368 results about "Cutis" patented technology

The application relates to the technical field of medical treatment, and provides a dermatological sampler, which comprises a sampling seat, the bottom end of the sampling seat is provided with a pushing part, the top end of the sampling seat is provided with a closing part, the closing part is provided with a first sampling rod, the top end of the sampling seat is externally sleeved with a sampling cover, the sampling cover is provided with a first sampling hole in the upper portion, the top end of the first sampling rod penetrates the first sampling hole upwards, the inside of the sampling seat is provided with a sampling cavity, the cavity bottom of the sampling cavity is connected with a second sampling rod, the sampling cover is provided with a second sampling hole, the top end of the second sampling rod penetrates the second sampling hole upwards, the closing part is provided with a third sampling hole, sampling action is realized by the first sampling rod contacting and rubbing back and forth on the skin, discomfort of the affected area is reduced, the structure is simple, sampling can be reasonably collected into a closed environment, and the operation is simple.

The present application belongs to the technical field of ostomy base plate, and particularly relates to a leakage-proof ostomy base plate for postoperative colorectal cancer, which comprises a suction cup, the upper side wall of the suction cup is fixedly connected with a connecting cylinder, the outer wall of the connecting cylinder is fixedly sleeved with two limiting rings matched with an ostomy bag, the outer wall of the suction cup is fixedly sleeved with an adhesive layer, the inner wall of the connecting cylinder is fixedly connected with an elastic film, and a center hole is formed in the center position of the elastic film. Before the ostomy base plate is used, the size and shape of the center hole of the ostomy base plate can be freely adjusted according to the use condition, so that the leakage risk of excrement caused by the size deviation of the manually cut traditional fixed circular center hole is avoided, the compression damage of the ostomy mucosa caused by the too small cutting is eliminated, the sealing property of the base plate and the skin around the ostomy is improved, the complications such as fecal dermatitis are reduced, the nursing operation difficulty is reduced, and the wearing comfort and the life quality of the patient are improved.

To provide a skin treatment apparatus for remodeling the face shape using multi-frequency RF energy and a control method thereof for performing skin treatment using the RF energy having various frequencies different in RF energy delivery depth in tissue.SOLUTION: A skin treatment apparatus for remodeling the face shape using RF energy comprises: a main body comprising an RF generator and an RF modulator; a handpiece connected to the main body, and comprising an electrode at one side to allow the RF energy received from the main body to be delivered to skin; and a controller controlling the RF modulator to allow the RF energy having multiple frequencies to be delivered.SELECTED DRAWING: Figure 2

This utility model relates to a surgical skin-cutting device, belonging to the field of medical device technology. It solves the problems of uneven incisions, increased patient injury, and prolonged surgery time caused by the use of flat scalpels in existing skin-cutting surgeries. This utility model includes a cutting unit and a handle unit. The cutting unit includes a first blade and a second blade, both of which are fixedly connected to the handle unit. Both the first and second blades are arc-shaped, and their ends are fixedly connected. The surgical skin-cutting device of this utility model features arc-shaped first and second blades, with their ends fixedly connected. The first and second blades can simultaneously make a regular, continuous arc-shaped incision on the skin in one operation, resulting in a smooth incision, avoiding unnecessary damage to the patient, simplifying the surgical procedure, and shortening the operation time.

Provided herein are compositions, methods, kits, and devices for the treatment of skin diseases. Also provided herein are isolated and purified bacteria, excipients, carriers, dosage forms and routes of administration for such bacteria. Furthermore, provided herein are isolated and purified mixtures of bacteria, excipients, carriers, dosage forms and routes of administration for such mixtures. Also provided herein are conditions for treatment with bacteria and bacterial mixtures.

This invention discloses a composition with whitening and freckle-removing effects, its preparation method, and its application, belonging to the field of composition technology. The composition provided by this invention reduces the body's oxidative stress level, providing a suitable internal microenvironment for the efficacy of various drugs and the repair of damage; it provides a sufficient, diverse, and easily absorbed material basis for skin damage repair; it significantly improves the whitening and freckle-removing effect by increasing the activity, purity, and content of the components that directly have whitening and freckle-removing effects; and it promotes the excretion of metabolic waste by improving gastrointestinal health. It is extremely safe, requires minimal equipment, and is environmentally friendly, making it suitable for daily skin repair and whitening / freckle-removing edible use.

A method for inserting a puncture device through the skin of a subject includes the steps of: applying a skin cover unit to the skin of the subject at the puncture site; imaging the anatomical structures and / or the puncture device beneath the skin of the subject at or near the puncture site using an ultrasound probe on the upper side of the base in a distal direction; and inserting the puncture device at the puncture site.

The article relating to this design is a nasogastric tube fixing device for guiding a nasogastric tube inserted into the nostril to the side of the patient's face and holding it in place. As shown in Reference Figure 3, which illustrates the state of use, the nasogastric tube is fitted into fixing grooves extending from the center of the main body in the left and right directions, and the ends of the main body are attached to the cheek area with fixing tape, so that the nasogastric tube is held in a state that makes it difficult to come off. Also, as shown in Reference Figures 2 and 3, which illustrate the state of use, elongated holes are formed at both ends of the main body, which also serve as retainers, and the device can also be used in a form in which a separate band is connected to these elongated holes and attached around the head. When using the band, it can be fixed without using fixing tape alone, and the device is designed to be easy to use with consideration for skin irritation, and it can also be used to hold the tube securely even when adhesion is difficult due to the shape of the area under the nose, such as when there is a beard or when there are no front teeth.

The application discloses a skin tension device suitable for thoracentesis, and relates to the technical field of thoracentesis. The tension device comprises a base, a moving stretching component, a thoracentesis limiting component, an angle adjusting device and a supporting device. When working, a patient sits on the base, the height of the base can be adjusted according to the height of the patient, and the supporting device can provide suitable back support for the patient. After the patient sits down, medical staff drives the angle adjusting device to adjust the whole thoracentesis tension device to a suitable angle of the thoracic cavity area to be punctured of the patient, then the moving stretching component generates a moderate tension on the skin, and the skin at the puncture site is taut, thereby creating good conditions for subsequent puncture operation. Meanwhile, the thoracentesis limiting component can preliminarily guide and limit the direction and depth of the puncture needle. The skin is taut through the moving stretching component, and the application has the effect of meeting different puncture requirements.

The application relates to the technical field of biological medicines, in particular to a deer horn stem cell exosome as well as a preparation method and application thereof. The preparation method of the deer horn stem cell exosome comprises the following steps: S1, preparing P3-P5 generation deer horn stem cells; S2, preparing induced culture supernatant; S3, preparing crude extracted exosomes; and S4, preparing deer horn stem cell exosomes. The prepared deer horn stem cell exosome has high yield, high biological activity, can significantly promote fibroblast proliferation and collagen synthesis. Meanwhile, the exosome can effectively accelerate wound healing, has high 14d healing rate, can significantly increase the water content of the cutin layer of the skin, reduce the TEWL value, and improve the skin barrier function, provides high-quality raw materials for the research and development of skin repair products, and has a wide application prospect.

This utility model relates to the field of negative pressure drainage technology, specifically a portable negative pressure drainage device, comprising a negative pressure source instrument, a dressing, and a drainage component. The negative pressure source instrument and the dressing are connected and cooperate through the drainage component to form a negative pressure environment to absorb fluid flowing from the patient's skin. The dressing includes a sponge layer, a baffle, and an adhesive layer. The adhesive layer adheres to the patient's skin, and the baffle corresponds to the wound area of ​​the patient's skin. The side of the baffle facing the patient's skin is used to place wet dressing medication, and the side of the baffle away from the patient is connected to the sponge layer. A gap exists between the side of the baffle facing the patient's skin and the patient's skin. The baffle is provided with ventilation holes to connect the gap between the sponge layer, the baffle, and the patient's skin. The sponge layer is used to absorb bodily fluids flowing from the patient's skin. This utility model utilizes the gap between the baffle and the patient's skin to reduce tearing of the patient's wound skin when changing or removing the dressing, thereby reducing the patient's pain.

In some embodiments, the catheters disclosed herein include a distal section of the catheter configured to enter a skin insertion site. The distal section includes a taper junction including one or more expansion structures configured to expand the skin insertion site. The distal section further includes a distal portion extending from the distal end of the taper junction. The distal portion has a smaller diameter than the proximal portion of the catheter. In combination, the taper junction, the one or more expansion structures, and specific user actions that urge the catheter into the skin insertion site can enhance the fit of the catheter at the insertion site.

This invention provides an enterostomy protection device, comprising a collection bag, a protective cover, and a buffer assembly. In use, an adhesive plate is attached to the patient's abdominal skin, and the enterostomy passes through a first opening within the collection bag and protective cover. This allows secretions from the enterostomy to flow into the collection bag, facilitating their collection and reducing the risk of infection. The protective cover protects the enterostomy from scratches, pressure, and other damage. When the protective cover is subjected to external force and moves closer to the patient's abdomen, this movement causes a connecting post to move along a guide hole. This movement of the connecting post compresses a limiting plate against a buffer spring, which in turn buffers the force acting on the protective cover. This reduces the force transmitted to the patient's abdomen when the protective cover is subjected to external force, thereby reducing the risk of tearing at the suture between the abdominal wall and intestines and improving the protective effect.

1. Name of the product in this design: Applicator (03). 2. Purpose of this design: For disinfection of skin or wounds. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The present invention relates to a microneedle structure and a composition thereof that can effectively deliver a drug locally or systemically within the body by penetrating the dermis layer through the transdermis without causing damage to the skin by including a biodegradable composition containing a drug and hyaluronidase.

This invention provides an application of a quantitative partial reprogramming system in the preparation of drugs to reverse skin aging, belonging to the fields of regenerative medicine and medical aesthetics. The quantitative partial reprogramming system includes a nucleic acid delivery system or a small molecule induction system; skin aging includes photoaging-induced skin aging; reversing skin aging includes increasing the thickness of the dermis, increasing the density of type I collagen, and improving skin elasticity. The quantitative partial reprogramming system provided by this invention can fundamentally reverse the cellular aging clock and achieve structural regeneration, and can be applied to the preparation of drugs to reverse skin aging.

This invention relates to the use of skin beneficiaries for restoring the barrier function of the skin, even when the skin is exposed to stress / pollution, wherein the skin beneficiary is selected from moringa oil, farnesol, activators of peroxisome proliferator-activated receptors, and mixtures thereof; and wherein the skin beneficiary is applied to the skin at the end of the day from about 5 pm to about 12 am.

The present invention generally relates to the field of skin care. More particularly, the invention relates to a cosmetic or therapeutic skin care composition comprising live bacteria of at least one Cutibacterium acnes (C. acnes) strain in combination with a solubilizer that specifically supports their viability during storage and / or their ability to replicate after application to the skin. Preferably, the cosmetic or therapeutic skin care composition comprises bacteria of at least one C. acnes strain selected from the group consisting of D1, A5, C1, C3, H1, H2, H3, K1, K2, K4, K6, K8, K9, L1, and F4. The invention also provides a method for treating or preventing acne by applying the skin care composition of the invention to a skin area in need of treatment. The invention also relates to the use of a skin care composition of the invention for treating or preventing acne.

The invention relates to a medical skin care device (10) comprising a contact surface (111) capable of performing a skin analysis by bringing the contact surface into contact with the skin in order to detect at least one skin flaw on the skin and to determine at least one treatment method for treating the detected skin flaw. Thus, it is innovative in that it comprises: at least one sensor unit (112) located on the contact surface (111), allowing at least one skin data to be measured on the skin surface and under the skin when in contact with the skin; a processor unit (113) providing as an output information about a skin flaw on the skin and a method of treatment of the skin flaw by applying the skin data received from the sensor unit (112) as an input to the mathematical model, when the mathematical model receives the skin data trained by the skin flaws and the treatment methods of the skin flaws as input, the mathematical model generates output related to the skin flaws and the treatment methods of the skin flaws; and a treatment unit (114) that treats the skin on the basis of the skin defect treatment method information obtained from the processor unit (113).

Cosmetic hydrocolloid skin patch — 12-shade grid

The present application provides a kind of oil composition, containing monounsaturated fatty acid, polyunsaturated fatty acid, monounsaturated fatty acid is omega-9 fatty acid;Polyunsaturated acid is the mixture of omega-6 fatty acid and omega-3 fatty acid.The present application can repair and resist aging, all-purpose skin care, increase epidermal thickness, enhance barrier, anti-inflammatory soothing, anti-wrinkle firming, soothing repair red, nourish skin, and can be applied to sensitive skin, can inhibit LPS-induced HaCaT cell IL-6 secretion, increase the thickness of 3D skin model epidermis layer, and can promote the expression of silk aggregate protein (FLG), ceramide synthase 3 (CerS3), desmoglein core glycoprotein (DSG1) which has important role for skin barrier function, indicating that it can alleviate the inflammatory response produced by LPS stimulation HaCaT cell and has enhanced skin barrier function.

This application belongs to the field of image processing and relates to a skin extraction method and system. The method includes: performing nonlinear regression fitting on the prior anatomical features of skin tissue in historical oral images to obtain a skin cutting threshold; acquiring a CBCT image of the oral cavity to be processed; extracting boundary features from the cross-sectional image layers of the CBCT image to be processed based on the skin cutting threshold to obtain a dynamic candidate masking region feature map; applying inter-layer geometric consistency constraints to the dynamic candidate masking region feature map to generate a target skin masking region; extracting the original pixel values ​​within the target skin masking region and suppressing their background values; performing isosurface evolution processing on the suppressed original pixel values ​​to generate an isosurface grid; and performing patch validity screening on the isosurface grid to generate the skin extraction result. This application can reduce the interference of irrelevant data on the extraction result during the skin extraction process and ensure the quality of skin tissue extraction as much as possible.

This invention relates to a sprayable hair care product in the form of an oil-in-water emulsion, having a pH value of 3.0 to 7.0 at 20°C, comprising at least one water-insoluble oil component (A), at least one nonionic emulsifier (B), at least one nonionic co-emulsifier (C), water, and a buffer system for stabilizing the pH value, wherein the water content is equal to 60 to 90% by weight, component (A) is provided in an amount of 1.5 to 20% by weight, and components (B) and (C) are provided in a total amount of 1 to 12% by weight. The invention is characterized in that adenosine is provided in an amount of 0.01 to 3% by weight, and urea and / or urea derivatives are provided in a total amount of 1.0 to 25% by weight. This invention also relates to a method for preparing a sprayable aqueous formulation of adenosine, wherein an aqueous solution of adenosine is mixed with a finely dispersed emulsion of an oil component (A) such that the formulation contains 1.5 to 20% by weight of the emulsified oil component (A), wherein the average droplet diameter of the oil component (A) (measured using a device based on the principle of quasi-elastic light scattering (Zetasizer Nano ZS, 25°C, square polystyrene cuvette, 12 mm side length (model DTS0012), dilution: 0.025% w / w in water)) is less than 1 μm. During or after preparation and before mixing with the adenosine solution, the emulsion is brought to a phase transition temperature, and urea and / or urea derivatives are added to the resulting mixture at room temperature. This invention also relates to the use of a sprayable aqueous formulation containing adenosine and urea and / or urea derivatives with an ethanol content of less than 18% by weight for cosmetic treatment of the skin, particularly the scalp.

This invention relates to the field of puncture surgery technology and provides a skin fixation device for puncture surgery, comprising: an adhesive component, a ball-and-column clamping component, a ball-and-column, and a needle fixation component. The adhesive component is adhered to the skin surface for fixation by the adhesive's stickiness. The ball-and-column clamping component is connected to the adhesive component and is used to fix the ball-and-column and adjust its direction. The ball-and-column works in conjunction with the ball-and-column clamping component to adjust the direction of the ball joint and support the puncture instrument. The needle fixation component is located at the end of the ball-and-column for effective fixation of the end of the puncture instrument. The spherical design solves the problem of directional adjustability, while the conveniently detachable integrated C-shaped structure removes restrictions on the combination of puncture instruments and the device. The addition of a quick-release structure at the device's own joint fixation point makes the instrument more convenient and flexible to use. This device satisfies the doctor's requirement for quick disassembly and also allows for real-time switching between fixation and adjustability.

The utility model discloses a kind of excrement collecting devices, it relates to medical instrument technical field.The excrement collecting device includes flexible band-shaped collecting bag, its one side is provided with the insertion tube being communicated with the inside of collecting bag, the distal end of the insertion tube is equipped with the anti-drop ring of expansion, for inserting into patient anus and being clamped by anti-drop ring anal inner wall;The collecting bag is provided with adhesive layer in the surrounding area of insertion tube, for adhering to the skin of patient anal periphery;Collecting bag body is provided with at least two groups of sealing strips along length direction interval, and the sealing strip is horizontally through bag body two sides;Sealing strip is in initial state for open state to make collecting bag internal communication, when needing sectional sealing, by closing two adjacent sealing strips at target position, and cutting bag body between two sealing strips, to separate lower bag body containing stored excrement.The excrement collecting device can take down stored defecation as required.

The essential oil from Litsea species can be used as a preservative in cleansing compositions for the hair, skin or scalp, in laundry detergent compositions or in hard surface cleaning compositions.