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Anti-tumor medicament composition

A composition and anti-tumor technology, applied in the field of medicine, can solve problems such as obvious toxic and side effects, affect the quality of life of patients, and unsatisfactory overall curative effect, and achieve the effect of easy-to-obtain raw materials, good anti-tumor activity, and simple preparation

Inactive Publication Date: 2014-12-10
王深涧
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main treatment for advanced patients is non-surgical treatment. At present, uranium-based combined chemotherapy is still the standard treatment for advanced non-small cell lung cancer, but the overall curative effect is not satisfactory, and the median survival time is mostly between 6.9- 11.3 months, and its toxic and side effects are obvious, seriously affecting the quality of life of patients

Method used

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  • Anti-tumor medicament composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Prescription: Shi Jian Chuan 9g, Schisandra 19g, ginseng 15g, Hedyotis diffusa 15g, Digupi 15g, Pueraria Root 15g, Angelica 15g, Tripterygium 15g, Scutellaria 10g, Codonopsis 18g, Turmeric 14.5g, Curcuma 16g.

[0015] Preparation method: pulverize the full amount of the raw materials of the recipe into fine powder that can pass through a 100-mesh sieve, add 8 times the total weight of the medicinal materials, soak for 30 minutes, decoct 3 times for 2 hours each time, filter, combine the filtrate, and decompress the filtrate The extract concentrated to a relative density of 1.15-1.20, the relative density is the test result at 60 ° C, add ethanol to the alcohol content of 75% (v / v), let stand for 24 hours, take the supernatant, reduce the pressure Concentrate into extract, add pharmaceutically acceptable auxiliary materials, and prepare granules by conventional preparation method.

Embodiment 2

[0017] Prescription: Shi Jian Chuan 9g, Schisandra 19g, ginseng 15g, Hedyotis diffusa 15g, Digupi 15g, Pueraria Root 15g, Angelica 15g, Tripterygium 15g, Scutellaria 10g, Codonopsis 18g, Turmeric 14.5g, Curcuma 16g.

[0018] Preparation method: pulverize the full amount of the raw materials of the recipe into fine powder that can pass through a 100-mesh sieve, add 8 times the total weight of the medicinal materials, soak for 30 minutes, decoct 3 times for 2 hours each time, filter, combine the filtrate, and decompress the filtrate The extract concentrated to a relative density of 1.15-1.20, the relative density is the test result at 60 ° C, add ethanol to the alcohol content of 75% (v / v), let stand for 24 hours, take the supernatant, reduce the pressure Concentrate into extract, add pharmaceutically acceptable excipients, and use conventional preparation methods to prepare tablets.

Embodiment 3

[0020] Prescription: Shi Jian Chuan 9g, Schisandra 19g, ginseng 15g, Hedyotis diffusa 15g, Digupi 15g, Pueraria Root 15g, Angelica 15g, Tripterygium 15g, Scutellaria 10g, Codonopsis 18g, Turmeric 14.5g, Curcuma 16g.

[0021] Preparation method: pulverize the full amount of the raw materials of the recipe into fine powder that can pass through a 100-mesh sieve, add 8 times the total weight of the medicinal materials, soak for 30 minutes, decoct 3 times for 2 hours each time, filter, combine the filtrate, and decompress the filtrate The extract concentrated to a relative density of 1.15-1.20, the relative density is the test result at 60 ° C, add ethanol to the alcohol content of 75% (v / v), let stand for 24 hours, take the supernatant, reduce the pressure Concentrate into extract, add pharmaceutically acceptable excipients, and make capsules by conventional preparation methods.

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Abstract

The invention belongs to the technical field of medicines, specifically relates to an anti-tumor medicament composition, and particularly relates to a traditional Chinese medicinal preparation for treating lung cancer and a preparation method of traditional Chinese medicinal preparation. According to the technical scheme, the medicament composition consists of salvia chinensis, fructus schizandrae, ginseng, oldenlandia diffusa, cortex lycii radicis, puerarin, angelica sinensis, tripterygium glycosides, radix scutellariae, radix codonopsis, carapax trionycis and curcuma zedoary. The medicament composition is scientific, reasonable, simple and effective; all the raw materials are combined to cooperatively work and achieve the effects of clearing away toxin, resisting cancer, softening hard lumps, dispelling nodes and promoting blood circulation to remove blood stasis. The medicament composition can obviously reduce the weight of a tumor and is high in tumor suppression rate.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to an anti-tumor pharmaceutical composition, in particular to a traditional Chinese medicine preparation for treating lung cancer and a preparation method thereof. Background technique [0002] Lung cancer is one of the most common malignant tumors, and its morbidity and mortality are increasing year by year. In some countries and regions, the morbidity and mortality of lung cancer have already ranked first among various malignant tumors. [0003] If the lung cancer is in the early stage, the prognosis is acceptable by surgical treatment, but clinically, about 80% of the lung cancer patients are in the advanced stage, and the treatment is generally based on radiotherapy and chemotherapy. The remission period is short and the toxic and side effects are relatively large, so that the patient's survival period cannot be prolonged, and even has a greater negative impact on the quality o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/56
Inventor 李建美
Owner 王深涧
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