15 results about "Sweat gland" patented technology

The invention relates to the technical field of intelligent medical assistance, in particular to a skin disease treatment electrode positioning system based on potential distribution. The system comprises a potential gradient severe region identification module, a lesion minimum surrounding region identification module, a similar potential region grouping module, an optimal electrode position prediction module, an electric field distribution calculation module, a sweat gland dense region identification module, an optimal electrode placement point screening module, an enhanced feature generation module and a final electrode position determination module. By fusing multi-source information such as skin surface potential distribution, lesion geometric characteristics, tissue conductivity, historical treatment data and the like, systematic optimization is performed on electrode positioning in skin disease treatment, the effectiveness of electrode stimulation is maximized on the premise of ensuring the treatment safety, and the treatment efficiency is improved. An accurate electrode placement scheme is provided for treatment of different types of skin diseases, and the method is suitable for accurate determination of the electrode placement position in electrical stimulation treatment.

The application discloses an OCT fingerprint recognition method based on a three-dimensional convolutional neural network, which comprises the following steps: obtaining OCT three-dimensional fingerprint data of a reference fingerprint and a fingerprint to be detected, and the OCT three-dimensional fingerprint data of the reference fingerprint and the fingerprint to be detected respectively contain one sweat gland and one sweat gland; the OCT fingerprint recognition method based on the three-dimensional convolutional neural network takes the three-dimensional data with the sweat gland as the center as the input of the recognition model, compared with the traditional two-dimensional epidermal pore recognition method, not only the feature information of the plane dimension is contained, but also the depth dimension information is increased, the three-dimensional morphological characteristics such as the spiral structure of the sweat gland are completely presented, these multi-dimensional three-dimensional data can provide more detailed and unique biological feature identification, and the distinguishing degree and the accuracy of the fingerprint recognition are effectively improved; meanwhile, the method can keep stable recognition performance under harsh conditions based on the three-dimensional data with the sweat gland as the center, and then the fingerprint anti-counterfeiting capability is significantly improved, and the false fingerprint attack can be effectively resisted.

This invention belongs to the field of mixing tank technology, and specifically relates to a vertical high-intensity mixing tank for convenient cleaning of adhesive materials. The technology includes a tank body, on which a pressurized water-permeable sweat gland liner is installed on the inner wall. A dissolving pool is located between the sweat gland liner and the tank body to diffuse the pressurized water, and a water supply mechanism is installed on the dissolving pool to supply pressurized water to its interior. In this design, a pressurized water-permeable sweat gland liner is installed on the inner wall of the original mixing tank. Adhesive materials adhere to the sweat gland liner. With the coordinated design of the dissolving pool, after pressurized water is added to the dissolving pool, the water in the dissolving pool seeps out from the sweat gland liner. At this time, a water film forms on the interface between the sweat gland liner and the adhesive material. The water film dissolves the adhesive material on the interface into a slurry. The adhesive layer loses its adhesion to the liner and, under the action of a scraper and gravity, detaches from the liner, thus removing the adhesive material from the tank wall.

The invention belongs to the technical field of medical dressings, and relates to a DNA hydrogel dressing with a skin-like structure and function as well as a preparation method and application of the DNA hydrogel dressing. The dressing is structurally characterized in that a skin-like three-layer structure, namely an epidermal layer, a corium layer and a subcutaneous tissue layer, is constructed by regulating and controlling the cross-linking degree of chain segments and combining a directional freezing technology, and an extracellular matrix microenvironment is provided for physiological activities of cells. In function, an aptamer sequence with a specific function is introduced, and stem cells are induced to directionally differentiate into cells required by tissue repair; the subcutaneous tissue-like layer is loaded with resveratrol, and fascia is activated to induce regeneration of skin appendages; in view of the fact that chronic ulcerative wounds are easily attacked by bacteria, the antibacterial peptide and a functional DNA sequence of targeted bacteria form an antibacterial peptide-DNA composite chain segment through a click reaction, and the dressing is endowed with targeted antibacterial performance. The prepared dressing has a skin-imitating three-dimensional structure and performance, can guide skin appendages such as regeneration of hair follicles and sweat glands, and can be widely applied to repair treatment of chronic wounds.

This invention relates to the field of signal processing technology, providing a method, device, and storage medium for physiological state analysis based on skin sweat glands and electromagnetic waves. The method includes: simultaneously acquiring electrical signals from a user's skin sweat glands and conductive signals from electromagnetic waves; extracting features from both the skin sweat gland electrical signals and the electromagnetic wave conductive signals; inputting the extracted features into a pre-trained time synchronization and causal correlation model, establishing a dynamic mapping relationship between the skin sweat gland electrical signal features and the electromagnetic wave conductive signal features within the time synchronization and causal correlation model, and performing feature fusion based on this dynamic mapping relationship; and generating a classification result of the user's physiological state based on the output of the time synchronization and causal correlation model. By using a time synchronization and causal correlation model for skin sweat gland electrical signals and electromagnetic wave conductive signals to collaboratively analyze the two signals, the aim is to improve the accuracy and robustness of physiological state monitoring.

Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.

This invention discloses a method for planning minimally invasive axillary treatment based on thermal imaging, belonging to the field of medical image processing technology. The method includes: acquiring and preprocessing infrared thermal imaging data of the patient's axillary region to generate a thermal imaging sequence; calculating the temperature change amplitude, temperature rise rate, and local temperature gradient of each pixel based on the thermal imaging sequence to generate a set of sweat gland activity features; inputting the sweat gland activity feature set into a pre-established sweat gland activity prediction model to obtain the sweat gland activity distribution results within a future preset time window; using the sweat gland activity distribution results as the optimization target, and combining axillary risk tissue constraints, optimizing the path position, insertion angle, and depth of action of the minimally invasive needle path to generate the optimal minimally invasive needle path. This invention improves the positioning accuracy and treatment consistency of minimally invasive axillary treatment by constructing a sweat gland activity prediction mechanism based on thermal imaging sequences and linking it with minimally invasive needle path constraint optimization.

The invention discloses a multi-mode directional perspiration sensor and a preparation method thereof, and belongs to the technical field of sensors. The electrophysiological electrode, the hydrophobic layer, the hydrophilic layer and the electrochemical electrode are arranged in sequence, the control circuit is arranged on the hydrophilic layer to collect signals, during use, the electrophysiological electrode and the hydrophobic layer are attached to the skin, sweat is discharged to a contact interface of the skin and the sensor through sweat glands, and the sensor is used for detecting the sweat glands. Sweat is directionally conveyed to the upper surfaces of the electrochemical electrode and the control circuit from the contact interface of the skin and the sensor, so that on one hand, the interference of the sweat on electrophysiological signal acquisition can be reduced, and the electrophysiological signal is enhanced; on the other hand, sweat is gathered on the upper surface of the sensor, so that electrochemical signal acquisition is facilitated, and meanwhile, the sensor has relatively good air permeability and wearing comfort.

The utility model relates to the technical field of minimally invasive excision of armpit apocrine gland, in particular to an electric cutting device for minimally invasive excision of armpit apocrine gland, which comprises a hollow shell, one end of the shell is provided with a cutting head, the other end of the shell is connected with a negative pressure device, the cutting head is provided with a cutting window, and the negative pressure device is connected with the cutting window. A fixed cutting head is arranged on the cutting window, a driving mechanism is arranged on the shell, a driving shaft is arranged in the shell, one end of the driving shaft is connected with the output end of the driving mechanism, a movable cutting head is arranged at the other end of the driving shaft, and the movable cutting head and the fixed cutting head are arranged correspondingly. The driving mechanism is used for controlling the movable cutting head to do linear reciprocating motion parallel to the fixed cutting head through the driving shaft, so that the movable cutting head and the fixed cutting head cut the apocrine gland tissue at the cutting window, and the negative pressure device is used for extracting the cut apocrine gland tissue from the shell. The apocrine gland cutting device can cut apocrine gland tissues more cleanly, and relapse is avoided.

The invention provides a targeted antiperspirant, and relates to the technical field of targeted antiperspirants. The preparation method of the targeted antiperspirant specifically comprises the following steps: (1) preparing a chelating protective agent; (2) preparing an aluminum chlorohydrate activating solution; (3) preparing blank micelles; (4) micelle loading; (5) cooling and curing; and (6) emulsification preparation. According to the technology, the self-assembly characteristic of poloxamer 407 is utilized, micelles with the particle size of about 20nm are formed through self-assembly, the micelles are disintegrated at the skin temperature and release aluminum chlorohydrate nanogel clusters through nucleation and efficient entrapment of aluminum chlorohydrate hydrolysis intermediates, the micelles are crosslinked into a porous physical membrane after encountering sweat, sweat gland ducts are reversibly blocked, and the effect of inhibiting the sweat gland ducts is achieved. According to the present invention, with the application of the bisabolol, the sweat can be prevented from being smoothly discharged to the skin surface so as to achieve the efficient sweat stopping effect, the inulin and the antibacterial component are added to maintain the balance of the armpit flora, the sweat stopping and the deodorization are combined, and the bisabolol can be efficiently fused so as to relieve the skin and strengthen the skin barrier during the nursing.

The application discloses a method for culturing sweat gland cells to obtain a sweat gland organoid and application thereof, and belongs to the technical field of bioengineering, wherein the sweat gland cells can be cultured by using a three-dimensional culture medium provided by the application, and a sweat gland organoid with high cell activity and bidirectional differentiation potential is obtained; after being transplanted into a full-thickness injury mouse on the sole and back, the sweat gland organoid not only can promote the regeneration and function recovery of the sweat gland, but also can promote the healing of the skin wound, and can be used for preparing a cell product for repairing skin injury and recovering the function of an accessory organ, and has a wide application prospect.

The invention provides a skin grafting device which comprises a skin taking structure and a driving part, the skin taking structure comprises a plurality of skin taking parts, each skin taking part comprises a tool bit and a first connecting part, the first connecting parts extend in the first direction, and the tool bits are connected to the ends, in the first direction, of the first connecting parts; the other end, in the first direction, of the first connecting part is rotatably connected to the driving part, the multiple skin taking parts are arranged at intervals in the direction perpendicular to the first direction, and the driving part is used for driving the skin taking parts to rotate around the axis parallel to the first direction. The multiple skin taking parts take skin at the same time, the skin taking efficiency is remarkably improved, in the rotation process of the skin taking parts, the tool bit extracts skin tissue, tiny autologous skin extracted by the skin taking parts carries hair follicles, sweat glands, melanocytes and the like, and the multiple skin taking parts carry the autologous skin to be implanted into allogeneic skin or artificial skin at the same time, so that a complete skin function reconstruction basis is provided, and the skin taking efficiency is improved. Therefore, the skin transplantation effect and the skin transplantation efficiency are improved, and meanwhile, a smaller wound is generated on a skin tissue donor region.

The application discloses a detection technology field of human sweat, and particularly relates to an electric field input method of a sweat promoting device for human wearing, which comprises the following operation steps: S1: two low-voltage pulses are generated to rapidly form electrically induced pores on the surface of the skin, wherein the first pulse voltage is 2-10 V, the pulse time is 300-600 ms, then, on the basis of the pulse, a second pulse voltage of 15-35 V is output, the pulse time is 10-30 ms, and the pulse is an exponential decay type pulse; S2: the first pulse voltage is obviously lower than the second pulse voltage, after starting to work, the circuit outputs a certain voltage, the size of the skin resistance is analyzed according to the formed current, and the first pulse voltage and the second pulse voltage are adjusted according to the skin resistance, the method is safe and fast, can generate temporary permeable pores in a short time, thereby rapidly improving the permeability of sweat promoting drugs, accelerating the speed of sweat gland perspiration, and greatly improving the experience of users during use.

A non-invasive technique for enhancing the delivery of botulinum toxins through the skin, utilizing low-frequency ultrasound as a pretreatment, is provided. The ultrasound- facilitated transdermal delivery approach provides an efficient, comfortable and needle-free alternative to conventional injection-based administration of botulinum toxins, and is applicable to a wide range of therapeutic and cosmetic uses, including, reducing or modulating sweat gland activity, relaxing or inhibiting muscle activity, alleviating pain, minimizing wrinkles or fine lines, and treating or preventing pathologies such as neuromuscular and neurological disorders, glandular dysfunction, urological conditions, ophthalmological disorders, gastrointestinal conditions and / or respiratory disorders