6 results about "Schaftoside" patented technology

The invention relates to the technical field of pharmaceutical preparations, in particular to a stable desonide lotion and a preparation method thereof. The desonide lotion is prepared from the following components in percentage by weight: 0.5 to 1.2 percent of desonide, 0.2 to 0.6 percent of a functional additive, 2 to 6 percent of span 80, 1 to 3 percent of dimethyl silicone oil, 2 to 5 percent of glycerol, 2 to 3 percent of asiaticoside, 3 to 6 percent of glycerol monostearate, 2 to 3 percent of squalane, 3 to 5 percent of tragacanth, 0.5 to 1 percent of fumed silica, 0.05 to 0.1 percent of tartaric acid, 0.08 to 0.12 percent of citric acid, 2 to 4 percent of a wetting agent, 0.08 to 0.2 percent of a preservative, 0.2 to 0.5 percent of an antioxidant and the balance of water. According to the functional additive prepared by a specific method, a porous titanium dioxide ball is used as a carrier, and a norfloxacin derivative is bonded on the surface and in a pore channel of the porous titanium dioxide ball through a photochemical grafting technology; the use of the functional additive effectively improves the antibacterial property and photosensitivity of the desonide lotion, so that the prepared desonide lotion not only is highly stable, but also has anti-inflammatory and antibacterial effects, is excellent in comprehensive performance, and has very high market application value.

The application discloses a kind of based on yeast metabolic engineering's hydroxyl asiaticoside high-efficiency preparation method and its compound cosmetic composition.The application is screened from asiaticoside transcriptome CaGlcT1, CaGlcT2 and CaRhaT three glycosyltransferases, after verifying its catalytic activity, multi-gene co-expression is carried out in saccharomyces cerevisiae, and hydroxyl asiaticoside can be catalyzed to synthesize hydroxyl asiaticoside.The conversion yield of hydroxyl asiaticoside reaches 582mg / L from 165mg / L after fermentation condition optimization and batch feeding fermentation, realizes 3.5 times yield leap, obtains the purity of hydroxyl asiaticoside reaches more than 95%, satisfies commercial application and research demand.Hydroxyl asiaticoside obtained is compounded with golden yellow chamomile extract and spilanthes extract, and plays the synergistic antioxidant whitening effect.The application provides a new scheme for green intelligent manufacturing of cosmetic raw materials.

The invention discloses a preparation method of a compound lysimachia christinae hance preparation extract, which comprises the following steps: carrying out water extraction and alcohol precipitation on traditional Chinese medicinal materials to obtain a crude extract, and purifying the crude extract with macroporous resin. By screening and optimizing extraction and purification processes, the purity of target components is effectively improved, the daily taking amount of extracts is reduced, and on the premise that the transfer rate is basically kept, compared with an existing preparation process of a compound herba lysimachiae preparation, the purity of total flavonoids, schaftoside and mangiferin is remarkably improved, and a huge space is provided for preparation of the preparation.

The invention relates to medical cold compress gel for improving gout and a preparation method of the medical cold compress gel. The medical cold compress gel comprises the following components in percentage by weight: (1) a cooling matrix material: 0.5-2% of carbomer, 5-15% of glycerol and 3-8% of propylene glycol; (2) natural anti-inflammatory components: 1-3% of a radix scutellariae extract and 0.5-1.5% of asiaticoside; (3) a uric acid inhibitor: 0.2%-1% of apigenin nano-liposome and 0.1%-0.5% of chicoric acid; (4) a transdermal penetration enhancer: 1-3% of azone and 0.5-2% of menthol; and the balance of deionized water. The invention has the following beneficial effects: 1, physical-chemical synergistic effect: red and swollen can be relieved by cold compress, and inflammatory factors such as IL-1beta, TNF-alpha and the like can be inhibited by the active components; 2, targeted inhibition of uric acid: apigenin nano-liposome enhances transdermal absorption and inhibits the activity of xanthine oxidase; 3, the safety is high: the systematic side effects of the traditional medicine are reduced by the natural components;

This invention discloses a pharmaceutical composition for treating chapped skin caused by tinea pedis and manuum. The composition comprises urea, olive leaf extract, oat alkaloids, and asiaticoside as active ingredients, combined with a hypoallergenic liquid crystal emulsion matrix consisting of shea butter, squalane, caprylic / capric triglycerides, and cetearyl glucoside. This invention utilizes urea to soften keratin and promote crack healing, while simultaneously inhibiting the irritation caused by urea through the synergistic effect of three plant-based anti-inflammatory components, and combining biomimetic oils to repair the skin's lipid barrier. This composition significantly reduces pain and itching at the chapped areas in patients with tinea pedis and manuum, promotes crack closure, and avoids the burning and irritation commonly found in traditional antifungal ointments.

The application belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof. The anti-wrinkle and anti-aging composition comprises a neurotransmitter inhibitory peptide, a signal peptide, hydroxyl asperosaponin, myo-inositol and glycerol glucoside. The neurotransmitter inhibitory peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyroyl benzylamide diacetate and acetyl octapeptide-3, and the signal peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, the anti-wrinkle and anti-aging composition has the advantages that the components act on different anti-aging pathways, can cooperate with each other in terms of antioxidant, anti-inflammatory, moisturizing, enhanced cell vitality, reduced wrinkles and the like, can provide more comprehensive and better anti-aging effect, can comprehensively resist skin aging, and can make the skin appear more youthful, and the anti-wrinkle and anti-aging composition has small irritation and good stability.