92 results about "Skin function" patented technology

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and/or skin repositioning and/or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

The invention relates to a preparation method of tissue engineering skin containing appendant organs. In the invention, the preparation method comprises the following steps of: inoculating amniotic mesenchyme stem cells, amniotic mesenchyme stem cells induced to the directions of hair papillae, amniotic epithelial cells and amniotic epithelial cells induced to the directions of the epithelia of the sweat gland into a gel solution, then inoculating the amniotic epithelial cells and the amniotic epithelial cells induced by keratinocyte in a warp direction on the surface of a structure of the hair follicle and the sweat gland after culturing by a dermal layer by induced culture forming the structure of the hair follicle and the sweat gland, and obtaining the tissue engineering skin with the structure of the hair follicle and the sweat gland after culturing. The skin has elasticity, toughness, vigorous cellular metabolism, strong multiplication capacity, sufficient secretion of extracellular matrices, tight linkage of the cuticular layer, the inophragma and the cells of the dermal layer and little possibility of falling off, enhances the success rate of transplantation, can promote the healing of a wound surface, enhances the effects of restoration and replacement and has the function of regulating the immunological rejection of a receptor; by the contained structure of the hair follicle and the sweat gland, the function of the skin is more complete; the adopted amniotic tissues are postpartum wastes and have extensive source, strong cell multiplication capability and multiplepassage frequency; and the invention is beneficial to the mass production of seed cells and lowers the industrialization cost.

Disclosed is a non-natural ceramide compound effective for a sphingosine kinase activator, and thus useful for a skin disease treating agent. The sphingosine kinase activator enhances production of sphingosine-1-phosphate to show various physiological activities provided by sphingosine-1-phosphate. The physiological activities include the effects of: controlling multiplication and differentiation of keratinocytes, multiplication of fibroblasts and collagen synthesis, resulting in treatment of wounds, recovery of damaged skin functions in atopic dermatitis and psoriasis; inhibiting wrinkles and skin irritation caused by ultraviolet rays, followed by improvement of wrinkles and inhibition of skin aging; and reducing skin atrophy, which is a typical side effect of local application steroids. Therefore, the sphingosine kinase activator is useful for a skin disease treating agent for treating skin wounds, wrinkles, atopic dermatitis, eczema, psoriasis, or skin atrophy caused by side effects of local application steroids.

The invention provides a mild skin cream with a function of improving skin and a preparation method of the skin cream. The skin cream comprises at least one glucoside emulsifier, at least one grease and at least one active additive. With the adoption of the mild skin cream, a lamellar liquid crystal net structure close to a sebum system of human skin can be formed, so that a surface tension between a liquid crystal phase and an oil phase is very low, the strength of an interfacial film is strengthened, the liquid drop coalescence is prevented or delayed, the stability of an emulsifying system is improved, and the moisturizing effect is enhanced; and cetearyl glucoside is a natural raw material, so that the rheological property is good and the refreshing skin feeling is promoted.

The invention relates to a cosmetic composition in the technical field of daily chemical products, in particular to an anti-blue-light cosmetic composition and a preparation method thereof. The composition is mainly prepared from, by mass, 0.1-8 parts of a citrus extract, 0.1-4 parts of a lespedeza capitata leaf/stem extract, 0.1-4 parts of cerium oxide, 0.1-8 parts of a buddleja officinalis extract, 0.1-10 parts of a hedychium coronarium root extract and 0.1-8 parts of a rutin compound. The anti-blue-light cosmetic composition can brighten the skin, reduce the oxidative damage to the skin caused by blue light, increase the survival quantity of epidermal keratinocytes under the UV radiation, maintain the integrity of the skin function, reduce the chronic mild inflammation of light aging, and provide a skin protection effect by reducing free radicals produced by the induced oxidative stress, so that the generation amount of active oxygen ROS declines to improve local microcirculation and play a vasoconstriction role, thereby controlling the fatigue signs caused by direct blue light irradiation, keeping the skin in balance of circadian rhythms, and keeping the skin in a health status.

The invention discloses an antibacterial hydrogel skin dressing preparation method. The method is characterized by including steps: adding polyvinyl alcohol into deionized water to obtain polyvinyl alcohol solution, adding an antibacterial agent into the polyvinyl alcohol solution, and controlling the mass concentration of the antibacterial agent in the solution to be 0.5-8%; then, cooling the solution at the room temperature, adding sodium hyaluronate into the solution, and stirring at the room temperature to dissolve completely; finally, transferring the obtained into a plate, freezing, taking out, and placing at the room temperature to obtain hydrogel skin dressing with an antibacterial effect. The hydrogel skin dressing has high antibacterial activity on gram positive bacteria and gramnegative bacteria, pains and secondary injuries caused by replacement of common dressing can be alleviated for patients, wound healing is promoted while pain alleviation is realized, scars are reduced, and a remarkable effect on skin function recovery is achieved.

The invention discloses a nanometer cross-linked sodium hyaluronate gel, a preparation method and applications thereof, wherein the particle size of the nanometer cross-linked sodium hyaluronate gel is 100-500 nm. According to the present invention, the nanometer cross-linked sodium hyaluronate gel can penetrate into the skin barrier so as to enter the deep skin layer, and is continuously decomposed into hyaluronic acid at the deep skin layer so as to completely moisturize the deep skin layer, fill fine lines, repair skin and restore elasticity; and the dressings, the mask and the skin care composition can provide functions of moisturizing and skin repairing, wherein the cross-linked sodium hyaluronate penetrating into the deep skin layer and providing functions from inside to outside andthe hyaluronic acid positioned on the skin surfacer and providing functions from outside to inside co-act to generate the functions of moisturizing and skin repairing, the action time is long, and theeffects of moisturizing, wrinkle removing and repair are excellent.

The invention provides an unguent for trauma, scalds and bedsores and preparation and using methods of the unguent. The unguent is processed from the following raw materials: angelica sinensis, tortoise shells, calamine, elephant hide, wadalee-gum-trees, calcined ossa draconis, gypsum rubrum, nacre mothers of pearls, gypsum, sal ammoniac, borax, realgar, olibanum, myrrh, pig nails, donkey nails, beewax, nidus vespae, borneol, musk, Chinese wax, sesame oil and lard through preparation of raw materials, processing of filter residues and decoction. The unguent provided by the invention is convenient to paste, good in curative effect and strong in infiltration capacity and has the functions of clearing heat for detumescence, relieving pain, removing toxins, cooling and activating blood, expelling pus, removing decay, diminishing inflammation and promoting granulation, so that the treatment cost can be lowered and the cure time can be shortened, and the cured scar tissues are soft and rich in resilience, and the limb function is not affected as a result of contracture of the scar tissues. The unguent has a special curative effect on acute and chronic infectious wounds which can be cured within 7-15 days, and the limb function is recovered; the unguent has a remarkable curative effect on scalds and bedsores which can be gradually cured within 7-20 days, and the skin function of the affected part is recovered.

The invention belongs to the technical field of intelligent internet of things, and especially relates to a bioelectrical impedance detection terminal based internet of things smart beauty treatment system. The system includes a bioelectrical impedance detection terminal based on m sequence bioelectrical impedance and an all phase FFT response algorithm, an intelligent mobile equipment terminal and an internet platform based on cloud computing and big data; the bioelectrical impedance detection terminal is a wearable structure, and is in communication connection with the intelligent mobile equipment terminal; the bioelectrical impedance detection terminal has a sensitive metal probe and can accurately collect data; and an independent sensing system is arranged in the bioelectrical impedance detection terminal. The wearable bioelectrical impedance detection terminal based on the m sequence bioelectrical impedance and the all phase FFT response algorithm can obtain the distribution of skin electric characteristic parameters by applying excitation current or voltage through a surface electrode array and measuring boundary voltage or current signals, and therefore, skin function characteristic data models can be rebuilt.

The invention provides repairing aloe essence which comprises barbaloin, water, methylparaben, propylparaben, sodium urate and vitamin E, wherein the barbaloin is 100% pure natural aloe essence extracted from aloe in freezing state. The repairing aloe essence disclosed by the invention realizes the repairing and rapid moisturizing effects through micromolecule with high seepage velocity, has certain repairing effect and certain curative effect on sunburned skin and skin diseases respectively, and normalizes the skin functions; as the relieving tenderness of the aloe, the repairing aloe essence is suitable for sensitive, dry, mixed and oily skin.

The invention provides a skeleton animation vertex correction method and a model learning method, device and apparatus. The method comprises the steps of collecting the whole body images and posture data of various motions including T-shaped postures of different people, and obtaining the model training data, wherein the model training data comprises the posture data P and Pm of a standard 3D mesh model, the coordinates Gr of N vertexes, N vertex coordinates T and n joint point coordinates J of a T-shaped posture 3D mesh model; constructing and training a joint position prediction model, constructing a postures regression network model and a skeleton animation vertex correction model comprising a standard skin function, the trained joint position prediction model and the postures regression network model, and training. The skeleton animation vertex correction model provided by the invention can compensate and correct the unreasonable deformation generated on the original skin surface in the movement process of a character role, so that the character role looks vivid and natural, the animation quality is improved, the workload of an animator is reduced, and the time spent on making animations with the same quality is shorter.

The invention discloses a radix gentianae compound enzyme preparation method, which comprises: S10, selecting fresh radix gentianae, swertia and centella asiatica, crushing, screening, and adding deionized water to dissolve the screened powder so as to obtain a dissolving solution; S20, adding cellulase and pectinase into the dissolving solution for enzymolysis treatment, and obtaining enzymatic hydrolysate; S30, adding yeast extract, peptone and glucose into the enzymatic hydrolysate, and then performing sterilization treatment to obtain a sterilized solution; and S40, inoculating a strain combination consisting of saccharomyces cerevisiae and lactobacillus plantarum into the sterilized solution, and performing fermentation treatment to obtain the radix gentianae compound enzyme. The radix gentianae compound enzyme prepared by the method disclosed by the invention is high in content of effective substances, can be applied to daily chemical products to strengthen skin functions and improve skin conditions, and has very good anti-allergy soothing and anti-oxidation effects.

The invention discloses an anti-aging composition and a preparation method thereof. The anti-aging composition is prepared from the following components in percentage by weight: 0.7 to 1.1 percent of vitamin A, 17 to 23 percent of vitamin E, 1.1 to 5.9 percent of sucrose stearate, 11 to 23 percent of calamine and the balance of glycine betaine. On the basis of safety and environment friendliness, by mild stimulation on the metabolic function of the skin, the anti-aging composition promotes skin function repairing, protects the skin and delays aging. The composition gives priority to taking the calamine as a carrier of oily raw materials such as functional raw materials VA and VE, owing to the fact that the calamine has relieving and curing effects on corresponding skin problems and owing to the fact that the calamine has a special surface porous structure, the calamine can absorb active substances to an extremely large extent and can uniformly convey the active substances to skin portions requiring the active substances under a condition of fully carrying the active substances due to the characteristic of easiness in dispersion, and release the active substances step by step to achieve the synergistic effect.

The invention belongs to the technical field of health and beauty products, and relates to a mask, in particular to an all natural whitening and freckle removal mask. The whitening and freckle removal mask is characterized by comprising the following raw materials in parts by weight: 4-10 parts of towel gourd powder, 5-8 parts of wax gourd juice, 1-3 parts of pearl powder, 2-5 parts of aloe juice and 2-5 parts of honey. The product is used for preventing and treating various stains and acnes on facial skin of a human body, keeping the facial skin elastic, removing wrinkles from the facial skin, and delaying senescence of the facial skin. The all natural whitening and freckle removal mask has no toxic or side effects, and has functions of nourishing and keeping the skin healthy. The mask is very popular with mass females.

The invention relates to the technical field of medicine, and in particular relates to an anti-aging biological preparation for regulating incretion. The biological preparation comprises the following components by mass: 60-70 parts of water, 0.8 part of diosgenin, 0.1 part of honokiol, 1 part of honeysuckle extract, 0.1 part of hyaluronic acid, 0.5 part of soybean peptides, 3 parts of Simmondsia Chinensis Seed Oil, 6 parts of cetostearyl alcohol, 2 parts of hydrogenated castor oil, 2 parts of cetearyl glucoside, 3 parts of propylene glycol, 0.5 part of safflower seed oil, 1 part of glyceryl stearate, 0.1 part of ethylenediaminetetraacetic acid, 0.1 part of sodium benzoate, 3.5 parts of caprylic / capric triglyceride, 5 parts of red ginseng extract, 5 parts of Rhodiola extract, 0.2 part of keratin, 3 parts of Epimedium extract, 10.1 parts of ceramide 1 and 1 part of peony root bark extract. The anti-aging biological preparation can regulate body incretion to a normal state, and can comprehensively improve skin functions.

The invention relates to a human pluripotent stem cell exosome loaded with photosensitive drugs and preparation and a use thereof. The photosensitive drug is 8-methoxypsoralen, 5-methoxypsoralen, trimethoprim or a traditional Chinese medicine photosensitizer. Compared with the prior art, the exosome derived from embryonic stem cells and induced human pluripotent stem cells is used as a photosensitive drug carrier including 8-methoxypsoralen, constructs a powerful nano-drug delivery system for promoting skin pigment secretion and improving skin functions, and can be used for treating leucoderma, parapsoriasis guttata, psoriasis and other refractory skin diseases.

The invention discloses an emulsion which contains bletilla striata root extract and is capable of removing acne. The emulsion comprises natural plant components such as the bletilla striata root extract, radix scutellariae extract and mentha haplocalyx extract. The emulsion has the advantages that the three components are complementarily and scientifically compounded to achieve effects such as clearing away heat and toxic materials, regulating skin grease balance, inhibiting bacteria and diminishing inflammation, eliminating free radicals, nourishing the skin, supplementing skin collagen and increasing skin elasticity, and the emulsion is evident in acne removing effect and has effects of whitening and resisting oxidation; the emulsion contains the bletilla striata root extract capable of repairing skin functions, is capable of promoting the synthesizing of wound surface cell DNA, increasing cell proliferation ability, providing nutrition for cell proliferation and increasing skin collagen fibers and is helpful to the repairing of damaged skin caused by the acne.

The present invention relates to a three-dimensional negative pressure stimulator module capable of performing customized composite stimulation for the improvement of skin functions that applies three-dimensional negative pressure stimulation as well as composite stimulation such as electric current stimulation, light stimulation, and thermal stimulation, which is helpful in improving functions of the skin, to skin compositively, and further has a function of sensing a skin state, thereby performing customized composite stimulation. The three-dimensional composite stimulator module includes: a negative pressure cup; and at least one diaphragm provided along the transmission path of the negative pressure of the negative pressure cup, wherein at least any one of negative pressure stimulation, light stimulation, thermal stimulation, and electrical stimulation is transmitted compositively to the skin or subcutaneous tissues.

A method of screening a material for improving skin functions includes: (a) treating a skin cell with a candidate material; (b) detecting a change in a relative expression level of membrane-associated protein 17 (MAP17) gene; and (c) selecting a candidate material inducing the change in the expression level of the gene as a material for improving skin functions.

That is to say, a material for improving skin functions is screened using MAP17 gene as a marker, on the basis of the change in the expression level of the MAP17 gene. A material for improving skin functions, which is useful in improving skin barrier function, promoting skin moisturization, preventing skin aging, or ameliorating skin troubles, may be effectively screened.

A disclosed cosmetic composition comprises the following compositions in parts by weight: 2-20 parts of a plant extraction liquid, 3-11 parts of a moisture-retaining agent, 0.2-0.4 part of a thickening agent, 0.1-0.5 part of an emulsifier, 0.1-2 parts of quartz stone, 0.03-0.07 part of potassium hydroxide, 0.055-0.88 part of a pH conditioner, 0.8-4 parts of an antiseptic, and 60-90 parts of water. The plant extraction liquid comprises a herba houttuyniae extraction liquid and a Chinese fevervine herb extraction liquid, and the antiseptic comprises a pogostemon cablin extraction liquid. According to the cosmetic composition, a mixed solution of the herba houttuyniae extraction liquid and the Chinese fevervine herb extraction liquid is applied to cosmetic compositions, skin functions are effectively improved and dermatitis is prevented.

The invention discloses a cosmetic composition having effects of increasing skin elasticity and resisting wrinkle and an application thereof. The cosmetic composition contains 0.01% to 1.0% of ceramide, 0.001% to 0.1% of palmitoyl oligopeptide, 0.05% to 1.0% of royal jelly and 0.25% to 5% of lecithin. The weight ratio of royal jelly (on a dry weight basis) to lecithin is 1: 5. The cosmetic composition exists in a form of a two-layer lipsome aqueous solution with particle diameters of 30 nm to 130 nm. The cosmetic composition contains ceramide, palmitoyl oligopeptide, royal jelly and lecithin.The cosmetic composition can improve skin wrinkles, improve skin elasticity and recover skin functions. The two-layer lipsome aqueous solution improves the stability of royal jelly in the product andhelps the skin to absorb royal jelly.

The invention discloses a biological dressing with a skin repairing function. The biological dressing is composed of a substrate and a liquid medicament attached to the substrate; raw preparation materials of the liquid medicament contain active peptide, growth factors, a hyaluronic acid composition, glycerin, mushroom glucan, polygonatum sibiricum polysaccharide, phloretin, prinsepia utilis rogleoil, an aloe extract, a white fungus extract, a sophora davidii flower extract, a herba pteridis multifidae extract and a honey extract. According to the biological dressing, through the cooperativeuse and synergism of hyaluronic acid, the growth factors and the plant extracts, the composition with the functions of moisturizing, repairing, swelling removal and oxidation resistance is obtained. The composition can be used as the medial dressing for treating and nursing dermatitis, eczema, skin allergies and superficial injuries (such as sunburn).

The invention relates to a traditional Chinese medicine health-preserving medicated bath preparation. The preparation comprises radix isatidis, tea stem, cyrtomium rhizome, herba ephedra, radix salviae miltiorrhizae, radix codcnopsitis pilosulas, radix scrophulariae, radix adenophorae, radix puerariae, rhizoma anemarrhenae, rhizoma coptidis, rhubarb, radix sophorae subprostratae, ginseng juice, honey, arenaria kansuensis herb, mistletoe, fructus tsaoko, areca nut, fructus momordicae, fructus canarii, glossy ganoderma, stigma croci, camellia flower, globeamaranth flower, momordica grosvenori swingle flower, jasmine flower, myosotis sylvatica, peach flower, marigold, ginseng flower, sandalwood, sappanwood, dalbergiawood, camphorwood, pinewood, cedarwood, elderberry, radix arnebiae seu lithospermi, lemongrass, lysimachia foenum-graecum, herba hedyotis diffusae, lavender, lotus leaves, tea leaves and linden leaves. When the preparation is used for medicated bath, the effects of cleaning the skin, realizing sanitation, relaxing the muscles for stimulating the blood circulation, resisting wind-cold, improving the skin function, enhancing the immunity and preventing diseases can be achieved.

The invention belongs to the technical field of cosmetics and discloses an oil control convergence package and a use method thereof. The oil control convergence package comprises oil control convergence emulsion, oil control convergence essence and oil control convergence water. A brand-new oil control technology is adopted in the oil control convergence package, a super-strong matching effect of active ingredients is fully played, and particularly, sebum synthesis can be remarkably reduced by matching a bixa orellana seed extract with PCA zinc and zinc gluconate, excessive sebum overflow is removed, toxicity of bacillus acnes on the skin is reduced, excessive keratinization is inhibited, medicinal fomes have effects of reducing pores, and tightening and moisturizing the skin, a convergence effect of hamamelis mollis is exerted, oil secretion can be obviously controlled, water-oil balance of the skin is helped to be adjusted, a skin function is improved, young vigor muscles are created, the skin is clear and healthy, fine and transparent effects are achieved, and a problem that oily skin is oily outside and dry inside is solved.

The present invention relates to cosmetic material compositions for skin whitening or skin anti-aging containing Averrhoa bilimbi extract as an active ingredient. The active ingredient of each composition further contains selectively at least one selected from the group consisting of Gynura procumbens extract and Gynura pseudochina extract. According to the cosmetic material composition of the present invention, skin function can be effectively improved without skin irritation through, for example, enhancing skin whitening or preventing the aging of skin.