70results about How to "High medicinal value" patented technology

The invention discloses preparation and application of lotus seed protein peptide with ACE (angiotensin converting enzyme) inhibitory activity, and belongs to the technical field of food-borne active peptide development. According to the ACE inhibitory peptide WVPRYFPF and the preparation method thereof, the ACE inhibitory peptide is rapidly screened by utilizing a polypeptiomics and molecular docking technology, the defects of time consumption and labor consumption caused by step-by-step separation and purification are avoided, the obtained ACE inhibitory peptide WVPRYFPF has extremely high ACE inhibitory activity, IC50 of the ACE inhibitory peptide WVPRYFPF is 16.7 mu M, and the ACE inhibitory peptide WVPRYFPF can be used for assisting or replacing hypertension drugs. The lotus seed protein peptide disclosed by the invention has the characteristic of inhibiting ACE enzyme activity in vitro, and animal experiments prove that the protein peptide can also play a role in lowering blood pressure in a spontaneous hypertension rat (SHR).

The invention belongs to the technical field of functional foods and health foods, and particularly relates to an anti-saccharification and anti-aging aronia melanocarpa fruit composition and a preparation method thereof. The composition is prepared from the following raw materials in parts by weight: 150 to 400 parts of aronia melanocarpa fruit fermentation liquor, 10 to 80 parts of lycium ruthenicum, 10 to 80 parts of ginseng, 0.5 to 2.5 parts of grape seed extract, 10 to 70 parts of collagen peptide, 0.5 to 4 parts of sodium hyaluronate, 0.1 to 0.8 part of resveratrol and 0.03 to 0.3 part of yeast extract. The content of type I collagen peptide in the skin is increased, the generation of in-vitro anti-glycation end products is inhibited, and the anti-glycation and anti-aging effects are achieved.

The invention belongs to the technical field of traditional Chinese medicines, and provides novel medical application of Chinese tamarisk twigs. The Chinese tamarisk twigs can be used for preparing medicines for preventing and treating hyperuricemia, and medicines for treating uric acid kidney stone, tophus or uric acid nephropathy caused by hyperuricemia. The invention also provides a preparation method of the Chinese tamarisk twig extract, which adopts water or / and ethanol for extraction. The new medical application of the Chinese tamarisk twigs is provided, the medical value of the Chinese tamarisk twigs is expanded, and compared with an existing uric acid reducing medicine allopurinol, the obtained extract can reduce the uric acid level of hyperuricemia, can inhibit rising of renal function indexes such as serum creatinine and urea nitrogen induced by hyperuricemia, improves liver and kidney tissue injuries, and has the advantages of being free of toxic and side effects, safe and reliable. The traditional Chinese medicine composition has the effect of improving liver and kidney functions and has good safety.

The invention relates to the technical field of vegetable planting, in particular to application of nano Mn3O4 in relieving vegetable salt stress and / or increasing the content of vegetable flavonoid compounds. The invention finds that nano Mn3O4 prepared by taking manganese acetate tetrahydrate as a manganese source not only can relieve salt stress of vegetables, but also can improve the content of flavonoid compounds in the vegetables, so that the nutritional value or medicinal value of the vegetables is improved. Furthermore, nano Mn3O4 is sprayed on vegetable leaves under salt stress, so that the salt stress of vegetables is relieved, and the content of flavonoid compounds in the vegetables is increased. According to the method provided by the invention, the physiological indexes of the vegetables are improved, the flavone content is increased, the influence of salt stress on the vegetables is relieved, and the method is a simple, effective and environment-friendly method for relieving the salt stress of the vegetables.

The invention belongs to the technical field of food biology, and particularly relates to an antioxidant peptide derived from cantharellus cibarius sporocarp, an antioxidant peptide detection reagent and application, and the amino acid sequence of the antioxidant peptide is at least one of FPYPY, YPPYF, YYPF and MPWY. The antioxidant peptide provided by the invention is derived from chanterelle, is an enzymolysis product of chanterelle protein, and is derived from edible and medicinal fungus chanterelle, so that the antioxidant peptide is small in toxic and side effects and high in safety. Meanwhile, the antioxidant peptide disclosed by the invention has good biological activity and a relatively strong antioxidant effect, can remarkably scavenge free radicals, and can be applied to repair damage caused by oxidative stress.

The invention discloses epigallocatechin gallate starch nanoparticles as well as a preparation method and application thereof, and belongs to the technical field of medicinal chemistry. According to the method, high-proportion branched-chain cassava starch is used as a raw material, ultrasonic microwave assistance is adopted, in the nanometer starch alcohol precipitation process, epigallocatechin gallate is synchronously packaged to form nanometer-level epigallocatechin gallate starch nanometer particles, and embedding of epigallocatechin gallate is completed. The embedding rate of the epigallocatechin gallate starch nanoparticles can reach 50.20%, the drug loading capacity can reach 311mg / g, the drug slow release performance is obvious in the process of simulating gastrointestinal digestion, the sustained release time can be 20 hours, the drug release capacity can reach 72.33% and 90.10% respectively, and the preparation process is simple, easy to operate, low in preparation cost and suitable for large-scale production and application.

The invention relates to the technical field of functional food production through microbial fermentation, in particular to a herba epimedii enzymolysis probiotic fermentation refined extract and a preparation method thereof.The preparation method comprises the following steps that herba epimedii and beta-cyclodextrin are mixed, an obtained mixed solution is subjected to enzymolysis treatment through pectinase, cellulase and glycosidase and then serves as a solid-state fermentation substrate, and the herba epimedii enzymolysis probiotic fermentation refined extract is obtained; adding mixed bacteria of lactobacillus casei, bifidobacterium lactis and lactobacillus gasseri, performing solid-state fermentation, and performing vacuum freeze drying to obtain a herba epimedii probiotic fermentation refined extract; the herba epimedii probiotic fermentation refined extract is prepared by adopting an enzymolysis fermentation method in cooperation with a beta-cyclodextrin inclusion technology, the extraction efficiency, the solubility, the biological activity, the stability and other performance of effective components in herba epimedii are improved, the preparation method is simple, and operation is easy and convenient; the used materials are edible, green and safe; the process saves energy consumption, has good environmental benefits, greatly saves manpower and material resources, and can be applied to industrial large-scale production.

The invention belongs to the technical field of edible and medicinal fungus development, particularly discloses a Ganoderma lucidum strain and a mycelium culture method thereof, particularly provides a Ganoderma lucidum strain ZHM1939 with the preservation number of CGMCC No: 41412, and provides the Ganoderma lucidum strain and the optimal culture method thereof for the first time. A new material is provided for research and clinical application of edible and medicinal values of ganoderma fungi, an excellent strain is provided for artificial cultivation, popularization and application of the ganoderma fungi, cultivable varieties of ganoderma are enriched, planting resources of ganoderma heterodermatum are effectively protected, and abbreviated threats of the ganoderma fungi caused by human factors and natural factors are prevented.

The invention belongs to the technical field of fungus molecular biology, and particularly relates to a beauvericin synthesis regulatory gene CcWC-1 and application thereof. The nucleotide sequence of the beauveria bassiana synthesis regulation gene CcWC-1 is as shown in SEQ ID NO. 1. The invention provides the cordyceps sobolifera CcWC-1 gene related to regulation and control of beauveria bassiana synthesis as well as the encoded protein and application thereof for the first time. By constructing a CcWC-1 gene knockout strain, the result shows that compared with a wild strain, the content of beauveria bassiana in the knockout strain is remarkably changed. Under an illumination culture condition, the beauveria bassiana content of the CcWC-1 knockout strain is obviously higher than that of a wild type. The invention discloses a regulation and control mechanism of illumination on the synthesis of the beauveria bassiana, provides a new gene resource and a production strategy for the artificial efficient production of the beauveria bassiana, and is beneficial to improving the yield of the beauveria bassiana.

The invention relates to the technical field of environment regulation and control, and particularly discloses an isatis root growth environment assessment regulation and control method and system based on multi-dimensional analysis, and the method comprises the steps: carrying out the height layering of a to-be-assessed isatis root subordinate growth space through a preset layering height, and obtaining each layer of growth space; according to the method, the growth environment of the isatis root in each layer of growth space is monitored, so that the isatis root in each layer can obtain the optimal growth condition, and meanwhile, a leaf environment temperature adaptive value and a leaf environment temperature influence value are matched by accurately evaluating and regulating multi-dimensional environment influence factors, so that the optimal growth condition of the isatis root in each layer is obtained. According to the method disclosed by the invention, the optimal growth environment temperature of the radix isatidis is finally judged and regulated by comprehensively comparing and analyzing with the obtained actual environment temperature value of the leaves, so that the yield and the quality of the radix isatidis growing in the controllable optimal growth environment can be greatly improved, the medicinal components and the medicinal value of the radix isatidis are improved, and the efficient utilization of resources is realized.

The invention belongs to the technical field of food processing, and particularly relates to rhizoma polygonati crisp chips and a preparation method thereof. The invention provides a pretreatment method of polygonatum sibiricum. The pretreatment method comprises the following steps: pretreating polygonatum sibiricum by utilizing steaming and drying circulation; the steaming time is 2 to 4 hours, and the steaming temperature is 90 to 110 DEG C; the drying temperature ranges from 40 DEG C to 50 DEG C, and the drying time ranges from 1.5 h to 2 h. The pretreatment method is simple to operate and low in cost, nutritional ingredients such as polysaccharide, saponin, flavone and polyphenol can be effectively reserved, and the prepared rhizoma polygonati crisp chips are crisp in taste, easy to chew and free of irritation.

This invention relates to a Rhodiola rosea pectin polysaccharide for improving sleep and its application, belonging to the field of pharmaceutical technology. This Rhodiola rosea pectin polysaccharide is extracted and purified from Rhodiola rosea using a water extraction and alcohol precipitation method. It can effectively improve sleep, is safe and reliable, and has high medicinal value.

The present invention provides an aminoalkoxy modified flavonoid compound having a structure shown in Formula I or a salt thereof. The present invention mainly uses aminoalkoxy to modify the side chain of flavonoid without changing the parent nucleus of flavonoid itself, and synthesizes a series of small molecule compounds with flavonoid compounds as the skeleton. Compared with the parent nucleus itself, the series of compounds retains the advantage of low toxicity of flavonoids to normal cells, while the anti-tumor activity is significantly improved, and the solubility is significantly improved.

The invention discloses application of vitexin (the molecular formula of the vitexin is C19H18O8, the molecular weight of the vitexin is 374.34, and the CAS number of the vitexin is 479-91-4) in preparation of antitumor drugs. The method comprises the following steps: firstly, treating esophageal cancer cell lines KYSE70 and KYSE450 with vitexin, detecting cell proliferation conditions after 0, 24 hours, 48 hours and 72 hours, and determining that the vitexin has an inhibiting effect on the esophageal cancer cell lines; the vitexin can inhibit cell proliferation of skin cancer cell lines SK-MEL-5 and SK-MEL-28 and ovarian cancer cell lines SKOV3 and TOV112D under the same concentration, and compared with a control group, the growth speed of tumor cells is remarkably reduced along with increase of the concentration of the vitexin, so that the vitexin has a remarkable effect on treating esophageal cancer, skin cancer and ovarian cancer; secondly, through a Pull down experiment, it is found that vitexin targets PRDX1, and it is indicated that vitexin can inhibit proliferation of tumor cells in vivo and in vitro by targeting PRDX1.

A flowerpot body (1) is provided with at least one larger planting hole (2) communicated with a smaller water permeable hole (3), and the overlook projection area of an aerial root attachment platform (5) on the periphery of the planting hole (2) is obviously larger than that of the planting hole (2). The environment of the platform (5) is moist, the dendrobe (8) is rapidly induced to grow white aerial roots (4), and the aerial roots (4) are fixed on the steamed bun-shaped red platform (5), extend in a radial shape, extend all around, are like lightning and are sky-spectacular, strong vitality is shown, and the ornamental value of the potted dendrobe is greatly improved.

The application discloses a vehicle-mounted snake venom processing device and a method for processing snake venom by using the same. The vehicle-mounted snake venom processing device comprises a vehicle body, a workbench and a power supply device arranged in the vehicle body, and the workbench is provided with a separation device, a drying device, a detection device and a storage device. The drying device comprises a vehicle-mounted freeze dryer and an oil-free vacuum pump, and the crude snake venom separated by the separation device is subjected to freeze drying to obtain freeze-dried snake venom powder. The detection device comprises one or more of an enzyme label instrument, an ultraviolet spectrophotometer and a moisture tester for detecting biochemical indexes of the freeze-dried snake venom powder. The storage device is used for storing the freeze-dried snake venom powder which passes the detection. The vehicle-mounted snake venom processing device has a compact structure and is convenient to move and use, is suitable for collecting and processing snake venom in the scattered snake breeding of present snake breeders, significantly shortens the snake venom processing time, effectively retains active ingredients of the snake venom, improves the medicinal value of the snake venom, and is favorable for classified storage of the snake venom through on-site detection and analysis.

The invention discloses a method for extracting active polysaccharides from Chinese wolfberry residues through compound microorganism fermentation. Relates to the technical field of microbial fermentation. Extraction methods and uses are provided. The method for extracting the lycium barbarum polysaccharide through the water extraction and alcohol precipitation method combined with the compound microorganism fermentation pretreatment has the advantages of being high in extraction efficiency, easy to operate and low in cost. The high-purity lycium barbarum polysaccharide can be obtained through subsequent deproteinization and refining purification steps. Meanwhile, the technological processes of multiple links are optimized and integrated, the use of solvents and the energy consumption are greatly reduced, and the production concept of green and environment-friendly is met. The biological activity of the polysaccharide subjected to biological fermentation is effectively improved, and the polysaccharide has relatively high medicinal value and market application prospect.

The invention provides a processing method of traditional Chinese medicine pinellia ternate, which comprises the following steps: processing 5-200kg of fresh pinellia ternate or raw pinellia ternate by adopting a microwave processing technology, and carrying out microwave drying in industrial microwave equipment at 40-80 DEG C and 2-60kw until the water content of the pinellia ternate is lower than 12%, so as to obtain the processed traditional Chinese medicine pinellia ternate. According to the processing method of the medicinal material pinellia ternate, the processing period of the pinellia ternate within 9-11 days can be shortened to 30-90 minutes, the processing efficiency of the pinellia ternate is obviously improved, and the processing period is shortened; irritation is reduced, the retention rate of effective components is higher, and the medicinal value and curative effect of the medicine are improved; and no wastewater or waste gas is generated in the processing process, so that the energy consumption is reduced, and the production cost is reduced.

The invention discloses mushroom and lucid ganoderma wine and a brewing method thereof.The mushroom and lucid ganoderma wine is prepared from 260-300 kg of rice wine, 430-470 kg of distilled liquor, 6-12 kg of mushrooms, 1-5 kg of lucid ganoderma, 2-7 kg of milkvetch roots, 2-7 kg of Chinese wolfberry fruits, 1-5 kg of mulberries, 6-12 kg of cistanche deserticola and 250-300 kg of cold boiled water according to 1000 kg of finished products. The lentinus edodes and lucid ganoderma wine brewed by the method integrates the effects of various medicinal and edible food materials such as the sticky rice, the lentinus edodes, the lucid ganoderma and the astragalus membranaceus, and has relatively high nutritional and medicinal values; the effects of resisting cancer, enhancing human immunity, tonifying qi, soothing the nerves, relieving cough and asthma, supporting healthy energy, protecting the liver, resisting fatigue, delaying senescence, reducing blood sugar, promoting circulation, expanding blood vessels, reducing blood cholesterol and triglyceride and the like can be achieved.

The invention relates to the technical field of wine-processed rhizoma polygonati, and particularly discloses a preparation process of wine-processed rhizoma polygonati. The preparation process of the wine rhizoma polygonati comprises the following steps: adding rhizoma polygonati slices into water, moistening, and taking out to obtain moistened rhizoma polygonati; cooling, standing, heating, standing and drying the moistened polygonatum sibiricum in the sun to obtain freeze-thawed polygonatum sibiricum; adding the freeze-thawed rhizoma polygonati into the yellow wine-water mixed solution, moistening, and taking out to obtain moistened wine rhizoma polygonati; cooling, standing, heating and standing the moistened wine polygonatum sibiricum to obtain freeze-thawed wine polygonatum sibiricum; and steaming the freeze-thawed wine rhizoma polygonati for multiple times, and drying in the sun for multiple times to obtain nine-steamed nine-sun-dried wine rhizoma polygonati. The nine-steamed nine-sun-dried wine rhizoma polygonati obtained by the preparation process has the advantages of high water-soluble extract content, high total polysaccharide content and high total saponin content, shows excellent medicinal value, and meets market requirements.

This invention discloses a method for preparing and applying crude and homogeneous polysaccharides of *Mesona chinensis* that regulate *Bacteroides*. The method includes the following steps: pulverizing *Mesona chinensis* herb, extracting by reflux with deionized water, filtering out the residue, concentrating to 1 / 4 of the volume, adding ethanol to 80% by volume, stirring evenly, letting stand overnight, centrifuging the precipitate, washing three times with anhydrous ethanol, ethyl acetate, and acetone respectively, dissolving in an appropriate amount of deionized water, and freeze-drying to obtain crude *Mesona chinensis* polysaccharide. The obtained crude *Mesona chinensis* polysaccharide is diluted with deionized water and dialyzed using dialysis bags in the range of 7000D, 100000D, 300000D, and 500000D respectively. The solutions are combined, concentrated, and freeze-dried to obtain homogeneous polysaccharides of *Mesona chinensis* with different molecular weights. The prepared crude and homogeneous polysaccharides of *Mesona chinensis* have good antioxidant capacity and can promote the growth of *Bacteroides* in the gut. In vitro experiments verified that the metabolites of *Mesona chinensis* polysaccharide have good lipid-lowering activity.

The invention provides a pharmaceutical composition aiming at mcr positive drug-resistant bacteria and application of the pharmaceutical composition, and belongs to the technical field of biomedicine. The composition is composed of patchouli alcohol and polymyxin B or polymyxin E, and the antibacterial effect on mcr positive drug-resistant bacteria is remarkably enhanced. Experimental results show that when patchouli alcohol and polymyxin B or E are combined for use, the minimum inhibitory concentration (MIC) of polymyxin can be remarkably reduced, and the FIC is less than 0.5, so that the patchouli alcohol and the polymyxin B or E have a synergistic effect. In addition, a cytotoxicity experiment shows that patchouli alcohol has no obvious toxicity to normal cells in a certain concentration range and has relatively high safety. The composition can be used as a synergistic enhancer of polymyxin, can effectively cope with mcr positive drug-resistant bacterial infection, provides a safe and efficient new way for treatment of drug-resistant bacterial infection, and is helpful for delaying the progress of antibiotic drug resistance crisis.

The invention discloses a use of a tetrahydrofuran lignan compound. The tetrahydrofuran lignan compound is a monotetrahydrofuran lignan compound having a chemical structure shown in formula I: or a ditetrahydrofuran lignan compound having a chemical structure shown in formula II:; the use refers to using the tetrahydrofuran lignan compound or at least one of its stereoisomers, precursor compounds, deuterated substances, and pharmaceutically acceptable esters as an active ingredient for preparing a phosphodiesterase 4 inhibitor, which is further expected to be used as an active ingredient for preparing a drug for preventing and / or treating related diseases mediated by phosphodiesterase 4 and preparing a cosmetic for improving skin sensitivity, and has broad application prospects.

The invention belongs to the technical field of medicinal chemistry, and particularly relates to a tripterine-platinum (IV) complex with antitumor activity as well as a preparation method and application of the tripterine-platinum (IV) complex. The tripterine-platinum (IV) complex takes tripterine as an axial ligand, and a platinum center skeleton structure is cis-platinum, carboplatin or oxaliplatin. The tetravalent platinum complex can induce para-apoptosis of cancer cells, so that the common problem of drug resistance caused by apoptosis resistance of the cancer cells in tumor chemotherapy is solved. Besides, the tetravalent platinum complex has the characteristics of high efficiency and low toxicity, the in-vitro cytotoxicity of the tetravalent platinum complex to tumor cells such as non-small cell lung cancer A549 cells and cisplatin-resistant strains A549cisR thereof is higher than that of clinically applied metal anti-cancer drug cisplatin, and the tetravalent platinum complex has low toxicity to normal cells MRC-5, so that the tetravalent platinum complex has a good application prospect. Good selectivity and relatively high medicinal value are shown in the aspect of inhibiting the growth of tumor cells.

The application discloses a gene of eudesmolsynthase AoTPS1 and an application of the gene and a coded protein, and provides a gene AoTPS1 for regulating biosynthesis of a monoterpenoid compound eudesmol, wherein a nucleotide sequence is shown as SEQ ID NO. 1, the total length of the sequence is 1785 bp, 594 amino acids are coded, the molecular weight is 69.03 kDa, and a coded amino acid sequence is shown as SEQ ID NO. 2. The eudesmolsynthase AoTPS1 protein has the function of catalyzing synthesis of eudesmol in vitro, meanwhile, overexpression of the eudesmolsynthase AoTPS1 gene by using a genetic transformation technology can significantly increase the content of eudesmol in monoterpenoid volatile oil compounds. Therefore, the AoTPS1 gene is a key gene for regulating synthesis of volatile oil of Eucommia ulmoides Oliv., and can significantly promote biosynthesis of eudesmol in monoterpenoid volatile oil and improve the medicinal value of volatile oil of Eucommia ulmoides Oliv.

The invention relates to the technical field of agricultural product processing, in particular to a preparation method of prinsepia utilis royle tea, which comprises the steps of prinsepia utilis royle bud harvesting, primary inspection, cleaning, baking, reinspection, fragrance extraction, fumigation and redrying. The preparation method comprises the following steps: harvesting, primarily inspecting and cleaning to ensure the purity of the raw materials, then baking flower buds, spreading for cooling, primarily drying and retaining aroma, after reinspection, heating, stir-frying, enhancing aroma, spreading for cooling again, then loading into a Chinese toon big steamer for fumigating to further improve the aroma and flavor, and finally, rebaking, ensuring thorough drying and spreading for cooling to obtain the prinsepia utilis royle tea. Therefore, purity and no pollution of the raw materials are guaranteed, drying and aroma enhancing processes are optimized, aroma and flavor of the tea leaves are improved, natural characteristics of the tea leaves are kept, consistency and stability of products are improved, and quality of the prinsepia utilis royle tea is improved.

The invention discloses an oral soluble film composition containing vardenafil and application of the oral soluble film composition. The oral soluble film composition comprises the following components in percentage by weight: 20.5%-25% of an active substance, 28.3%-32% of microcrystalline cellulose, 2.6%-3.3% of vitamin E, 1.5%-2.1% of a separant, 0.8%-1.1% of a lubricant, 35.6%-41.5% of a film forming material, 1.2%-1.8% of a plasticizer, 0.08%-0.12% of a pH regulator and 2.7%-3.5% of a flavoring agent, the active substance is vardenafil or vardenafil hydrochloride, the concentration of the active substance is 35-45 mg / ml, and the oral soluble film composition is applied to improving the erectile function, prolonging the sexual life time, improving the microenvironment of local spermatogenesis and improving the sperm vitality. The pH regulator is matched, so that the dissolution speed of the medicine can be increased; 40-60 hydroxypropyl methyl cellulose and polyvinyl alcohol are blended to form a film material, so that the film coating effect can be ensured, and the properties of the film can be improved; vitamin E is added in the formula, so that the microenvironment of local spermatogenesis can be improved, the sperm motility is improved, and the medicinal value of the composition is improved.

The invention provides an antibacterial peptide for resisting acinetobacter baumannii, which is a) a polypeptide with an amino acid sequence of SEQ ID NO: 1 (KRIXRRIXIFLR), or b) a derivative peptide obtained by replacing and / or deleting and / or adding 1-5 amino acid residues on the polypeptide with the amino acid sequence of SEQ ID NO: 1, wherein X is Fmoc-S < 5 >-OH total hydrocarbon stapled amino acid. The invention also provides a preparation method and application of the antibacterial peptide. The protease degradation tolerant derivative is screened out through total hydrocarbon stapled amino acid replacement and structure-effect relationship research, and the protease degradation tolerant derivative is easy to prepare, high in biological safety and good in clinical application prospect.

The invention relates to the technical field of artificial cultivation of medicinal fungi, and discloses a cultivation method of ganoderma lucidum spore powder with high triterpenoid polysaccharide content, which comprises the following steps: S1, inoculating a ganoderma lucidum strain in a seed solution culture medium, and culturing to obtain a seed solution; s2, inoculating the seed solution to a fermentation culture medium, and culturing to obtain a fermentation solution; s3, carrying out oscillation-standing circulation culture on the fermentation liquid, and separating the bacterial liquid to obtain mycelia; s4, inoculating the mycelium into a cultivar culture medium for culturing to obtain a ganoderma lucidum cultivar; s5, transplanting ganoderma lucidum cultivated species on the substitute culture medium, and culturing to obtain ganoderma lucidum; s6, the ganoderma lucidum is sleeved with a net cover, and ganoderma lucidum spore powder is collected. The content of triterpenes and polysaccharides in the ganoderma lucidum spore powder can be increased.

The invention relates to the technical field of medical engineering, and discloses a nampt-rich wound repair exosome hydrogel and a preparation method thereof.The preparation method comprises the following preparation steps that mesenchymal stem cells are adopted to extract exosomes, and mesenchymal stem cell exosomes are obtained; the preparation method comprises the following steps: mixing and reacting nampt, astragaloside, medium chain triglyceride and soybean phospholipid to obtain lipid nanoparticles; mixing the lipid nanoparticles with the mesenchymal stem cell exosome to obtain an exosome loaded with the lipid nanoparticles; mixing the exosome loaded with the lipid nanoparticles, a cabbage extract and a polysaccharide extract to obtain a compound; the compound, a chitosan solution and a beta-sodium glycerophosphate solution are mixed, and the wound repair exosome hydrogel rich in nampt is obtained. The loaded lipid nanoparticles, the cabbage extract and the polysaccharide extract are compounded to serve as a wound repairing medicine, and the wound repairing medicine is added into the hydrogel to serve as a wound repairing agent, so that the wound repairing capacity can be effectively improved.