3432 results about "Cutis" patented technology

A process for exfoliating the skin, including the scalp, and / or the nails, comprising the step consisting in subjecting a surface of said skin (K), or said nails, to a cosmetic composition and to ultrasonic acoustic waves emitted by a device comprising at least one ultrasonic transducer (13), with an acoustic intensity Isata in the region exposed to the acoustic waves that is at least equal to 0.1 W / cm2, i) the transducer being moved relative to said surface at an average sweeping speed of between 0.01 cm2 / s and 15 cm2 / s for the duration of treatment of said surface, and / or ii) the device being applied to a location on the keratin material, then moved away from the latter and applied to a different location.

The invention provides a radiotherapy patient skin injury real-time detection record management system based on image processing, and belongs to the technical field of radiotherapy patient skin injury real-time detection. Comprising a multispectral image acquisition module for imaging the skin of a patient at the same visual angle by adopting different spectrums to obtain three spectral images including near-infrared imaging, infrared imaging and ultraviolet imaging; a first identification module is used for fusing three spectral images to obtain an image data set, and a second identification module is used for constructing an epidermis injury coefficient # imgabs0 #, a dermis injury coefficient # imgabs1 # and a subcutaneous injury coefficient # imgabs2 # of the ith patient and evaluating the epidermis injury coefficient # imgabs0 #, the dermis injury coefficient # imgabs1 # and the subcutaneous injury coefficient # imgabs2 # respectively. A skin injury evaluation model is constructed, the comprehensive injury area ratio is calculated, the classification of injury levels is realized, data support is provided for a personalized treatment scheme, and a powerful auxiliary diagnosis tool is provided for a medical institution.

A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.

Apparatus comprising a housing, at least one needle arranged for reciprocal motion between a retracted position and an extended position to penetrate an animal tissue surface when in the extended position, and a sealing device defining a channel through which a movable shaft extends to move the at least one needle in the reciprocating motion, wherein the sealing device serves to form a seal between the housing and the movable shaft. A corresponding method of preventing cross-contamination within apparatus for minimally invasive treatment of skin is also disclosed.

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.

The invention discloses a working method of skin thermal therapy equipment which is convenient to use and can realize intelligent startup work and an itching relieving instrument. According to the technical scheme, the working method of the skin thermal therapy equipment comprises the following steps that a, whether a designated area makes contact with the skin of a user or not is detected, and if yes, the step b is executed; and b, detecting the skin contact time and the skin temperature of the contacted part, and if the detected temperature is within a preset range and the continuous contact time reaches the set time, starting the skin thermal therapy equipment to operate.

Wearable modular mask systems for combination face and skincare diagnostics and therapeutics. Systems include devices that can be attached to wearable masks for diagnosis and treatment of skin conditions, diseases, and disorders, as well as for cosmetic improvements to the skin of the face and scalp.

The present disclosure provides a target region positioning method, an electronic device and a computer readable storage medium, the target region positioning method comprising: acquiring, by a camera, a target image comprising a skin surface region corresponding to a reaction bone; wherein the reaction bone is a bone having a target feature; identifying the skin surface region from the target image; determining first device coordinate information of a center position of the skin surface region in a device coordinate system; determining second device coordinate information of a center position of a target region comprising a lesion in the device coordinate system according to the first device coordinate information and predetermined first position relationship information; wherein the first position relationship information is position relationship information between the center position of the skin surface region and the center position of the target region.

The invention belongs to the technical field of tissue engineering, and particularly discloses a preparation method of a 3D full-thickness skin model. The preparation method provided by the invention comprises the following steps: constructing a corium layer, constructing an inner epidermal layer through first epidermal inoculation, constructing an epidermal layer through second epidermal inoculation and obtaining a complete 3D full-thickness skin model through co-culture. The 3D full-thickness skin model obtained through the preparation method is distinct in gradation, uniform in thickness, free of shrinkage and stable in quality, the epidermal layer and the corium layer are uniformly fused, and the 3D full-thickness skin model is suitable for skin function research and sample evaluation. Meanwhile, the preparation method provided by the invention is simple in process and convenient to operate, does not need additional reagents or anti-shrinkage tools, can meet the requirements of large-scale industrial production, and has good production feasibility and market application prospects.

The invention belongs to the technical field of biological simulation, and discloses an anus cleaning effect evaluation method and system.The method comprises the steps that an execution assembly is controlled to wipe an anus anatomical structure with a to-be-detected sample according to a target wiping strategy, and a multi-mode sensing assembly is controlled to collect target parameters on the anus anatomical structure; obtaining target monitoring data; according to the residual dirt amount in the target monitoring data, a cleaning efficiency score is obtained through calculation, a target mechanical simulation model is called, according to the humidity permeation gradient value and the pressure value in the target monitoring data and the to-be-detected sample, a skin stimulation risk score is obtained through calculation, and the skin stimulation risk score and the cleaning efficiency score form a cleaning effect evaluation report. Simulation and prediction of the anus cleaning process are achieved, the simulation test effect and accuracy are greatly improved, and a cleaning effect evaluation report is given to illustrate the safety of the to-be-tested sample.

The invention provides a composition with oil-controlling, acne-removing, barrier-repairing effects and application thereof, and belongs to the field of cosmetics. The composition is prepared from a baropetalum beetle leaf extract, a roselle flower extract, totarol and a cryptomeria fortunei bud extract. The baropetalum chinense leaf extract has the effects of balancing grease secretion and shrinking pores; the roselle flower extract is rich in organic acid and anthocyanin, and has the effects of dissolving pore keratosuppository, controlling oil, resisting inflammation, smoothing acne skin, preserving moisture and removing redness; as a bacteriostatic agent, totarol has a natural preservative effect on gram-positive bacteria and partial negative bacteria, and has the effects of removing acnes, sterilizing, diminishing inflammation, whitening and the like; the cryptomeria fortunei bud extract can promote skin tissue structure regeneration and strengthen skin barriers. The composition effectively regulates and controls excessive secretion of sebaceous gland grease and pox skin specific protein through the synergistic effect of various components, promotes the health of pox skin, repairs the skin barrier and enhances the self-protection ability of the skin at the same time.

The invention belongs to the technical field of microorganisms, and particularly relates to a lactobacillus polyactis composition for improving skin as well as a derivative and application of the lactobacillus polyactis composition. The composition comprises a bacterial strain, a pure culture or an inactivated bacterium body of bifidobacterium bifidum Bbifid-1 (CCTCC NO: M2023349), bifidobacterium adolescentis Badol-1 (CCTCC NO: M 20242593), phytobacterium plantarum Lplan-4 (CCTCC NO: M 20242594) and lactobacillus acidophilus (BA05). The invention further relates to a preparation method of the composition. The lactobacillus plantarum derivative composition prepared through treatment modes of splitting decomposition, extraction, fermentation and the like can be used as an active ingredient of a medicine or a cosmetic, has remarkable effects of resisting oxidation and bacteria, especially resisting inflammation and inhibiting skin lipid accumulation aiming at propionibacterium acnes and staphylococcus aureus, is beneficial to fading skin red and swollen, avoids hair follicle blockage, and has a good application prospect. The obvious effect on the acne is realized.

The invention provides a soothing and repairing composition for oil-sensitive skin and application of the soothing and repairing composition, and belongs to the technical field of cosmetics. According to the soothing and repairing composition, the hydrolyzed yeast protein, the aesculus chinensis extract, the marine oligosaccharide, the Australian tealeaf extract and the phellinus igniarius extract are compounded to form the soothing and repairing composition, and the soothing and repairing composition reduces skin discomfort by maintaining the steady state of an enzyme network of epidermis, reducing oxidase and increasing enzymes and defensive enzymes for promoting Newcastle metabolism; the effects of repairing, moisturizing, controlling oil and relieving are achieved, the skin injury of oily sensitive skin is gently repaired, and the health state of the skin is recovered.

The utility model discloses a breast surgery anti-drag hook skin scald buckle which comprises an expansion mechanism and a transmission locking mechanism, the expansion mechanism is used for expanding a surgery opening, the top of the expansion mechanism is provided with the transmission locking mechanism for locking the expansion mechanism, and the transmission locking mechanism is used for locking the expansion mechanism. The expansion mechanism comprises a first cross rod, a second cross rod, an extension assembly and a drag hook assembly, the second cross rod is arranged on one side of the first cross rod in a mirror image mode, the extension assembly comprises a first shaft rod, a first connecting rod, a second shaft rod, a third shaft rod and a second connecting rod, and the first shaft rods are fixedly connected to the two ends of the first cross rod. According to the buckle for preventing the drag hook skin from being scalded in the mammary gland operation, the expansion mechanism is arranged, after a mammary gland is cut, the buckle extends to the lower layer skin, the first transverse rod and the second transverse rod are pulled towards the two sides at the same time, the cut can be expanded, and therefore the purpose of expanding a wound can be achieved.

The invention belongs to the technical field of medical cosmetology and plastic surgery, and particularly relates to a hydroxyapatite microsphere facial skin filling agent for injection and a preparation method thereof. Hydroxyapatite microspheres and sodium hyaluronate are uniformly mixed, a cross-linking agent is added, and cross-linked sodium hyaluronate-hydroxyapatite core-shell structure microsphere particles which take hydroxyapatite microspheres as cores and cross-linked sodium hyaluronate as shells and are of a soft-in-hard structure can be obtained through dialysis and particle grading. The cross-linked sodium hyaluronate is used as a core-shell structure, so that the hydroxyapatite is locked in the cross-linked sodium hyaluronate, agglomeration is effectively avoided, the extrusion resistance can be well reduced by the soft-wrapped-hard core-shell structure, and the propulsive force is smaller. All the components in the hydroxyapatite microsphere facial skin filler for injection have better biocompatibility, so that the rejection of the filler in a body is reduced, and the skin problems of allergy, redness, swelling, small lumps and the like after injection and filling are effectively avoided.

The invention relates to organoid culture. The invention provides a human epidermal organoid differential medium, a method for constructing an epidermal model and application of the human epidermal organoid differential medium, the human epidermal organoid differential medium comprises a basic medium component and an additive, and the additive comprises lipid. According to the method, the organoid is directly used for constructing the epidermal model, so that the problem of few cell sources is solved; a lipid component is added into the epidermal organ differentiation culture medium, so that the epidermal organ can enhance the barrier function of the cuticle, further differentiation of the epidermal organ can be effectively promoted by utilizing the epidermal organ differentiation culture medium, and a human epidermal model with a basal layer, a spinous layer, a granular layer and a cuticle which are completely morphologically differentiated is obtained. And the operation is simple, large-batch production is easy to realize, and a reliable tool is provided for in-vitro observation, interference of skin disease generation, injury repair and other life activities.

To provide a safe, effective agent for improving skin texture.SOLUTION: It was discovered that a pharmaceutical composition having a polysulfated mucopolysaccharide such as a heparinoid, etc., or a salt thereof as an active ingredient is useful for improving skin texture or reducing a bumpy area.SELECTED DRAWING: Figure 1

The invention discloses a sweat in-situ detection sensor based on a microneedle patch and a preparation method of the sweat in-situ detection sensor, and belongs to the technical field of sweat detection. The sweat in-situ detection sensor comprises a flexible substrate, and the flexible substrate comprises a hydrophobic layer used for being in contact with skin; the hydrophilic layer is arranged on the hydrophobic layer, and the sweat contact angle of the hydrophilic layer is smaller than that of the hydrophobic layer; the micro-channel layer comprises a micro-needle patch, and the micro-needle patch is arranged on the side, away from the hydrophobic layer, of the hydrophilic layer; the aggregation layer is arranged on the side, away from the hydrophilic layer, of the microneedle patch; the detection electrode is arranged between the aggregation layer and the microneedle patch; the volatilization layer is arranged on the side, away from the microneedle patch, of the aggregation layer, the problems that according to an existing wearable sweat detection sensor, the sweat utilization rate is not saturated, sweat is accumulated and flows back, a trace amount of sweat is difficult to fully utilize, and the detection precision of physiological signals is affected can be solved, and the application potential is huge.

The utility model discloses a multidirectional adjustable skin tension reducing device, which belongs to the technical field of skin tension reducing devices, and adopts the technical scheme that the multidirectional adjustable skin tension reducing device comprises two patches, the tops of the patches are fixedly connected with a fixing strip, a plurality of adjusting mechanisms are arranged in the fixing strip; the adjusting mechanism comprises a sliding block, a rubber soft cushion and a pull strip, the bottom of the sliding block makes contact with the top of the patch, the side, close to the sliding block, of the rubber soft cushion is fixedly connected with the sliding block, and the side, close to the rubber soft cushion, of the pull strip penetrates through the rubber soft cushion and is fixedly connected with the surface of the sliding block; the skin tension reducing device solves the problems that roots of braces of most existing skin tension reducing devices are integrated with patches, after the patches are attached to the surfaces of skin wounds, the density of the braces is inconvenient to move and adjust in multiple directions according to needs, the density of the braces is inconvenient to adjust according to different positions of skin tension, use is limited, and the skin tension reducing effect is poor. Therefore, the use effect is influenced.

The invention provides a hair follicle transplantation method and system, a program unit, a storage medium and a program product, and the method comprises the steps: enabling a tensioner to apply downward pressure to the skin, driving a first tensioning part and a second tensioning part to be away from each other, and expanding the skin to form an expanded skin region; the system comprises a mechanical arm tail end tool, the mechanical arm tail end tool moves, gets close to an expanded skin area and executes a hair follicle transplantation task, the system further comprises a controller, the controller evaluates hair follicle transplantation parameters and formulates a hair follicle transplantation plan, and in a hair follicle transplantation mode, the controller controls the mechanical arm tail end tool to perform incision at a transplantation part in a manner that the incision direction and / or depth can be controlled. And the blocking device keeps the hair follicle at the required depth, and the mechanical arm tail end tool is retracted to complete the transplantation task. According to the application, the tensioner can be automatically controlled to tension the scalp or loosen the scalp, the tensioning degree of the scalp can be adjusted, the needling depth, the needling angle and the needling density are adjusted according to the obtained tensioning degree of the scalp, the batch consistency of extracted hair follicles is improved, and the hair follicle transplantation effect is improved.

Systems for producing a cosmetic effect in skin tissue of a patient are provided. The systems include a treatment module and an actuation assembly. The treatment module includes at least one coring element configured to remove a portion of skin tissue when the coring element is inserted into and withdrawn from the skin tissue. The actuation assembly is operably attached to the treatment module and can translate and / or actuate the treatment module in one or more directions relative to a surface of the skin tissue. The system can perform a microcoring procedure that provides a cosmetic effect to the patient. Methods of performing a microcoring procedure are also provided.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and / or skin repositioning and / or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

Disclosed herein is a catheter, which in some embodiments includes a distal section configured to enter a skin insertion site. The distal section can include a tapered junction having one or more dilation structures configured to dilate the skin insertion site. The distal section can further include a distal portion extending from a distal end of the tapered junction, the distal portion having a diameter smaller than a proximal portion of the catheter. In combination, the tapered junction, the one or more dilation structures, and the specific actions of the user urging the catheter into the insertion site can result in an improved fit of the catheter in the insertion site.

The invention relates to an external composition for hair growth regulation and a preparation method thereof, and belongs to the technical field of cosmetics and medicines. The composition disclosed by the invention comprises nano mesoporous carbon for enhancing permeation, various surface functional modifications on the nano mesoporous carbon, minoxidil, protein fragments, polypeptides, oligopeptides, amino acids, dutasteride, bimatoprost, traditional Chinese medicine extracts, vitamins, caffeine, nucleosides, growth factors and various auxiliary functional components. Wherein the pore diameter of mesopores of the nano mesoporous carbon for enhancing permeation is 2-30 nm, the total pore volume of the mesopores is 1.5-3.5 cm < 3 > / g, and the particle size of the nano mesoporous carbon is 50-200 nm. The prepared nano mesoporous carbon is granular, controllable in size, stable in structure, free of irritation to skin, capable of keeping inert to various active ingredients in the composition, capable of enhancing absorption and permeation of other ingredients on the skin, wide in application range, capable of compounding various types of active ingredients and high in biological safety.

The invention relates to application of a platelet reaction protein 4 in preparation of an alopecia medicine, and belongs to the field of medical biology. The invention aims to solve the technical problems of limited curative effect, obvious side effect and narrow application range of the existing alopecia treatment medicine. The invention provides an application of a platelet reaction protein 4 (THBS4) in preparation of an alopecia medicinal preparation, which can promote hair follicles to be converted from a resting period to a growing period by regulating and controlling a mechanical microenvironment around the hair follicles, enhancing the interaction between fibroblasts and hair follicle stem cells and activating regeneration signal channels in hair papilla and hair bud areas. The traditional Chinese medicine composition breaks through the limitation that existing treatment only aims at specific alopecia types, and can be widely applied to various alopecia diseases such as androgenetic alopecia, pressure alopecia and alopecia after chemotherapy. And compared with the traditional medicine, the traditional Chinese medicine composition has the advantages of quick response, no skin irritation reaction and improved hair follicle regeneration efficiency, and provides a brand new solution for safe and efficient treatment of alopecia.

The invention discloses a preparation method and application of a recombinant XVII type collagen and adenosine eutectic substance. According to the invention, adenosine and recombinant XVII type collagen are combined through a non-covalent bond to form a novel supramolecular eutectic substance. The solubility and skin permeability of the eutectic substance are improved through the synergistic effect of the two substances, and the performance of fixing hair and promoting hair papilla cell proliferation is also enhanced.

To provide a phototherapeutic apparatus capable of preventing burns without reducing treatment effects even on the skin with a lentigo, body hair and the like.SOLUTION: A phototherapeutic apparatus comprises: a light irradiation part that applies a beam to the skin which is an irradiation region; a cooling part that cools the irradiation region when the beam is applied by the light irradiation part; a skin color information acquisition part that acquires skin color information on the irradiation region; and a cooling intensity adjustment part that adjusts cooling intensity of the cooling part on the basis of details of the acquired skin color information.SELECTED DRAWING: Figure 1

The invention discloses a novel application of bifidobacterium longum subsp. Infantis CCFM1269 in relieving atopic dermatitis, and belongs to the technical field of microorganisms. The bifidobacterium longum subsp. Infantis CCFM1269 provided by the invention can relieve atopic dermatitis, and is specifically reflected in that (1) ear swelling and back skin thickening of mice are relieved, dermatological symptoms are relieved, and mast cell infiltration is reduced; (2) reducing the total IgE level of serum; (3) the Treg level of mesenteric lymph nodes and the ILA content of serum are improved; (4) IL-4 and TSLP levels in skin tissues are reduced, IL-10 is improved, and Th1 / Th2 immune balance is recovered; (5) improving AHR and CYP1A1 in the skin tissue; and (4) high yield of ILA.

The invention discloses a barrier repair composition applicable to dry sensitive skin and application thereof. The composition comprises a golden camellia extract, a loquat leaf extract, an alfalfa extract and hydrolyzed royal jelly protein. According to the barrier repairing composition applicable to the dry sensitive skin, disclosed by the invention, through reasonable matching and synergistic interaction of all the components, a better skin barrier repairing effect can be achieved, so that the problems of dry and tight skin, desquamation, erythema, itching, dull luster, redness, burning heat sensation, pricking pain and the like of the dry sensitive skin are fundamentally solved.

Electric shaver (1) having a main body (3) and a shaving unit (5) coupled to the main body. The shaving unit has three hair-cutting units (9a, 9b, 9c) each having an external cutting member (11) with a skin-contact surface (13) with hair-entry openings (15) and an internal cutting member (17) which is rotatable relative to the external cutting member. The hair-cutting units each have at least one geometric parameter (w) that influences a hair-cutting process of each individual hair-cutting unit. The shaving unit can be positioned relative to the main body in at least two different angular positions about a central axis (37) of the shaving unit. A value of the geometric parameter of at least one of the hair-cutting units is different from the values of the geometric parameter of the other hair-cutting units.