrialization production, and has the advantages of high output, wide application range, low cost and high effective component content.

The invention provides a traditional Chinese medicine composition for treating tonsillitis. The traditional Chinese medicine composition comprises the following components, by weight: 5 to 30 parts ofhoneysuckle, 5 to 30 parts of houttuynia cordata, 5 to 20 parts of the root of common peony, 5 to 15 parts of argy wormwood leaf and 5 to 15 parts of mint. Experiments show that the traditional Chinese medicine composition provided by the invention is capable of obviously inhibiting beta hemolytic streptococcus and staphylococcus aureus and inhibiting mouse ear swelling caused by xylene. Iin addition, clinical experiment results also show that the traditional Chinese medicine composition or the preparation thereof has a remarkable effect in the aspect of treating tonsillitis.

The invention relates to paper prepared from wastes of agriculture and forestry and a preparation method for the paper. A disclosed process for preparing fibers from the wastes of agriculture and forestry comprises the procedures of steaming treatment, screw extrusion, mechanical pulping, graphene dispersion solution modifying and the like. According to the method, the wastes of agriculture and forestry serve as a raw material for preparing the fibers, and screw extrusion and mechanical pulping are combined, so that the fibers prepared by the method are high in yield and low in Kappa number; and no harmful chemical is introduced in the entire process, so that the hygienic characteristic of the fibers is ensured. Due to a graphene dispersion solution added during pulping, the obtained product has relatively good conductive function and antibacterial performance and particularly plays a role in effectively inhibiting and killing staphylococcus aureus, escherichia coli and streptococcus hemolyticus.

The invention relates to an excellent microorganism strain for space mutation, in particular to a good microorganism strain for space mutation, and the preparation method and the application thereof. The discoveries that the bump of the cancer patient infected by hemolytic streptococcus can subsidise naturally and the hemolytic streptococcus and the preparation thereof have a certain of biological activities are made is as early as in the 19th century. The invention utilizes the special environment of the outer space to deliver the strains to the outer space through carrying the 21st recoverable experimental science satellite, the 21st recoverable experimental science satellite safely returns after traveling for a certain period of time, the suppresormutation strains are eliminated, the forward mutation strains with excellent features are selected out for re-screening, and ultimately the excellent microorganism strains with vigorous life, quick growth speed, high fermentation yield, short fermentation period, high polypeptide content, stable hereditary property, strong productive adaptability and space cumulative effect. The microorganism strain can be applied to the strains for industrialization production, and has the advantages of high output, wide application range, low cost and high effective component content.

A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly Streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the invention can be formulated for use as immunogenic compositions. Also disclosed are methods for immunizing against and reducing infection caused by β-hemolytic streptococci.

The invention provides a composition for upper respiratory tract infection. The composition is characterized by comprising the following components in parts by weight: 1-5 parts of chlorogenic acid and 1-5 parts of artemisone. Experiments show that the composition provided by the invention can significantly inhibit LPS or PolyI: C induced generation of inflammatory factors of macrophages RAW 264.7, and has certain bacteriostatic activity on staphylococcus aureus, haemophilus influenzae, streptococcus pneumoniae and hemolytic streptococcus, and in-vitro and in-vivo experiments also show that the composition has the activity of inhibiting influenza viruses.

The invention provides an antibacterial cleaning composition and wound plaster for wounds, and relates to the field of medicines. Active components of the antibacterial cleaning composition comprise acomposite yolk antibody, wherein the composite yolk antibody is prepared by the following method of mixing staphylococcus aureus with escherichia coli, baumanii, pseudomonas, group A streptococcus and candida albicans, which are inactivated to obtain a bacterial strain mixture, and enabling the bacterial strain mixture to dissolve to prepare composite antigen; and injecting the composite antigeninto a chicken body, performing immunologic facilitation, collecting eggs laid by chickens subjected to supplementary immunization, performing separation from the eggs, and performing refining, so that 6 pathogenic bacteria can be effectively restrained. Besides, the preparation method is simple, and antibodies can effectively exist, are in mutual coordination, are good in activity and good in specific disinfectant effects, and do not influence microecology balance. The wound plaster containing the antibacterial cleaning composition can effectively sterilize and clean the wounds, can prevent the wounds from being infected, and can promote the healing of the wounds.