Meridian warming patch for treating dysphagia after cerebral apoplexy and preparation method thereof

Abstract

The invention discloses a collateral-warming patch for treating dysphagia after stroke and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine formulae, the collateral-warming patch is composed of 20 parts of pinellia ternate, 10 parts of magnolia officinalis, 10 parts of puffball, 10 parts of blackberry lily, 5 parts of dragon's blood, 5 parts of cassia twig, 5 parts of stiff silkworm, 2 parts of clove and 2 parts of menthol. The preparation method comprises the following steps: step 1, respectively grinding the traditional Chinese medicine components in the collateral-warming patch into powder, and sieving with a 100-mesh sieve; step 2, uniformly mixing the traditional Chinese medicine powder according to a ratio, adding honey and water, heating for 5 minutes in a microwave oven with high fire, pouring the ginger juice, and uniformly stirring to prepare paste; and step 3, injecting the pasty medicine into a plastic bottle by using an injector, pasting a label, and refrigerating. Based on traditional Chinese medicine and external application therapy, gastrointestinal tract adverse reaction possibly caused by oral administration of medicine is avoided, and the traditional Chinese medicine is suitable for patients of all ages.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine formulas, and particularly relates to a Wenluo patch for treating post-stroke dysphagia and a preparation method thereof. Background Art

[0002] The threat of stroke to human health is growing year by year. The number of cases is on the rise, and the recurrence rate is high. The number of disabilities and deaths caused by stroke is also gradually increasing, causing a serious economic burden on society and bringing emotional trauma to families that cannot be ignored.

[0003] Stroke can lead to a series of complications, among which 14% to 31% of patients have cognitive impairment combined with dysphagia. Such patients often experience difficulty opening their mouths, chewing with difficulty, tongue movement disorders, food staying in the mouth for too long, drooling, and coughing. As stroke patients age, the risk of adverse outcomes gradually increases. If not properly managed, it can lead to complications such as inability to take care of themselves, suffocation, or loss of consciousness. In order to improve dysphagia caused by stroke, it is necessary to effectively prevent complications and improve prognosis.

[0004] Studies have shown that icy acid stimulation can promote basic rehabilitation training for the recovery of swallowing function in patients. It can improve swallowing function by stimulating the tongue and pharynx of patients, increase patients' perception of food and attention to eating and swallowing, and excite the swallowing-related cortex.

[0005] Traditional Chinese medicine believes that dysphagia is not a single disease, but a symptom associated with many diseases. Clinically, it can be divided into functional and organic dysphagia. Functional dysphagia is more common in "stroke", while organic dysphagia is more common in "hiccups", "tongue paresthesia" and "throat paralysis". Chinese medicine has various treatments for dysphagia after stroke. External application therapy is a treatment method guided by the basic theory of Chinese medicine and applied to the skin, acupoints and local lesions. It is an important part of Chinese medicine treatment and has the characteristics of "simple, convenient, effective and cheap". External application therapy provides a new treatment method for some patients who are afraid of needles and have poor oral compliance. It can directly reach the meridians and internal organs through skin penetration. In addition, Chinese medicine patching can increase the contact time between the drug and the skin, so that the drug continues to act on the body, which effectively guarantees the continuous and stable treatment effect. The use of traditional Chinese medicine to treat dysphagia after stroke can often achieve certain results, but the long-term effect is still not ideal, and there is a lack of clinically effective ideas for the use of combined therapies. Although there have been some research reports on combined therapies in recent years, there is still a lack of new ideas and methods for combined treatments of traditional Chinese medicine in clinical practice. Summary of the invention

[0006] In view of the deficiencies in the prior art, the purpose of the present invention is to provide a Wenluo patch for treating post-stroke dysphagia and a preparation method thereof. Wenluo patch combined with glacial acid stimulation is applied to the rehabilitation training of patients with dysphagia under the guidance of traditional Chinese medicine theory. Wenluo patch combined with glacial acid stimulation has high safety. Based on traditional Chinese medicine and external application therapy, it avoids the gastrointestinal adverse reactions that may be caused by oral medication and is suitable for patients of all ages. At the same time, the external application method of Wenluo patch is simple and easy, which improves the patient's treatment compliance and comfort.

[0007] The technical solution of the present invention is as follows:

[0008] In a first aspect, the present invention provides a Wenluo patch for treating post-stroke dysphagia, the Wenluo patch comprising Pinellia, Magnolia officinalis, Puffball, Belamcanda chinensis, Sanguisorba officinalis, Cinnamomum cassia, Bombyx batryticatus, Clove, and menthol.

[0009] In some embodiments, the Chinese medicinal ingredients in the Wenluo patch are counted according to the following weight parts: 18-22 parts of Pinellia, 8-12 parts of Magnolia officinalis, 8-12 parts of Puffball, 8-12 parts of Belamcanda, 4-6 parts of Sanguisorba officinalis, 4-6 parts of Cinnamon Twig, 4-6 parts of Bombyx Batryticatus, 1-3 parts of Clove 、 1-3 parts of menthol.

[0010] In some embodiments, the Chinese medicinal ingredients in Wenluo patch are counted according to the following weight parts: 20 parts of Pinellia, 10 parts of Magnolia officinalis, 10 parts of Puffball, 10 parts of Belamcanda chinensis, 5 parts of Sanguisorba officinalis, 5 parts of Cinnamon twig, 5 parts of Bombyx batryticatus, 2 parts of Cloves, and 2 parts of Menthol.

[0011] In a second aspect, the present invention provides a method for preparing a Wenluo patch for treating post-stroke dysphagia, the preparation method comprising the following steps:

[0012] Step 1: Grind each Chinese medicine ingredient in the Wenluo patch into powder and pass through a 100-mesh sieve;

[0013] Step 2: Weigh the dosage of each Chinese medicine powder separately, mix well, add 60g honey and 100ml water, heat in a microwave oven on high heat for 5 minutes, add 30ml ginger juice, stir well, and make into a paste;

[0014] Step 3: Use a syringe to pour the paste into a plastic bottle, label it, and refrigerate it.

[0015] Compared with the prior art, the present invention has the following advantages:

[0016] 1. The prescription and medicine are strictly compatible. The prescription and medicine are strictly compatible. The Wenluo patch of the present invention is based on Banxia Houpu Decoction and is added with puffball and Belamcanda chinensis as throat-relieving drugs, Xuejie as blood-activating and stasis-removing drug, cinnamon twig as wind-dispelling and anti-spasmodic drug, and clove and menthol as penetration-promoting drugs. In this prescription, Pinellia and Magnolia officinalis are the main drugs, which mainly play the role of resolving phlegm, opening the orifices, promoting qi and reducing adverse reactions, and clearing the throat. Both of them are the main drugs, which greatly enhance the effect of reducing adverse reactions and resolving phlegm; Puffball and Belamcanda are the assistant drugs, which have the effects of clearing away heat and detoxifying, eliminating phlegm, and relieving sore throat; and are supplemented with Blood Dracaena, Bombyx Batryticatus, and Cinnamon Twig. Blood Dracaena has the effect of promoting blood circulation and removing blood stasis, Bombyx Batryticatus has the effect of calming wind and relieving spasm, dispelling wind and relieving pain, and resolving phlegm and dispersing nodules. Cinnamon Twig has the effect of warming and unblocking meridians, assisting yang and transforming qi, and can enhance the effect of reducing adverse reactions, resolving phlegm, and dispersing nodules when combined with the main drugs; Menthol and Clove are the assistant drugs. Menthol has the effect of dispelling wind and clearing heat, relieving sore throat and rash, and can relieve sore throat and prevent skin allergies caused by external application drugs. Combined with the clove oil in clove, it can effectively enhance the penetration of drugs into the skin and promote absorption. The whole prescription has the effects of resolving phlegm, opening the orifices, clearing the throat, and removing blood stasis and unblocking the meridians.

[0017] 2. The clinical efficacy is definite. After the treatment with Wenluo patch combined with icy acid stimulation, the patient's Kubota drinking test grade and swallowing function are significantly improved, and the TCM symptom score also shows a positive trend. In addition, the patient's satisfaction with the treatment has increased, reflecting the potential of the therapy in improving the quality of life. The Chinese medicine formula is selected from common and effective Chinese medicinal materials, which are easy to obtain and have low production costs, and are "simple, convenient, effective, and cheap". DETAILED DESCRIPTION

[0018] In the description of the present invention, it should be noted that, if the specific conditions are not specified in the examples, the experiments were carried out according to conventional conditions or the conditions recommended by the manufacturer. The reagents or instruments used, if the manufacturer is not specified, are all conventional products that can be purchased commercially.

[0019] The present invention is further described below in conjunction with specific embodiments.

[0020] "Ice and fire therapy, reconstruction of yin and yang" is based on the principles of "where medicine is inadequate and needles cannot reach, fire can cure it" and "where the meridians pass, the main treatment can reach it", and refers to the rehabilitation concept of "combining systemic treatment with local treatment, macro rehabilitation with micro rehabilitation". A new therapy for post-stroke dysphagia was invented, which can accelerate the reconstruction of swallowing-related functions, achieve the purpose of dredging meridians, eliminating phlegm and blood stasis, orderly ascending and descending, balancing yin and yang, and clearing the channels and opening the orifices. It embodies the scientific nature of the "ice and fire therapy, reconstruction of yin and yang" treatment of post-stroke dysphagia.

[0021] "Ice and Fire Therapy" refers to the application of ice-acid stimulation combined with warm-luo patch in patients with swallowing dysfunction. Ice-acid stimulation combined with warm-luo patch therapy is implemented on the basis of routine nursing. Ice-acid stimulation is to conduct ice-acid stimulation rehabilitation training for patients at regular times and locations, 15 minutes / time, for 2 consecutive weeks. The acupoints for warm-luo patch are Renying, Tiantu, Lianquan, Zusanli, and Sanyinjiao.

[0022] This embodiment specifically provides a Wenluo patch for treating post-stroke dysphagia, which is composed of 18-22 parts of Pinellia, 8-12 parts of Magnolia officinalis, 8-12 parts of Puffball, 8-12 parts of Belamcanda, 4-6 parts of Sanguisorba officinalis, 4-6 parts of Cinnamon twig, 4-6 parts of Bombyx batryticatus, and 1-3 parts of Clove. 、 Composition: 1-3 parts of menthol.

[0023] Example 1

[0024] Prescription of this embodiment: 20g of Pinellia, 10g of Magnolia officinalis, 10g of Puffball, 10g of Belamcanda, 5g of Sanguisorba officinalis, 5g of Cinnamon Twig, 5g of Bombyx Batryticatus, 2g of Clove 、 Menthol 2g.

[0025] The method for preparing the Wenluo patch according to the above prescription comprises the following steps:

[0026] Step 1: Grind each Chinese medicine ingredient in the Wenluo patch into fine powder and pass through a 100-mesh sieve;

[0027] Step 2: Weigh the dosage of each Chinese medicine powder separately, mix well, add 60g honey and 100ml water, heat in a microwave oven on high heat for 5 minutes, add 30ml ginger juice, stir well, and make into a paste;

[0028] Step 3: Use a syringe to pour the paste into a plastic bottle, label it, and refrigerate it.

[0029] When using, spread the above ointment evenly on the dressing patch, and stick it on the Renying, Tiantu, Lianquan, Sanyinjiao, and Zusanli acupoints.

[0030] The specific process of conducting clinical trials using the above specific formula is as follows:

[0031] 1. Research subjects and diagnostic criteria

[0032] 1.1 Research subjects

[0033] A total of 60 patients with post-stroke dysphagia admitted to our hospital from December 2023 to May 2024 were selected as research subjects.

[0034] 1.2 Diagnostic criteria

[0035] 1.2.1 Western medicine diagnostic criteria: The diagnostic criteria for dysphagia refer to the "Diagnostic criteria for various cerebrovascular diseases" formulated by the Chinese Medical Association's Cerebrovascular Disease Academic Conference and are confirmed by head CT or magnetic resonance imaging (MRI). Screening with the "Standard Swallowing Assessment Scale (SSA)" indicates that there is dysphagia.

[0036] At the same time, the following symptoms may be present: ① pronunciation and language disorders, difficulty chewing and swallowing, and coughing when drinking water. ② Movement disorders of the soft palate, pharyngeal muscles, tongue muscles, masseter muscles, or facial muscles, but without tongue muscle atrophy and fasciculations. ③ The pharyngeal reflex exists, or is weakened or absent, the soft palate reflex is weakened or absent, the mandibular reflex is hyperactive, and the pathological brainstem reflex is positive. ④ Pyramidal tract signs (paralysis of one or both limbs) or emotional disorders (indifferent expression, dementia, or forced crying or laughing). ⑤ Or two of the above main symptoms are present and combined with dysphagia.

[0037] 1.2.2 TCM diagnostic standards: The “Standards for Diagnosis and Therapeutic Effect Evaluation of Stroke” formulated by the Encephalopathy Emergency Research Collaboration Group of the State Administration of Traditional Chinese Medicine shall be adopted.

[0038] Main symptoms: hemiplegia, slurred speech or aphasia, paresthesia of one side, crooked mouth and tongue;

[0039] Secondary symptoms: headache, dizziness, pupil changes, choking when drinking water, unblinking eyes, and ataxia.

[0040] Acute onset, often with triggers and prodromal symptoms before the onset; the age of onset is mostly over 40 years old, with two or more main symptoms, or one main symptom and two secondary symptoms, and the diagnosis can be made by combining the onset, triggers, prodromal symptoms, and age; if the above conditions are not met, the diagnosis can also be made by combining the results of imaging examinations.

[0041] 2. Inclusion and exclusion standards

[0042] 2.1 Inclusion criteria

[0043] (1) Those with infarction lesions shown by magnetic resonance imaging (MRI) or computed tomography (CT) and confirmed as dysphagia by the Kubota water drinking test;

[0044] (2) Those who are conscious;

[0045] (3) Approved by the Medical Ethics Committee, and the patients were informed and voluntarily participated in this study.

[0046] 2.2 Exclusion criteria

[0047] (1) Patients with severe illness;

[0048] (2) Those with swallowing dysfunction caused by other diseases;

[0049] (3) Patients with intracranial hemorrhage or other lesions or combined brain tumors excluded by MRI or CT;

[0050] (4) Patients with hematopoietic system diseases;

[0051] (5) Patients with severe organic lesions in organs such as the heart, liver, and kidney;

[0052] (6) Patients with other stroke sequelae.

[0053] 3. Treatment Methods

[0054] 3.1 Ice acid stimulation

[0055] When the patients are in the best condition, that is, at three time zones every day (10:00, 16:00, and 20:00), ice acid stimulation rehabilitation training is performed on the patients at regular times and locations, 20 minutes per time, twice a day, for two consecutive weeks.

[0056] The specific method of ice acid stimulation rehabilitation training is: dip a wet cotton swab into acidic substances such as vinegar, lemon juice, VC powder, acid enzyme powder, etc., and freeze them in the refrigerator to make acid popsicles. Choose a quiet and comfortable environment. After routine oral care, assist the patient to take a 30° supine position, and use acid popsicles to gently stimulate the patient's tongue root, palatopharyngeal arch, posterior pharyngeal wall and other swallowing reflex sites. At the same time, ask the patient to do empty swallowing, alternating swallowing, lateral swallowing, nodding swallowing and other actions, and use acid popsicles to gently massage the tongue body, guide the patient's tongue muscle and chewing muscle movement, and the training time is 20 minutes each time, 2 times / d. During the ice acid stimulation intervention, if the patient has nausea, vomiting, choking, aspiration, etc., stop in time.

[0057] 3.2 Preparation and acupoint selection of Wenluo patch

[0058] Preparation of Wenluo patch: 20g of Pinellia, 10g of Magnolia officinalis, 10g of Puffball, 10g of Belamcanda, 5g of Sanguisorba officinalis, 5g of Cinnamon twig, 5g of Bombyx batryticatus, 2g of Clove 、 Menthol 2g.

[0059] Accessories: honey, ginger juice

[0060] Preparation method: Grind the above medicines into powder separately, pass through a 100-mesh sieve, mix evenly according to the proportion, add honey and water, stir evenly, heat on high heat in a microwave for 5 minutes, then pour in ginger juice to make a paste, inject into a plastic bottle with a syringe, label it, and refrigerate.

[0061] Acupoints: The acupoints for warming the meridians are Renying, Tiantu, Lianquan, Sanyinjiao and Zusanli.

[0062] 4. Grouping and intervention

[0063] The patients were divided into two groups by random number table method, 30 cases in each group. The control group received conventional treatment and rehabilitation nursing. The observation group received ice acid stimulation combined with warming patch therapy on the basis of the nursing of the control group. Conventional rehabilitation nursing training: Both groups received treatments such as promoting brain circulation metabolism and brain protection, and combined with conventional rehabilitation training such as acupuncture, food intake training, and pronunciation training.

[0064] 5. Effect evaluation

[0065] 5.1 Observation indicators:

[0066] (1) Swallowing ability assessment: The Kubota drinking test was used. The patient was asked to drink 30 mL of 37-40°C warm water at a normal speed and observe the choking and time. If the water was drunk in one go within 5 seconds without choking, it was grade I; if the water was drunk in two or more times within 5-10 seconds without choking, it was grade II; if the water was swallowed in one go within 5-10 seconds but with choking, it was grade III; if the water was drunk in two or more times within 5-10 seconds with choking, it was grade IV; if the water could not be drunk in 10 seconds with obvious choking, it was grade V.

[0067] ① Cured: The symptoms of dysphagia basically disappeared, and the drinking test was rated as Grade I;

[0068] ②Effective: The symptoms of dysphagia were significantly improved, and the drinking test was rated as Grade II;

[0069] ③ Ineffective: Swallowing disorder did not improve significantly, and the water drinking test was assessed as Grade III or above.

[0070] (2) Swallowing disorder evaluation criteria: Standardized Swallowing Assessment (SSA), which is divided into 0 to 10 points, with 10 points indicating normal swallowing and lower scores indicating more severe dysphagia. The scale includes the selection of rehabilitation training methods, using nutritional intake as a clue, and reflects the ability to eat orally.

[0071] The specific contents are as follows:

[0072] 1 point means unsuitable for any swallowing and unable to eat orally; 2 points means only suitable for basic swallowing training and unable to eat orally; 3 points means able to undergo feeding training but unable to eat orally; 4 points means able to eat a small amount of food during comfort but requires intravenous nutrition; 5 points means able to eat 1 to 2 kinds of food orally and requires partial intravenous nutrition; 6 points means able to eat 3 kinds of food orally and requires partial intravenous nutrition; 7 points means able to eat 3 kinds of food orally and does not require intravenous nutrition; 8 points means able to eat orally except for foods that are particularly difficult to swallow; 9 points means able to eat orally but requires clinical observation; 10 points means normal feeding and swallowing abilities.

[0073] (3) Post-stroke symptom evaluation score scale: refer to the "Stroke Syndrome Diagnostic Standard" formulated by the National Administration of Traditional Chinese Medicine's Brain Disease Emergency Research Collaboration Group for scoring observation, 0-7 points for mild; 7-14 points for moderate; 14-21 points for severe. The scores of the treatment group and the control group were compared based on the improvement of symptoms such as dizziness, lip color, and insomnia before and after treatment.

[0074] (4) Nursing satisfaction: The patient satisfaction questionnaire (CSQ-8) was issued on the day of discharge to evaluate nursing satisfaction. There are 8 questions with a total score of 32 points, which are divided into 4 levels: very satisfied (more than 24 points), satisfied (17-24 points), average (9-16 points), and dissatisfied (≤8 points). 17 points or above are considered satisfied.

[0075] 6. Statistical methods SPSS24.0 software was used for statistical analysis of the data. The measurement data were tested with t value, and the counting data were tested with x±s test. P < 0.05 was considered statistically significant.

[0076] 7. Results

[0077] 7.1 Comparison of clinical efficacy

[0078] The total effective rate of the observation group was 90.0%, and the total effective rate of the control group was 76.7%. The total effective rate of the observation group was higher than that of the control group, P<0.05, and the difference was statistically significant, indicating that the observation group had a higher therapeutic effect than that of the control group (see Table 1).

[0079] Table 1 Comparison of efficacy between the two groups

[0080]

[0081] 7.2 Comparison of swallowing function rating and SSA score

[0082] There was no significant difference in the swallowing function rating and dysphagia score between the two groups before the intervention (P>0.05). After the intervention, the swallowing function rating and dysphagia score of the treatment group were lower than those of the control group, and the difference was statistically significant (P<0.05) (see Table 2).

[0083] Table 2 Comparison of swallowing function rating and swallowing disorder score between the two groups before and after intervention (x±s, points, n=30)

[0084]

[0085] 7.3 Post-stroke symptom assessment score

[0086] After the intervention, the TCM symptom scores of both groups decreased, and the improvement effect of the observation group was better than that of the control group. The difference was statistically significant at P < 0.05 (see Table 3).

[0087] Table 3 TCM symptom scores of the two groups before and after the intervention

[0088]

[0089]

[0090] Table 4 Registration form of patients with swallowing dysfunction (control group)

[0091]

[0092]

[0093] Table 5 Registration form of patients with swallowing dysfunction (observation group)

[0094]

[0095]

[0096] The results of this study showed that the swallowing function, symptom improvement, effectiveness and satisfaction of the observation group using Wenluo patch acupoint application were significantly better than those of the control group, indicating that the Wenluo patch acupoint application used in this study to treat dysphagia caused by stroke can effectively improve swallowing function and has obvious advantages of traditional Chinese medicine. This therapy uses drugs to stimulate specific meridians and acupoints, and directly reaches the meridians and internal organs through skin penetration. Drug acupoint application effectively increases the contact time between drugs and skin, allowing the drugs to continue to act on the body, causing local blood vessels to dilate and blood circulation to accelerate. At the same time, the drugs penetrate the skin and pores from the surface to the inside, and through the meridians, they connect the internal organs, communicate the surface and the inside, and exert their efficacy, avoiding the hepato-renal toxicity of oral drugs. The operation is simple, safe and effective, and worthy of clinical promotion.

[0097] Typical Cases

[0098] 1. Basic information of the patient

[0099] Name: Huang Moumou; Gender: Male; Age: 76 years old; Hospitalization number: 511769; Type of hospitalization expense: social security; Disease diagnosis: cerebral infarction; Admission date: September 22, 2023; Past history: hypertension, type 2 diabetes; Allergy history: none; Discharge date: November 16, 2023.

[0100] 2. Case presentation

[0101] Medical history

[0102] Chief complaint: Admitted to hospital on 09-22 due to sudden slurred speech and left limb weakness for more than 5 hours.

[0103] Current medical history: The patient suddenly developed slurred speech without obvious cause before about 12:00 on 09-22, accompanied by left-side limb weakness, inability to lift left limbs, accompanied by dizziness, nausea, and vomiting, no limb convulsions, no limb numbness, and good right limb movement. He went to Boluo County People's Hospital for treatment. A head CT scan showed no cerebral hemorrhage. He was given intravenous alteplase for thrombolysis. His symptoms improved after thrombolysis. A head CTA scan showed basilar artery occlusion. For further diagnosis and treatment, his family members sent him to our hospital for treatment. When he was admitted to the hospital, he could lift his left limbs, but could not speak, and had difficulty lifting his right limbs.

[0104] Auxiliary examination:

[0105] 9-22: Head CT: 1. Brain infarction in the pons and bilateral cerebellar hemispheres. 2. Brain atrophy. 3. Bilateral internal carotid artery sclerosis. Chest CT: 1. Bilateral lung infection, differentiated from neurogenic pulmonary edema, please combine clinical diagnosis for further diagnosis; 2. A small amount of pleural effusion in both sides.

[0106] 9-26: Head CT: 1. Post-treatment review of pons and bilateral cerebellar hemisphere cerebral infarction is as above, please combine with clinical findings. 2. Brain atrophy. 3. Bilateral internal carotid artery sclerosis.

[0107] 9-30: Plain CT scan of the head: 1. Post-treatment review of pons and bilateral cerebellar hemisphere cerebral infarction is as above, please combine with clinical findings. 2. Brain atrophy. 3. Bilateral internal carotid artery sclerosis.

[0108] Chest spiral CT scan: 1. Compared with the previous film, the number of lesions in both lungs is more than before, please combine clinical diagnosis for further diagnosis; 2. The number of small bilateral pleural effusions is more than before;

[0109] 10-24: Chest CT: 1. Compared with the previous film, the lesions in both lungs are slightly reduced, and the consolidation range in the posterior segment of the right upper lobe and the posterior basal segment of the lower lobe is smaller than before.

[0110] 2.2 Treatment

[0111] The treatment process is not related to this plan and will not be introduced in detail.

[0112] 3. Postoperative Care

[0113] 3.1 Ice acid stimulation: According to the patient's individuality, the best two time periods are selected for the rehabilitation training of ice acid stimulation, 20 minutes / time for 2 consecutive weeks. The specific method of ice acid stimulation rehabilitation training: lemon juice and other acidic substances are placed in the refrigerator to make acid popsicles. Assist the patient to take a 30° supine position. After routine oral care, use the acid popsicle to gently stimulate the patient's palatopharyngeal arch and other swallowing reflex parts. At the same time, ask the patient to do empty swallowing and other actions, and guide the patient's tongue muscle and chewing muscle movement. The training time is 20 minutes each time, 2 times / day.

[0114] 3.2 Wenluo plaster acupoints are Renying, Tiantu, Lianquan, Zusanli, Sanyinjiao. The formula is composed of 20g of Pinellia, 10g of Magnolia officinalis, 10g of Puffball, 10g of Belamcanda, 5g of Sanguisorba officinalis, 5g of Cinnamon Twig, 5g of Bombyx Batryticatus, and 2g of Clove. 、 The above drugs are powdered separately, passed through a 100-mesh sieve, mixed evenly according to the proportion, added with honey and water, stirred evenly, and then poured into ginger juice to make a paste, injected into a plastic bottle with a syringe, labeled, and refrigerated.

[0115] Apply for 4 hours each time, 2 times / day, for 2 weeks. The operation schedule is as follows

[0116]

[0117] 4. Effect evaluation

[0118] 4.1 Nursing effectiveness

[0119] (1) Summary of Specialty Assessment Project

[0120] project On admission When discharged from hospital ADL score 10 points 25 points NRS2002 Nutrition Screening 4 points 3 points Padua Risk Assessment Scale 4 points 2 points NIHSS score 12 points 12 points Falling from bed and falling risk assessment 75 points 60 points Braden Pressure Ulcer Risk Assessment 11 points 14 points

[0121] (2) Summary of nursing outcomes

[0122]

[0123] Through the above clinical comparison, it was found that after the treatment of the present invention using the Wenluo patch combined with icy acid stimulation, the patient's Kubota drinking test grade and swallowing function were significantly improved, and the TCM symptom score also showed a positive trend. In addition, the patient's satisfaction with the treatment increased, reflecting the potential of the therapy in improving the quality of life. The Chinese medicine formula is selected from common and effective Chinese medicinal materials, which are easy to obtain and have low production costs, and have the characteristics of "simple, convenient, effective and cheap".

Claims

1. A Wenluo patch for treating post-stroke dysphagia, characterized in that: The warming patch includes pinellia, magnolia bark, puffball, iris, blood clotting, cinnamon twig, bombyx batryticatus, clove and menthol.

2. A Wenluo patch for treating post-stroke dysphagia according to claim 1, characterized in that The Chinese medicinal ingredients in Wenluo Patch are counted according to the following weight parts: 18-22 parts of Pinellia, 8-12 parts of Magnolia officinalis, 8-12 parts of Puffball, 8-12 parts of Belamcanda, 4-6 parts of Sanguisorba officinalis, 4-6 parts of Cinnamon Twig, 4-6 parts of Bombyx Batryticatus, 1-3 parts of Clove 、 1-3 parts of menthol.

3. The Wenluo patch for treating post-stroke dysphagia according to claim 2, characterized in that: The Chinese medicinal ingredients in Wenluo Patch are counted according to the following weight parts: 20 parts of Pinellia, 10 parts of Magnolia officinalis, 10 parts of Puffball, 10 parts of Belamcanda chinensis, 5 parts of Sanguisorba officinalis, 5 parts of Cinnamon Twig, 5 parts of Bombyx Batryticatus, 2 parts of Cloves, and 2 parts of Menthol.

4. A method for preparing a Wenluo patch for treating post-stroke dysphagia according to any one of claims 1 to 3, characterized in that: The preparation method comprises the following steps: Step 1: Grind each Chinese medicine ingredient in the Wenluo patch into powder and pass through a 100-mesh sieve; Step 2: Weigh the dosage of each Chinese medicine powder separately, mix them evenly, add honey and water, heat them in a microwave oven on high heat for 5 minutes, add ginger juice, stir evenly, and make a paste; Step 3: Use a syringe to pour the paste into a plastic bottle, label it, and refrigerate it.

5. The Wenluo patch for treating post-stroke dysphagia according to claim 4, characterized in that: In step 3, the amount of honey added is 60g, and the amount of water added is 100ml.

6. The Wenluo patch for treating post-stroke dysphagia according to claim 4, characterized in that: The amount of ginger juice added in step 2 is 30ml.

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