The invention discloses a ginseng and solomonseal rhizome paste. The ginseng and solomonseal rhizome paste is composed of the following raw materials: ginseng, solomonseal rhizome, common yam rhizome,gordon euryale seed, inner membrane of chicken gizzard, Indian bread, dried tangerine peel, liquorice root, fried lentils, germinated barley, parched hawthorn fruit, seabuckthorn fruit, villous amomum fruit, radish seed, dandelion, fragrant solomonseal rhizome, finger citron, lily bulb, English walnut seed, black sesame, ass hide glue, honey and yellow rice wine. The invention further discloses apreparation method of the ginseng and solomonseal rhizome paste. The components in the formula are rigorous in compatibility, simple in medicine taking, moderate in reinforcing and reducing, and mildin medicine property, and all the components complement each other, and jointly exert the effect of invigorating stomach and nourishing stomach, wherein common yam rhizome, Indian bread and ginseng have the effects of invigorating spleen and tonifying qi, gordon euryale seed has the effects of transforming qi, promoting diuresis and drying dampness, inner membrane of chicken gizzard, germinated barley and hawthorn fruit contain digestive enzyme, seabuckthorn fruit has the effects of invigorating spleen, nourishing stomach, helping digestion, and promoting blood circulation for removing bloodstasis, the components are used in cooperation, the purpose of nourishing stomach and regulating spleen and stomach can be achieved, the rehabilitation of stomach diseases is promoted, and thereby relatively obvious effects on the recovery, prevention and relapse of stomach diseases are achieved.