163results about How to "Definite clinical efficacy" patented technology

The invention relates to an extract of persimmon leaves which are rich in flavones and a process for preparation, and the usage for preparing medicaments and/or health products for preventing and/or curing glucose and lipid metabolism and the relative illness, wherein glucose and lipid metabolism and the relative illness comprise hyperglycemia, diabetes mellitus and metabolism syndrome. Pharmacological researches, animal in vivo experiments and clinical researches show that the extracts of persimmon leaves which are rich in flavones have obvious functions of decompression, antihyperglycemic and antihypelipidemic, clinical curative effects for curing metabolism syndrome of diabetes, hyperlipemia, and hypertension are precise, and a toxicity test shows that the toxicity of the extracts of persimmon leaves which are rich in flavones of the invention is lower, and the security is high.

The invention discloses high-purity syringin, a preparation method and application. The current domestic extraction process has quite high cost and is not suitable for industrialized production. The method comprises dissolution, macroporous absorbent resin chromatography, decolorization, crystallization and recrystallization, wherein a, the dissolution comprises dissolving acanthopanax paste by 10to 30 times of water, then keeping the solution standing and centrifugating the solution; b, the chromatography comprises filtering the centrifugated solution and then filling the centrifugated solution in a macroporous resin chromatography column, removing impurities by water, removing the impurities and desorbing the solution by alcohol with low concentration, collecting components of the syringin by segmenting, and reducing the pressure and concentrating the components; c, the concentrated solution decolorization comprises collecting the part containing the syringin; d, the collected solution re-chromatography comprises removing the impurities and desorbing the solution by lower than 10 percent low-grade alcohol, collecting components of which purities are more than 85 percent by segmenting, and reducing the pressure and evaporating the solution; and e, the solution is crystallized or recrystallized by ethanol of different concentrations to obtain the high-purity syringin. The extracted syringin has low cost, and creates the condition for wide application of medicine produced by the raw materials.

The invention discloses a preparation method and a detection method of a roflumilast material. The preparation method comprises the following steps: mixing 3-cyclopropyl methoxy group-4-difluoro methoxy group benzoic acid SM-1, thionyl chloride, dimethyl formamide with toluene, and carrying out an acylating chlorination reaction to obtain a midbody 1; mixing 3,5-dichloro-4-aminopyridine SM-2, tetrahydrofuran with potassium tert-butoxide and carrying out a salt forming reaction to obtain tetrahydrofuran solution of a midbody 2; and then mixing the midbody 1 and the midbody 2 with tetrahydrofuran, carrying out amidation to obtain a crude product of roflumilast, and refining the crude product of roflumilast to prepare the roflumilast material. Aiming to overcome the shortage of the prior art, the preparation process of the roflumilast material is optimized, so that the curative effect for treating diseases such as chronic obstructive pulmonary disease (COPD) is more remarkable; and besides, a systematic, complete and effective composition identifying and content measuring method is provided, so that the quality of the medicine can be effectively controlled, and the clinical effect is ensured.

The invention discloses a medicine composition for treating chronic ulcerative colitis. The medicine composition comprises, by weight, 90-150 parts of humifuse euphorbia herb, 10-60 parts of lucid ganoderma, 60-120 parts of garden burnet, 50-150 parts of folium callicarpae pedunculatae, 20-100 parts of radix sophorae flavescentis, 20-80 parts of hairyvein agrimony, 50-110 parts of madder, 10-70 parts of Poria cocos, 10-70 parts of Semen Euryales, 10-80 parts of Cacumen biotae, 10-80 parts of pagoda tree flowers, 10-70 parts of cuttlebone, 5-40 parts of gallnut, 10-70 parts of rhizoma bletillae, 0-40 parts of Acacia catechu and 0-40 parts of pseudo-ginseng. A preparation process of the medicine composition comprises the steps of weighing out all pharmacodynamic raw materials according to a formula and uniformly mixing all pharmacodynamic raw materials through crushing, water extraction concentration, alcohol extraction concentration or a method combining the crushing, the water extraction concentration and the alcohol extraction concentration, so that the medicine composition can be obtained. The medicine composition is prepared with Chinese herbal medicines serving as raw materials, can relieve internal heat, promote tissue regeneration and support healthy energy, is particularly applicable to treatment of ulcerative colitis, Crohn's diseases, chronic colitis, radioactive colitis and proctitis, irritable bowel syndrome and the like and can solve the problems that antibiotics are taken for a long term, beneficial bacterium drugs are not ideal in effect and toxic and side effects are large.

The invention relates to traditional Chinese medicine composition for treating hypermenorrhea, containing: gen-seng, Radix Astragali, bighead atractylodes rhizome, honey-fried licorice root, rattletop, donkey-hide gelatin, rehmanniae radix, cattail pollen, motherwort, flying squirrel feces, pseudo-ginseng and madder. Pharmacal excipient is added to prepare medicinal preparation, which may be oral liquid, capsules, pills, electuary, or tablets. The traditional Chinese medicine composition of the invention is based on the basic theory of traditional Chinese medicine, which has definite clinic therapeutic effect, is safe to take, and has no toxic and side effect.

The invention relates to a high-purity salvianolic acid B and a preparation method and application thereof. The defects of the prior art are that the purity of the obtained salvianolic acid B is lowerthan 92 percent, the steps for obtaining the salvianolic acid B of which the purity is above 92 percent are quite a lot, the cost is very high, and the prior art cannot be applied to industrial production. The preparation method consists of the steps of extraction, pre-column, polyamide chromatography and collection, wherein the pre-column comprises the following steps: filtering an extracting solution and then putting the same on a DA-201 type polar resin column, and using water to remove impurities firstly; then using low-concentration lower alcohol with 1 to 5 carbon atoms to remove the impurities; using the lower alcohol with 1 to 5 carbon atoms to perform desorption; collecting the components containing the salvianolic acid B section by section; and performing decompression and concentration. The salvianolic acid B is applied to the medicaments for treating cardiovascular and cerebrovascular diseases, kidney diseases, pneumonia, pulmonary heart diseases, pancreatitis, diabetes, cervical spondylosis, retinal vascular diseases, retinal nerve diseases, migraine headaches, chronic gastritis, dizziness, bone diseases, and Alzheimer's diseases.

Disclosed is a Chinese medicinal gelling agent which comprises, 7.5-12.5 wt% of mentha-camphor, 5.5-8.5 wt% of curcuma longa pieces, 5.5-8.5 wt% of dahurian angelica root pieces, 2.5-4.4 wt% of pollen pieces, 2.5-4.4 wt% of red peony root pieces, 2-4 wt% of nitrogen ketone, 1.5-3 wt% of Carbomer, 0.3-0.5 wt% of polysorbate, 0.1-0.3 wt% of triethanolamine and balancing water. The invention also discloses the preparing process.

An acetylglutamide injection for improving brain function and treating coma, palsy, hypointelligence, dysmnesia, etc is prepared through mixing acetylglutamide and phosphate buffering liquid, ultrasonic treating, cold storage, ultrafiltration, mixing with Na2EDTA solution in dark condition, pouring in containers, sterilizing and lamp examining.

The invention discloses application of a compound traditional Chinese medicine to prevention and treatment of an osteoporosis disease, belonging to new application of the traditional Chinese medicine. The compound traditional Chinese medicine is prepared from the following Chinese medicinal herbs in percentage by weight: 15-35 percent of glossy privet fruit, 10-25 percent of Japanese thistle herbor root, 5-20 percent of largehead atractylodes rhizome, 5-20 percent of root of red-rooted salvia, 5-15 percent of coptis root, 5-15 percent of pseudo-ginseng root, 5-15 percent of eucommia and 5-15percent of fingered citron. As proved by an experiment, the compound traditional Chinese medicine has remarkable treatment effects on the prevention and treatment of primary osteoporosis, secondary osteoporosis, osteoporosis caused by hyperlipidaemia or an osteoporosis disease caused by glucose metabolism syndrome, definite clinical curative effect and no remarkable side effect according to observation.

The invention discloses a plaster for treating bone injury, which comprises the following raw material medicines in parts by weight: 15 to 25 parts of dragon's blood, 20 to 30 parts of pangolin, 10 to 20 parts of native copper, 30 to 40 parts of mastic, 30 to 40 parts of myrrh, 25 to 35 parts of garden balsam stem, 20 to 30 parts of safflower, 30 to 40 parts of angelica, 25 to 35 parts of angelica dahurica, 20 to 30 parts of divaricate saposhnikovia root, 20 to 30 parts of gentiana macrophylla, 25 to 35 parts of rhizoma atractylodis, 20 to 30 parts of earthworm, 15 to 20 parts of clove, 20 to 30 parts of fructus cnidii and 20 to 30 parts of tuckahoe. The invention has the functions of promoting blood circulation and stopping pain, eliminating cold to remove dampness, reuniting bones and muscles, removing blood stasis and relieving swelling and the like, and is mainly used for treating closed fracture, soft tissue injury, cervical spondylosis, lumbar vertebra disease, scapulohumeral periarthritis, cold-damp rheumatic arthritis, rheumatoid arthritis, lumbar muscle and joint strain and the like.

The invention discloses a Chinese traditional medicine composite for curing urticaria and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The Chinese traditional medicine composite mainly comprises the following components in parts by weight: 20-40 parts of radix rehmanniae, 10-20 parts of angelica, 5-15 parts of radix paeoniae rubra, 5-15 parts of radix paeoniae alba, 10-20 parts of polygonum multiflorum, 5-15 parts of ephedra, 5-15 parts of radix sileris, 10-20 parts of tribulus terrestris and 5-15 parts of duckweeds. The Chinese traditional medicine composite disclosed by the invention is prepared from pure Chinese traditional medicine preparations without adding any chemical drugs by bending the drugs according to an assistant and guide principle, achieves the effect of wind dispelling enhancement by compounding principal drugs and ministerial drugs, removes the wind evil and the heat evil by blending dehumidifying and blood nourishing products for wind dispelling and heat clearing, and ensures that pruritus naturally stops through dehumidification and blood vessel smoothness. An oral solution and a pill which are prepared by the invention have the advantages of definite clinical curative effect and high cure rate and effective rate without toxic side effect after being taken for a long time, and can obviously enhance the life quality of patients; and the preparation method disclosed by the invention is simple, low in production cost and suitable for large-scale production.

An application of the extract of persimmon leaf in ethyl acetate in preparing the medicines to prevent and treat the diseases associate with glycolipid metabolism (such as hyperglycemia, diabetes, hyperlipemia, and hypertension) and metabolism syndrome is disclosed.

The invention discloses a novel Chinese traditional medicine preparation for treating hyperplasia of mammary glands and a method for preparing the same, which belongs to the technical field of Chinese traditional medicine preparations. The Chinese traditional medicine preparation is extracted from the following natural Chinese herbal medicines in portion by weight: 10 to 20 portions of radix bupleuri, 12 to 24 portions of radix paeoniae alba, 10 to 20 portions of rhizoma atractylodis macrocephalae, 12 to 24 portions of chinese angelica, 12 to 24 portions of tuckahoe, 12 to 24 portions of gardenia, 5 to 10 portions of mint, 10 to 20 portions of liquorice, and the like, wherein the materials are prepared into capsules, granules or tablets according to the prior preparation process. Clinical studies prove that the novel Chinese traditional medicine preparation has the efficacies of soothing liver and qi stagnation, softening hardness to dissipate stagnation, and regulating vital energy and invigorating blood circulation, can be applied to treating diseases of hyperplasia of mammary glands, fibroadenoma of breast, and the like, has certain effect of improving the mood of a sufferer, increasing the appetite and improving sleeping, and has no obvious untoward effects and good safety; besides, the adoption of the novel Chinese traditional medicine preparation can lighten the economic burden of sufferers.

The invention relates to a traditional Chinese medicine combination which is used for preventing the infection after oral surgery and prepared by the following raw materials according to the following weight portion: 4 portions to 12 portions of earthworm, 5 portions to 15 portions of notoginseng, 3 portions to 15 portions of radix bupleuri, 3 portions to 15 portions of Sophora flavescens, 4 portions to 12 portions of semen cuscutae, 6 portions to 9 portions of rhizoma pinelliae, 1 portion to 5 portions of nutgall, 8 portions to 10 portions of safflower, 7 portions to 10 portions of Chinese goldthread and 7 portions to 9 portions of radix clematidis. The traditional Chinese medicine combination has good treatment effect on the symptoms of nausea and the prevention of wound infection after oral surgery, no postoperative complications occur to most patients taking the medicine, and the clinical treatment effect is accurate and reliable.

The invention discloses a composition for treating oral mucositis. The composition is prepared from ropivacaine mesylate and an aluminum hydroxide and magnesium hydroxide suspension in a dose ratio of 0.5-5mg to 1ml. The invention further discloses a method for preparing the composition for treating oral mucositis. The method comprises the following steps: 1, preparing the suspension from hydroxyethyl cellulose, hydroxy propyl cellulose, simethicone, aluminum hydroxide and magnesium hydroxide; 2, adding sorbitol, mannitol and butyl p-hydroxybenzoate to regulate the pH value to obtain the aluminum hydroxide and magnesium hydroxide suspension; and 3, adding ropivacaine mesylate into the aluminum hydroxide and magnesium hydroxide suspension, and uniformly stirring to obtain the suspension for treating oral mucositis. The invention further discloses an application package for the composition for treating oral mucositis. The composition for treating oral mucositis has the advantages of relieving pain and diminishing inflammation, repairing the mucosa ulcer face and the like, and is convenient to use.

The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicine preparation for treating primary dysmenorrhea and a preparation method thereof. The traditional Chinese medicine preparation is prepared from medicinal raw materials: rhizoma cyperi, cyperus eleusinoides, Angelica sinensis, macrocarpa Nucuma, asarum caulescens maxim, rhizoma anemarrhenae and glycyrrhiza uralensis. The traditional Chinese medicine preparation has the effects of soothing liver-qi stagnation, removing blood stasis, clearing away heat and nourishing yin, and nourishing blood. The traditional Chinese medicine preparation disclosed by the invention plays a multi-target, multi-link and multi-layer comprehensive regulating effect of the traditional Chinese medicine materials aiming at multiple factors of liver depression blood-heat type dysmenorrhea, and has the effects of dredging qi and blood and naturally stopping the dysmenorrhea. Meanwhile, the traditional Chinese medicine preparation is concise in composition, precise in compatibility of medicines, exact in clinically curative effect, less in side effect, better in patient compliance, convenient to take and relatively low in recurrence rate.

The invention provides a traditional Chinese medicine composition, which is mainly composed of red rattan, scutellaria baicalensis, curcuma and Patrinia according to a certain weight ratio. A pharmaceutical preparation is prepared by adding pharmaceutically acceptable excipients, and the preparation can be in various suitable dosage forms such as capsules, granules, tablets, and powders. The pharmaceutical composition of the invention has a reasonable proportion of components, is supported by solid traditional Chinese medicine gynecology classic theories, has definite clinical curative effect, has no toxic and side effects, and is safe to take. It can be used in the preparation of medicines for treating chronic pelvic inflammatory disease. The composition of the pharmaceutical composition of the invention has less medicinal taste, easy quality control, low cost and is suitable for practical use.

The invention relates to a traditional Chinese medicine mouth chewable tablet and a preparation technology thereof, which belong to the field of pharmaceutics of Chinese medicine and clinical application. The preparation technology comprises extracting raw medicine whose weight shares are epimedy 20-40 shares, curculigo rhizome 10-20 shares, Chinese angelica 10-20 shares, cassia twig 10-15 shares, panax ginseng 10-20 shares and dried ginger 8-12 shares by water/alcohol, spraying, drying, preparing dry ointment powder, weighing, adding selective 25% filling agent, 3% adhesive, 1% correctives and 1% lubricant, evenly mixing, preparing softwood by a wet method, and compressing to be chewable tablets. Clinical test shows that the chewable tablet has the functions of warning yang, prompting qi, promoting menstruation and dispelling cold, is suitable for workers under cold environment, can reinforce cold hardiness of bodies, improves antifreezing function of limbs, and can be chewed and swallowed.

The invention belongs to the field of traditional Chinese medicine and discloses a Chinese medical preparation for treating qi-stagnation and blood stasis type primary dysmenorrheal and chloasma. The Chinese medical preparation is prepared from rhizoma cyperi, ligusticum wallichii, salviae miltiorrhizae, herba lycopi, caulis spatholobi, codonopsis convolvulacea, fructus lycii, rhizoma atractylodis macrocephalae, radix paeoniae alba, radix caulophylli, vervain and cortex albiziae. Through combination of the medicinal materials, aiming at the etiology and pathogenesis of qi-stagnation and blood stasis type primary dysmenorrheal and chloasma, the functions of soothing liver and regulating qi, promoting blood circulation to remove blood stasis, removing chloasma, regulating the chong and ren meridians, and relieving pains are realized through comprehensive communication, the multi-target, multi-link and multi-level comprehensive regulating effect is realized, side effect is mild, patient compliance is high, the medicine is easy to take, and recurrence rate is low.

The liniment for treating acute and chronic soft tissue injury caused by qi stagnation and blood stasis is prepared with Chuanxiong rhizome, safflower, angelica, frankincense, myrrh and other 12 kinds of Chinese medicinal materials in certain weight proportion. The liniment has the features of easy transdermal absorption, obvious curative effect, no adverse reaction and toxic side effect and use convenience.

The invention discloses a traditional Chinese medicine for treating wind-heat type common cold. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 30-40 parts of wild chrysanthemum flower, 12-15 parts of gynostemma pentaphyllum, 25-30 parts of pinellia ternate, 25-30 parts of selfheal, 20-25 parts of semen armeniacae amarum, 35-40 parts of radix rehmanniae, 10-15 parts of radix dipsaci, 5-8 parts of raw rhubarb, 10-15 parts of radix polygonati officinalis, 10-15 parts of radix liquiritiae, 10-12 parts of mango leaves, 20-25 parts of fermented soybeans, 5-8 parts of lalang grass rhizome, 4-5 parts of fortune eupatorium herb, 3-8 parts of mulberry leaves, 4-6 parts of fructus broussonetiae, 2-4 parts of rhizoma phragmitis, 5-10 parts of herba schizonepetae, 4-6 parts of sesame leaves, 2-4 parts of sedum aizoon, 4-5 parts of fourleaf peperomia herb and 6-10 parts of mallow root. Through combination of traditional Chinese medicines, the traditional Chinese medicines work together to reach the efficacies of clearing away heat and toxic materials, clearing dampness, bringing down a fever, inducing diuresis, resolving dampness, and expelling wind to resolve the exterior; the traditional Chinese medicine disclosed by the invention is capable of rapidly relieving the symptoms such as nasal obstruction, running nose, coughs, headaches and fevers, viscous yellow sputum, a sore throat and constipation caused by colds; and the formula is accurate in clinical curative effect, economical, practical, fast in acting, short in treatment course, free of an obvious toxic or side effect, and worthy of clinical wide application.

The invention discloses a traditional Chinese medicine for treating gynecologic bleeding and a preparation method thereof. The traditional Chinese medicine is prepared from the raw materials in parts by weight: 20-40 parts of Chinese thorowax root, 20-35 parts of hairyvein agrimony, 35-45 parts of red-rooted salvia root, 25-35 parts of paenoiae alba, 35-45 parts of Japanese peristrophe herb, 25-35 parts of cuscuta japonica choisy, 20-35 parts of calcined dragon bone, 20-30 parts of medicinal cyathula root, 20-30 parts of carbonized typhae pollen, 20-25 parts of cuttle bone, 3-8 parts of sweetening agent and 3-5 parts of additive. The traditional Chinese medicine for treating gynecologic bleeding can be used for rapidly healing gynecologic bleeding and preventing gynecologic bleeding disease, has the effects of holding blood, stopping bleeding, dispersing blood stasis, promoting generation of blood, replenishing qi and nourishing blood, and is free from side effects. By adopting the traditional Chinese medicine, pain of a patient is relieved effectively, and both symptoms and root causes are treated.

The invention relates to a pharmaceutical composition and medicine for treating hepatic injury, and a preparation method thereof. The composition is prepared from the following active pharmaceutical ingredients in parts by weight: 5-10 parts of picrorhiza rhizome, 5-10 parts of safflower, 1-5 parts of Tibetan capillaris, 1-5 parts of sophora moorcroftiana seed and 1-5 parts of myrobalam. The extracts of the active pharmaceutical ingredients and pharmaceutically acceptable assistant ingredients can form a corresponding oral preparation. The pharmaceutical composition is used for treating chemical hepatic injury, pathological hepatic injury and hepatic injury caused by many other reasons, and can have an ideal effect.

The invention provides a traditional Chinese medicine composition for treating seborrheic alopecia. The traditional Chinese medicine composition comprises paniculate swallowwort root, chloranthus spicatus, agastache, densefruit pittany root-bark, rosemary, root of hollyhock, vernonia, carthamus tinctorius, seed cowherb, ginseng leaves, sanchi flowers, semen nigellae, fructus psoraleae, black bean, peppermint camphor, borneol and kaoliang spirit. The traditional Chinese medicine composition is in the form of tincture which is formed by conducting extraction on pure traditional Chinese medicine, is fastidious and mild in formula, and simple and easy in preparation, and is mainly used for hair holding, hair regrowing, oil controlling, fat removing, acarus killing, detoxifying, dandruff removing, wind-evil dispelling and itching relieving. The tincture is high in hair regrowth efficiency and lasting in curative effect, and has the advantages that the 'ecological environment' of scalp can be improved synchronously while the purpose of hair regrowth is realized; the symptoms such as greasy scalp, too much dandruff, pruritus, epifolliculitis and seborrheic dermatitis can be treated effectively; the rebound possibilities of the symptoms are low after a user stops taking the traditional Chinese medicine composition; toxic or/and side effects are avoided; the use is safe; the traditional Chinese medicine composition can be used in preparation of medicine for treating seborrheic alopecia.

The invention provides a traditional Chinese medicine for treating dyspepsia, which comprises 10 to 20 parts of jasminum elongatum, 10 to 20 parts of herba polygoni chinensis, 20 to 30 parts of pericarpium granati, 10 to 20 parts of agastache rugosus, 15 to 25 parts of coptis chinensis, 10 to 20 parts of amomum kravanh, 15 to 25 parts of rhizoma acori graminei, 5 to 10 parts of artemisia capillaris, 15 to 25 parts of mangnolia officinalis, 5 to 10 parts of rhizoma pinellinae praeparata and 10 to 20 parts of poria cocos. The invention has the following benefical effects: the traditional Chinese medicine for treating dyspepsia remarkably improves the symptoms, such as dyspepsia, abdominal discomfort or pain, abdominal distention, heartburn (sour regurgitation), symptoms caused by central heating, unwilling to eat or eating poorly, and nightmare, and is definite and remarkable in the clinical efficacy, and takes effect quickly. The traditional Chinese medicine provided by the invention further has the advantages of being low in cost and free from toxic and side effects essentially and the like.

The invention belongs to the field of traditional Chinese medicine, and relates to a drug for treating irregular menstruation, in particular to a Chinese herbal preparation for treating abortion postoperation internal secretion normal type hypomenorrhea. The Chinese herbal preparation is elaborately prepared from radix rehmanniae praeparata, herba epimedii, angelica sinensis, codonopsis pilosula, rhizoma atractylodis macrocephalae, gorgon euryale seeds, semen cuscutae, rhizoma cyperi, radix cyathulae, stellaria yunnanensis, cyperus michelianus, salvia chinensis, pottsia laxiflora and liquorice. Through combination and interaction of different raw materials, the functions of nourishing yin and reinforcing yang, promoting blood circulation to remove blood stasis, and nourishing blood for regulating menstruation are realized. The blood flow of endometrial spiral arteries can be improved, endometrial blood perfusion can be improved, and then menstruation is improved. Furthermore, the estrogenic and progesterone hormone receptor content of the endometrium can be increased, so that menstruation is improved. Clinical research proves that the Chinese herbal preparation has obvious advantages in treating artificial abortion postoperation internal secretion normal type hypomenorrhea compared with aspirin, the curative effect is better, and adverse reaction is less.

The invention discloses a spleen-strengthening blood stasis-removing Chinese herbal compound composition which comprises, by weight parts, 10-20 parts of codonopsis pilosula Nnannf, 8-15 parts of stir-fried atractylodes, 10-20 parts of poria cocos, 10-20 parts of rhiizoma dioscoreae, 15-25 parts of raw coix seed, 8-15 parts of roasted radix aucklandiae, 3-8 parts of tangerine peel, 8-15 parts of curcuma zedoaria, 25-35 parts of salvia chinensis, 8-15 parts of roasted dark plum fruit, 10-15 parts of raw hawthorn and 2-5 parts of prepared liquorice root. The invention further discloses application of the spleen-strengthening blood stasis-removing Chinese herbal compound composition to preparation of medicines for preventing colorectal adenoma relapse. The spleen-strengthening blood stasis-removing Chinese herbal compound composition fills the blank of orally administrated medicines for clinically preventing adenoma relapse. The clinical effect is precise, the safety is good, the composition is proved according to normative clinical and trial study, and the action mechanism study is performed from the molecular level.