18results about How to "High medicinal value" patented technology

The invention relates to the technical field of functional food production through microbial fermentation, in particular to a herba epimedii enzymolysis probiotic fermentation refined extract and a preparation method thereof.The preparation method comprises the following steps that herba epimedii and beta-cyclodextrin are mixed, an obtained mixed solution is subjected to enzymolysis treatment through pectinase, cellulase and glycosidase and then serves as a solid-state fermentation substrate, and the herba epimedii enzymolysis probiotic fermentation refined extract is obtained; adding mixed bacteria of lactobacillus casei, bifidobacterium lactis and lactobacillus gasseri, performing solid-state fermentation, and performing vacuum freeze drying to obtain a herba epimedii probiotic fermentation refined extract; the herba epimedii probiotic fermentation refined extract is prepared by adopting an enzymolysis fermentation method in cooperation with a beta-cyclodextrin inclusion technology, the extraction efficiency, the solubility, the biological activity, the stability and other performance of effective components in herba epimedii are improved, the preparation method is simple, and operation is easy and convenient; the used materials are edible, green and safe; the process saves energy consumption, has good environmental benefits, greatly saves manpower and material resources, and can be applied to industrial large-scale production.

This invention relates to a Rhodiola rosea pectin polysaccharide for improving sleep and its application, belonging to the field of pharmaceutical technology. This Rhodiola rosea pectin polysaccharide is extracted and purified from Rhodiola rosea using a water extraction and alcohol precipitation method. It can effectively improve sleep, is safe and reliable, and has high medicinal value.

A flowerpot body (1) is provided with at least one larger planting hole (2) communicated with a smaller water permeable hole (3), and the overlook projection area of an aerial root attachment platform (5) on the periphery of the planting hole (2) is obviously larger than that of the planting hole (2). The environment of the platform (5) is moist, the dendrobe (8) is rapidly induced to grow white aerial roots (4), and the aerial roots (4) are fixed on the steamed bun-shaped red platform (5), extend in a radial shape, extend all around, are like lightning and are sky-spectacular, strong vitality is shown, and the ornamental value of the potted dendrobe is greatly improved.

The application discloses a vehicle-mounted snake venom processing device and a method for processing snake venom by using the same. The vehicle-mounted snake venom processing device comprises a vehicle body, a workbench and a power supply device arranged in the vehicle body, and the workbench is provided with a separation device, a drying device, a detection device and a storage device. The drying device comprises a vehicle-mounted freeze dryer and an oil-free vacuum pump, and the crude snake venom separated by the separation device is subjected to freeze drying to obtain freeze-dried snake venom powder. The detection device comprises one or more of an enzyme label instrument, an ultraviolet spectrophotometer and a moisture tester for detecting biochemical indexes of the freeze-dried snake venom powder. The storage device is used for storing the freeze-dried snake venom powder which passes the detection. The vehicle-mounted snake venom processing device has a compact structure and is convenient to move and use, is suitable for collecting and processing snake venom in the scattered snake breeding of present snake breeders, significantly shortens the snake venom processing time, effectively retains active ingredients of the snake venom, improves the medicinal value of the snake venom, and is favorable for classified storage of the snake venom through on-site detection and analysis.

The invention discloses mushroom and lucid ganoderma wine and a brewing method thereof.The mushroom and lucid ganoderma wine is prepared from 260-300 kg of rice wine, 430-470 kg of distilled liquor, 6-12 kg of mushrooms, 1-5 kg of lucid ganoderma, 2-7 kg of milkvetch roots, 2-7 kg of Chinese wolfberry fruits, 1-5 kg of mulberries, 6-12 kg of cistanche deserticola and 250-300 kg of cold boiled water according to 1000 kg of finished products. The lentinus edodes and lucid ganoderma wine brewed by the method integrates the effects of various medicinal and edible food materials such as the sticky rice, the lentinus edodes, the lucid ganoderma and the astragalus membranaceus, and has relatively high nutritional and medicinal values; the effects of resisting cancer, enhancing human immunity, tonifying qi, soothing the nerves, relieving cough and asthma, supporting healthy energy, protecting the liver, resisting fatigue, delaying senescence, reducing blood sugar, promoting circulation, expanding blood vessels, reducing blood cholesterol and triglyceride and the like can be achieved.

This invention discloses a method for preparing and applying crude and homogeneous polysaccharides of *Mesona chinensis* that regulate *Bacteroides*. The method includes the following steps: pulverizing *Mesona chinensis* herb, extracting by reflux with deionized water, filtering out the residue, concentrating to 1 / 4 of the volume, adding ethanol to 80% by volume, stirring evenly, letting stand overnight, centrifuging the precipitate, washing three times with anhydrous ethanol, ethyl acetate, and acetone respectively, dissolving in an appropriate amount of deionized water, and freeze-drying to obtain crude *Mesona chinensis* polysaccharide. The obtained crude *Mesona chinensis* polysaccharide is diluted with deionized water and dialyzed using dialysis bags in the range of 7000D, 100000D, 300000D, and 500000D respectively. The solutions are combined, concentrated, and freeze-dried to obtain homogeneous polysaccharides of *Mesona chinensis* with different molecular weights. The prepared crude and homogeneous polysaccharides of *Mesona chinensis* have good antioxidant capacity and can promote the growth of *Bacteroides* in the gut. In vitro experiments verified that the metabolites of *Mesona chinensis* polysaccharide have good lipid-lowering activity.

The application discloses a gene of eudesmolsynthase AoTPS1 and an application of the gene and a coded protein, and provides a gene AoTPS1 for regulating biosynthesis of a monoterpenoid compound eudesmol, wherein a nucleotide sequence is shown as SEQ ID NO. 1, the total length of the sequence is 1785 bp, 594 amino acids are coded, the molecular weight is 69.03 kDa, and a coded amino acid sequence is shown as SEQ ID NO. 2. The eudesmolsynthase AoTPS1 protein has the function of catalyzing synthesis of eudesmol in vitro, meanwhile, overexpression of the eudesmolsynthase AoTPS1 gene by using a genetic transformation technology can significantly increase the content of eudesmol in monoterpenoid volatile oil compounds. Therefore, the AoTPS1 gene is a key gene for regulating synthesis of volatile oil of Eucommia ulmoides Oliv., and can significantly promote biosynthesis of eudesmol in monoterpenoid volatile oil and improve the medicinal value of volatile oil of Eucommia ulmoides Oliv.

The invention relates to the technical field of artificial cultivation of medicinal fungi, and discloses a cultivation method of ganoderma lucidum spore powder with high triterpenoid polysaccharide content, which comprises the following steps: S1, inoculating a ganoderma lucidum strain in a seed solution culture medium, and culturing to obtain a seed solution; s2, inoculating the seed solution to a fermentation culture medium, and culturing to obtain a fermentation solution; s3, carrying out oscillation-standing circulation culture on the fermentation liquid, and separating the bacterial liquid to obtain mycelia; s4, inoculating the mycelium into a cultivar culture medium for culturing to obtain a ganoderma lucidum cultivar; s5, transplanting ganoderma lucidum cultivated species on the substitute culture medium, and culturing to obtain ganoderma lucidum; s6, the ganoderma lucidum is sleeved with a net cover, and ganoderma lucidum spore powder is collected. The content of triterpenes and polysaccharides in the ganoderma lucidum spore powder can be increased.

The present application relates to a kind of yunnan ganoderma strain HL45 and its cultivation method and application, belong to the field of microbial technology.The strain has been preserved in Guangdong Provincial Microbial Culture Collection Center on September 11, 2024, and the preservation number is GDMCC No:65119.The present application yunnan ganoderma strain HL45 fruiting body presents single or multi-branch, cap purple brown, flesh white, and stable in character;The content of triterpenoid ganoderol F and glucosan polysaccharide is very high, which can be used for preparing antitumor drugs.In addition, the fruiting body of the strain has strong mushroom aroma, and the quality of the whole mushroom is good.The average growth cycle of cultivation bag is 26d, the mycelial growth rate is 0.78cm / d, the average yield is 16.62g / bag, the highest biological efficiency reaches 10.26%, the cultivation period is about 4-5 months, and it is suitable for cultivation in high-altitude areas above 2000m, with high ornamental and application value.

The application provides a rhizome traditional Chinese medicinal material cleaning device. The device comprises a vibration cleaning mechanism and a brushing mechanism. The vibration cleaning mechanism comprises a box body and a polarization cleaning part arranged at the bottom of the box body. The polarization cleaning part is used for controlling the vibration of the box body to clean the medicinal materials in the box body. The box body comprises a discharge port, and a first closing door is arranged at the discharge port. The brushing mechanism comprises a spraying part, a brushing part and a cleaning table. The cleaning table is connected with the discharge port of the box body and is fixedly connected with the ground. The spraying part is used for spraying and flushing the medicinal materials on the cleaning table, and the brushing part is used for brushing and cleaning the medicinal materials on the cleaning table. The spraying part comprises a plurality of spraying units, and the brushing part comprises a plurality of brushing units. The spraying units and the brushing units are arranged at intervals. The device can avoid the damage of the medicinal materials during the cleaning process, fully clean the soil in the uneven gap on the surface of the medicinal materials, ensure the cleaning effect and the medicinal effect of the medicinal materials.

The application discloses a kind of purification enrichment methods of anti-cancer roselle juice biological preparation freeze-dried powder, belong to biological preparation technical field.The method uses natural ripening, no sugar, no concentrated roselle original juice as raw material, adopts ≤45 ℃ low temperature operation throughout, steps include 300 mesh high pressure filtration, low temperature centrifugation, 0.22 μm ceramic membrane precision filtration, 30kDa ultrafiltration, 3kDa ultrafiltration, 300Da nanofiltration, RO pre-concentration coupling polyamide-anion exchange resin fractionation monosaccharide, vacuum concentration, freeze-drying, quality control;The method is separated by molecular weight gradient and combined with selective adsorption of resin, the removal rate of monosaccharide and disaccharide in the raw material is increased to more than 98%, while the retention rate of VC, SOD, flavone, tannin and other anti-cancer active ingredients of roselle is not less than 90%;The yield of finished product is controlled at 4.0%~8.0%, the whole set of process membrane pollution is light, production is coherent and stable, suitable for large-scale production.The obtained freeze-dried powder is high in purity and good in stability, and can be used as anti-cancer biological raw material or compounded with clinical anti-cancer drugs.

The application belongs to the technical field of natural compounds, and particularly relates to a natural Rakicidins compound Rakicidin K and a fermentation extraction method thereof. The Rakicidins analogue Rakicidin K is a novel compound isolated and extracted from fermentation liquor of a mutant strain FIM-R150103 of Micromonospora. The cytotoxic activity of the Rakicidins analogue Rakicidin K is further evaluated and verified. The activity results show that the natural compound Rakicidin K has strong in-vitro inhibition on human colon cancer cells HCT-8 and human pancreatic cancer cells PANC-1, has certain inhibition activity on various gram-positive bacteria, and has good biological activity and high medicinal value.

The invention discloses a nitro-substituted dihydroacridine spiroisoquinolinone compound as well as a synthesis method and anticancer activity thereof, and belongs to the technical field of organic synthesis and drug discovery. The method comprises the following steps: mixing an N-nitrosodiphenylamine compound 1, a diazoisoquinoline diketone compound 2, a catalyst, an additive and hexafluoroisopropanol, heating, and carrying out a one-pot cascade reaction to obtain the nitro-substituted dihydroacridine spiroisoquinolinone compound 3. Optimized screening and anti-cancer cell activity tests prove that the provided compound can obviously inhibit proliferation of two cancer cells, namely Hela and HCT-116, so that the compound has obvious anti-cancer activity on cervical cancer and colon cancer, and has potential medicinal value.

The invention belongs to the technical field of microbial fermentation, and particularly relates to a preparation method of an astragalus mongholicus fermentation product and application of the obtained astragalus mongholicus fermentation product in preparation of products for reducing blood sugar and blood fat and promoting absorption. The preparation method specifically comprises the following steps: (1) uniformly mixing radix astragali powder with water, and sterilizing to obtain a radix astragali aqueous solution; and (2) inoculating strains into the radix astragali aqueous solution, and carrying out ultrasonic-assisted fermentation, so as to obtain the radix astragali fermented product. The obtained astragalus mongholicus fermentation product has strong active hydroxyl free radical scavenging rate, iron ion reducing capacity and ABTS < + > free radical scavenging rate; the activity of inhibiting alpha-glucosidase, DPP-IV (dipeptidyl peptidase-IV) and pancreatic lipase is better; the content release of calycosin, total polyphenols and total flavonoids in the intestinal digestion process can be obviously improved.