4977 results about "Cutis" patented technology

Described herein are methods and apparatuses for reducing or eliminating skin glands (e.g., sebaceous, eccrine and apocrine) with an electric treatment. These apparatuses and methods may produce electroporation of cells by applying treatment dose having an energy density sufficient to eliminate or reduce the size of a target gland. Also described herein are methods for treating and / or preventing a disorder of a skin gland. For example, described herein are methods of treating sebaceous hyperplasia.

A process for exfoliating the skin, including the scalp, and / or the nails, comprising the step consisting in subjecting a surface of said skin (K), or said nails, to a cosmetic composition and to ultrasonic acoustic waves emitted by a device comprising at least one ultrasonic transducer (13), with an acoustic intensity Isata in the region exposed to the acoustic waves that is at least equal to 0.1 W / cm2, i) the transducer being moved relative to said surface at an average sweeping speed of between 0.01 cm2 / s and 15 cm2 / s for the duration of treatment of said surface, and / or ii) the device being applied to a location on the keratin material, then moved away from the latter and applied to a different location.

According to some embodiments, a device for treating a skin surface comprises a handpiece with an opening configured to receive a container containing a concentrated treatment fluid, a skin interface portion, configured to contact the skin surface, and a treatment fluid mixing zone within the handpiece. The mixing zone can receive concentrated treatment material from the container secured to the handpiece and dilution fluid from a dilution fluid conduit, and mix the two or more input fluids / materials to create a diluted treatment fluid to be delivered to the interface portion during use. The handpiece can include a waste fluid connection in fluid communication with the interface portion of the device and a vacuum source to draw the mixed treatment fluid to the interface portion and skin tissue, and to draw spent treatment material from the interface portion during use.

According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface. In some embodiments, the delivery conduit is configured to selectively deliver at least one time-release material to the skin surface being treated.

A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.

The invention provides a radiotherapy patient skin injury real-time detection record management system based on image processing, and belongs to the technical field of radiotherapy patient skin injury real-time detection. Comprising a multispectral image acquisition module for imaging the skin of a patient at the same visual angle by adopting different spectrums to obtain three spectral images including near-infrared imaging, infrared imaging and ultraviolet imaging; a first identification module is used for fusing three spectral images to obtain an image data set, and a second identification module is used for constructing an epidermis injury coefficient # imgabs0 #, a dermis injury coefficient # imgabs1 # and a subcutaneous injury coefficient # imgabs2 # of the ith patient and evaluating the epidermis injury coefficient # imgabs0 #, the dermis injury coefficient # imgabs1 # and the subcutaneous injury coefficient # imgabs2 # respectively. A skin injury evaluation model is constructed, the comprehensive injury area ratio is calculated, the classification of injury levels is realized, data support is provided for a personalized treatment scheme, and a powerful auxiliary diagnosis tool is provided for a medical institution.

A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.

Apparatus comprising a housing, at least one needle arranged for reciprocal motion between a retracted position and an extended position to penetrate an animal tissue surface when in the extended position, and a sealing device defining a channel through which a movable shaft extends to move the at least one needle in the reciprocating motion, wherein the sealing device serves to form a seal between the housing and the movable shaft. A corresponding method of preventing cross-contamination within apparatus for minimally invasive treatment of skin is also disclosed.

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.

Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. In an exemplary embodiment, first and second cuts are made into the reticular layer of a skin sample to separate an improved acellular dermal matrix (ACDM) which forms a dermal tissue form useful as a graft. The dermal tissue form consists essentially of reticular dermis and has a first exposed surface formed by reticular dermis, an opposite second exposed surface formed by reticular dermis, and has substantially uniform density and uniform porosity between the first and second exposed surfaces, which allows and promotes rapid and efficient cellular ingrowth and tissue ingrowth substantially equally from either the first or second exposed surfaces upon implantation.

The invention discloses a working method of skin thermal therapy equipment which is convenient to use and can realize intelligent startup work and an itching relieving instrument. According to the technical scheme, the working method of the skin thermal therapy equipment comprises the following steps that a, whether a designated area makes contact with the skin of a user or not is detected, and if yes, the step b is executed; and b, detecting the skin contact time and the skin temperature of the contacted part, and if the detected temperature is within a preset range and the continuous contact time reaches the set time, starting the skin thermal therapy equipment to operate.

Wearable modular mask systems for combination face and skincare diagnostics and therapeutics. Systems include devices that can be attached to wearable masks for diagnosis and treatment of skin conditions, diseases, and disorders, as well as for cosmetic improvements to the skin of the face and scalp.

The invention relates to a sweat real-time detection device and a preparation method thereof, the sweat real-time detection device sequentially comprises a collection layer and a detection layer from bottom to top, the collection layer comprises a fitting area, a fan-shaped flow guide area and a collection area, the fitting area is used for fitting skin, and the flow guide area is used for guiding sweat into the collection area; a plurality of guide vanes facing the collecting area are arranged in the guide area, and the guide vanes are triangular; the collecting area is connected into the fan-shaped included angle of the flow guide area and penetrates through the collecting layer; the detection layer is internally provided with a drainage area, a detection area and a micro-channel, the drainage area corresponds to the collection area and is used for draining sweat in the collection area to the detection area, and the detection area is provided with a sweat detection chip; the micro-channel is emitted from the drainage area, penetrates through the detection area and extends to the outermost side of the detection layer. The sweat collection device has the characteristics of high sweat collection efficiency, sufficient sweat collection amount, timely sweat detection after collection, rapid sweat analysis and detection process, reliable detection result and the like.

Disclosed herein are embodiments of a system and embodiments of a method for stabilizing spinal vertebrae through a skin incision. In some embodiments, the system or method can include a first screw having a first screw head, a second screw having a second screw head, and a third screw having a third screw head, a first tower having a distal portion, a proximal portion, and a bend between the distal portion and the proximal portion, a second tower having a distal portion and a proximal portion, the second tower configured to be removably coupled with the second screw at a distal end of the second tower, and a third tower having a distal portion, a proximal portion, and a bend between the distal portion and the proximal portion.

The present disclosure provides a target region positioning method, an electronic device and a computer readable storage medium, the target region positioning method comprising: acquiring, by a camera, a target image comprising a skin surface region corresponding to a reaction bone; wherein the reaction bone is a bone having a target feature; identifying the skin surface region from the target image; determining first device coordinate information of a center position of the skin surface region in a device coordinate system; determining second device coordinate information of a center position of a target region comprising a lesion in the device coordinate system according to the first device coordinate information and predetermined first position relationship information; wherein the first position relationship information is position relationship information between the center position of the skin surface region and the center position of the target region.

Methods for the use of prodrugs of itaconic acid and 1- and 4-methyl itaconic acid for inducing hair growth and treating an inflammatory, or immune activation (adaptive or innate), skin condition or other condition associated with hair loss are disclosed.

Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater than about 0.2 mm and less than about 0.7 mm or 0.5 mm, using a mechanical apparatus. Compressive and / or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and / or directional shrinkage of the treated skin area.

The invention provides a recombinant XVII type collagen with a triple helix structure, and belongs to the technical field of biological proteins. The amino acid sequence of the collagen comprises one or more amino acid residue repetitive units, each repetitive unit comprises a sequence as shown in SEQ ID NO.1 or SEQ ID NO.2, the number of repetitions is n, and n is larger than 1 and smaller than or equal to 60. The recombinant XVII type collagen provided by the invention is simple in production process, relatively high in expression quantity, low in immunogenicity, high in safety, relatively good in stability of the triple-helix structure, and strong in supporting capacity for skin cells; efficacy experiments show that the collagen has higher cell adhesion, wound healing promotion and hair follicle repair promotion capability than XVII type collagen products in the market at present, and can be widely applied to the fields of food, health care products, cosmetics, medical instruments and the like.

The invention belongs to the technical field of tissue engineering, and particularly discloses a preparation method of a 3D full-thickness skin model. The preparation method provided by the invention comprises the following steps: constructing a corium layer, constructing an inner epidermal layer through first epidermal inoculation, constructing an epidermal layer through second epidermal inoculation and obtaining a complete 3D full-thickness skin model through co-culture. The 3D full-thickness skin model obtained through the preparation method is distinct in gradation, uniform in thickness, free of shrinkage and stable in quality, the epidermal layer and the corium layer are uniformly fused, and the 3D full-thickness skin model is suitable for skin function research and sample evaluation. Meanwhile, the preparation method provided by the invention is simple in process and convenient to operate, does not need additional reagents or anti-shrinkage tools, can meet the requirements of large-scale industrial production, and has good production feasibility and market application prospects.

The invention belongs to the technical field of biological simulation, and discloses an anus cleaning effect evaluation method and system.The method comprises the steps that an execution assembly is controlled to wipe an anus anatomical structure with a to-be-detected sample according to a target wiping strategy, and a multi-mode sensing assembly is controlled to collect target parameters on the anus anatomical structure; obtaining target monitoring data; according to the residual dirt amount in the target monitoring data, a cleaning efficiency score is obtained through calculation, a target mechanical simulation model is called, according to the humidity permeation gradient value and the pressure value in the target monitoring data and the to-be-detected sample, a skin stimulation risk score is obtained through calculation, and the skin stimulation risk score and the cleaning efficiency score form a cleaning effect evaluation report. Simulation and prediction of the anus cleaning process are achieved, the simulation test effect and accuracy are greatly improved, and a cleaning effect evaluation report is given to illustrate the safety of the to-be-tested sample.

The invention provides a composition with oil-controlling, acne-removing, barrier-repairing effects and application thereof, and belongs to the field of cosmetics. The composition is prepared from a baropetalum beetle leaf extract, a roselle flower extract, totarol and a cryptomeria fortunei bud extract. The baropetalum chinense leaf extract has the effects of balancing grease secretion and shrinking pores; the roselle flower extract is rich in organic acid and anthocyanin, and has the effects of dissolving pore keratosuppository, controlling oil, resisting inflammation, smoothing acne skin, preserving moisture and removing redness; as a bacteriostatic agent, totarol has a natural preservative effect on gram-positive bacteria and partial negative bacteria, and has the effects of removing acnes, sterilizing, diminishing inflammation, whitening and the like; the cryptomeria fortunei bud extract can promote skin tissue structure regeneration and strengthen skin barriers. The composition effectively regulates and controls excessive secretion of sebaceous gland grease and pox skin specific protein through the synergistic effect of various components, promotes the health of pox skin, repairs the skin barrier and enhances the self-protection ability of the skin at the same time.

The invention belongs to the technical field of microorganisms, and particularly relates to a lactobacillus polyactis composition for improving skin as well as a derivative and application of the lactobacillus polyactis composition. The composition comprises a bacterial strain, a pure culture or an inactivated bacterium body of bifidobacterium bifidum Bbifid-1 (CCTCC NO: M2023349), bifidobacterium adolescentis Badol-1 (CCTCC NO: M 20242593), phytobacterium plantarum Lplan-4 (CCTCC NO: M 20242594) and lactobacillus acidophilus (BA05). The invention further relates to a preparation method of the composition. The lactobacillus plantarum derivative composition prepared through treatment modes of splitting decomposition, extraction, fermentation and the like can be used as an active ingredient of a medicine or a cosmetic, has remarkable effects of resisting oxidation and bacteria, especially resisting inflammation and inhibiting skin lipid accumulation aiming at propionibacterium acnes and staphylococcus aureus, is beneficial to fading skin red and swollen, avoids hair follicle blockage, and has a good application prospect. The obvious effect on the acne is realized.

The invention relates to the technical field of daily chemicals, in particular to a skin care matrix with skin micro-ecology regulating and hair loss preventing effects and cosmetics thereof. The invention discloses a skin care matrix with effects of regulating skin micro-ecology and preventing hair loss. Comprising the following components in parts by weight: 60 to 70 parts of galactose yeast-like bacterium fermentation product filtrate, 0.05 to 0.5 part of Chinese arborvitae twig and leaf extract, 0.05 to 0.5 part of citrus fruit extract, 0.05 to 0.5 part of white willow bark extract, 0.05 to 0.5 part of officinal magnolia bark extract, 0.05 to 0.5 part of lotus leaf extract, 0.05 to 0.5 part of sea buckthorn fruit extract, 0.05 to 0.1 part of ceramide NS / ceramide NG and 0.05 to 0.5 part of Italian helichrysum extract. 1.0 to 5.0 parts of lactobacillus / soybean extract fermentation product filtrate, 0.5 to 1.0 part of vitex trifolia fruit extract, 0.05 to 0.3 part of hydrolyzed keratin and 0.05 to 0.3 part of hydrolyzed vegetable protein; according to the skin care matrix, the microbial fermentation product and the plant extract are used as skin probiotics, and ceramide and other components are used as auxiliary materials to generate a synergistic effect, so that the skin care matrix shows excellent effects of balancing scalp micro-ecology, repairing hair follicles, refreshing and preventing hair loss on the premise of ensuring safety and mildness.

The invention provides a soothing and repairing composition for oil-sensitive skin and application of the soothing and repairing composition, and belongs to the technical field of cosmetics. According to the soothing and repairing composition, the hydrolyzed yeast protein, the aesculus chinensis extract, the marine oligosaccharide, the Australian tealeaf extract and the phellinus igniarius extract are compounded to form the soothing and repairing composition, and the soothing and repairing composition reduces skin discomfort by maintaining the steady state of an enzyme network of epidermis, reducing oxidase and increasing enzymes and defensive enzymes for promoting Newcastle metabolism; the effects of repairing, moisturizing, controlling oil and relieving are achieved, the skin injury of oily sensitive skin is gently repaired, and the health state of the skin is recovered.

The utility model discloses a breast surgery anti-drag hook skin scald buckle which comprises an expansion mechanism and a transmission locking mechanism, the expansion mechanism is used for expanding a surgery opening, the top of the expansion mechanism is provided with the transmission locking mechanism for locking the expansion mechanism, and the transmission locking mechanism is used for locking the expansion mechanism. The expansion mechanism comprises a first cross rod, a second cross rod, an extension assembly and a drag hook assembly, the second cross rod is arranged on one side of the first cross rod in a mirror image mode, the extension assembly comprises a first shaft rod, a first connecting rod, a second shaft rod, a third shaft rod and a second connecting rod, and the first shaft rods are fixedly connected to the two ends of the first cross rod. According to the buckle for preventing the drag hook skin from being scalded in the mammary gland operation, the expansion mechanism is arranged, after a mammary gland is cut, the buckle extends to the lower layer skin, the first transverse rod and the second transverse rod are pulled towards the two sides at the same time, the cut can be expanded, and therefore the purpose of expanding a wound can be achieved.

In some embodiments, the method can comprise locating a targeted portion of skin surface; delivering ultrasound energy to subcutaneous tissue below the skin surface; producing a biological effect in at least one of the skin surface and the subcutaneous tissue; and improving the appearance of the targeted portion of the skin surface. Improving the appearance of the skin surface can be at least one of increasing skin elasticity, reducing skin oiliness, reducing skin pore size, smoothing skin texture, reducing hyperpigmentation, treating and / or preventing acne, reducing a blemish, reducing an appearance of spider veins and / or rosacea, reducing an appearance of scars, reducing an appearance of stretch marks, rejuvenating skin, increasing collagen in the subcutaneous tissue, tightening of sagging sink, rejuvenating photoaged skin, increasing a thickness of a dermal layer, reducing a wrinkle on the skin surface, generating new tissue in the subcutaneous layer, and combinations thereof.

The invention belongs to the technical field of medical cosmetology and plastic surgery, and particularly relates to a hydroxyapatite microsphere facial skin filling agent for injection and a preparation method thereof. Hydroxyapatite microspheres and sodium hyaluronate are uniformly mixed, a cross-linking agent is added, and cross-linked sodium hyaluronate-hydroxyapatite core-shell structure microsphere particles which take hydroxyapatite microspheres as cores and cross-linked sodium hyaluronate as shells and are of a soft-in-hard structure can be obtained through dialysis and particle grading. The cross-linked sodium hyaluronate is used as a core-shell structure, so that the hydroxyapatite is locked in the cross-linked sodium hyaluronate, agglomeration is effectively avoided, the extrusion resistance can be well reduced by the soft-wrapped-hard core-shell structure, and the propulsive force is smaller. All the components in the hydroxyapatite microsphere facial skin filler for injection have better biocompatibility, so that the rejection of the filler in a body is reduced, and the skin problems of allergy, redness, swelling, small lumps and the like after injection and filling are effectively avoided.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and / or skin repositioning and / or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

The invention relates to organoid culture. The invention provides a human epidermal organoid differential medium, a method for constructing an epidermal model and application of the human epidermal organoid differential medium, the human epidermal organoid differential medium comprises a basic medium component and an additive, and the additive comprises lipid. According to the method, the organoid is directly used for constructing the epidermal model, so that the problem of few cell sources is solved; a lipid component is added into the epidermal organ differentiation culture medium, so that the epidermal organ can enhance the barrier function of the cuticle, further differentiation of the epidermal organ can be effectively promoted by utilizing the epidermal organ differentiation culture medium, and a human epidermal model with a basal layer, a spinous layer, a granular layer and a cuticle which are completely morphologically differentiated is obtained. And the operation is simple, large-batch production is easy to realize, and a reliable tool is provided for in-vitro observation, interference of skin disease generation, injury repair and other life activities.

To provide a safe, effective agent for improving skin texture.SOLUTION: It was discovered that a pharmaceutical composition having a polysulfated mucopolysaccharide such as a heparinoid, etc., or a salt thereof as an active ingredient is useful for improving skin texture or reducing a bumpy area.SELECTED DRAWING: Figure 1