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Novel ointment for treating microorganism infection skin disease and preparation process thereof

A technology of ointment and vitamins, which is applied in the direction of medical formula, ointment delivery, drug combination, etc., can solve the problems of low cure rate, difficult effect, easy recurrence, etc., and achieve the effect of repairing the skin

Inactive Publication Date: 2012-04-25
苏州泰利三佳纳米科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing medicaments have a high effect on the disease, but the cure rate is low and relapse is easy. This is mainly because the existing medicaments mainly use antibiotics to kill bacteria and hormones to stimulate the body to antibacterial.
Clinically, these drugs show rapid effects, but the follow-up is weak, and it is difficult to show long-lasting effects. At the same time, the use of antibiotics will gradually lead to drug resistance of skin diseases.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Trivalent silver ion compound 0.1g, keratinase 0.2g, water-soluble keratin 0.5g, multivitamin 2 tablets, white petrolatum 94.3g. Take the trivalent silver ion compound, vitamin tablets, keratinase, keratin and other ingredients according to the above proportions, grind them into powder, add white vaseline and mix evenly to get the finished ointment.

Embodiment 2

[0019] 0.2g of trivalent silver ion compound, 0.3g of keratinase, 2.5g of water-soluble keratin, 3 tablets of multivitamins, and 96.5g of white petrolatum. Take the trivalent silver ion compound, vitamin tablets, keratinase, keratin and other ingredients according to the above proportions, grind them into powder, add white vaseline and mix evenly to get the finished ointment.

Embodiment 3

[0021] Trivalent silver ion compound 0.3g, keratinase 0.4g, water-soluble keratin 5g, multivitamin 3 tablets, white petrolatum 98.7g. Take the trivalent silver ion compound, vitamin tablets, keratinase, keratin and other ingredients according to the above proportions, grind them into powder, add white vaseline and mix evenly to get the finished ointment.

[0022] The above-mentioned trivalent silver ion compound can be prepared by the following method: 0.1-0.3 part of sodium hydroxide (potassium), 1-2 part of tetrasilver tetroxide, 1-3 part of sodium persulfate (potassium), fully grind and mix uniformly, The fineness of the particles is 100-200 mesh, add 3-5 parts of deionized water (w / v) to every 10 parts of the above mixture, adjust it into a semi-fluid state, keep it at 50-80°C for 1-2 hours, filter it, and rinse it with distilled water At least three times to wash away the unreacted sodium (potassium) persulfate, sodium (potassium) hydroxide and the reaction product sodium...

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Abstract

The invention relates to a ointment and a preparation process thereof. The novel ointment for treating the microorganism infection skin disease consists of the following materials in part by mass: 0.1 to 0.3 part of trivalent silver ion compound, 0.2 to 0.4 part of keratinase, 0.5 to 5 parts of water-soluble keratin, 2 to 3 parts of composite vitamin and 94.3 to 98.7 parts of white petroleum jelly. The preparation process particularly comprises the following steps of: grinding 0.1 to 0.3 part of trivalent silver ion compound, 0.2 to 0.4 part of keratinase, 0.5 to 5 parts of water-soluble keratin and 2 to 3 parts of composite vitamin into powder; and adding 94.3 to 98.7 parts of white petroleum jelly into the powder and uniformly mixing the mixture. The ointment has the effects of rapidly sterilizing and relieving itching, expelling toxin and removing rot, and repairing skin. The ointment is suitable for treating and protecting a local skin disease caused by microorganism infection, such as fugal infection of hand and foot, tinea corporis, tinea cruris and onychomycosis (ringworm of the nails) caused by fungi, erysipelas and leprosy caused by bacteria, chicken pox, flat wart and herpes caused by virus and the like.

Description

Technical field: [0001] The invention relates to a novel ointment for treating skin diseases infected by microorganisms and a preparation method thereof. Background technique: [0002] In medicine, dermatosis is a disease related to the skin, and it is one of common diseases and frequently-occurring diseases that seriously affect people's health, such as leprosy, scabies, fungal diseases, skin bacterial infections, etc. Dermatosis is the skin (including hair and nails) affected by internal and external factors (microbial infection), its shape, structure and function all change, resulting in pathological processes, and correspondingly produce various clinical manifestations. The incidence rate of skin diseases is very high, most of which are relatively mild, and often do not affect health, but a few of them are severe and even life-threatening. [0003] In the medicament that present market treatment microbial infection causes dermatosis, based on ointment. Existing medicam...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/48A61K9/06A61P17/00A61P31/00A61K38/17A61K33/38A61K31/05A61K31/07A61K31/51A61K31/525A61K31/4415A61K31/714A61K31/375A61K31/59A61K31/355
Inventor 郭锋利许晓东周国富
Owner 苏州泰利三佳纳米科技有限公司
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