53 results about "Chicken Pox" patented technology

Jojoba alcohol, a mixture of long chain monounsaturated alcohols, is an oily liquid at moderate ambient temperatures. It is readily absorbed by human skin where it relieves irritation and inhibits the formation of lesions caused by viruses. The inhibitory action is applicable to enveloped viruses which express as sores at dermal surfaces in humans. When applied topically to an incipent herpes episode, it will quickly penetrate the epidermis to the subdermal vascular cells and suppress viral replication which leads to inflammation and the formation of blisters on the face, genital and other skin and mucosal areas. Fumaric acid and malonic acid at low concentrations also inhibit the replication of varicella zoster virus in human cell cultures, with no cellular toxicity. Compositions of certain low molecular weight organic acids in jojoba alcohol enhance antiviral activity. Topical treatment of shingles with a low concentration of fumaric acid in jojoba alcohol terminates the episode. This combination drug acts by a dual mechanism wherein the jojoba alcohol blocks viral fusion by a lipoidal mode, and the polycarboxylic acids inhibit viral fusion by an ionic mode. The combination drug can also be effective in treating chicken pox. Jojoba alcohol is a carrier and transdermal delivery system for these and other pharmacologically active agents for the relief of pain and treatment of other conditions which occur at or under the surface of the skin. Topically applied jojoba alcohol is non-toxic and safe for animals and humans.

The present invention provides a freeze-dried hepatitis-A-chicken-pox attenuation combined vaccine and a production thereof. The combined vaccine has the security and the immunogenicity as good as the univalent vaccine and can effectively prevent the hepatitis A and the chicken pox. Two kinds of diseases can be effectively prevented just by one immunization, which can reduce vaccine cost, improve vaccine inoculation efficiency and reduce the bad reaction caused by a plurality of times of injections, and can reduce the vaccine inoculation times but realize the purpose of preventing various diseases.

The invention relates to a drug for treating chicken pox and a preparation method thereof, pertaining to the field of blood products. The technical problem solved by the invention is that: a drug which can effectively treat chicken pox is provided. The drug for treating chicken pox is a preparation which is prepared by adopting a chicken pox human immune globulin as a main active ingredient and adding with accessories acceptable in pharmacy, wherein, the chicken pox human immune globulin is prepared by adopting blood plasma obtained after a varicella vaccine is used for immunizing human bodies as raw material. The drug for treating chicken pox can be used for treating or preventing cytomegalovirus diseases and has wide application prospect.

The present invention relates to novel Varicella-zoster virus strain and to a chicken pox and herpes zoster virus vaccine using the same. More particularly, the present invention relates to genome DNA of VZV MAV/06 strain isolated from a Korean patient, to an open reading frame (ORF) thereof, to a protein coded by the genome DNA of VZV MAV/06 strain and the ORF thereof, and to a vaccine composition which contains the protein as an active ingredient.

There is provided a pharmaceutical drug, particularly a novel compound useful for prophylaxis or a therapeutic treatment of various diseases involving infections with viruses of the herpesvirus family, specifically various herpesvirus infections such as varicella (chicken pox) via varicella zoster virus, varicella zoster via recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis via HSV-1 and genital herpes via HSV-2 infection. An N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carboxamide derivative, of which phenyl group is substituted at position 4 with a specific 5- or 6-membered heteroaryl group, and a salt thereof have an effective anti-virus activity, and the oral administration thereof at a low dose enabled the therapeutic treatment of the above diseases.

The invention discloses a preparation method of a chicken pox virus antibody, belonging to the technical field of biology. The method comprises the following steps: (1) culturing the chicken pox virus, and preparing a coarse antigen; (2) preparing the concentrated and purified antigen; (3) preparing the animal immune and antiserum; and (4) purifying the antibody. The antibody prepared by the method disclosed by the invention has the advantages of high purity and favorable specificity, and can be widely used for preparing reagents for detecting chicken pox virus infection.

Disclosed is a recombined chicken pox virus vaccine rFPV-12LSH5H9, its construction method and use, wherein the construction process consists of placing AIV HA gene fragment containing H5 hypotype and H9 hypotype onto the downstream of right promotors, inserting into chicken poxviridae expression vector p12-18 containing FPV duplicated non-indispensable fragment FPV1-2 and reported genes through backside cascade connection to construct transition vector p12LSH5H9, then transforming chick embryo desmocyte infected with wt-FPV with the transition vector p12LSH5H9, and obtaining co-expression H5 and H9 hypotype AIV HA gene rFPV-12LSH5H9 through consanguinity recombination.

The present invention belongs to the field of biotechnology, and is especially one kind of recombinant live carrier vaccine co-expressing pig gyrate virus and foot and mouth disease virus. The present invention aims at providing two recombinant chicken pox viruses to co-express capsid protein ORF2 or its fusion protein ORF2-ORF1 of the China epidemic strain of type-II pig gyrate virus and the structural protein precursor P1 of the China epidemic strain NY00 of type-O foot and mouth disease virus, and for serving as the duplex live carrier gene engineering vaccine to prevent PCV2 and FMDV infection. The two recombinant chicken pox viruses can stimulate mouse to generate effective body fluid immunity and cell immunity, and are safe to experimental animals without any pathological phenomenon.

The present invention relates to a heat-resisting freeze-dried protection agent for chicken pox freeze-dried vaccine and its preparation process. It is characterized by that its composition includes gelatin 3%, lactose 5-6%, EDTA 2%, PVP (K90) 5%, sorbitol 2%, sodium glutamate 1%, beef peptone 2%, bovine serum albumin 1% and Vc 0.1%, and the rest is distilled water. Said invention also provides its preparation method and concrete steps, and its application.

Disclosed is a recombined chicken pox virus vaccine rPFV-12LSH9A, preparation process and use, wherein the construction process consists of placing AIV HA gene fragment containing H9 hypotype onto the downstream of right promotors, inserting into chicken poxviridae expression vector p12-18 containing FPV duplicated non-indispensable fragment FPV1-2 and reported genes to construct transition vector, then transforming chick embryo desmocyte infected with wt-FPV with the transition vector, and obtaining rFPV expressing H9 hypotype AIV HA gene through consanguinity recombination, i.e. recombinant chicken poxviridae vaccine rFPV-12LSH9A.

The medicine for preventing and treating chicken pox is prepared with 13 kinds of Chinese medicinal materials including gromwell, buffalo horn, cimicifuga rhizome, cicada slough, isatis leaf, etc. in certain proportion, and through pulverizing, milling into fine powder and mixing. Before clinical using, the medicine is soaked in boiled water for 30-60 min for the effective components in the medicine to be leached out fully and for the sick chicken to absorb well, and small amount of sugar and vitamin C are added to raise the treating effect. The medicine has high clinical curative rate, no negative effect, no residue and no resistance.

The invention discloses a Chinese herbal medicine for treating chicken pox. The Chinese herbal medicine is prepared from the following medicines in parts by weight: 5-15 parts of fineleaf schizonepeta herb, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of Szechuan lovage rhizome, 6-12 parts of sinkiang arnebia root peel, 4-12 parts of cicada shell, 5-10 parts of coptis root, 5-10 parts of baikal skullcap root, 5-10 parts of amur corktree bark, 6-15 parts of skunk bugbane, 5-15 parts of common lophatherum herb and 5-15 parts of honeysuckle stem. The Chinese herbal medicine is prepared by carrying out the following steps: adding 1200 parts of water; boiling, and decocting with soft fire for 20-30 minutes; collecting supernatant by filtering; decocting for three times, and mixing supernatant decocted in the three times; bottling, and sterilizing at high temperature for later use. The fineleaf schizonepeta herb is taken as a monarch; the divaricate saposhnikovia root and the Szechuan lovage rhizome are taken as ministers; the sinkiang arnebia root peel, the cicada shell, the coptis root and the baikal skullcap root are taken as assistants; the amur corktree bark, the skunk bugbane, the common lophatherum herb and the honeysuckle stem are taken as guides. The Chinese herbal medicine composition for treating chicken pox has a good effect, is safe and free from side effects, convenient to take and low in production cost, and is an ideal medicament for treating chicken pox by clearing away heat and toxic materials.

The invention provides a medicine for treating chicken pox in children. The medicine is characterized by being prepared from the following components in parts by weight: 10-20 parts of radix isatidis, 10-15 parts of fructus forsythiae, 10-15 parts of semen plantaginis, 10-12 parts of scutellaria baicalensis, 10-15 parts of moutan bark, 10-12 parts of Chinese violet, 5-6 parts of gypsum, 10-12 parts of radix scrophulariae, 10-12 parts of rhizoma alismatis, 10-12 parts of peppermint, 10-12 parts of schizonepeta, 10-12 parts of rhizoma anemarrhenae, 10-12 parts of burdock, 10-12 parts of rhizoma cimicifugae, 10-12 parts of kudzu vine root, 10-12 parts of cornu bubali, 10-12 parts of moutan bark and 5-8 parts of licorice root. The medicine has the advantages of use of easily available raw materials, low cost, remarkable treatment effect and the like.

The invention belongs to the technical field of traditional Chinese medicine cores and particularly relates to a scent bag medicine core capable of preventing infectious diseases. The scent bag medicine core capable of preventing infectious diseases mainly solves the technical problem that an existing infectious disease treatment method brings large mental and economic burdens to patients. According to the technical scheme, the scent bag medicine core capable of preventing infectious diseases is prepared from, by weight, 10-15 parts of honeysuckle, 6-12 parts of wrinkled giant hyssop, 6-12 parts of eupatorium, 5-10 parts of cloves, 6-12 parts of cyrtomium fortunei, 6-10 parts of folium artemisiae argyi, 6-10 parts of amomum tsaoko, 5-10 parts of amomum cardamomum, 5-10 parts of fructus amomi, 10-15 parts of acorus gramineus, 10-15 parts of polygala tenuifolia, 5 parts of cinnamon, 3 parts of borneol and 6-10 parts of evodia rutaecarpa. The scent bag medicine core has a very good curative effect on preventing and treating respiratory system infectious diseases, flu, hand, foot and mouth diseases, mumps, chicken pox, bird flux and the like and will not bring large mental and economic burdens to patients.