Medicament for purpruick

A drug and purpura technology, applied in drug delivery, drug combination, medical formula, etc., can solve the problems of high risk, side effects, and high cost of surgery, and achieve the effects of promoting immune function, hematopoietic function damage repair, and improving antibody activity

Active Publication Date: 2008-06-18
苏州弓正生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Other treatment methods such as platelet transfusion, splenectomy, etc. can achieve certain curative effect, but most patients cannot bear it due to fast consumption, high cost, large side effects and high risk of operation
So far, Western medicine still lacks effective drugs for its specific treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: 15 parts of astragalus, 15 parts of sweet potato vine, 6 parts of Eclipta, 10 parts of Selaginella, 2 parts of Panax notoginseng, 2.5 parts of peanut shell, 6 parts of licorice

[0032] The above 8 flavors, 4 flavors of Astragalus, Ligustrum lucidum, Eclipta, Panax notoginseng, add 70% ethanol to reflux extraction twice, add 6 times the amount for the first time, add 5 times the amount for the second time, each time for 2 hours, combine Extract, filter, recover ethanol from the filtrate and concentrate appropriately, and concentrate for later use; add 10 times the amount of water to decoct sweet potato vine, Selaginella, peanut coat, and licorice for 3 times, each time for 1 hour, combine the decoctions, and concentrate to 1 : 1, let cool, centrifuge, mix the supernatant with the above concentrated solution, concentrate to a thick paste with a relative density of 1.05 (60°C), dry under reduced pressure, grind into fine powder, add appropriate amount of dextrin...

Embodiment 2

[0033] Example 2: 5 parts of astragalus, 5 parts of sweet potato vine, 2 parts of Eclipta, 3 parts of Selaginella charcoal, 0.5 part of Panax notoginseng, 0.8 part of peanut shell, 2 parts of licorice

[0034] The above 8 flavors, 4 flavors of Astragalus, Ligustrum lucidum, Eclipta, Panax notoginseng were refluxed and extracted 6 times with 30% ethanol, and the amount of alcohol added was 10 times, 8 times, 8 times, 6 times and 4 times respectively amount, 3 times the amount, the extraction time is 1 hour, combine the extracts, filter, recover the ethanol from the filtrate and concentrate it properly, and use the concentrated solution for later use; add 12 times the amount of water to decoct sweet potato vines, Selaginella, peanuts, and licorice, and decoct Concentrate to 1:1, let cool, centrifuge, mix the supernatant with the above concentrate, filter, concentrate the filtrate properly, add appropriate amount of saccharin sodium, orange essence, potassium sorbate, Tween-80, st...

Embodiment 3

[0035] Example 3: 25 parts of Radix Astragali, 25 parts of Sweet Potato Vine, 10 parts of Eclipta, 17 parts of Selaginella, 3.5 parts of Panax notoginseng, 4.2 parts of peanut shell, 10 parts of licorice

[0036] The above 8 flavors, 4 flavors of Astragalus, Ligustrum lucidum, Eclipta, Panax notoginseng were reflux extracted with 80% ethanol for 3 times, the amount of alcohol added was 6 times, 5 times and 4 times respectively, and the extraction time was 4 hours respectively , 2 hours, and 1 hour, combine the extracts, filter, and reclaim ethanol from the filtrate and concentrate to a thick paste with a relative density of 1.02 to 1.05 for subsequent use; add 12, 10, Decoct 8 times the amount of water for 3 times, the time is 4 hours, 2 hours, and 1 hour respectively. The decoction is concentrated to 1:1, let it cool, and centrifuged. The supernatant is concentrated to a thick paste with a relative density of 1.1. The paste is mixed, dried, crushed, an appropriate amount of s...

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PUM

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Abstract

The invention relates to a drug for treating purpura. Raw materials to make effective components of the drug include radix astragali (prepared), sweet potato stem and leaf, ligustrum fruit, eclipta, elaginella (prepared), panax notoginseng, peanut sead-coat and liquorice. The raw materials can be made into various oral and external preparations through properly processing and/or acceptable auxiliary materials in pharmaceutics. With efficacies of Qi invigorating and Yin replenishing, and blood cooling and bleeding stopping, the invention is mainly used to treat purpura diseases caused by blood heat from Yin deficiency and Qi deficiency and blood absorbing failure, particularly mild and moderate thrombocytopenia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a medicine for purpura, in particular to a medicine containing traditional Chinese medicines such as astragalus, sweet potato vine, privet lucidum and the like. Background technique [0002] Thrombocytopenic purpura is a common hemorrhagic disease, which mostly occurs in children and young people, especially young women. The clinical manifestations are petechiae and ecchymosis on the skin, bleeding from the skin and mucous membranes, and even epistaxis, hematemesis, blood in the urine and stool, and internal bleeding. However, the etiology and pathogenesis of the disease have not been elucidated so far, and it is mostly considered to be a disease related to immunity, which is extremely difficult to treat. At present, western medicine treats thrombocytopenic purpura mainly with hormone therapy, such as adrenocortical hormones; immunosuppressants are also used, or combin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/00A61P7/04
Inventor 张保献
Owner 苏州弓正生物医药科技有限公司
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