The invention relates to a methanol fuel additive for cold plateau region. The additive is prepped by adding 3-20 wt.% of an oxidant hydrogen peroxide with mass concentration of 30%, 1-6% of an antifreeze, 0.2-3% of an antioxidant antigum agent 2,6-butylated hydroxytoluene, 0.05-0.6% of a metal passivator N,N-bis(salicylidene)-1,2-propanediamine, 0.008-0.06% of a detergent dispersant, 1-6% of a preservative and 1-20% of a emulsifier into 10-83.742% of aqueous solution, mixing evenly by pump circulation, then successively adding 3-20% of naphtha, 3-10% of toluene, 2-10% of xylene, 2-10% of C5H12-C7H16 in weight ratio of 1:1, and mixing homogeneously by pump circulation. At the same time, the invention also discloses a ratio and a preparation method of a methanol fuel containing the methanol fuel additive for cold plateau region. The methanol fuel additive for cold plateau region provided by the invention has good and stable performance, and solves the problems of low temperature fluidity, high altitude hypoxia burning property, low sulfur, low nitrogen and dynamic stability.