32 results about "Fractional laser" patented technology

Methods of treating tissue with fractional laser radiation are disclosed. The fractional laser treatment methods reversibly increase skin permeability while maintaining a substantially intact stratum corneum and producing alterations within the epidermis and dermis. The alterations in the epidermis and dermis can include necrosis and / or coagulation. The alterations in the epidermis can include the creation of a plurality of pores in the stratum corneum and / or the creation of vacuoles in the layers of the epidermis below the stratum corneum. The fractional laser treatment methods disclosed herein can be used to provide treatments to the skin, to increase permeation of active substances into or through tissue, to deliver active substances locally or systemically, and to control the delivery of active substances.

A method and device for delivering active substances into and through the skin for treatment of the skin during and / or following fractional laser radiation treatment of the skin are described.

The present invention relates to a system for quickly detecting tunnel deformation, comprising a rail walking mechanism (1) disposed on a subway rail, and an acquisition system (2) disposed on the rail walking mechanism (1); wherein the rail walking mechanism (1) is a T-shaped walking platform, comprising a cross shaft (11), a longitudinal shaft (12) and a stand column (13); the cross shaft (11) and the longitudinal shaft (12) are connected to form the T-shaped platform; tread wheels (16) are disposed at the bottom of the T-shaped platform; one end of the stand column (13) is vertically connected with the cross shaft (11), and the other end of the stand column is used for configuring an operating platform (14) of the acquisition system (2); the acquisition system (2) comprises a fractional laser structured light source (21), industrial focus-fixed cameras (22) and a computer; and the computer is connected with the industrial focus-fixed cameras (22). Compared with the prior art, the quick detection device can effectively solve the problem of detecting cross section deformation of tunnels, the problem of transforming many different local coordinate systems to a global coordinate system, and the problem of unstable test data caused by movements.

The invention is an all-optical Rb frequency standard method and system. The method: firstly, adjusting the pump laser to the wavelength corresponding to Rb D2 line; then modulating semiconductor laser by radio signal to produce optical component needed to excite coherent resonance, and using two proper side bands to excite Rb 0-0 ultrafine coherent resonant transition; when the frequency of fine crystal oscillator deviates, the atomic system outputs a deviation correcting signal to control VCO, to make the VCO return to original frequency. The system is composed of semiconductor laser diode, Rb atomic physical system, optical signal detecting and amplifying device and high-precision constant temperature VCO, which are linked with one another. It uses Rb atomic coherent resonant transition chart line to identify the frequency, and the frequency locking is higher; needs no mechanical exciting system, avoiding the effect of mechanical system; uses commercial fractional laser diode as excitation source.

A method of reducing scar formation associated with a skin wound includes providing an electromagnetic energy source, delivering energy from the electromagnetic energy source to opposing edges of a skin wound, and sealing the wound after delivering the energy. The electromagnetic energy source can include a laser, such as a fractional laser, including a fractional CO2 laser. Handpieces configured to reduce scar formation include one or more of a tissue eversion system, a medication delivery system, and a wound sealing system.

A method of reducing scar formation associated with a skin wound includes providing an electromagnetic energy source, delivering energy from the electromagnetic energy source to opposing edges of a skin wound, and sealing the wound after delivering the energy. The electromagnetic energy source can include a laser, such as a fractional laser, including a fractional CO2 laser. Handpieces configured to reduce scar formation include one or more of a tissue eversion system, a medication delivery system, and a wound sealing system.

The invention discloses an SF6 gas leakage detection method base on fractional laser-induced breakdown spectroscopy. The method employs a system which comprises an embedded system mainframe (18), a high-energy pulse laser (1), a beam expander (3), a focusing lens array (5), a beam splitter (6), a photoelectric detector array (10), a drive amplification output circuit (11), an acousto-optic tunable filter (12), an AOTF (acousto-optic tunable filter) drive controller (13) and a lens (19). Multiple points of a monitored area are subjected to LIBS (laser-induced breakdown spectroscopy) signal real-time analysis of elemental sulphur and elemental fluorine according to the fractional LIBS technology so as to judge whether SF6 gas is leaked or not and approximate concentration distribution of SF6 gas leakage. The SF6 gas leakage detection method base on fractional laser-induced breakdown spectroscopy has the advantages that fractional LIBS measurement is higher in efficiency than single-point measurement; the AOTF is adopted for two wavelength selections in LIBS analysis, a conventional spectrograph for beam splitting and spectral analysis is not needed, and accordingly analysis time is saved, and timeliness is improved; approximate concentration distribution of SF6 gas leakage can be analyzed while whether SF6 gas is leaked or not is judged.

The invention provides a treatment device (100) for fractional laser-based treatment. The treatment device comprises a treatment generator (80) comprising a treatment laser (20) and a laser scanning system (30). The laser scanning system comprises at least one movable deflection element and is configured and arranged for scanning laser light across an emission window (70) towards skin tissue (110) from a plurality of locations (74) in the emission window by moving the at least one deflection element relative to the emission window, whereby, in use, laser-based lesions (120) are generated inside the skin tissue. The treatment device also comprises a controller (60) for generating a predefined disposition of lesions (120) in the skin tissue by emitting laser light via selected ones of the plurality of locations in the emission window while the treatment device is moved relative to the skin surface (105). The controller is configured for generating an area disposition of the lesions by scanning the laser light across the emission window using the laser scanning system and deflecting laser light into the skin tissue via the plurality of locations while the treatment device is moved relative to the skin surface, whereas in the line treatment mode the controller is configured to generate a line disposition of the lesions inside the skin tissue from a single predefined location of the emission window by maintaining the at least one deflection element in a stationary position relative to the emission window while the treatment device is moved relative to the skin surface.

Disclosed is drug delivery system for effectively administering a drug into a human or animal body tissue. The microjet drug delivery system includes (a) a microjet injector including: a pressure chamber partially sealed by an elastic membrane and containing a pressure-inducing liquid fluid-tightly filled therein; and a drug chamber adjacent to the pressure chamber, wherein the elastic membrane is disposed between the pressure and drug chambers, wherein the drug solution is contained in the drug chamber, wherein the drug chamber has a micro-nozzle partially defined in a wall thereof for ejecting the drug solution out of the drug chamber; (b) a laser generator for generating a laser beam and emitting the laser beam out of the laser generator, wherein the laser generator is configured by irradiating the laser beam into the pressure-inducing liquid in the microjet injector, thereby generating a bubble in the pressure-inducing liquid; and (c) a fractional laser filter module configured for splitting the laser beam incident from the laser generator into a plurality of fractional laser beams, each beam has a reduced diameter, and for irradiating the fractional laser beams. According to the microjet drug delivery system, the pre-ablating of the skin with the fractional laser beams to partially remove the stratum corneum may enable the drug microjet based injection to allow the drug to be effectively invaded into a skin tissue at the portion where the stratum corneum is partially removed and relatively softened.

The invention relates to the technical field of medical instruments, in particular to an output laser positioning device for a fractional laser therapy system; the output laser positioning device for fractional laser therapy system comprises a mounting segment for mounting a lens at the tail end of a laser guide arm and a positioning segment for positioning output laser focal length of the laser guide arm, a body of the mounting segment is of tubular structure mating with the tail end of the laser guide arm, one end of the mounting segment is provided with a mounting part to be mounted to the tail end of the laser guide arm, the other end of the mounting segment is connected to the positioning segment, the mounting segment is also provided with a blow passage for blowing air to a mirror face of a laser head, and the positioning segment is provided with a suction passage. The output laser positioning device has the function that lens scurf at the tail end of the laser guide arm of the fractional laser therapy system can be efficiently cleared, and meanwhile harmful smoke generated in therapy can be integrally removed by suction.

A laser positioning machine tool comprises a drive device, a machine base, an X-Y-direction movement device arranged on the machine base, a workbench arranged on the X-Y-direction movement device, a Z-direction movement device connected with the side face of the workbench and the machine base, a cutter clamp arranged on the Z-direction movement device, a positioning base and a cooling device, wherein the positioning base and the cooling device are arranged on the workbench. The laser positioning machine tool further comprises a fractional laser positioning device and a processor, the drive device is a servo motor or a long-range hydraulic oil cylinder, the laser positioning machine tool further comprises a touch display screen connected to the processor and further comprises a protection cover, and the protection cover is buckled on the machine base. The machining efficiency and precision of the machine tool are high.

The invention relates to the technical field of fundamental research on burns and experimental animal models and provides a preparation method of a mouse skin burn model, comprising the specific step of preparing the mouse skin burn model by using exfoliative carbon dioxide fractional laser technology; burn wound area and depth can be precisely controlled during modeling, modeling time is short, a mouse is under slight anesthesia, and model making success rate and repetitive rate are high; the mouse skin burn model is expected to act as an important animal model in fundamental researches on burns.

The invention provides an output laser positioning device with an air suction channel. The output laser positioning device comprises a mounting section mounted at the tail end of a laser guiding arm,and a positioning section for positioning the focal length of an output laser of the laser guiding arm. The mounting section comprises a laser guiding arm mounting piece and a mounting section base. The mounting section is connected with the positioning section through the mounting section base. The positioning section is of a semi-tubular structure. The pipe wall of the positioning section is provided with the air suction channel. The free end of the positioning section is provided with a positioning ring. The output laser positioning device has the functions that exuvium of a lens at the tail end of the laser guiding arm of a fractional laser system is efficiently removed, and meanwhile, harmful smoke generated in therapy is sucked and removed in an integrated mode.

The invention relates to a skin treatment device (10) for fractional treatment of the skin (100) of a human being. A radiation source (5) emits a multi-mode laser beam (20) with a superposition (23) of mutually different higher-order laser modes. The multi-mode laser beam is configured by said superposition of different laser modes to simultaneously cause a first plurality of high-intensity zones, where the thermal threshold (TC) for collagen denaturation for the treatment zone (50) of the skin is at least reached, and a second plurality of low-intensity zones where the thermal threshold (TF) for fibroblast stimulation for the treatment zone of the skin is at least reached. This is advantageous for obtaining a skin treatment device with a simple and therefore low-cost fractional laser skin treatment system for combined collagen denaturation and fibroblast stimulation. The skin treatment device is based on non-uniform laser radiation in the form of the multi-mode laser beam.

The invention provides a fractional laser fog-absorption purification system device, which comprises a laser therapeutic instrument body, a support arm, a laser head, a blowing nozzle and an air pump;the support arm is arranged on the laser therapeutic instrument body, the laser head is arranged on the support arm and is connected with the laser therapeutic instrument body, and the blowing nozzleis arranged on the laser head; the air pump is arranged on the laser therapeutic instrument body; the air pump communicates with the blowing nozzle through an air blowing duct, the air pump is used for generating high-pressure air so that high-pressure airflow can be blown out in the laser emitting direction of the laser head through the blowing nozzle, and water mist generated in the working process of the laser head can be blown away. Therefore, in a laser scar removal treatment process, the influence of water mist generated by scar removal on the operation sight of a doctor can be effectively reduced, and meanwhile the situation that the scar removal effect of laser is influenced by the water mist can be avoided. The problem that the fractional laser fog-absorption purification systemdevice in the prior art cannot eliminate water fog generated in the treatment process, and consequently the treatment effect is affected is solved.

Fractional laser surgical equipment having multiple purposes including treatment of the vagina includes a laser controller in which a laser supply portion is formed at one end of a main body having a space therein and a laser emission hole is formed at the other end of the main body, and a laser irradiation portion formed to enable attachment to or detachment from the laser controller and having a pair of guide portions formed at a part making contact with the affected part such that the laser is irradiated between the guide portions. The fractional laser surgical equipment enables accurate laser targeting of the affected part, can prevent various side effects such as repetitive laser irradiation, can wash in advance and antibacterially treat insertion portions so as to be more sanitary since the insertion portions are attachable and detachable, and can reduce the time for operation preparation.

Disclosed is drug delivery system for effectively administering a drug into a human or animal body tissue. The microjet drug delivery system includes (a) a microjet injector including: a pressure chamber partially sealed by an elastic membrane and containing a pressure-inducing liquid fluid-tightly filled therein; and a drug chamber adjacent to the pressure chamber, wherein the elastic membrane is disposed between the pressure and drug chambers, wherein the drug solution is contained in the drug chamber, wherein the drug chamber has a micro-nozzle partially defined in a wall thereof for ejecting the drug solution out of the drug chamber; (b) a laser generator for generating a laser beam and emitting the laser beam out of the laser generator, wherein the laser generator is configured by irradiating the laser beam into the pressure-inducing liquid in the microjet injector, thereby generating a bubble in the pressure-inducing liquid; and (c) a fractional laser filter module configured for splitting the laser beam incident from the laser generator into a plurality of fractional laser beams, each beam has a reduced diameter, and for irradiating the fractional laser beams. According to the microjet drug delivery system, the pre-ablating of the skin with the fractional laser beams to partially remove the stratum corneum may enable the drug microjet based injection to allow the drug to be effectively invaded into a skin tissue at the portion where the stratum corneum is partially removed and relatively softened.

A treatment device for fractional laser-based skin treatment includes an emission window having an elongated area and predefined locations that are arranged in an elongated array which extends along a treatment axis of the window. A treatment generator has a treatment laser for emitting laser light towards skin tissue from the predefined locations in the emission window for generating, in use, laser-based lesions inside the skin tissue. The treatment device also includes a motion sensor for sensing motion of the treatment device relative to the skin surface, and a controller for determining a non-zero sequence of at least one of the predefined locations from which laser light is consecutively emitted in dependence on the sensed motion. The controller allows generation of the non-zero sequence when the sensed motion of the treatment device relative to the skin surface only has a component in a direction parallel to the treatment axis.

The present invention relates to fractional laser surgical equipment having multiple purposes including treatment of the vagina, which can treat various vaginal diseases by being inserted into the vagina of a woman and irradiate lasers at normal skin, and comprises: a laser controller in which a laser supply portion is formed at one end of a main body having a space therein and a laser emission hole is formed at the other end of the main body; and a laser irradiation portion formed to enable attachment to or detachment from the laser controller and having a pair of guide portions formed at a part making contact with the affected part such that the laser is irradiated between the guide portions. The fractional laser surgical equipment having multiple purposes including treatment of the vagina enables accurate laser targeting of the affected part, can prevent various side effects such as repetitive laser irradiation, can wash in advance and antibacterially treat a plurality of insertion portions so as to be more sanitary since the insert portions are attachable and detachable, and can reduce the time for operation preparation.

The invention provides a carbon dioxide fractional laser treatment instrument capable of arbitrarily deforming a treatment region, and belongs to the technical field of medical equipment. The carbon dioxide fractional laser treatment instrument comprises an output positioning cylinder, wherein a clamping joint and a positioning ring are arranged on the output positioning cylinder; a plurality of push rods are uniformly arranged, along circumference of a cross section of the output positioning cylinder, on the output positioning cylinder located between the clamping joint and the positioning ring; guide holes corresponding to the push rods one by one are formed in the output positioning cylinder; the push rods are slidably connected to the corresponding guide holes; outer ends of the push rods are connected with a driving mechanism capable of pushing the push rods to slide in the guide holes; a corrugated covering ring is arranged in the output positioning cylinder; the covering ring ismade of a soft heat-absorbing material; an outer side edge of the covering ring is fixedly connected with the output positioning cylinder; an inner side edge of the covering ring is connected with aninner end of each push rod; the covering ring is coaxial with the output positioning cylinder. The carbon dioxide fractional laser treatment instrument provided by the invention has advantages of emitting dot-matrix patterns of different shapes and the like.

The invention relates to a skin treatment device (10) for fractional treatment of the skin (100) of a human being. A radiation source (5) emits a multi-mode laser beam (20) with a superposition (23) of mutually different higher-order laser modes. The multi-mode laser beam is configured by said superposition of different laser modes to simultaneously cause a first plurality of high-intensity zones,where the thermal threshold (TC) for collagen denaturation for the treatment zone (50) of the skin is at least reached, and a second plurality of low-intensity zones where the thermal threshold (TF)for fibroblast stimulation for the treatment zone of the skin is at least reached. This is advantageous for obtaining a skin treatment device with a simple and therefore low-cost fractional laser skintreatment system for combined collagen denaturation and fibroblast stimulation. The skin treatment device is based on non-uniform laser radiation in the form of the multi-mode laser beam.

The present invention relates to a system for quickly detecting tunnel deformation, comprising a rail walking mechanism (1) disposed on a subway rail, and an acquisition system (2) disposed on the rail walking mechanism (1); wherein the rail walking mechanism (1) is a T-shaped walking platform, comprising a cross shaft (11), a longitudinal shaft (12) and a stand column (13); the cross shaft (11) and the longitudinal shaft (12) are connected to form the T-shaped platform; tread wheels (16) are disposed at the bottom of the T-shaped platform; one end of the stand column (13) is vertically connected with the cross shaft (11), and the other end of the stand column is used for configuring an operating platform (14) of the acquisition system (2); the acquisition system (2) comprises a fractional laser structured light source (21), industrial focus-fixed cameras (22) and a computer; and the computer is connected with the industrial focus-fixed cameras (22). Compared with the prior art, the quick detection device can effectively solve the problem of detecting cross section deformation of tunnels, the problem of transforming many different local coordinate systems to a global coordinate system, and the problem of unstable test data caused by movements.

The invention is an all-optical Rb frequency standard method and system. The method: firstly, adjusting the pump laser to the wavelength corresponding to Rb D2 line; then modulating semiconductor laser by radio signal to produce optical component needed to excite coherent resonance, and using two proper side bands to excite Rb 0-0 ultrafine coherent resonant transition; when the frequency of fine crystal oscillator deviates, the atomic system outputs a deviation correcting signal to control VCO, to make the VCO return to original frequency. The system is composed of semiconductor laser diode, Rb atomic physical system, optical signal detecting and amplifying device and high-precision constant temperature VCO, which are linked with one another. It uses Rb atomic coherent resonant transition chart line to identify the frequency, and the frequency locking is higher; needs no mechanical exciting system, avoiding the effect of mechanical system; uses commercial fractional laser diode as excitation source.

The invention provides a treatment device (100) for fractional laser-based skin treatment. The treatment device comprises an emission window (70) comprising an elongated area (75) and a plurality of predefined locations (74) in said elongated area (75), wherein the predefined locations (74) are arranged in an elongated array which extends along a treatment axis (72) of the window (70), and wherein each predefined location (74) in the array is located at a distance from the treatment axis (72), seen in a direction perpendicular to the treatment axis (72), which is smaller than 25% of a maximum distance between two predefined locations (74) in the array, seen in a direction parallel to the treatment axis (72). The treatment device further comprises a treatment generator (80) comprising a treatment laser (20) for emitting laser light (21) towards skin tissue (110) from said plurality of predefined locations (74) in the emission window (70) for generating, in use, laser-based lesions (120) inside the skin tissue (110). The treatment device further comprises a motion sensor (90) for sensing motion of the treatment device relative to the skin surface (105) and a controller (60) for determining a non-zero sequence of at least one of the plurality of predefined locations in the emission window from which laser light is consecutively emitted in dependence on the sensed motion. The controller is configured to activate the treatment generator to generate said non-zero sequence when the sensed motion of the treatment device relative to the skin surface only has a component in a direction parallel to the treatment axis.

The present invention belongs to the technical field of atomic emission spectroscopy, and relates to a weak optical source Rowland grating linear array CCD / CMOS detector optical splitting system and method, which is applied to a micron-sized fractional laser-induced breakdown spectroscopy great than or equal to 5 [mu]m. The optical splitting system successively comprises a plano-convex lens (2), afirst cylindrical lens (3), an entrance slit (4), a concave grating (5), a second cylindrical lens (6) and a CCD / CMOS detector (7) along a beam propagation direction. The entrance slit (4), the concave grating (5) and the CCD / CMOS detector (7) are on a Rowland circle, an optical source (1), the plano-convex lens (2) and the first cylindrical lens (3) are outside the Rowland circle, and are collinear with the entrance slit (4) and the concave grating (5). Compared with a conventional Rowland optical system, the optical splitting system has characteristics of being high in optical resolution, large in signal magnification times, great in signal-to-noise ratio and the like, and is especially suitable for spectral analysis of a monopulse and a plurality of pulses of a fractional laser spectrometer.

The present invention relates to a pharmaceutical composition for treating scars on the skin, comprising a mixture of botulinum toxin and air. The mixture of botulinum toxin and air according to the present invention, when injected in the dermis, may temporarily suppress the elasticity of the dermis and flatten out the depressed part of the scar, and thus enables elaborate intradermic resection and increases the effects of lasers for treating blood vessels or of fractional lasers. Thus, scars on the skin can be effectively improved through a one-time operation without negatively affecting the daily lives of patients.

The invention discloses a CO2 fractional laser sterilization experimental method. The method includes: conducting aseptic operation on a first strain and a second strain, and inoculating the strains into a solid medium to conduct culture; extracting single bacterial colony of each strain from the solid medium, performing inoculation into 5ml liquid media respectively, and placing the media into a 37DEG C constant temperature shaking table to conduct culture; taking 2.5ml of a culture liquid and adding it into a 10ml liquid medium, and performing culture in a 37DEG C constant temperature shaking table; by means of turbid comparison with a Mcfarland turbidimetric tube, preparing the bacterial liquids of the liquid media into bacterial liquids of three concentrations; coating culture dishes with each concentration bacterial liquid of every strain; irradiating the centers of the bacteria coated culture dishes by CO2 fractional laser, employing CO2 fractional laser with the irradiation energy intensity of 3J, 8J and 12J respectively to conduct irradiation for 1ms respectively on the culture dishes corresponding to three concentrations of each strain; placing the irradiated culture dish for each concentration bacterial liquid of every strain into a 37DEG C bacteria incubator to conduct culture; and after irradiation, observing whether bacterial colonies grow on the laser irradiated culture dishes continuously, if any, counting bacteria and representing the number by CFU (colony-forming units).