225 results about "Oldenlandia diffusa" patented technology

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating triple negative breast cancer and application thereof. The traditional Chinese medicine composition is prepared from the following main active ingredients in parts by mass: 20 to 40 parts of radix astragali seu hedysari, 10 to 20 parts of rhizoma curcumae, 10 to 20 parts of herba hedyotidis diffusae, 5 to 15 parts of fructus aurantii immaturus, 5 to 15 parts of radix bupleuri, 5 to 15 parts of radix paeoniae alba and 5 to 15 parts of liquorice root. Animal experiments show that the traditional Chinese medicine composition can significantly inhibit tumor growth and pulmonary metastasis of triple-negative breast cancer tumor-bearing mice, increase the proportion of CD8 + T lymphocytes in blood, reduce the proportion of MDSCs, significantly down-regulate the expression of pro-inflammatory cytokines such as IL-6, IL-1alpha, CXCL1 and GM-CSF in serum, and cooperate with PD-L1 immunotherapy to achieve a synergistic effect. And the whole blood and liver and kidney function indexes are in a normal range. Therefore, the traditional Chinese medicine composition disclosed by the invention can be used for effectively inhibiting the tumor growth and pulmonary metastasis of the triple negative breast cancer, remodeling the immune state of an organism and reducing the release of proinflammatory factors, and is safe, reliable, free of obvious liver and kidney toxicity and blood toxicity and small in side effect.

The invention discloses a pharmaceutical composition for treating hashimoto thyroiditis, and belongs to the technical field of traditional Chinese medicines. According to the pharmaceutical composition, astragalus membranaceus and codonopsis pilosula are used as monarch drugs to tonify qi, raise yang, tonify qi and strengthen body resistance; radix bupleuri, rhizoma cyperi and radix curcumae are used as ministerial drugs for soothing liver-qi stagnation, expelling evil, soothing liver-qi, regulating qi and harmonizing blood; humifuse euphorbia herb, lucid ganoderma and oldenlandia diffusa are used as adjuvant drugs for clearing away heat and toxic materials, reinforcing qi, nourishing blood and tranquilizing; the whole formula has the effects of tonifying qi, soothing the liver and clearing heat together. All the medicines are combined to effectively improve the symptoms of patients with hashimoto thyroiditis and reduce the thyroid autoantibody level. In addition, the pharmaceutical composition is good in safety, and a traditional Chinese and western medicine combined treatment strategy for hashimoto thyroiditis can be further popularized in the future.

The invention relates to the technical field of biological medicines, and provides a pharmaceutical composition for treating liver cancer, which is prepared from the following raw material medicines in parts by weight: 3 to 8 parts of radix paeoniae rubra, 1 to 3 parts of fructus sophorae, 3 to 10 parts of rhizoma polygoni cuspidati, 3 to 20 parts of spica prunellae, 3 to 20 parts of herba hedyotidis diffusae, 3 to 10 parts of herba violae, 2 to 5 parts of turtle shell, 1 to 5 parts of radix angelicae sinensis, 1 to 3 parts of rhizoma curcumae, 1 to 3 parts of apios fortunei maxim and 3 to 5 parts of fructus polygoni orientalis. According to the technical scheme, the problems that in the prior art, after radiotherapy and chemotherapy are conducted on patients, obvious side effects can be generated, such as the symptoms of inappetence, nausea and vomiting, diarrhea, stomachache, dental ulcer and the like, and some patients have the symptoms of listlessness, weakness, shortness of breath, alopecia and the like are solved.

The invention relates to a traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material medicines in parts by mass: 50-200 parts of silybum marianum, 50-200 parts of schisandra chinensis, 50-200 parts of gentiana macrophylla, 50-200 parts of andrographis paniculata, 50-200 parts of radix paeoniae alba, 50-200 parts of oldenlandia diffusa, 50-200 parts of folium isatidis and 50-200 parts of patrinia. The traditional Chinese medicine composition has the effects of resisting endotoxin, inflammation, allergy and liver injury and the like, and effectively prevents and treats the liver rupture syndrome of the broiler breeders.

The invention discloses a traditional Chinese medicine composition for treating severe acne as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine monomers in parts by weight: 10-20 parts of folium eriobotryae, 8-15 parts of honeysuckle, 6-12 parts of radix sophorae flavescentis, 5-15 parts of chrysanthemum, 8-15 parts of fructus arctii, 6-12 parts of cortex phellodendri, 10-20 parts of cortex mori radicis, 15-30 parts of oldenlandia diffusa, 15-30 parts of dandelion, 10-20 parts of lalang grass rhizome, 15-30 parts of calcined oyster shell, 6-12 parts of radix angelicae, 8-15 parts of oriental wormwood, 10-20 parts of radix paeoniae rubra, 3-9 parts of coptis chinensis and 10-20 parts of fructus forsythiae. , 10-20 parts of red sage root, 15-30 parts of Chinese violet, 6-12 parts of thunberg fritillary bulb, and 10-20 parts of prunella vulgaris. According to the traditional Chinese medicine formula, the effects of multiple traditional Chinese medicines are integrated, the effects of clearing away heat and drying dampness, cooling blood and detoxifying, and removing stasis and diminishing swelling are synergistically achieved, effective adjustment can be conducted on the constitution of acne patients with damp-heat in the lung and the stomach and heat toxin stasis, and the pathogenesis of acne is fundamentally improved.

The invention discloses a compound traditional Chinese medicine acne gel preparation as well as a preparation method and application thereof, the traditional Chinese medicine raw materials comprise nine traditional Chinese medicines such as salvia miltiorrhiza, scutellaria baicalensis, oldenlandia diffusa, centella asiatica, wild chrysanthemum flower, safflower, honeysuckle, mangnolia officinalis and liquorice, and the gel preparation is prepared. The acne treatment effect is achieved through the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, promoting qi circulation to remove dampness and the like.

The invention discloses blood-activating and stasis-removing massage cream and a preparation method thereof, and belongs to the technical field of daily chemical products. According to the massage cream capable of promoting blood circulation and removing stasis, active substances including caffeine, a ginger root extract, heparin sodium, oldenlandia diffusa, a pseudo-ginseng root extract, a carthamus tinctorius TINCTORIUS extract, a palmata pedunculata PALMATA extract and vanillyl butyl ether are added, and after the massage cream is smeared to a body for massage, the effects of moistening skin, removing stasis and promoting blood microcirculation can be achieved, so that the skin is healthier.

The invention discloses a traditional Chinese medicine compound exosome for treating ovarian cancer and a preparation method and application thereof. The preparation method of the traditional Chinese medicine compound exosome comprises the following steps: (1) soaking the raw material medicines in the traditional Chinese medicine compound in deionized water, boiling with big fire, and decocting for 35-45 minutes; then adjusting to slow fire, and continuously decocting for 30-35 minutes to obtain the traditional Chinese medicine compound water decoction. (2) preparing the traditional Chinese medicine compound exosome from the traditional Chinese medicine compound water decoction by an ultracentrifugation method; wherein the traditional Chinese medicine compound comprises the following raw material medicines: astragalus membranaceus, bighead atractylodes rhizome, cinnamon, curcuma zedoary, fructus lycii, seaweed, pericarpium citri reticulatae viride, lindera aggregata, turtle shell, oldenlandia diffusa, scorpio, artemisia apiacea, arisaema cum bile, edible tulip and radix ranunculi ternati. The prepared traditional Chinese medicine compound exosome can be used for treating ovarian cancer, and the curative effect of the exosome is superior to that of a traditional traditional Chinese medicine compound administration mode.

The invention discloses a production process of a tumor swelling and pain relieving cataplasm patch, and belongs to the technical field of traditional Chinese medicine preparations. According to the process, rheum officinale, golden cypress, turmeric and tripterygium wilfordii stir-fried with vinegar are taken as monarch drugs and are matched with sculellaria barbata and oldenlandia diffusa to enhance the antitumor activity, pseudo-ginseng synergistically improves the transdermal efficiency, and the preparation is optimized through a segmented extraction and nano-targeting technology: 1) adopting supercritical COextraction to extract angelica dahurica and cinnamon volatile oil (20-25MPa and 40-50 DEG C), and carrying out beta-cyclodextrin inclusion; the preparation method comprises the following steps of (1) performing dynamic countercurrent extraction on non-volatile components (70% ethanol at a flow rate of 2.0 mL / min) of other medicinal materials, and coating triptolide (with a particle size of 80-150 nm) in combination with PLGA nanoparticles, and (3) mixing the extract and a composite matrix (sodium polyacrylate-sodium carboxymethyl cellulose-azone), and coating a pH response type chitosan-sodium alginate sustained release layer with the mixture to form the breathable patch.

The invention belongs to the technical field of traditional Chinese medicine detection, and particularly relates to a thin-layer chromatography identification method for the flavor of whole medicines in Houshuning tablets. The thin-layer chromatography identification method for the flavor of the whole medicine in the Houshuning tablet, provided by the invention, comprises the following steps: S1, preparing a test solution of the Houshuning tablet; s2, preparing a reference medicinal material solution of spreading hedyotis herb, common andrographis herb and screwtree root; s3, adopting a polyamide thin-layer plate, taking absolute ethyl alcohol-acetic acid-water as a developing solvent, spraying an aluminum trichloride-ethanol solution for inspection, and performing thin-layer chromatography identification. According to the method disclosed by the invention, the method exclusively used for identifying the flavonoid components of the three medicinal materials in the prescription of the Houshuning tablet is established, the improvement of quality control of the Houshuning tablet is promoted, and meanwhile, the method can be used as a reference for researching the quality of the flavonoid components of the single medicinal materials such as oldenlandia diffusa, andrographis paniculata and helicteres angustifolia; and the blank of oldenlandia diffusa, andrographis paniculata and helicteres angustifolia in the aspect of flavone thin-layer chromatography identification is filled.

The traditional Chinese medicine composition is characterized by being prepared by extracting the following traditional Chinese medicinal materials in parts by weight: 10-20 parts of radix astragali preparata, 10-20 parts of oldenlandia diffusa, 10-14 parts of radix pseudostellariae, 10-14 parts of roasted rhizoma atractylodis macrocephalae, 10-14 parts of poria cocos, 5-10 parts of albizia flower, 6-12 parts of radix ophiopogonis, 3-9 parts of paris polyphylla, 6-12 parts of processed rhizoma arisaematis, 6-12 parts of vinegar-processed curcuma zedoary and 2-4 parts of honey-fried licorice root. The traditional Chinese medicine composition has the effects of strengthening the body resistance and eliminating evil, combining purgation and tonification and treating both symptoms and root causes, has the effects of strengthening the body resistance and strengthening the spleen, resolving depression and relieving restlessness, and eliminating cancer and detoxifying, and is beneficial to improving various clinical symptoms of cancer fatigue patients.

The application belongs to the field of traditional Chinese medicines, and particularly relates to a more low-irritation analgesic ancient prescription microemulsion gel and application thereof in anti-arthritis drugs. The application finds that after water-soluble and fat-soluble components of black plaster prepared from raw frankincense, myrrh, eaglewood, dragon's blood, Strychnos nux-vomica, Panax notoginseng, Oldenlandia diffusa, Venenum Bufonis, bovine bezoar, Stachys jamaicensis, Platycodon grandiflorum, Hirudo nipponia, Tinea, Solenopsis geminata, Scorpio, scorpio, red lead and sesame oil are extracted, a more low-irritation analgesic ancient prescription microemulsion gel is prepared; compared with the black plaster itself, the analgesic effect of the microemulsion gel is significantly improved, and the microemulsion gel has good anti-inflammatory effect and can be used for preparing anti-arthritis drugs; and the microemulsion gel has reduced toxicity and is more convenient to use.

The invention provides a broad-spectrum combined medicine for treating colorectal cancer. The broad-spectrum combined medicine is prepared from the following components in parts by weight: 100 parts of purified water, 38 to 90 parts of tripterygium wilfordii alkaloid, 38 to 90 parts of tripterygium hypoglaucum alkaloid, 28 to 85 parts of chamaejasmine, 28 to 85 parts of gelsmium elegans alkaloid and 28 to 85 parts of xanthoxylin. The medicine is prepared from the following raw materials in parts by weight: 16 to 80 parts of ganoderan, 16 to 80 parts of pinellia ternate sitosterol, 16 to 80 parts of radix rehmanniae praeparata, 16 to 80 parts of astragaloside, 16 to 80 parts of oldenlandia diffusa alkaloid, 16 to 80 parts of sculellaria barbata alkaloid, 16 to 80 parts of tanshinone, 16 to 80 parts of carthamin, 16 to 80 parts of honeysuckle chlorogenic acid and 16 to 80 parts of pericarpium citri reticulatae flavone. By integrating anti-tumor components with multiple action mechanisms, tripterygium wilfordii alkaloid, tripterygium hypoglaucum alkaloid and the like, tumor cell proliferation can be directly inhibited, and apoptosis can be induced; tanshinone, emodin and the like can inhibit tumor angiogenesis; ganoderma lucidum polysaccharides, astragaloside and the like can activate the immune system of the body, enhance the activity of T cells and NK cells, and form double strikes of direct killing and immune surveillance.

The composition is composed of a herbal medicine alcohol extract and an alcohol solvent, the herbal medicine comprises Jinfo grass, radix angelicae, solidago decurrens, oldenlandia diffusa, fructus kochiae, fructus cnidii, bletilla striata, radix clematidis, cortex dictamni, portulaca grandiflora and gallnut, and the herbal medicine is scientifically proportioned according to the principle of monarch, minister and guide. The preparation method comprises the following steps: processing medicinal materials such as fructus cnidii, crushing, soaking with high-concentration alcohol according to a specific ratio, extracting, and finally filling into a spray bottle. The traditional Chinese medicine composition integrates multiple functions of disinfection, hemostasis, detumescence, pain relieving, itching relieving and the like, is suitable for multiple skin problems such as traumatic bleeding, burns and scalds, eczema and mosquito bites, and can be used for skin disinfection during epidemic situations so as to reduce epidemic risks. The product takes effect quickly, is convenient to use and is safe and effective, and the preparation process integrates tradition and efficiency.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.

The present application relates to a kind of anti-non-small cell lung cancer for strengthening healthy qi and resolving stasis and preparation method thereof, strengthening healthy qi and resolving stasis is made from the following weight proportion of raw medicinal materials: Ficus pumila 2g~50g / portion, radix pseudostellariae 2g~50g / portion, poria cocos 2g~50g / portion, atractylodes 2g~50g / portion, radix scutellariae 2g~50g / portion, oldenlandia 2g~50g / portion, cat's paw grass 2g~50g / portion, giant knotweed 2g~50g / portion, curcuma zedoary 2g~50g / portion, oyster 2g~50g / portion, platycodon 2g~50g / portion, mountain bitterling 2g~50g / portion, half branch orchid 2g~50g / portion. By cell test and the construction NSCLC osimertin drug resistance animal model prove, strengthening healthy qi and resolving stasis of the present application can adjust tumor microenvironment (TME) and inhibit non-small cell lung cancer cell growth of osimertin drug resistance. Not only this, strengthening healthy qi and resolving stasis of the present application can also inhibit common non-small cell lung cancer cell growth. While clinical observation finds, strengthening healthy qi and resolving stasis of the present application can improve insomnia, skin rash, diarrhea and other symptoms of lung accumulation (lung cancer, lung nodule) patient, improve its quality of life.

The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of radix codonopsis, 10 to 20 parts of rhizoma atractylodis macrocephalae, 10 to 15 parts of poria cocos, 10 to 12 parts of pericarpium citri reticulatae, 6 to 10 parts of rhizoma pinellinae praeparata, 10 to 12 parts of radix aucklandiae, 10 to 12 parts of rhizoma corydalis, 3 to 6 parts of radix notoginseng, 10 to 12 parts of fructus aurantii immaturus, 10 to 20 parts of radix ginseng rubra, 15 to 30 parts of herba hedyotidis diffusae, 15 to 30 parts of semen coicis, 10 to 15 parts of rhizoma curcumae, 10 to 20 parts of radix salviae miltiorrhizae, 10 to 20 parts of radix astragali seu hedysari and 3 to 6 parts of liquorice root. The invention further discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition aims at chronic atrophic gastritis with pathological characteristics of gastric mucosa dysplasia and intestinal metaplasia, and is remarkable in curative effect and small in side effect through reasonable medicine compatibility.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

This invention provides a traditional Chinese medicine composition for treating ectopic pregnancy, its enema preparation, and its application. A traditional Chinese medicine enema composition for ectopic pregnancy comprises the following raw materials in parts by weight: 28-35 parts of *Ilex pubescens*, 18-23 parts of rhubarb, 18-23 parts of *Hedyotis diffusa*, 18-23 parts of *Liquidambar formosana*, and 18-23 parts of safflower. This invention also provides a traditional Chinese medicine enema preparation for ectopic pregnancy, comprising the traditional Chinese medicine composition described in any one of the present invention, preferably an enema preparation. This invention targets ectopic pregnancy, using *Ilex pubescens* as the principal herb, and safflower and *Liquidambar formosana* as assistant herbs to enhance the blood-activating and stasis-removing effects of *Ilex pubescens*; rhubarb as the adjuvant herb; and *Hedyotis diffusa* as the guiding herb. The precise combination of these herbs effectively activates blood circulation, clears the meridians, removes stasis, and eliminates masses, resulting in a good therapeutic effect for ectopic pregnancy. This invention uses *Ilex pubescens*, rhubarb, *Hedyotis diffusa*, *Liquidambar formosana*, and safflower in a certain proportion, which has a synergistic effect, resulting in a high cure rate for ectopic pregnancy and good safety.

The invention discloses application of body resistance strengthening Ermiao detoxification granules in preparation of anti-human papilloma virus drugs, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine is characterized by being prepared from the following components in parts by weight: 30 parts of astragalus membranaceus, 15 parts of codonopsis pilosula, 12 parts of bighead atractylodes rhizome, 15 parts of poria cocos, 9 parts of rhizoma atractylodis, 6 parts of golden cypress, 10 parts of paris polyphylla, 10 parts of rhizoma smilacis glabrae, 10 parts of sculellaria barbata, 10 parts of Chinese lobelia, 15 parts of patrinia, 30 parts of coix seeds, 15 parts of oldenlandia diffusa and 6 parts of liquorice. The number of infected HPV subtypes before treatment, the total score of traditional Chinese medicine syndromes, the TCT result and the pathological result have no significant statistical difference (P is greater than 0.05); after treatment, traditional Chinese medicine syndrome points and clinical index curative effects have a significant statistical difference (Plt; and 0.05), so that the healthy-energy-strengthening ermiao toxin-clearing granules have a remarkable curative effect on high-risk HPV infected patients.

The invention relates to the technical field of medicines for treating intestinal ischemia-reperfusion injury, and discloses a medicine for treating intestinal ischemia-reperfusion injury and a preparation method thereof. Comprising 10 to 25 parts of rosmarinic acid, 5 to 15 parts of betaine, 3 to 10 parts of glutamine, 10 to 25 parts of salvianolic acid B, 5 to 15 parts of astragaloside, 3 to 10 parts of ginsenoside Rg1, 2 to 8 parts of curcumin, 5 to 12 parts of ophiopogon japonicus polysaccharide, 2 to 6 parts of notoginsenoside R1, 3 to 7 parts of total flavonoids of oldenlandia diffusa and 4 to 9 parts of angelica sinensis polysaccharide. The medicine disclosed by the invention can be used for relieving intestinal edema, repairing oxidative injury, clearing excessive ROS, improving SOD activity, blocking oxidative stress injury, inhibiting epithelial cell apoptosis, reducing intestinal permeability and maintaining mucous membrane integrity, and has an excellent treatment effect on intestinal ischemia reperfusion injury.

The invention relates to a body resistance strengthening and stagnation eliminating prescription for resisting non-small cell lung cancer and a preparation method thereof. The body resistance strengthening and stagnation eliminating prescription is prepared from the following raw material medicines in parts by weight: 2-50g / part of radix fici simplicissimae, 2-50g / part of radix pseudostellariae, 2-50g / part of poria cocos, 2-50g / part of rhizoma atractylodis macrocephalae, 2-50g / part of radix scutellariae, 2-50g / part of oldenlandia diffusa, 2-50g / part of radix ranunculi ternati, 2-50g / part of polygonum cuspidatum, 2-50g / part of curcuma zedoary, 2-50g / part of oyster, 2-50g / part of platycodon grandiflorum, 2-50g / part of edible tulip and 2-50g / part of sculellaria barbata. Cell tests and construction of an NSCLC osimertinib-resistant animal model prove that the body resistance strengthening and stagnation eliminating prescription can regulate a tumor microenvironment (TME) and inhibit growth of osimertinib-resistant non-small cell lung cancer cells. In addition, the formula for strengthening the body resistance and removing stasis can also inhibit growth of common non-small cell lung cancer cells. Meanwhile, clinical observation finds that the body resistance strengthening and stasis removing prescription can improve symptoms such as insomnia, rash and diarrhea of patients with lung accumulation (lung cancer and pulmonary nodule), and improve the life quality of the patients.

The invention patent is titled "Dragon and Cypress Gel," belonging to the pharmaceutical category. The main components of Dragon and Cypress Gel are: Phellodendron bark, earthworm, dragon's blood, Oldenlandia diffusa, Sophora flavescens, and Bletilla striata. In recent years, research on cervicitis and cervical lesions has shown good results using external treatments of traditional Chinese medicine. Vaginal cervical medications are characterized by high local drug concentration, low dosage, and safety and effectiveness, receiving high clinical evaluation. The vagina and cervix have abundant capillaries and lymphatic vessels, and lack clearly defined nerve endings, resulting in minimal pain stimulation for patients during administration. This makes it an effective drug release site for specific diseases such as cervicitis and vaginitis. Traditional Chinese medicine gels are a novel type of external preparation of traditional Chinese medicine. They are made by dissolving or uniformly dispersing traditional Chinese medicine in a gel. These gels adhere tightly to the treatment site for a relatively long time, exhibiting good bioadhesion, and are simple to prepare. It is suitable for use on skin, mucous membranes and cavities. It not only avoids the first-pass effect of enzymes and acids in the gastrointestinal tract that exists in oral administration, but also reduces the adverse reactions of drugs. It has the characteristics of good spreadability, non-greasy feeling, easy to wash off, good transdermal absorption, and comfortable use.

The invention discloses a traditional Chinese medicine compound for reducing the occurrence risk of liver cancer by improving a liver regeneration microenvironment and a preparation method of the traditional Chinese medicine compound. The traditional Chinese medicine compound is prepared by the following steps: adding water into five traditional Chinese medicine decoction pieces such as mistletoe, semen cuscutae, turmeric, oldenlandia diffusa and semen coicis, decocting twice (2 hours each time), combining decoctions, filtering, standing filtrate overnight, taking supernate, concentrating into thick extract, and storing the extract for later use; taking the thick paste, adding a proper amount of starch, uniformly stirring, putting into a drying box, and drying at the temperature of below 80 DEG C; taking out the dried product, weighing, crushing, adding starch until the total weight is 450g, and uniformly mixing for later use; taking the medicinal powder, preparing a soft material by using 80% ethanol, granulating, drying at the temperature of 80 DEG C or below, and finishing granules. And taking the granules, adding 0.3% of magnesium stearate, uniformly mixing, filling into No.0 capsules, preparing 1000 granules (0.45 g per granule), carrying out aluminum-plastic plate pressing, and packaging. The compound traditional Chinese medicine is mainly used for reducing the occurrence risk of liver cancer by improving the liver regeneration microenvironment for chronic liver disease patients.

The invention provides a traditional Chinese medicine composition for treating pulmonary nodules and a preparation method thereof. The traditional Chinese medicine composition is prepared by extracting the following traditional Chinese medicine decoction pieces in parts by weight: 25-35 parts of raw coix seeds, 8-12 parts of platycodon grandiflorum, 8-12 parts of curcuma zedoary, 8-12 parts of radix curcumae, 8-12 parts of salvia chinensis, 8-12 parts of astragalus membranaceus, 8-12 parts of radix pseudostellariae, 8-12 parts of akebia fruits, 10-20 parts of oldenlandia diffusa, 10-20 parts of rabdosia rubescens, 3-7 parts of radix ranunculi ternati and 8-12 parts of glossy privet fruits. The traditional Chinese medicine can be used for treating the phlegm stasis and toxin stagnation syndrome type pulmonary nodule, and fully embodies the treatment principle of clearing damp and reducing phlegm, promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, tonifying qi and lifting yang, replenishing qi and strengthening spleen, promoting salivation and moistening lung, promoting qi circulation to diuresis, promoting qi circulation to relieve pain, strengthening spleen to promote digestion, clearing away heat and toxic materials, promoting diuresis and eliminating carbuncle, promoting blood circulation to relieve pain, nourishing liver and kidney, and preventing blood-activating drugs from consuming blood and injuring yin; the traditional Chinese medicine is an effective prescription for treating the phlegm stasis and toxin stagnation syndrome type pulmonary nodule.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating psoriasis as well as a preparation method and application thereof. The traditional Chinese medicine composition for treating psoriasis is characterized by being prepared from the following raw materials in parts by weight: 2 to 16 parts of radix gentianae macrophyllae, 4 to 11 parts of radix sophorae flavescentis, 14 to 31 parts of herba hedyotidis diffusae, 14 to 31 parts of caulis lonicerae, 9 to 16 parts of caulis spatholobi and 9 to 16 parts of ramulus uncariae cum uncis. The traditional Chinese medicine composition for treating psoriasis not only plays a local treatment role through mechanisms of penetrating through striae and interstices, relaxing meridians, regulating qi and blood, expelling evil and strengthening body resistance and the like, but also penetrates into viscera through skin hair orifices to play a role of internal and external combined treatment. The traditional Chinese medicine composition is simple and convenient to use, convenient to carry and easy to popularize, the medication compliance of patients is effectively improved, and a guarantee is provided for the continuity of psoriasis treatment.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an external traditional Chinese medicine composition for promoting wound healing after perineotomy as well as a preparation method and application of the external traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 15 to 60 parts of spreading hedyotis herb, 10 to 15 parts of honeysuckle flower, 6 to 15 parts of fructus forsythiae, 10 to 30 parts of herba taraxaci, 5 to 15 parts of radix angelicae sinensis, 10 to 15 parts of radix rubiae, 10 to 30 parts of herba leonuri, 0.3 to 1 part of pearl powder, 3 to 10 parts of rhizoma bletillae, 10 to 15 parts of carbonized sanguisorba root, 10 to 60 parts of radix astragali seu hedysari, 2 to 10 parts of catechu, 10 to 30 parts of calcined dragon bone, 5 to 15 parts of rhizoma atractylodis macrocephalae, 2 to 10 parts of liquorice root and 10 to 20 parts of red halloysite. By the adoption of the components, wound detumescence, inflammation diminishing, tissue regeneration promoting and healing accelerating processes can be remarkably promoted, two preparation processes of liquid medicine and freeze-dried powder are provided, and the liquid medicine preparation can be used immediately after being unsealed and is convenient to use; the freeze-dried powder preparation retains heat-sensitive components and is long in shelf life.

The invention discloses a traditional Chinese medicine external nursing medicine for treating burns and scalds. The traditional Chinese medicine external nursing medicine comprises the following raw material medicines and auxiliary materials in parts by weight, raw material medicines: 8-12 parts of dandelion, 6-8 parts of oldenlandia diffusa, 8-10 parts of purpleflower holly leaf, 8-10 parts of Chinese elm bark, 10-12 parts of calcined dragon bone, 6-8 parts of aloe, 8-10 parts of safflower, 8-10 parts of radix angelicae, 8-10 parts of astragalus membranaceus, 3-5 parts of borneol, 2-4 parts of pearl powder, 1-3 parts of a salvia miltiorrhiza extract, 8-10 parts of golden cypress, 6-8 parts of sanguisorba officinalis and 4-6 parts of rheum officinale; auxiliary materials: 5-10 parts of chitosan, 3-6 parts of hyaluronic acid, 10-20 parts of olive oil and 1-2 parts of nano titanium dioxide; the pearl powder, the radix salviae miltiorrhizae extract, the cortex phellodendri, the radix sanguisorbae and the radix et rhizoma rhei are added to construct an anti-infection-healing promoting-scar inhibiting triple-effect synergistic system, and pharmacodynamic experiments prove that the deep II-degree wound healing time can be shortened by 3-5 days, and the scar hyperplasia degree can be reduced by 40%; the temperature-sensitive hydrogel realizes'gelation when being contacted with skin ', is uniformly coated and is not easy to fall off.

The invention discloses a compound traditional Chinese medicine preparation for improving tumor immunity and resisting tumors, belongs to the technical field of anti-tumor traditional Chinese medicines, and discloses a compound traditional Chinese medicine preparation for improving tumor immunity and resisting tumors. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-25 parts of ginseng, 15-18 parts of selfheal, 12-18 parts of seaweed, 12-19 parts of astragalus membranaceus, 10-16 parts of angelica sinensis, 18-30 parts of oldenlandia diffusa, 10-15 parts of fleece-flower root, 10-14 parts of poria cocos, 10-16 parts of thunberg fritillary bulb, 8-14 parts of pseudobulbus cremastrae seu pleiones and 8-17 parts of curcuma zedoary. Through the specific pharmacological action, growth and proliferation of thyroid tumor cells are inhibited, the development speed of tumors can be slowed down, the malignancy degree of the tumors can be reduced, apoptosis of the thyroid tumor cells can be induced, and the number of the tumor cells can be effectively reduced by inducing apoptosis of the tumor cells, so that the anti-tumor purpose is achieved.

The invention discloses a traditional Chinese medicine composition for treating constipation as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition comprises the following components in parts by weight: 45 to 85 parts of Chinese pulsatilla root, 45 to 85 parts of oldenlandia diffusa, 45 to 85 parts of sculellaria barbata, 80 to 140 parts of Chinese actinidia root, 45 to 85 parts of trogopterus dung, 80 to 140 parts of coix seed, 80 to 140 parts of poria cocos, 80 to 140 parts of rhizoma pinellinae praeparata, 45 to 85 parts of pericarpium citri reticulatae, 60 to 100 parts of bighead atractylodes rhizome, 45 to 85 parts of endothelium corneum gigeriae galli, 60 to 100 parts of white hyacinth bean, 60 to 100 parts of dried ginger and 45 to 85 parts of liquorice. The traditional Chinese medicine composition has a good treatment effect on constipation caused by gastrointestinal tumors, is mild in medicine property, and is specially developed for patients with constipation caused by tumors.