The invention discloses a medicine for treating ascites due to liver cancer. The medicine comprises the following components in parts by weight: 15-19 parts of radix bupleuri, 15-19 parts of bighead atractylodes rhizome, 20-24 parts of white peony root, 15-19 parts of dried tangerine peel, 10-14 parts of chrysanthemum morifolium, 10-14 parts of Chinese angelica, 15-19 parts of salviae miltiorrhizae, 20-24 pats of fiveleaf akebia fruit, 5-9 parts of safflower, 15-19 parts of poria, 20-24 parts of sculellaria barbata, 20-24 parts of rhizoma sparganic, 30-34 parts of polygonum cuspidatum, 10-14 parts of moutan bark, 20-24 parts of dandelion, 20-24 parts of solanum nigrum, 20-24 parts of oriental wormwood, 20-24 parts of curcuma zedoary, 20-24 parts of aspongopus, 20-24 parts of indian iphigenia bulb, 10-14 parts of spina gleditsiae, 20-24 parts of manyleaf paris rhizome, 10-14 parts of fructus aurantii, 15-19 parts of artemisia anomala, 20-24 parts of raw oyster, 20-24 parts of turtle shell, 10-14 parts of costustoot, 15-19 parts of codonopsis pilosula, 30-34 parts of selfheal, 15-19 parts of salvia chinensis, 15-19 parts of verbena, 5-9 parts of rhizoma alismatis, 5-9 parts of polyporus umbellatus, 10-14 parts of plantain seed, 10-14 parts of frankincense, 10-14 parts of myrrh, 10-14 parts of corydalis tuber, 10-14 parts of radix curcumae, 10-14 parts of toad skin, 5-9 parts of greater celandine herb, 5-9 parts of szechwan Chinaberry fruit, 10-14 parts of sappanwood, 3-7 parts of radix phytolaccae, 10-14 parts of paniculate swallowwort root, and 3-7 parts of semen pharbitidis. The effective rate of the medicine in treating ascites due to liver cancer can be 73 percent.