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Traditional Chinese medicine preparation for treating primary dysmenorrhea and preparation method thereof

A technology of traditional Chinese medicine preparations and raw materials, which is applied in the direction of medical formulas, medical preparations containing active ingredients, diseases, etc., and can solve problems such as easy drug dependence and serious human harm

Inactive Publication Date: 2016-02-03
QINGDAO MERRITT MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, the stimulation of prostaglandins can also increase the strength and frequency of uterine contraction, and the contraction is uncoordinated or non-rhythmic, resulting in uterine ischemia and hypoxia, causing dysmenorrhea. Western medicine uses drugs to treat dysmenorrhea. Commonly used drugs include ibuprofen, Ketoprofen, meclofenamic acid, diclofenac, etc. are used for the treatment of dysmenorrhea women who require contraception. Although they can relieve the symptoms of dysmenorrhea, they do great harm to the human body and are prone to drug dependence.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Prescription: 15 copies of Cyperus officinalis, 18 copies of sedge, 12 copies of Angelica sinensis, 15 copies of black blood vine, 23 copies of Wujincao, 7 copies of Anemarrhena, and 4 copies of licorice.

[0047] Preparation method: pulverize Cyperus officinalis, sedge, Angelica sinensis, black blood vine, black gold grass, Anemarrhena, licorice, add 3-8 times the amount of 35% ethanol aqueous solution, and extract twice by ultrasonic. The extraction conditions include: The ultrasonic power was 140W, the extraction temperature was 37°C, and the extraction time was 40min; after the ultrasonic extraction was completed, the filtrate was taken, concentrated under reduced pressure and dried to obtain active pharmaceutical ingredients, which were pulverized, granulated, and packed into capsule shells. Each capsule contains 0.94g of crude drug.

Embodiment 2

[0049] Prescription: 15 copies of Cyperus officinalis, 18 copies of sedge, 12 copies of Angelica sinensis, 15 copies of black blood vine, 23 copies of Wujincao, 7 copies of Anemarrhena, and 4 copies of licorice.

[0050] Preparation method: pulverize Cyperus officinalis, sedge, angelica, black blood vine, black gold grass, Anemarrhena, licorice, add 3-8 times the amount of 37% ethanol aqueous solution, extract three times by ultrasonic, and the extraction conditions include: ultrasonic The power is 150W, the extraction temperature is 35°C, and the extraction time is 30min; after the ultrasonic extraction is completed, the filtrate is taken, concentrated under reduced pressure and dried to obtain active pharmaceutical ingredients, which are pulverized, granulated, and packed into capsule shells.

Embodiment 3

[0052] Prescription: 15 copies of Cyperus officinalis, 18 copies of sedge, 12 copies of Angelica sinensis, 15 copies of black blood vine, 23 copies of Wujincao, 7 copies of Anemarrhena, and 4 copies of licorice.

[0053] Preparation method: pulverize Cyperus officinalis, sedge, angelica, black blood vine, black gold grass, nemesis, licorice, add 3-8 times the amount of 40% ethanol aqueous solution, extract three times by ultrasonic, and the extraction conditions include: ultrasonic The power is 130W, the extraction temperature is 35°C, and the extraction time is 30min; after the ultrasonic extraction is completed, the filtrate is taken, concentrated under reduced pressure and dried to obtain active pharmaceutical ingredients, which are pulverized, granulated, and packed into capsule shells.

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicine preparation for treating primary dysmenorrhea and a preparation method thereof. The traditional Chinese medicine preparation is prepared from medicinal raw materials: rhizoma cyperi, cyperus eleusinoides, Angelica sinensis, macrocarpa Nucuma, asarum caulescens maxim, rhizoma anemarrhenae and glycyrrhiza uralensis. The traditional Chinese medicine preparation has the effects of soothing liver-qi stagnation, removing blood stasis, clearing away heat and nourishing yin, and nourishing blood. The traditional Chinese medicine preparation disclosed by the invention plays a multi-target, multi-link and multi-layer comprehensive regulating effect of the traditional Chinese medicine materials aiming at multiple factors of liver depression blood-heat type dysmenorrhea, and has the effects of dredging qi and blood and naturally stopping the dysmenorrhea. Meanwhile, the traditional Chinese medicine preparation is concise in composition, precise in compatibility of medicines, exact in clinically curative effect, less in side effect, better in patient compliance, convenient to take and relatively low in recurrence rate.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine preparation for treating primary dysmenorrhea and a preparation method thereof. Background technique [0002] Dysmenorrhea is one of the most common diseases in gynecology, and its incidence varies from 42% to 90%, among which severe dysmenorrhea accounts for about 18%. In severe cases, it may be accompanied by nausea and vomiting, cold sweat, cold hands and feet, and even syncope. , which affects life and work, and is detrimental to women's physical and mental health. [0003] Western medicine obstetrics and gynecology divide dysmenorrhea into primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea, also known as functional dysmenorrhea, refers to those without organic lesions in the reproductive organs. It is believed that its occurrence is related to the increased synthesis and release of prostaglandins in th...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P15/00
Inventor 吴兴连
Owner QINGDAO MERRITT MEDICAL TECH CO LTD
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