65 results about "Sweat gland" patented technology

The invention relates to the crossing field of biothermodynamics and dynamic environment control, and discloses a space thermal microclimate multi-target regulation and control method, device and system, a medium and a product. The method comprises the following steps: acquiring physiological parameters (including effective dressing thermal resistance and local sweat gland density of posture correction) of a passenger, environment space-time parameters and light environment parameters through a biological characteristic sensor, an environment sensor and an optical sensor; constructing a dynamic human body thermal comfort model library, and adopting a feature coding-parameter decoding mechanism to match a target thermal comfort model; generating a hierarchical regulation strategy based on the difference between the local comfortable temperature and humidity interval and the real-time thermal environment sensing parameter; and the refrigerant circulation system, the fluid circulation system and the optical radiation system are cooperatively controlled to realize local microclimate regulation and control. According to the method, the problems of inaccurate thermal comfort modeling and low multi-system cooperation efficiency in a transient environment are solved, the energy efficiency ratio is improved, and the comfort of passengers in a cabin is remarkably improved.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and / or skin repositioning and / or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

The invention relates to the technical field of intelligent medical assistance, in particular to a skin disease treatment electrode positioning system based on potential distribution. The system comprises a potential gradient severe region identification module, a lesion minimum surrounding region identification module, a similar potential region grouping module, an optimal electrode position prediction module, an electric field distribution calculation module, a sweat gland dense region identification module, an optimal electrode placement point screening module, an enhanced feature generation module and a final electrode position determination module. By fusing multi-source information such as skin surface potential distribution, lesion geometric characteristics, tissue conductivity, historical treatment data and the like, systematic optimization is performed on electrode positioning in skin disease treatment, the effectiveness of electrode stimulation is maximized on the premise of ensuring the treatment safety, and the treatment efficiency is improved. An accurate electrode placement scheme is provided for treatment of different types of skin diseases, and the method is suitable for accurate determination of the electrode placement position in electrical stimulation treatment.

The invention provides a one-way moisture-conducting skin-like fabric and a preparation method thereof.The one-way moisture-conducting skin-like fabric comprises a hydrophilic silicon dioxide layer, a fabric layer and a hydrophobic silicon dioxide layer from the front face to the back face, and the hydrophobic silicon dioxide layer and the hydrophilic silicon dioxide layer form a gradient wettability structure in the thickness direction of the fabric; the gradient wettability structure simulates skin sweat glands to achieve one-way spontaneous transportation of liquid drops from the back face to the front face, and the liquid drops cannot permeate in the reverse direction. Fluorine-free hydrophobic treatment is performed on the fabric through sulfydryl-alkene click reaction, a hydrophilic nano pit structure is introduced into a porous area on the front surface of the fabric through gummed paper covering plasma treatment, a gradient wetting interface is formed, and directional sweat transportation without external force driving is realized.

The invention relates to the technical field of primary local hyperhidrosis, in particular to a biomarker for detecting primary local hyperhidrosis and application of the biomarker, and the biomarker comprises but is not limited to one or more of the ratio of Th17 cells to Treg cells, IL-17A, IL-6, ROR gamma t and FoxP3. According to the invention, a multi-dimensional detection system covering PFH core pathological links (immune disorder, hyperactivity of sympathetic nerves and hyperfunction of sweat gland) is constructed by integrating immune related markers such as Th17 / Treg cell ratio, IL-17A, IL-6, ROR [gamma] t, FoxP3 and the like and combining the concentrations of peripheral blood epinephrine (E) and noradrenaline (NE) and the gene expression levels of sweat gland tissues AQP5 and Cacna1c. And a potential molecular target is provided for developing a novel therapeutic strategy (such as specific blocking of an IL-17 signal channel or enhancement of a Treg function) of a targeted Th17 / Treg axis.

The application discloses an OCT fingerprint recognition method based on a three-dimensional convolutional neural network, which comprises the following steps: obtaining OCT three-dimensional fingerprint data of a reference fingerprint and a fingerprint to be detected, and the OCT three-dimensional fingerprint data of the reference fingerprint and the fingerprint to be detected respectively contain one sweat gland and one sweat gland; the OCT fingerprint recognition method based on the three-dimensional convolutional neural network takes the three-dimensional data with the sweat gland as the center as the input of the recognition model, compared with the traditional two-dimensional epidermal pore recognition method, not only the feature information of the plane dimension is contained, but also the depth dimension information is increased, the three-dimensional morphological characteristics such as the spiral structure of the sweat gland are completely presented, these multi-dimensional three-dimensional data can provide more detailed and unique biological feature identification, and the distinguishing degree and the accuracy of the fingerprint recognition are effectively improved; meanwhile, the method can keep stable recognition performance under harsh conditions based on the three-dimensional data with the sweat gland as the center, and then the fingerprint anti-counterfeiting capability is significantly improved, and the false fingerprint attack can be effectively resisted.

1. The present invention provides an antiperspirant active ingredient based on zinc 2+ cations for use in hygiene products. 2.1 Antiperspirant active ingredients in hygiene products are currently based on aluminum 3+ cations, which cannot be obtained in an environmentally friendly manner, nor can a health risk be ruled out. Therefore, an alternative was sought in numerous series of tests and found in zinc 2+ cations. 2.2 Solutions of zinc 2+ cations in alcoholic liquid are to be patented as the active ingredient. In particular, a solution of zinc(II) chloride in ethanol of any concentration, but also solutions of any concentration of zinc(II) salts with other non-basic anions (e.g., zinc(II) sulfate) in alcohols (ethanol or isopropanol), induce an effective constriction of the sweat glands and thus have an antiperspirant effect.

The invention provides a long-acting bromhidrosis-removing nano composition and a preparation method thereof, and relates to the field of traditional Chinese medicine preparations. The long-acting bromhidrosis removal nano composition capable of treating both symptoms and root causes is obtained by fusing the traditional Chinese medicine sweating syndrome treatment theory and the nano transdermal technology, fundamental regulation and control of the armpit microenvironment are achieved through the triple mechanism of eliminating evil and strengthening the body resistance, transdermal synergism and ecological balance, and the drug effect durability is improved; the in-vitro half-life period of active ingredients such as ellagic acid is prolonged; preferably, the particle size of the nano silicon dioxide can convey the active ingredients to an apocrine duct, so that the effect of removing the active ingredients such as bromhidrosis berberine and ellagic acid is improved; according to the long-acting bromhidrosis-removing nano composition, fractionated coconut oil is adopted to neutralize the bitter cold property of coptis chinensis or berberine, and the skin irritation index is reduced to 0.32 (the traditional preparation is greater than or equal to 1.05), so that the long-acting bromhidrosis-removing nano composition has excellent long-acting antibacterial and bromhidrosis-removing effects and is small in skin irritation.

The invention belongs to the technical field of medical instrument evaluation, and particularly relates to a device for simulating the sweating state of a human body and a wearable flexible instrument electrical safety evaluation method.A sweat gland simulation module is arranged on a human body model, and the sweat gland simulation module is provided with a sweating panel and a sweat discharge pipe; the sweat discharge pipes are distributed on the sweating panel, the simulated skin covers the outer side of the human body model, the sweating holes of the sweating area of the simulated skin are connected with the outlets of the sweat discharge pipes, and sweat simulation liquid is provided for the sweat discharge pipes through the sweating control module, so that sweating simulation can be realized. A heating device and a temperature sensor are further arranged in the simulated skin, the temperature, the sweating speed and the sweating amount of the simulated skin are controlled through a control module, the wearable flexible instrument is worn on the outer side of the human body model, and then the change characteristics of leakage current of the wearable flexible instrument under the conditions of different sweating amounts and sweating speeds can be evaluated; and the short-circuit overload risk of key components is avoided.

The invention relates to the field of biology, in particular to an in-vitro separation, culture and identification method of human primary sweat gland muscle epithelial cells. The invention aims to solve the problems in the background technology, and provides an in-vitro separation, culture and identification method of human primary sweat gland epithelial cells, which is characterized by comprising the following steps: acquiring a skin specimen, preserving at low temperature, cleaning, digesting, cleaning, digesting, irradiating and disinfecting, adhering an implant to the wall, separating and planting, abandoning a culture medium, and observing and photographing. The specific operation modes are as follows: (1) acquiring a skin specimen: acquiring the skin specimen through an operation; and (2) low-temperature preservation: putting into a sterile PBS (Phosphate Buffer Solution) containing double antibodies of 1 * penicillin (100U / ml)-streptomycin (0.1 g / ml) for low-temperature preservation. The method disclosed by the invention has the beneficial effects that sweat gland cells are cultured by utilizing a sweat gland tissue block adherent method, sweat gland muscle epithelial cells are obtained and separated by using pancreatin digestive juice at a time point when the cells grow for one week, and in addition, the cells are different in adherent capability.

This invention belongs to the field of mixing tank technology, and specifically relates to a vertical high-intensity mixing tank for convenient cleaning of adhesive materials. The technology includes a tank body, on which a pressurized water-permeable sweat gland liner is installed on the inner wall. A dissolving pool is located between the sweat gland liner and the tank body to diffuse the pressurized water, and a water supply mechanism is installed on the dissolving pool to supply pressurized water to its interior. In this design, a pressurized water-permeable sweat gland liner is installed on the inner wall of the original mixing tank. Adhesive materials adhere to the sweat gland liner. With the coordinated design of the dissolving pool, after pressurized water is added to the dissolving pool, the water in the dissolving pool seeps out from the sweat gland liner. At this time, a water film forms on the interface between the sweat gland liner and the adhesive material. The water film dissolves the adhesive material on the interface into a slurry. The adhesive layer loses its adhesion to the liner and, under the action of a scraper and gravity, detaches from the liner, thus removing the adhesive material from the tank wall.

The present disclosure relates, in part, to a method of treating acne, excessive sweating, unwanted hair, and / or unwanted blood vessels. The method can include providing a needle array comprising a plurality of needles; inserting the plurality of needles into a dermis of a treatment area; detecting a location of an enlarged sebaceous gland; and exciting one or more of the plurality of needles to treat the sebaceous gland, one or more sweat glands, a vascular lesion, an unwanted hair follicle, and / or an unwanted blood vessel.

The utility model discloses an active breathable heating mattress, which belongs to the technical field of bedding articles, and comprises a mattress small edge and a mattress support body, an inner cavity is formed between the mattress small edge and the mattress support body, and a functional cushion layer is arranged in the inner cavity; the functional cushion layer comprises a functional cushion base, a flow guide fan and an air guide pipe, the flow guide fan and the air guide pipe are arranged on the functional cushion base, the air guide pipe is communicated with an air outlet of the flow guide fan, and the air outlet of the flow guide fan is further provided with a heating module; a fan window is formed in the side edge of the mattress small edge, and the air opening end of the flow guide fan faces the fan window. The active breathable heating mattress solves the problem that when an existing mattress is heated, sweat gland perspiration can be promoted, so that the humidity is increased, and the body feeling of a user is reduced.

Provided herein are methods and compositions for identifying ionocytes from respiratory epithelial cells, and uses of such cells for treatment of inflammatory lung disease. Also provided herein are methods and compositions for modulating respiratory tract epithelial cell proliferation, differentiation, maintenance, and / or function.

The embodiment of the invention provides a natural light supplementing method, system and device, electronic equipment and a storage medium, and the method comprises the steps: collecting the pupil diameter and the facial activated sweat gland density of a user, and determining the pupil diameter change rate according to the pupil diameter; determining a motor rotation angle of a motor for the curtain according to the pupil diameter change rate and the face activated sweat gland density; controlling the motor to drive the curtain to rotate according to the motor rotation angle. Through the embodiment of the invention, the curtain can be automatically controlled based on the change of the pupil diameter of the user and the current facial activated sweat gland density, so that the curtain is automatically controlled based on the current state of the user, and automatic light supplement to different degrees in a room is realized.

The invention relates to the technical field of medicine preparation, in particular to application of a serine protease inhibitor in preparation of medicine for treating hyperhidrosis, animal experiments prove that the serine protease inhibitor can inhibit sweat gland cell activity, new use of old medicine is achieved, sweat gland secretion is improved, and the effect of treating hyperhidrosis is achieved. And a new scheme is provided for development of drugs for treating the polyhamia.

The invention belongs to the technical field of medical dressings, and relates to a DNA hydrogel dressing with a skin-like structure and function as well as a preparation method and application of the DNA hydrogel dressing. The dressing is structurally characterized in that a skin-like three-layer structure, namely an epidermal layer, a corium layer and a subcutaneous tissue layer, is constructed by regulating and controlling the cross-linking degree of chain segments and combining a directional freezing technology, and an extracellular matrix microenvironment is provided for physiological activities of cells. In function, an aptamer sequence with a specific function is introduced, and stem cells are induced to directionally differentiate into cells required by tissue repair; the subcutaneous tissue-like layer is loaded with resveratrol, and fascia is activated to induce regeneration of skin appendages; in view of the fact that chronic ulcerative wounds are easily attacked by bacteria, the antibacterial peptide and a functional DNA sequence of targeted bacteria form an antibacterial peptide-DNA composite chain segment through a click reaction, and the dressing is endowed with targeted antibacterial performance. The prepared dressing has a skin-imitating three-dimensional structure and performance, can guide skin appendages such as regeneration of hair follicles and sweat glands, and can be widely applied to repair treatment of chronic wounds.

A method for detecting finger forgery attacks based on OCT volume data, comprising: detecting the number of minutiae of internal and external fingerprints and the number of subcutaneous sweat glands; setting the minutiae number thresholds num1, num2, the sweat gland number threshold num3, the internal and external fingerprint matching score threshold t, and the coincidence rate n between the position of subcutaneous sweat glands and the internal fingerprint ridge lines; if the number of internal fingerprint minutiae is more than num1 and the number of external fingerprint minutiae is more than num2, then calculate the internal and external fingerprint matching score; if the number of internal fingerprint minutiae is less than num1, directly determine it as a finger forgery attack; if the number of sweat glands is less than num3, directly determine it as a finger forgery attack; if the number of sweat glands is more than num3, if the internal and external fingerprint matching score is higher than t, the system directly passes the detection; if the number of sweat glands is less than num3 and at the same time the number of internal fingerprint minutiae is less than num1, enter the next step; calculate the coincidence rate between the position of subcutaneous sweat glands and the internal fingerprint ridge lines; if the coincidence rate is higher than the set value n, pass the detection, otherwise determine it as a finger forgery attack.

The invention provides a human skin sweat gland three-dimensional shape obtaining method and system and electronic equipment, and relates to the technical field of optical coherence tomography and medical image segmentation, and the method comprises the steps: obtaining an initial to-be-detected region skin OCT image through a spectral domain optical coherence tomography system; preprocessing the skin OCT image of the initial to-be-detected area, wherein preprocessing comprises but is not limited to one or more of cutting, overturning, size adjustment and contrast adjustment; inputting the preprocessed skin OCT image of the initial to-be-detected area into a three-dimensional segmented skin sweat gland network model trained in advance based on deep learning, and performing three-dimensional segmentation on the preprocessed skin OCT image of the initial to-be-detected area by the deep learning model to obtain a three-dimensional segmentation result of sweat glands; according to the three-dimensional shape obtaining method, the three-dimensional shape information of the sweat gland of the human skin can be obtained in a real-time and non-invasive mode, the two-dimensional, in-vitro and destructive limitation of a traditional skin biopsy technology is overcome, and the accuracy and efficiency of sweat gland shape analysis are remarkably improved.

This invention relates to the field of signal processing technology, providing a method, device, and storage medium for physiological state analysis based on skin sweat glands and electromagnetic waves. The method includes: simultaneously acquiring electrical signals from a user's skin sweat glands and conductive signals from electromagnetic waves; extracting features from both the skin sweat gland electrical signals and the electromagnetic wave conductive signals; inputting the extracted features into a pre-trained time synchronization and causal correlation model, establishing a dynamic mapping relationship between the skin sweat gland electrical signal features and the electromagnetic wave conductive signal features within the time synchronization and causal correlation model, and performing feature fusion based on this dynamic mapping relationship; and generating a classification result of the user's physiological state based on the output of the time synchronization and causal correlation model. By using a time synchronization and causal correlation model for skin sweat gland electrical signals and electromagnetic wave conductive signals to collaboratively analyze the two signals, the aim is to improve the accuracy and robustness of physiological state monitoring.

The present invention relates to the field of polymer application, in particular to a polypeptide compound and the use thereof in the field of cosmetics. Disclosed in the present invention is a low-molecular-weight polypeptide compound with a structural formula of [γ-glu]n-Aa, wherein n is 1-10, glu is glutamic acid, and Aa is selected from any one of glycine, alanine, valine, leucine, isoleucine, phenylalanine, tryptophan, tyrosine, aspartic acid, asparagine, glutamic acid, lysine, glutamine, methionine, serine, threonine, cysteine, proline, histidine or arginine. In the structural formula, n is preferably 1-8. The polypeptide derivative has a molecular weight of 250-1500 Da. Tests show that the above-described polypeptide compound has an excellent moisturizing performance and a low molecular weight, which is beneficial for absorption and utilization by the skin, thereby reducing the risk of clogging pores and sweat gland openings.

The invention discloses an OCT fingerprint identification method based on a three-dimensional convolutional neural network, and the method comprises the steps: obtaining the OCT three-dimensional fingerprint data of a reference fingerprint and a to-be-detected fingerprint, and enabling the OCT three-dimensional fingerprint data of the reference fingerprint and the to-be-detected fingerprint to respectively comprise a sweat gland and a sweat gland; according to the OCT fingerprint identification method based on the three-dimensional convolutional neural network, the three-dimensional data with the sweat gland as the center is used as the input of the identification model, compared with a traditional two-dimensional epidermal sweat pore identification method, feature information of a plane dimension is included, depth dimension information is increased, three-dimensional morphological features such as a spiral structure of the sweat gland are completely presented, and the identification accuracy of the OCT fingerprint identification method based on the three-dimensional convolutional neural network is improved. The multi-dimensional three-dimensional data can provide finer and more unique biological feature identification, and the discrimination and accuracy of fingerprint identification are effectively improved. Meanwhile, according to the method, identification is carried out based on three-dimensional data with sweat glands as the center, stable identification performance can be kept under severe conditions, the fingerprint anti-counterfeiting capability is further remarkably improved, and false fingerprint attacks are effectively resisted.

The invention relates to a foot washing liquid for foot care and a care method, and relates to the technical field of herbaceous plant lotions, the lotion takes the synergistic effect of sweat inhibition and source control and astringency repair as the core, regulates sweat gland secretion, and radically inhibits the fungal breeding environment; meanwhile, aiming at the pathological difference between erosive tinea pedis and keratotic tinea pedis, compounds are converged, and healing of ulcerative wounds and softening of chapped cutin are accelerated. Herbaceous plant component extracts are fused with chemical effective components, and various skin care essences are added, so that the risk of skin irritation is avoided; and a simple preparation process is combined, so that the production cost is remarkably reduced. According to the scheme, the limitation of single sterilization of a traditional lotion is broken through, collaborative treatment from disease source inhibition to symptom elimination is realized, the healing efficiency is effectively improved, the recurrence rate is greatly reduced, and a safe and universal radical treatment means is provided for patients with different types of tinea pedis.

The present invention relates to the field of polymer application, in particular to a polypeptide compound and the use thereof in the field of cosmetics. Disclosed in the present invention is a low-molecular-weight polypeptide compound with a structural formula of [γ-glu]n-Aa, wherein n is 1-10, glu is glutamic acid, and Aa is selected from any one of glycine, alanine, valine, leucine, isoleucine, phenylalanine, tryptophan, tyrosine, aspartic acid, asparagine, glutamic acid, lysine, glutamine, methionine, serine, threonine, cysteine, proline, histidine or arginine. In the structural formula, n is preferably 1-8. The polypeptide derivative has a molecular weight of 250-1500 Da. Tests show that the above-described polypeptide compound has an excellent moisturizing performance and a low molecular weight, which is beneficial for absorption and utilization by the skin, thereby reducing the risk of clogging pores and sweat gland openings.

Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.

The invention provides a biological microsphere and a preparation method thereof, and a multi-skin appendage in-situ regeneration method, the biological microsphere is constructed by loading a small molecule compound combination and a protein by using a lipid carrier sphere, the small molecule compound combination and the protein are integrated, and the lipid carrier sphere is used for slow release, so that epigenetics can be deeply changed; the method has the advantages of maintaining cell proliferation, activating hair papilla cell and sweat gland cell fate, greatly promoting the cell fate conversion efficiency, achieving cell reprogramming, being safe, efficient and easy to operate, and avoiding the safety risk of gene editing, thereby effectively solving the problems of wound repairing, scar weakening and skin functional regeneration.

This invention discloses a method for planning minimally invasive axillary treatment based on thermal imaging, belonging to the field of medical image processing technology. The method includes: acquiring and preprocessing infrared thermal imaging data of the patient's axillary region to generate a thermal imaging sequence; calculating the temperature change amplitude, temperature rise rate, and local temperature gradient of each pixel based on the thermal imaging sequence to generate a set of sweat gland activity features; inputting the sweat gland activity feature set into a pre-established sweat gland activity prediction model to obtain the sweat gland activity distribution results within a future preset time window; using the sweat gland activity distribution results as the optimization target, and combining axillary risk tissue constraints, optimizing the path position, insertion angle, and depth of action of the minimally invasive needle path to generate the optimal minimally invasive needle path. This invention improves the positioning accuracy and treatment consistency of minimally invasive axillary treatment by constructing a sweat gland activity prediction mechanism based on thermal imaging sequences and linking it with minimally invasive needle path constraint optimization.

The invention discloses a multi-mode directional perspiration sensor and a preparation method thereof, and belongs to the technical field of sensors. The electrophysiological electrode, the hydrophobic layer, the hydrophilic layer and the electrochemical electrode are arranged in sequence, the control circuit is arranged on the hydrophilic layer to collect signals, during use, the electrophysiological electrode and the hydrophobic layer are attached to the skin, sweat is discharged to a contact interface of the skin and the sensor through sweat glands, and the sensor is used for detecting the sweat glands. Sweat is directionally conveyed to the upper surfaces of the electrochemical electrode and the control circuit from the contact interface of the skin and the sensor, so that on one hand, the interference of the sweat on electrophysiological signal acquisition can be reduced, and the electrophysiological signal is enhanced; on the other hand, sweat is gathered on the upper surface of the sensor, so that electrochemical signal acquisition is facilitated, and meanwhile, the sensor has relatively good air permeability and wearing comfort.

The utility model relates to the technical field of minimally invasive excision of armpit apocrine gland, in particular to an electric cutting device for minimally invasive excision of armpit apocrine gland, which comprises a hollow shell, one end of the shell is provided with a cutting head, the other end of the shell is connected with a negative pressure device, the cutting head is provided with a cutting window, and the negative pressure device is connected with the cutting window. A fixed cutting head is arranged on the cutting window, a driving mechanism is arranged on the shell, a driving shaft is arranged in the shell, one end of the driving shaft is connected with the output end of the driving mechanism, a movable cutting head is arranged at the other end of the driving shaft, and the movable cutting head and the fixed cutting head are arranged correspondingly. The driving mechanism is used for controlling the movable cutting head to do linear reciprocating motion parallel to the fixed cutting head through the driving shaft, so that the movable cutting head and the fixed cutting head cut the apocrine gland tissue at the cutting window, and the negative pressure device is used for extracting the cut apocrine gland tissue from the shell. The apocrine gland cutting device can cut apocrine gland tissues more cleanly, and relapse is avoided.