The invention discloses cefodizime sodium for injection and a preparation method of the cefodizime sodium. A dispensation comprises the cefodizime sodium, the cefodizime sodium is contained in a glassbottle, a rubber plug is plugged at the bottle opening of the glass bottle, an aluminum-plastic cover is arranged at the top of the rubber plug, and the aluminum-plastic cover is capped at the bottomopening of the glass bottle. The preparation method of the cefodizime sodium for injection comprises the following steps that 1, a raw material is selected; 2, the raw material is preprocessed; 3, the raw material is subpackaged; 4, capping and sealing are conducted; 5, detecting and marking are conducted; and 6, labelling and packing are conducted, and a raw material drug, a glass bottle, a rubber plug and a plurality of aluminum-plastic covers are selected for standby application. According to the cefodizime sodium for injection and the preparation method of the cefodizime sodium, the wholemanufacturing process is clean, the hygienic conditions are good, the manufacturing process is smooth, seamless transition is achieved, the pharmacy efficiency can be greatly improved, the process isprecise, detection is strict, the quality of products can be effectively guaranteed, meanwhile the cost is controlled, waste is less, and generalization is convenient.