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10 results about "Dna encoding" patented technology

An attack tracing method and system for end-to-end data transmission of optical communication

This invention discloses an attack tracing method and system for end-to-end data transmission in optical communication, belonging to the field of optical fiber communication technology. The method includes: processing an initial key value using a hash function and DNA encoding to generate a DNA sequence; concatenating the DNA sequence to generate a session key and calculating its hash value; calculating a single-byte XOR checksum of the original data to generate extended data, generating ciphertext based on the extended data, and calculating a digest of the ciphertext; decrypting the ciphertext and performing XOR checksum consistency verification to obtain an event digest; calculating a root hash based on the key digest, parameter digest, ciphertext digest, and event digest, storing the root hash in the block header, and performing attack tracing on the block header to obtain the attack tracing result. This invention introduces four-dimensional chaos and DNA encoding to generate a high-entropy key, dynamically storing and updating the key through blockchain, while simultaneously achieving single-root verifiable attack tracing and quickly locating problematic nodes.
Owner:NANJING UNIV OF INFORMATION SCI & TECH

Modified mrna for multicellular transformation

PendingCN122376717ACancer cellMessenger RNA
Synthetic bacterial messenger RNA can be used to make autologous, allogeneic or direct nucleic acid cancer vaccines. Cancer cells are transfected in vitro or in vivo with mRNA obtained from DNA encoding immunogenic bacterial proteins. The immune response to cancer is generated by direct administration of the mRNA in vivo or administration of a vaccine made from cancer cells in vitro. Codon modification of the mRNA can optimize expression of the immunogenic polypeptide in cancer cells.
Owner:TUHELA BIOSCIENCES

Protein having n-sulfotransferase activity and DNA encoding said protein

PCT designated stageWO2026116455A1FungiBacteriaSulfotransferase activityDna encoding
The purpose of the present invention is to provide a means for producing a non-animal-derived modified heparosan compound with higher efficiency than conventional means. Provided is any one of the following proteins [1] to [3] fused to a TRX tag. [1] A protein which comprises the amino acid sequence represented by SEQ ID NO: 1. [2] A protein which comprises an amino acid sequence having a structure wherein 1 to 20 amino acid residues are deleted, substituted, inserted, or added in the amino acid sequence represented by SEQ ID NO: 1 and which has N-sulfotransferase activity. [3] A protein which comprises an amino acid sequence having 70% or more identity to the amino acid sequence represented by SEQ ID NO: 1 and has N-sulfotransferase activity.
Owner:KIRIN BIOMATERIALS CO LTD

Antibodies that bind human and mouse INSL5 and encoding nucleic acids thereof

ActiveUS12637508B2Nucleic acid vectorImmunoglobulins against hormonesAssayDna encoding
The present invention provides compounds and methods targeting insulin-like peptide-5 (INSL5), including antibodies, cells and vectors comprising DNA encoding the same, and methods for producing the antibodies. In addition, the present invention provides for use of INSL5 antibodies in diagnostic assays.
Owner:ELI LILLY & CO

DUX4 RNA silencing using RNA-targeting CRISPR-Cas13b

ActiveKR102991281B1DiseaseDirect repeat
An RNA interference-based product and method for inhibiting the expression of the double homeobox 4 (DUX4) gene on human chromosome 4q35 are disclosed. The invention comprises the silencing of the Cas13 protein of RNA, wherein Cas13 is specifically targeted to a DUX4 region of interest using a sequence-specific guide RNA (gRNA). The recombinant adeno-associated virus of the invention is constructed with a Cas13 direct repeat sequence and delivers DNA encoding an inhibitory gRNA that knocks down DUX4 expression. The method is applicable to the treatment of muscular dystrophy, including but not limited to facial-scapulohumeral muscle dystrophy (FSHD), and other disorders, including cancer, associated with elevated DUX4 expression.
Owner:RES INTITUTE AT NATIONWIDE CHILDRENS HOSPITAL

Method for producing microorganisms having N-deacetylation activity and N-sulfation activity, method for producing heparosan-derived compounds, and microorganisms having N-deacetylation activity and N-sulfation activity

The present invention relates to a method for producing a microorganism having N-deacetylation activity and N-sulfation activity, comprising the steps of (I) modifying the nucleotide sequence of DNA encoding N-deacetylase / N-sulfotransferase and (II) introducing the DNA containing the modified nucleotide sequence in step (I) into a microorganism so that it can express, wherein step (I) is a step of codon optimization to match the codon usage frequency of a different species of organism than the microorganism. The present invention also relates to a method for producing a microorganism having N-deacetylation activity and N-sulfation activity, comprising the step of (i) expressing a specific protein in the microorganism.
Owner:RENESSELAER POLYTECHNIC INST +2

Color image encryption method based on memristor and DNA encoding

This application provides a color image encryption method based on memristors and DNA encoding, relating to the fields of image encryption and information security technology, and solving the technical problems of insufficient key randomness and inadequate anti-attack capability. The method includes: obtaining a truly random bit sequence generated by a memristor; iterating the initial parameters and control parameters through a chaotic system to generate a first chaotic sequence and a second chaotic sequence; performing a first encryption transformation on the original pixel data based on the first chaotic sequence to obtain an intermediate encrypted data sequence; performing a second encryption transformation on the second chaotic sequence to obtain a numerical key, and dynamically selecting a DNA encoding rule according to the second chaotic sequence; and performing DNA encoding operations on the intermediate encrypted data sequence based on the numerical key and the selected DNA encoding rule to obtain ciphertext image data. This application is used in image encryption processes.
Owner:WUXI PROFESSIONAL COLLEGE OF SCI & TECH

A signature image DNA coding storage and anti-fake verification method and system based on feature learning, a computer device and a readable storage medium

This invention discloses a method, system, computer equipment, and readable storage medium for signature image DNA encoding storage and anti-counterfeiting verification based on feature learning, belonging to the field of electronic information technology. The method includes: extracting high-dimensional discriminative feature vectors from the signature image to be verified using a feature extractor; inputting the vectors into a trained sequence encoder to generate a DNA sequence; synthesizing a reverse complementary sequence to prepare a labeled probe; hybridizing the probe with the registered DNA sequence of the target signer; measuring the hybridization yield; if the yield exceeds a preset threshold, the signature is determined to be genuine; otherwise, it is a forged signature. This invention is the first to integrate handwritten signature anti-counterfeiting with DNA storage. Through three core components—a feature extractor, a sequence encoder, and a hybridization predictor—and multi-task joint training, genuine signature pairs are encoded as high-hybridization-yield sequences, while genuine and forged signature pairs are encoded as low-hybridization-yield sequences, achieving physical-level anti-counterfeiting verification based on molecular hybridization. The verification process of this invention is inherently parallel, energy-efficient, and highly accurate, meeting the needs of practical anti-counterfeiting applications.
Owner:XI AN JIAOTONG UNIV