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31 results about "Herpes Labialis" patented technology

Herpes simplex, caused by type 1 virus, primarily spread by oral secretions and usually occurring as a concomitant of fever. It may also develop in the absence of fever or prior illness. It commonly involves the facial region, especially the lips and the nares. (Dorland, 27th ed.)

Herpes simplex virus I-type gene recombinant attenuated live vaccine and preparation method thereof

The invention discloses a herpes simplex virus I-type gene recombinant attenuated live vaccine and a preparation method thereof. The attenuated live vaccine is characterized in that: US2, US3, US4 and US5 genes in a genome and other duplicated or infected nonessential gene fragments are jointly knocked out, wherein other duplicated or infected nonessential gene fragments are US9-US12 genes. The method comprises the following steps: separating and identifying wild HSV-1 (herpes simplex virus-1) from blister fluid of a patient with remarkable herpes labialis and herpes progenitalis; propagating and extracting a complete genome of virus; co-transfecting a Vero cell with a shuttle vector containing homologous flanking sequences of 700bp to 2000bp on the left and right sides of a fluorescent expression gene and the HSV gene to be knocked off; and selecting the recombinant virus by using one or combination of multiple fluorescent protein genes serving as a marker under fluorescent microscope, and acquiring the required recombinant attenuated live vaccine after plaque purification.
Owner:郑州金森生物科技工程有限公司

Anti-herpes simplex virus polypeptide and its application

The invention relates to the technical field of biology, and discloses anti-herpes simplex virus polypeptide and its application. Tests show that the anti-herpes simplex virus polypeptide has a high efficiency inhibition effect to the herpes simplex virus propagation, and the anti-herpes simplex virus polypeptide is used for producing the medicines for treating and preventing diseases related to herpes simplex. The invention provides a medicinal preparation which takes the anti-herpes simplex virus polypeptide as the effective component for treating the herpes caused by the herpes simplex virus, and has a obvious effectiveness for treating herpes, the effective rate for treating herpes simplex, labial herpes and genital herpes can reach to 100%. And the anti-herpes simplex virus polypeptide has low recurrence rate after heal and no toxic side effect.
Owner:WUHAN MORE BIOTECH

Compound preparation used for preventing and treating oral cavity diseases of pets

The invention provides a compound preparation used for preventing and treating oral cavity diseases of pets. The compound preparation comprises: lysozyme, glycine, aspartic acid, Vitamin B1 nitrate, Vitamin B2, menthol and montmorillonite according to the weight ratio of: 0.03-0.15 parts of the lysozyme, 0.30-1.5 parts of the glycine, 0.12-0.28 parts of the aspartic acid, 0.012-0.028 parts of theVitamin B1 nitrate, 0.03-0.07 parts of the Vitamin B2, 0.12 parts of the menthol, and the montmorillonite is added to 12 parts. The compound preparation can be extensively applied to treatment on diseases of injury, inflammation or ulcer on mouth mucosa, gingiva and lips, herpes labialis, false teeth base plate pressure sores and the like of cats and dogs in all ages. The compound preparation canbe adhered to an affected part for relieving pain and promoting healing of the affected part, and also can be used as a dressing after exodontias and odontolith scaling, and also can used for treatingangular cheilitis, thick and white tongue coating and bad breath.
Owner:山东亚华生物科技有限公司

Therapeutic composition to treat lesions caused by herpes simplex virus

The present invention is generally directed toward therapeutic compositions for treating infections caused by Herpes Simplex Virus (“HSV”). The therapeutic compositions meet a long felt need in the art of providing a treatment for lesions that result from HSV that drastically reduce the duration of a cold sore when vesicles have already appeared and a treatment that will prevent the outbreak of a lesion and formation of vesicles when applied in the prodormal stage. The therapeutic compound comprises a mixture of Acyclovir (“ACV”), Penciclovir (“PCV”), and 2-Deoxy-D-Glucose (“2-DDG”). The therapeutic compositions of the present invention include multiple formulations of the three active ingredients and may also include inactive ingredients.
Owner:G2L TOUCH

Amide derivative

There is provided a pharmaceutical drug, particularly a novel compound useful for prophylaxis or a therapeutic treatment of various diseases involving infections with viruses of the herpesvirus family, specifically various herpesvirus infections such as varicella (chicken pox) via varicella zoster virus, varicella zoster via recurrent infection with latent varicella zoster virus, herpes labialis and herpes encephalitis via HSV-1 and genital herpes via HSV-2 infection. An N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carboxamide derivative, of which phenyl group is substituted at position 4 with a specific 5- or 6-membered heteroaryl group, and a salt thereof have an effective anti-virus activity, and the oral administration thereof at a low dose enabled the therapeutic treatment of the above diseases.
Owner:ASTELLAS PHARMA INC

Use of chloride 13-hexyl berberine and chloride 13-hexyl palmatine in preparation of medicine for treating skin mucosa herpes viral infection

The invention relates to a method for using alcaine 13-hexyl berberine and relative alcaine 13-hexyl palmatine to prepare the drug that treats herpesvirus infection on skin mucosa. And said two compounds have strong functions to resist HSV, I, II herpesvirus. And their restrain density (IC50) of external resist HSV-1 type and HSV-2 type is 0.78-1.56 mug / ml. And the 0.5% 13-hexyl berberine or alcaine 13-hexyl palmatine, or 1% emulsion can treat bleb, stronger than 3% assili lovou.
Owner:CHUGOKU IGAKU KAGAKUIN HIFUBIYOU KENKYUSHO

Therapeutic composition to treat lesions caused by herpes simplex virus

The present invention is generally directed toward therapeutic compositions for treating infections caused by Herpes Simplex Virus (“HSV”). The therapeutic compositions meet a long felt need in the art of providing a treatment for lesions that result from HSV that drastically reduce the duration of a cold sore when vesicles have already appeared and a treatment that will prevent the outbreak of a lesion and formation of vesicles when applied in the prodromal stage. The therapeutic compound comprises a mixture of Acyclovir (“ACV”), Penciclovir (“PCV”), and dimethyl sulfoxide (“DMSO”). The therapeutic compositions of the present invention include multiple formulations of the three active ingredients and may also include inactive ingredients and / or additional active ingredients.
Owner:G2L TOUCH

Film-forming composition, and use thereof for treating herpes

The present invention relates to a topical film-forming composition including, in a pharmaceutically acceptable medium: 5 to 30 wt % of ethyl cellulose; 0.1 to 10 wt % of an auxiliary film-forming agent; 0.1 to 20 wt % of one or more triacids, at least one of which is boric acid; and 60 to 95 wt % of an organic solvent, the percentages being expressed by weight relative to the total weight of the composition. The invention also relates to the use of such a composition in a method for treating herpes, in particular herpes labialis.
Owner:URGO RECH INNOVATION & DEVEMENT

Composition for treating herpes simplex viral infections, the method, use and process by which the composition is utilized and the manufacture of the composition

InactiveUS20100189668A1Assist absorptionCosmetic preparationsBiocideHerpes simplex virusEssence oil
This invention relates to a composition, method and process for the treatment of the herpes simplex virus which causes cold sores in humans by a topical application of a blend of essential oils and other natural based materials as a dilutant, all of which may be delivered in either a solid, paste, powder, gel or liquid form to the affected area.
Owner:MCCULLOUGH GREGORY K +2

Therapeutic composition to treat lesions caused by herpes simplex virus

The present invention is generally directed toward therapeutic compositions for treating infections caused by Herpes Simplex Virus (“HSV”). The therapeutic compositions meet a long felt need in the art of providing a treatment for lesions that result from HSV that drastically reduce the duration of a cold sore when vesicles have already appeared and a treatment that will prevent the outbreak of a lesion and formation of vesicles when applied in the prodromal stage. The therapeutic compound comprises a mixture of Acyclovir (“ACV”), Penciclovir (“PCV”), and dimethyl sulfoxide (“DMSO”). The therapeutic compositions of the present invention include multiple formulations of the three active ingredients and may also include inactive ingredients and / or additional active ingredients.
Owner:G2L TOUCH

Traditional Chinese medicine for treating herpes labialis

The invention discloses a traditional Chinese medicine for treating herpes labialis. The traditional Chinese medicine is prepared from traditional Chinese herbal medicines, namely phoenix tree leaves, berchemia racemosa, berchemia floribunda, ipomoea pes-caprae, white willow barks, daphne acutiloba, clintonia udensis, macropanax rosthornii, delphinium bonvalotii, campylotropis velutina, kalopanax septemlobus barks, damnacanthus indicus, carduus crispus, kopsia officinalis, omei angiopteris, roots of clematis argentilucida, broussonetia kazinoki, roots of desmodium caudatum and anser albifrons. The traditional Chinese medicine is prepared from pure natural traditional Chinese herbal medicines as raw materials, is capable of treating both symptoms and root causes, and is definite in treatment effect and free of toxic or side effect, and diseases are not liable to reoccur.
Owner:闫大伟

Anti-Viral Composition for the Topical Treatment of Herpes Labialis (Cold Sores) and Method for Use Thereof

A composition for the treatment of Herpes Labialis which contains CTC-96 as the active ingredient is disclosed. Methods for using the composition are also disclosed. The composition may be used as a topical ointment.
Owner:REDOX PHARMA

Traditional Chinese medicine preparation for treating infantile hand-foot-mouth disease and preparation method

The invention discloses a traditional Chinese medicine preparation for treating infantile hand-foot-mouth disease and a preparation method, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine preparation is prepared from the following raw materials as effective ingredients: isatis root, smallfruit fig aerial root, carrot, viburnum dilatatum, ligustrum sinense, cortex dictamni, tamarisk, centella, stinkweed, chushan lip-fern herb, rhizoma cimicifugae, nutgall, mint, myricaria germanica, licorice and acacia catechu. The medicinal materials selected by the traditional Chinese medicine preparation are appropriate in compatibility and are combined to achieve the effects on clearing away heat and toxic materials, dispelling wind and arresting itching, strengthening superficial body resistance and promoting eruption, eliminating dampness and astringing sores, invigorating qi and strengthening the middle-jiao, relieving spasm and pain and the like; the traditional Chinese medicine preparation has the advantages of exact curative effect, high effect taking speed, high cure rate, no toxic or side effect, safety and reliability when used for treating symptoms, such as cough, herpes, herpes labialis, rhinorrhea, salivation, stomatalgia, corrosive blister, blister or bleb injury, meloschisis and tongue and gum painful miliary blister, caused by infantile hand-foot-mouth disease; and therefore, the traditional Chinese medicine preparation can be widely used for clinically treating infantile hand-foot-mouth disease.
Owner:王晓丽

Traditional Chinese medicine composition for treating herpes labialis and preparation method thereof

The invention discloses a traditional Chinese medicine composition for treating herpes labialis and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by weight, 11-19 parts of radix scutellariae, 15-25 parts of fructus forsythiae, 10-20 parts of fructus gardeniae, 14-22 parts of radix asparagi, 8-16 parts of rheum officinale, 6-13 parts of lemon grass, 10-20 parts of poria cocos, 7-14 parts of rhizoma alismatis, 15-25 parts of honeysuckle flowers, 16-24 parts of licorice roots, 9-18 parts of radix rehmanniae, 7-14 parts of rhizoma coptidis, 12-23 parts of medulla junci, 10-20 parts of medulla tetrapanacis, 8-16 parts of cortex phellodendron Chinese, 15-25 parts of bitter gourd seeds, 18-26 parts of sophora flowers, 9-18 parts of radix scrophulariae and 10-20 parts of rhizoma anemarrhenae. The traditional Chinese medicine composition is prepared from radix scutellariae, fructus forsythiae, fructus gardeniae, radix asparagi, rheum officinale, lemon grass, medulla junci, medulla tetrapanacis, cortex phellodendron Chinese, bitter gourd seeds and sophora flowers through scientific compatibility, can achieve the effects of clearing away heat and toxic materials, dispelling wind and purging fire, clearing away the heart-fire and heat, nourishing yin for lowering fire and guiding fire to origin through the synergistic effect of the raw materials, can be effectively used for treating the herpes labialis and is exact in treatment effect, good in treatment effect, capable of rapidly achieving the effects and short in treatment cycle, and the effective rate reaches 95% or above.
Owner:SUZHOU BINUOJIA PHARMA CO LTD

Use of medicine for treating genital organ infection as for treating flu and simple herpes

The present invention relates to an application of Chinese medicine preparation for curing trichomonad and pathogen infection in the preparation of medicine for curing influenza virus and herpes simplex virus infection. Said invention uses forsythia fruit volatile oil and borneol as prescription medicine, and adds the auxiliary solvent to make them into liniment or injection or suppository. Said medicine series can be used for curing influenza, genital herpes, herpes labialis and tinea manuum and tinea pedis, etc.
Owner:李强 +1

Unguent used for treating herpes labialis and preparation method thereof

The invention relates to an unguent used for treating herpes labialis. The unguent is prepared from the following medicines in parts by weight: 35-50 parts of gentian violet, 35-50 parts of fructus forsythiae, 30-50 parts of coptis chinensis, 30-50 parts of realgar, 30-50 parts of ground beeltle, 25-40 parts of blumea balsamifera, 25-40 parts of tribulus terrestris, 25-40 parts of acalypha, 25-40 parts of eriocaulon buergerianum, 10-25 parts of rhizoma alismatis, 10-25 parts of polygonum cuspidatum, 23-29 parts of matrine, 23-29 parts of peppermint oil, 23-29 parts of corydalis tuber, 30-45 parts of polyethylene glycol, 30-35 parts of ethyl alcohol, 25-35 parts of boric acid, 32-40 parts of polyvinyl alcohol, 30-40 parts of propyl acetate, 10-20 parts of polyurethane, 5-15 parts of gum rosin, 1-15 parts of acetone and 1-15 parts of borneol. The invention also discloses a preparation method thereof. The unguent provided by the invention can be used for treating herpes labialis, is simple and convenient to use and has the advantages of quick effectiveness in treating herpes labialis, short course of treatment and high cure rate.
Owner:GUANGXI UNIV

Preparation and application of a new type of interferon alpha-2b wet wipes

The invention belongs to the technical field of wet tissues and application thereof and specifically relates to preparation and application of a novel interferon alpha-2b wet tissue. The novel interferon alpha-2b wet tissue provided by the invention comprises medicine liquid and a carrier carrying the medicine liquid, wherein the medicine liquid contains interferon alpha-2b, a protein stabilizer and water, and the mass ratio of the protein stabilizer to interferon alpha-2b is 1: (4-20), preferably 1: (4-10) and more preferably 1: 4. The invention solves the problem of bioactivity of interferon alpha-2b in the interferon alpha-2b wet tissue and creates a wet tissue containing interferon alpha-2b; and furthermore, the wet tissue containing interferon alpha-2b can be applied to auxiliary treatment of viral infection type skin diseases, such as herpes labialis, herpes zoster, genital herpes, genital warts and the like, and can well solve various disadvantages of various conventional methods for treating viral infection type diseases.
Owner:SHANGHAI HUAXIN HIGH BIOTECH

Preparation method and application of anti-herpes simplex virus composite IgY antibody

The invention discloses a preparation method and application of an anti-herpes simplex virus complex IgY antibody, and belongs to the technical field of herpes simplex virus resisting. The preparationmethod includes the following steps that step 1, an immunogen is prepared, specifically, a herpes simplex virus type 1 and a herpes simplex virus type 2 are taken and mixed and then the mixture is mixed with a Freund's complete adjuvant and a Freund's incomplete adjuvant separately and stirred and emulsified to prepare a water-in-oil Freund's complete adjuvant and Freund's incomplete adjuvant herpes simplex virus immunogen; and step 2, immunity is performed, specifically, the Freund's complete adjuvant immunogen is injected into laying hens. Application to ocular conjunctiva, a nasal cavity and an oral cavity is achieved, no limitations and side effects of systemic medication exist, the local application taking effect is quick, the dosage is low, the curative effect is good, the normal micro-ecological environment on the surface of the conjunctiva, the nasal cavity and the oral cavity is not absorbed and damaged, no toxic and side effects exist, and diseases of herpes labialis, dermatitis herpetiformis and herpes zoster caused by the herpes simplex virus type 1 and the herpes simplex virus type 2 and viruses with a common antigen with the herpes simplex virus type 1 and the herpessimplex virus type 2 are prevented and treated.
Owner:南京道大药业有限公司

Lipstick for auxiliary treatment of herpes labialis and preparation method thereof

The invention discloses a lipstick assisting in treatment of herpes labialis and a preparing method thereof. The lipstick assisting in treatment of herpes labialis is mainly prepared from honeysuckle flower, radix puerariae, licorice root, menthol, beewax, vaseline, arnebia root oil and wool fat. The lipstick can be used for assisting in treatment of herpes labialis, lip dryness and crack as well as oral infection. The lipstick has a good moistening effect and anti-crack effect.
Owner:贵州威利德制药有限公司

A traditional Chinese medicine spray for treating skin disease or mucous cavity disease

The invention discloses a traditional Chinese medicine pressurized spray for treating skin disorders or mucosa orifice diseases. The pressurized spray is prepared from the following raw material medicines in parts by weight: 250 to 500 parts of herba euphorbiae humifusae, 50 to 250 parts of cortex dictamni, 50 to 250 parts of clove, 25 to 175 parts of tokyo violet herb, 25 to 175 parts of rhizoma dryopteris crassirhizomae, 25 to 175 parts of purslane and 5 to 50 parts of borneol. The invention also provides a detection method thereof. The method comprises the following steps: using a thin-layer chromatography to qualitatively identify the herba euphorbiae humifusae, the clove, the tokyo violet herb and the cortex dictamni, and using an HPLC (high performance liquid chromatography) to determine the content of the herba euphorbiae humifusae. The pressurized spray provided by the invention has unique curative effects on early stage pain and after pain of herpes. The preparation has the efficacies of clearing heat and removing toxicity, dispelling wind and arresting itching and activating meridians to stop pain. The preparation has stronger actions of antivirus and broad-spectrum antibacterial. The pressurized spray can be used for treating various skin and mucosaorifice diseases, such as herpes zoster, herpes labialis, varicella, beriberi, vaginitis and the like.
Owner:JINAN MILITARY REGION LOGISTICS DEPT MEDICINE & INSTR TEST INST PLA

Amide derivative

The present invention provides a medicament, in particular, a novel compound for preventing or treating various infections caused by herpesviridae viruses, especially infections caused by various herpes viruses, such as those caused by varicella zoster virus. Varicella (chickenpox), varicella zoster caused by multiple infections of latent varicella-zoster virus, cold sores and herpes encephalitis caused by HSV-1 infection, and genital herpes caused by HSV-2 infection. The present invention provides N-{2-[(4-substituted phenyl)amino]-2-oxoethyl}tetrahydro-2H-thiopyran-4-carbamoyl derivatives and salts thereof, wherein, phenyl The 4-position is substituted by a specific 5- or 6-membered heteroaryl group, it has effective antiviral activity, and it can be administered orally at a low dose to treat the above-mentioned diseases.
Owner:ASTELLAS PHARMA INC

Agent for prevention/treatment of disease caused by acyclovir-resistant herpesvirus

InactiveUS20090048310A1Excellent anti-viral activityImprove pharmacokineticsBiocideOrganic chemistryRecurrent infectionsVaricella-zoster virus infection
[Problems] To provide an agent useful for the prevention or treatment of various diseases associated with the infection with acyclovir-resistant viruses of the family Herpesviridae, specifically various infectious caused by herpes viruses, such as varicella associated with varicella-zoster virus infection, herpes zoster associated with recurrent infection with latent varicella-zoster virus, and herpes labialis, herpes encephalitis and genital herpes associated with HSV-1 and HSV-2 infection, and the like.[Means for Solving Problems] An N-[2-[(4-substituted phenyl)amino]-2-oxoethyl]tetrahydro-2H-thiopyran-4-carboxamide derivative in which the phenyl group is substituted at position 4 by a specific 5- or 6-membered heteroaryl group. This derivative has an excellent anti-viral activity against acyclovir-resistant herpes viruses and, therefore, is effective for the treatment of the diseases as mentioned above.
Owner:ASTELLAS PHARMA INC

Treatment of herpes simplex symptoms on skin and mucous membrane of mammals

Antiviral compositions, method of manufacturing such compositions and uses of the composition. The present composition is intended for use as an antiviral medicament for topical application on areas of the mammal skin or mucous membranes affected by a herpes virus, in particular herpes simplex virus. The composition comprises silver ions complexed with polyamine polymers, optionally in combination with other antiviral agent. By the present invention, herpes cold sores can be successfully treated or outbreaks thereof even prevented.
Owner:NIEMINEN JYRI

Film-forming composition and its use in the treatment of herpes

The present invention relates to a topical film-forming composition, which comprises in a pharmaceutically acceptable medium: 5-30wt% of ethyl cellulose; 0.1-10wt% of an auxiliary film-forming agent; 0.1-20wt% of one or A plurality of tribasic acids, at least one of which is boric acid; and 60-95% by weight of an organic solvent, the weight percentage is relative to the total weight of the composition. The invention also relates to the use of this composition in a method for the treatment of herpes, especially cold sores.
Owner:URGO RECH INNOVATION & DEVEMENT
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