The present invention relates to a mixture of medicinal powder and activated carbon and the preparation method thereof, which pertains to the traditional Chinese medicine products; the formula of the mixture is composed of 80 traditional Chinese medicine ingredients of abrus herb, shinyleaf pricklyash root, Chinese arborvitae twig, winged euonymus twig, ovientvine, buerger pipewort flower, radix ranunculi ternati etc. and maifanite, germanite and crystal minerals, and the mixture is prepared by smashing, mixing, water soaking, boiling, filtering, drying, carbonization, activation, rubber refining, redrying and smashing processes; the mixture has good effects of health care for the human body, treatment and prevention of the diseases, furthermore, the functions are extensive, the cost of the product is low, the usage is convenient, the application scope is wide, the preparation method is simple and the operations are easy to control.