70 results about "Elastin peptides" patented technology

The invention discloses a beverage capable of maintaining beauty and nourishing the skin and a preparing method of the beverage. The beverage capable of maintaining beauty and nourishing the skin is prepared from collagen tripeptide, chitosan oligosaccharide, gamma-aminobutyric acid, fish collagen peptide and skipjack elastin peptide. The beverage achieves great effects of adjusting and repairingthe skin of the human body in combination with multiple collagen nutrients, vitamin C and nutrient substances resistant to sugar and oxidation required for the human body.

The present invention is directed to a composition which is used to enhance the elasticity and / or appearance of tissue. Specifically, the present invention is directed to a composition formulated from peptides having low molecular weights and which substantially correspond to sequences found in elastin More preferably, the present invention corresponds to the general formula R1-Leucine-Glycine-Alanine-Glycine-Glycine-Alanine-Glycine-R2.

Methods for producing and using protein / peptide fingerprints, allowing identification and investigation of disease-associated proteins / peptides that can be linked to specific drug targets, or to specific drug target combinations. The methods are particularly useful for studies relating to Chronic Obstructive Pulmonary Disease (COPD), especially for the enzyme MMP12.

The invention discloses a composition capable of improving skin moisture and elasticity and eliminating wrinkles. Main active ingredients of the composition are collagen peptide and elastin peptide. The composition also comprises the following active ingredients: sodium hyaluronate and Chinese herb extracts. The invention further provides application of the composition in preparation of health-care food capable of improving skin moisture and elasticity and eliminating wrinkles. The dosage form of the health-care food prepared from the composition may be an oral liquid, a capsule, a tablet, a powder, an effervescing agent, a granule or the like. According to the invention, the active ingredients in the composition cooperate and coordinate, and the effects of skin moisture improvement, skin elasticity improvement and wrinkle elimination are realized at a plurality of levels in a plurality of ways; and combined usage of the active ingredients--compound peptide, the Chinese herb extracts and sodium hyaluronate exerts a synergistic effect on improvement of skin moisture and elasticity and elimination of wrinkles.

The present invention relates to skin care compositions providing a method of enhancing the remodeling of age damaged and sun damaged skin in mammals utilizing an elastin peptide (EP) ligand of the general formula (GXXPG)n and in particular the sequences of (VGVAPG)n and / or (GVAPGV)n, and / or (VAPGVG)n and / or (APGVGV)n and / or (PGVGVA)n and / or (GVGVAP)n and a galactosugar which modulates the effect of the elastin peptide ligand(EP) on its lectin the Elastin-Binding Receptor (EBR). wherin A is a peptide-forming residue of L-alanine; G is a peptide-forming residue of glycine P is a peptide-forming residue of L-proline V is a peptide-forming residue of L-valine X is a peptide-forming residue of a single unspecified amino acid Peptide representations in this application conform to the standard practice of writing the NH2-terminal amino acid residue at the left of the formula and the CO2 H-terminal amino acid residue at the right.

The invention discloses a functional peptide with the cosmetic efficacy and a preparation method and an application thereof. The functional peptide is a composite product of an elastin peptide and a collagen peptide, and the preparation method of the functional peptide with the cosmetic efficacy includes the following steps: soaking elastin raw materials with a NaCl solution to remove oil, and soaking collagen raw materials with a NaOH solution to remove oil; then conducting centrifugation or mincing to obtain an elastin crude extract and a collagen crude extract, and then mixing the elastin crude extract with the collagen crude extract, conducting enzymatic hydrolyzing with protease, and then spray drying the obtained enzymatic hydrolysate to obtain the functional peptide with the cosmetic efficacy. According to the preparation method, the elastin and collagen are simultaneously treated by a biological enzymolysis technology, while the elastin peptide and the collagen peptide with the cosmetic efficacy are released, the elastin peptide and the collagen peptide are better mixed during the enzymatic hydrolysis process. The composite product of the elastin peptide and the collagen peptide, prepared by the method, has the obvious efficacy of moisturizing and resisting wrinkle, and can significantly improve the moisture content and the collagen content in the skin.

The invention relates to a cubilose and collagen peptide beverage. The cubilose and collagen peptide beverage is characterized by being prepared from the raw materials in percentage by weight: 8-18% of fish collagen peptides, 0.1-0.6% of cubilose powder, 1-3% of a blueberry concentrated solution, 2-4% of a passion flower concentrated solution, 1-3% of an apple concentrated solution, 0.05-0.3% of inulin, 0.1-1% of tremella polysaccharide, 0.1-0.3% of cherry powder, 0.1-0.8% of red grape concentrated fruit powder, 0.1-0.3% of stachyose, 0.5-2% of elastin peptides, 0.1-0.6% of gamma-aminobutyricacid, 0.1-1% of haematococcus pluvialis, 0.03-0.07% of a food additive, 0.01-0.03% of an essence for food, and the balance of pure water. The invention further discloses a preparation method of the cubilose and collagen peptide beverage. Two major functional components, namely cubilose and collagen peptides, of the cubilose and collagen peptide beverage disclosed by the invention complement each other, the curative effect can be exerted better, the nutrition of the cubilose and collagen peptide beverage is rich, the translation speed of a taker can be effectively increased, memory of the takercan be effectively improved, reactivation of cells and generation of collagen are promoted, nourishing before delivery, after delivery and after illnesses is facilitated, and nutrients daily essential to human bodies are supplemented.

The invention discloses elastic protein peptide powder. The key points of the technical scheme are characterized in that the elastic protein peptide powder is prepared from the following components inparts by weight: 2,300-2,700 parts of fish collagen hydrolysate, 600-800 parts of blueberry juice powder, 600-800 parts of grape powder, 230-270 parts of cranberry juice powder, 50-350 parts of xylitol, 90-130 parts of green plum powder, 80-120 parts of acerola cherry fruit powder, 40-80 parts of type II collagen peptide hydrolysate, 80-120 parts of L-calcium lactate, 30-70 parts of soybean peptide, 8-14 parts of skipjack elastic protein peptide, 2-5 parts of blood orange powder, 10-14 parts of cubilose peptide, 80-120 parts of beet juice powder, 60-80 parts of citric acid and 1-5 parts of sucralose. The invention aims at providing the elastic protein peptide powder which can remarkably improve skin ageing.

The present invention provides compositions for the therapeutic and / or cosmetic treatment of Elastin comprising tissues. Therapeutic and cosmetic compositions comprising an elastin digest stimulate the endogenous production of Elastin and appear to enhance the elasticity of the skin and provide an external supply of peptide precursors of Elastin that penetrate into the tissue to which it is applied. The present invention describes compositions containing an elastin digest derived from proteolytic digestion of insoluble elastin derived from mammalian ligaments with a protein digesting composition, such as proteinase K. The elastin digest is a mixture of elastin peptides wherein the elastin peptide mixture comprises peptides of the sequence GXXPG, wherein X represents one of the natural amino acids. The elastin digest of the present invention may also comprise epitopes of cytokines, growth factors and di-peptides. Methods of using these elastin digest comprising compositions for treating tissues in need of increased elasticity and or Elastin are described.

The invention belongs to the field of health care food, and particularly relates to a food composition with moisturizing, anti-senile, skin-tightening, spot-fading and whitening function and a preparation method thereof. The composition is prepared from the following ingredients including skipjack elastic protein peptides, fish collagen peptides, inulin, blackcurrant powder, vitamin C and needle leaf cherry powder. The composition obviously relieves the fishy and odor smell; the bitter taste is well shielded; the moisture preservation performance is good; the hydrolysis purity of elastic protein peptides is high; impurity peptides are few; the elastic protein peptides and the collagen peptides achieve the mutual promotion with other ingredients, so that good beautification and health careeffects can be achieved under the condition of low-consumption composition.

The present invention is directed to a composition which is used to enhance the elasticity and / or appearance of tissue. Specifically, the present invention is directed to a composition formulated from peptides or peptide-like compounds having low molecular weights and which substantially correspond to sequences found in elastin. The present composition specifically includes chemical modification of the peptides described herein, specifically carboxy and amino modification including the addition of amino acids to either end of the peptide fragments.

The invention provides an ocean dietary composition for postpartum lactation recuperation and a preparation method thereof. The ocean dietary composition comprises skipjack elastin peptide, enzymolytic octopus protein powder, ocean fish oligopeptide powder, colla corii asini peptide powder, pawpaw extract, Chinese yam extract, red dates powder, concentrated wild jujube juice, concentrated medlar juice, water-soluble dietary fiber and mineral. The composition is conducive to promoting puerpera milk secretion, improving breastfeeding quality, promoting puerpera breast recovery and lowering puerpera depression trend. In addition, the composition combines ocean functional factors with conventional traditional Chinese medicine theories and is unique in formulation, simple and convenient in technological process and suitable for industrial production.

The invention relates to the field of skin-care products and health-care solid beverage, in particular to an elastin peptide composite solid beverage capable of resisting wrinkles, preserving moistureand improving skin elasticity and a preparation method thereof. The elastin peptide composite solid beverage of the invention is prepared by modern technological means, and composed of collagen oligopeptides, bastard halibut meal, chitosan oligosaccharides, cowhells elastin peptide, erythritol, strawberry fruit powder, raspberry fruit powder, maltodextrin and gamma-aminobutyric acid, citric acid,sucralose, and vitamins-C. Experiments prove that the elastin peptide composite solid beverage of the invention has a very ideal effect of resisting wrinkles, preserving moisture and improving skin elasticity. In addition, the elastin peptide composite solid beverage of the invention also has the functions of scavenging free radicals, whitening skins, delaying aging and the like.

The present invention is directed to a composition which is used to enhance the elasticity and / or appearance of tissue. Specifically, the present invention is directed to a composition formulated from peptides or peptide-like compounds having low molecular weights and which substantially correspond to sequences found in elastin. The present composition specifically includes chemical modification of the peptides described herein, specifically carboxy and amino modification including the addition of amino acids to either end of the peptide fragments.

The invention provides a collagen peptide beverage. The beverage is prepared by mixing 13-15 parts by weight of collagen peptide, 0.016-0.024 part by weight of elastin peptide, 0.11-0.2 part by weightof tremella polysaccharide, 0.16-0.24 part by weight of chitosan oligosaccharide and 0.02-0.2 part by weight of vitamin C, and adding a proper amount of water for constant volume of 100 parts by weight. The molecular weight of the collagen peptide is 800-1000 Daltons, and the molecular weight of the elastin peptide is 500-3000 Daltons. The beverage contains collagen peptide, elastin peptide, tremella polysaccharide, chitosan oligosaccharide and vitamin C, not only can supplement collagen, elastin and hyaluronic acid at the same time, but also can stop skin saccharification and stop skin oxidation, so that the skin becomes watery, tender and highly elastic, has no wrinkle, and is not easy to generate phenomena of black spots or dull yellow and lifeless skin.

The present invention is directed to a composition which is used to enhance the elasticity and / or appearance of tissue. Specifically, the present invention is directed to a composition formulated from peptides having low molecular weights and which substantially correspond to sequences found in elastin. These peptides are used in conjunction with or in combination with retinoids, preferably tretinoin.

The invention discloses a health-care oral liquid taking aronia as a main raw material. The health-care oral liquid is prepared from the following components in parts by weight: 20-30 parts of aroniajuice; 15-25 parts of red raspberry juice; 5-15 parts of blueberry juice; 6-10 parts of fish collagen peptide; 4-8 parts of acerola cherry powder; 2-4 parts of natto freeze-dried powder; 2-4 parts ofelastin peptide; 2-4 parts of curcumin; 2-4 parts of a grape seed extract; 2-4 parts of an evening primrose extract; 2-4 parts of cranberry juice; 2.5-3 parts of inulin; 1-3 parts of blood orange powder; 1-3 parts of matcha powder; 1-3 parts of purslane herb extract; 1-3 parts of an enzyme extract; and 1-3 parts of haematococcus pluvialis. The oral liquid achieves the effects of beautifying skins,resisting aging, effectively removing garbage in the body, resisting oxidation, promoting deep sleep and maintaining female ovaries, and facilitates rejuvenation of vast male and female sibs.

The invention relates to the fields of face cream and health-care beverages, in particular to a collagen composite beverage capable of resisting wrinkles, moisturizing and improving skin elasticity and a preparation method of the collagen composite beverage. The collagen composite beverage is prepared from hydrolyzed II-type collagen, salmon meal, white fungus liquid, striped tuna elasticity protein peptide, casein hydrolyzed peptide, apple juice concentrate, pomegranate condensed juice, pectin, high fructose corn syrup, citric acid, cane sugar pigment, DL-malic acid, nicotinamide, niacin, pyridoxine HCl, vitamin B6 and edible essence through a modern technical means. Test proves that the collagen composite beverage has ideal effects of resisting wrinkles and moisturizing. In addition, thecollagen composite beverage also has the effects of improving skin elasticity, eliminating free radicals, whitening skin, delaying senescence and the like.

The invention relates to the technical field of food and medicines, and discloses a composition of a collagen peptide and an elastin peptide, and a preparation method and application of the composition. The composition of the present invention is composed of a collagen peptide and an elastin peptide, wherein the collagen peptide is produced by enzymolysis of a collagen material by pepsin or trypsin, and the elastin peptide is prepared by enzymolysis of an elastin material via papain and / or a complex protease Protamex. According to the present invention, the elastin peptide and collagen peptidein specific molecular weight ranges are prepared by specific processes, and form the composition at a suitable ratio. The composition can significantly increase the content of elastin and collagen indamaged skin at the same time in a small amount of use, significantly increase the content of hyaluronic acid and hydroxyproline and decrease the content of MMP3, and also can inhibit skin inflammatory factors.

The present invention describes therapeutic compositions comprising fibroblasts that have been stimulated to increase expression of extracellular matrix components or elastin, or to produce enhanced elastogenesis or the appearance thereof at a site of administration. The therapeutic fibroblast formulations can be prepared using a variety of elastogenic agents, including digests of mammalian elastin, chemically digested plant extracts comprising elastin-like peptides, and synthetic elastogenic peptides. The invention further comprises cosmetic and pharmaceutical treatment methods using the therapeutic fibroblast compositions of the invention.

The invention discloses a method for extracting elastin peptide, belonging to the technical field of extraction of bioactive substances. The method comprises the steps of removing impurities such as fish meat from fish cartilage, washing and mincing, and soaking in an ethanol solution; adding a Tris-HCl buffer solution, and carrying out ultrasonic treatment; adding elastase, and performing shakingculture in a constant temperature water bath; carrying out suction filtration on enzymatic hydrolysate after enzyme deactivation, discarding filter residues, and collecting filtrate; enabling the filtrate to be subjected to primary ultrafiltration, and collecting permeate; enabling the permeate to be subjected to secondary ultrafiltration, and collecting ultrafiltrate; dialyzing and desalting theobtained ultrafiltrate, carrying out rotary evaporation, and carrying out freeze-drying to obtain the elastin polypeptide. The method for extracting the elastin peptide is simple and rapid, high in extraction rate and low in cost. The prepared elastin polypeptide is strong in reducing power, is capable of effectively scavenging free radicals, is good in antioxidant effect and can significantly increase the content of collagen peptide in the skin. The method has a wide application value in the industries of food, cosmetics and medicine.

The invention discloses whitening and anti-aging fruit juice drink and a preparation method thereof. The fruit juice drink is prepared from the following components: passion fruit juice, collagen tripeptides, yeast extract, acerola cherry powder, olive fruit powder, rice bran oil powder, bonito elastin peptides, acai fruit powder, citric acids, L-malic acids, sodium citrate, potassium sorbate, sucralose, mogroside and purified water. The preparation method includes the following five steps of cleaning and disinfection, mixing raw materials, filtration, concentrated and diluted sterilization. The whitening and anti-aging juice drink and the preparation method thereof have the advantages of fruit taste, good taste, safety, skin anti-aging; and skin elasticity can be enhanced, skin wrinkles are improved, and the skin moisture function is added.

The invention aims to provide an anti-aging injection. The anti-aging injection comprises elastin peptide, and is characterized by further comprising human adipose-derived mesenchymal stem cell culture medium supernatant and seaweed extract. Adipose-derived stem cells and the elastin peptide are combined and are assisted by seaweed extract liquor, synthesis of elastin can be promoted, activity ofelastase is inhibited, proliferation and differentiation of epidermal cells are promoted by the aid of vitamin C, oxygen free radicals are removed, skin repair of injured portions is promoted, growthand differentiation of skin cells are promoted by vitamin A, a hematopoietic function of surface skin is enhanced, the structure of skin elastic tissues is reconstructed essentially, and aging of human skin is delayed. The adipose-derived stem cells and the elastin are combined and are assisted by the seaweed extract liquor for facial lifting, the problems of facial sagging, non-elasticity of skinand the like caused by aging of the skin can be solved fundamentally, and a good wrinkle removing effect is achieved.

The present invention relates to the technical field of milk products and in particular to a formula milk powder with a cosmetic effect and a preparation method of the formula milk powder. The formulamilk powder includes an organic whole-milk powder, a fish collagen peptide powder, a cranberry powder, N-acetylneuraminic acid, an elastin peptide powder, vanilla planifolia and a haematococcus pluvialis powder, wherein the cranberry powder and the haematococcus pluvialis powder are respectively obtained by smashing raw materials, performing enzymolysis and drying to form a powder, then, treatingthe powder by adopting long-chain saturated fatty acid and fatty acid monoglyceride, and then, drying the powder. According to the formula milk powder with the cosmetic effect, provided by the present invention, it is firstly proposed that the cranberry powder and the haematococcus pluvialis powder which serve as biomass raw materials with cosmetic effects in a cosmetic formula milk powder are treated by adopting the long-chain saturated fatty acid and the fatty acid monoglyceride to ensure that the surfaces of the biomass raw materials are coated and modified by using grease, so that a biomass raw material powder is favorably isolated from the air, the phenomenon that bacteria are attached to the biomass raw material powder after the biomass raw material powder adsorbs water in the air is avoided, and furthermore, the storage period of the milk powder is greatly prolonged.

The invention discloses a multi-effect cream capable of promoting skin fibroblasts to secrete structural proteins. The cream consists of, in parts by weight, 20-24 parts of elastin peptide liposome, 170-190 parts of water, 0.3-0.7 part of carbomer, 10-15 parts of glycerin, 1-2 parts of allantoin, 13-17 parts of mineral oil, 0.2-0.3 part of propyl hydroxybenzoate, 0.2-0.3 part of methyl hydroxybenzoate, 0.3-0.6 part of poly(dimethylsiloxane), 11-15 parts of cetostearyl alcohol, 0.07-0.1 part of essence, 0.8-1.5 parts of tocopheryl glycoside, 0.15-0.25 part of borneol, 2.5-3 parts of glyceryl monostearate, 1.0-1.5 parts of Tween 20, 6-9 parts of propylene glycol, 9-11 parts of shea butter, 0.4-0.6 part of ethylene diamine tetraacetic acid disodium salt and a proper amount of 2-amino-2-methyl-1-propanol. The elastin peptide liposome in the cream can be effectively absorbed by skins, so that the elasticity of facial skins can be recovered.

The invention provides a compound beverage having whitening and wrinkle preventing efficacies. The compound beverage is prepared from the following main raw materials: chitosan oligosaccharide, a ricebran extract, skipjack elastin peptide, salmon extract protein powder, fish collagen protein peptide, apple concentrate, grapefruit concentrate, vitamin C, and the like, which are synergistic and cooperative, thus greatly improving the whitening and wrinkle preventing efficacies. The compound beverage disclosed in the invention has high stability.

The invention relates to a composition with functions of resisting blue light and improving skin quality and an application of the composition. The composition is mainly prepared from the following raw materials in parts by weight: 5-50 parts of fish collagen peptide, 0.01-5 parts of skipjack elastin peptide, 0.05-0.1 part of xanthophyll, and 0.01-0.1 part of zeaxanthin, wherein the weight ratio of the fish collagen peptide to the skipjack elastin peptide is (5-10): 1. The functional composition not only has the effects of improving skin elasticity and delaying skin aging, but also has the functions of resisting blue light and reducing skin injury.

The invention provides a composition for resisting a thrombus as well as a preparation method and application thereof, and belongs to the technical field of biology. The composition for resisting thethrombus is prepared from the following raw materials in parts by weight: 10 to 40 parts of concentrated natto powder and 1 to 10 parts of skipjack elastic protein peptide. The composition for resisting the thrombus is obtained by mixing the concentrated natto powder and the skipjack elastic protein peptide. The application of the composition prepared by the preparation method in the preparation of a thrombus-resisting medicine, a health product or food such as new-resource food is wider, and the composition is healthy and safe, has no toxic and side effects, is good in thrombus resisting effect, moreover, can be used for reducing blood fat, and is used for increasing the immunologic function of a patient.

The invention relates to the technical field of food or health care products, and in particular, relates to a skipjack elastin peptide and collagen oligopeptide composition and a preparation method thereof. The skipjack elastin peptide and collagen oligopeptide composition comprises the preparation raw materials in parts by weight: 750-870 parts of collagen oligopeptide and 5-12 parts of elastin peptide. The composition can resist skin aging, activate human corium layer fiber cells and remarkably promote synthesis of human collagen and elastin, and has the effect of keeping skin elasticity; and moreover, the skin elasticity and softness can be improved, the vascular elasticity can be enhanced, the vascular aging can be relieved, the ligament cell proliferation can be promoted, the ligament function can be improved, the joint stabilizing effect can be improved, the motor function can be consolidated and recovered, and ligament ossification can be inhibited.