82results about How to "Fast drug effect" patented technology

The invention provides a pesticide suspension concentrate containing pleocidin and a preparation method thereof. The suspension concentrate comprises active ingredients such as pleocidin and abamectin, emamectin benzoate, lambda-cyhalothrin, beta-cypermethrin, chlorfenapyr, chlorfluazuron, diafenthiuron, lufenuron, thiamethoxam or butene-fipronil, as well as dispersing agent, wetting agent, functional aids, other aids and water. The preparation method is as follows: mixing the active ingredients, aids and water to a homogeneous pasty material, and then feeding into a sand mill to obtain a mean grain size of 2-4mu m (4.3) by the sand milling. The suspension concentrate of the invention has a small mean grain size, high suspension rate of the product, stable performance and minimal condensate rate under storage at room temperature within two years. Furthermore, as the suspension rate of the preparation is high and the added functional aids increase spreadability and permeability, the pharmacodynamic action of the product is improved.

The invention discloses a herbicide-fertilizer for a direct-seeding rice field. The herbicide-fertilizer contains herbicide-fertilizer mixture which is prepared by using bensulfuron-methyl with weeding activity, pretilachlor herbicide and a nitrogen-containing fertilizer, wherein the weight ratio of the bensulfuron-methyl to the pretilachlor is 1:9 and the nitrogen-containing fertilizer consists of urea and ammonium sulfate with weight ratio being 1:2. The invention additionally discloses a production method of the herbicide-fertilizer. Water is used as solvent. A spray-coating method is used for preparing herbicide-fertilizer particle mixture. The process flow is short, the quality is stable and the yield is high. The prepared herbicide-fertilizer is suitable for direct-seeding rice fields, can realize synchronous fertilization and weeding, has the characteristics of high safety, excellent stability and good efficacy, and can achieve the goal of labor saving and time saving.

The invention discloses an aspirin arginine and a preparation method of powder for injection thereof, the preparation method is characterized in that: arginine is dissolved in water, aspirin is further added, the arginine fully reacts with the aspirin in the water by stirring at the reaction temperature of 60-80 DEG C, chloroform is added after the reaction, the low temperature preservation, the precipitation and the filtration are carried out, sediment is washed and vacuum dried, an aspirin arginine crude product is obtained, and then the aseptic packaging or the freeze-drying after the redissolution is carried out to obtain the aspirin arginine powder for injection. The method has short reaction time and high production efficiency, and the obtained aspirin arginine powder for injection has stable product quality.

The present invention relates to one kind of medicine, dextro lipoic amidate and its preparation process. The general expression of dextro lipoic amidate is shown. The present invention changes dextro lipoic with easy oxidation and polymerization, poor heat stability and water insolubility into stable dextro lipoic amidate with raised smelting point and raised medicinal effect. The dextro lipoic amidate may be further used to prepare other medicine preparation.

The invention relates to a medicine for gynecoiatry and health care and a preparation method thereof. The medicine is made of the formulation based on the weight percentage: 2-12% of rhizoma atractylodis, 3-15% of bletilla striata, 2-10% of angelica dahurica, 3-12% of platycodon root, 2-10% of phyllanthus urinaria, 2-10% of saffron, 4-13% of tuckahoe, 4-10% of asiatic plantain seed, 2-10% of radix paeoniae alba, 2-10% of baikal skullcap root, 2-10% of rhizoma coptidis, 3-10% of gentianella, 3-12% of achyranthes, 3-10% of barbed skullcap herb, 3-8% of hibiscus, 2-10% of dictamnus dasycarpus, 2-15% of motherwort, 3-8% of forsythia, 1-10% of angelica, 2-8% of common cnidium fruit, 3-7% of cistanche salsa, 2-8% of salvia chinensis, 1-6% of salvia miltiorrhiza, 1-4% of nut grass and 2-8% of radix curcumae; the total content of the twenty-five drugs is 100%. The medicine has special effects on expulsion of toxin, antiphlogosis and sterilization of gynae, has the functions of stanching, astringing and healing wound, and has the remarkable advantages of no side effect and rapid treatment.

The invention discloses niraparib granules with a high utilization efficiency and a preparation method thereof, and belongs to the technical field of medicine production. The components of the niraparib granules include niraparib, glucose, vitamin C and a carboxylesterase inhibitor. A granule packaging machine adopted in the preparation method comprises a storage bin and a transparent upper discharge pipe, wherein the transparent upper discharge pipe penetrates through the storage bin, the two sides of the upper discharge pipe are provided with an infrared emitter and an infrared receiver respectively, the infrared emitter and the infrared receiver are capable of lifting and lowering, a turntable is arranged below the upper discharge pipe, a curved through hole is formed in the turntable,a retractable stop block with a proximity switch is arranged on one side of the turntable, and a curved groove is formed in the turntable. By adopting the niraparib granules, the amount of niraparib discharged along with excretion can be reduced, and the pharmacodynamic effect of the niraparib can be maintained; valve-related components of the granule packaging machine adopted in the preparation process of the niraparib granules have longer service life, it can be ensured that the amount of the material discharged each time is sufficient, the remaining granules with a remaining amount less than a set value are remained in the upper discharge pipe, and the application is convenient.

The invention relates to a ciclopirox olamine pessary capable of reducing toxic and side effects of a medicament caused by systemic delivery, increasing local concentration of the medicament, fully playing the therapeutic effectiveness of the medicament and improving the adaptability of patients. The pessary can realize zero order release and is prepared by the following materials by weight portion: 1 portion of ciclopirox olamine, 65 to 90 portions of substrate, 0.2 to 3 portions of stearic acid, 0.1 to 5 portions of hydrogenated castor oil and 0.05 to 2 portions of sodium benzoate.

The invention discloses a traditional Chinese medicine composition with efficacy of strengthening and consolidating body resistance, tonifying liver and kidney and enhancing immunity. The traditionalChinese medicine composition is prepared from the following raw material medicines in parts by weight: 3-300 parts of herba epimedii, 3-300 parts of fructus ligustri lucidi, 3-300 parts of radix astragali, 3-300 parts of radix codonopsis, 3-300 parts of radix angelicae sinensis, 3-300 parts of prepared polygoni multiflori radix, 3-300 parts of radix salviae miltiorrhizae, 3-300 parts of glycyrrhizae radix, 3-300 parts of poria and 3-300 parts of fructus lycii. The traditional Chinese medicine composition disclosed by the invention can supplement deficiency of qi and blood of the human body, improve organism immunity, eliminate weak symptoms and treat symptoms, including asthenia of essence and blood, soreness and weakness of waist and knees, insomnia, forgetfulness, dizziness, tinnitus andthe like due to the surgery, the radiotherapy and the chemotherapy of a tumor patient. The traditional Chinese medicine composition can prevent COVID-19 infection.

The invention relates to an organic vegetable pest control medicine. The organic vegetable pest control medicine is prepared from the following raw materials in parts by weight: 120-160 parts of plant ash, 105-135 parts of white radish, 105-135 parts of onions, 90-120 parts of garlic, 90-120 parts of fresh ginger, 85-105 parts of pepper, 85-105 parts of Sichuan pepper, 70-90 parts of pumpkin seeds, 70-90 parts of calamine, 55-75 parts of wormwood, 55-75 parts of mulberry leaves, 50-70 parts of golden cypress, 50-70 parts of gynostemma pentaphyllum, 50-70 parts of piper sarmentosum, 35-50 parts of Chinese honeylocust fruit, 35-55 parts of aqueous sodium chloride solution, 30-50 parts of aqueous magnesium chloride solution, 30-50 parts of aqueous sodium carboxymethylcellulose solution and 5-15 parts of potassium fulvate powder. The invention also discloses a preparation method of the organic vegetable pest control medicine. The organic vegetable pest control medicine has obvious killing effect on ova and larvae; and pharmacodynamical effect is quick, lasting period is long, and multiple pests on fruit trees and vegetables can be effectively controlled.

The invention discloses a chlorfluazuron-containing pesticide suspending agent and a preparation method thereof. The chlorfluazuron-containing pesticide suspending agent comprises: by weight, 0.1 to 40% of an active component A, 0.1 to 40% of an active component B, 2 to 10% of one or more dispersants, 1 to 5% of one or more wetting agents, 1 to 8% of one or more functional auxiliary agents, 0.1 to 4% of one or more thickening agents, 1 to 5% of one or more antifreezing agents, 0 to 1% of one or more antiseptics, 0 to 0.8% of one or more antifoaming agents, 0 to 4% of one or more PH conditioning agents, 0 to 2% of one or more anti-oxidants and 10 to 80% of water. The active component A is chlorfluazuron. The active component B is indoxacarb, tebufenozide, acetamiprid, high-efficiency cyhalothrin, thiamethoxam or butene-fipronil. Compared with the traditional pesticide powder, the chlorfluazuron-containing pesticide suspending agent has better drug effects which are the same as drug effects of missible oil, avoids a large amount of a harmful solvent used in missible oil, and has a small average particle size, a high suspension rate, stable performances and a low water separation amount at a normal temperature in two years.

The invention discloses medical ray protection spray. The protection spray is prepared from active ingredients including SOD (superoxide dismutase), curcumin, sodium alginate, potassium sorbate and sorbitol, and purified water. For the ingredients adopted by the medical ray protection spray, curcumin has the efficacies of resisting bacteria, resisting inflammation and easing pain, potassium sorbate can inhibit the microbial growth, sorbitol has the moisturizing function, meanwhile, sodium alginate is large in molecular weight, the interior of the space structure of sodium alginate contains many loose micropore structures which can wrap SOD in the gel form, and moreover, sodium alginate has the capacity of forming gel, thus improving the stability of SOD (superoxide dismutase). After the protection spray is sprayed to the skin surface of a patient, sodium alginate can control SOD, so that SOD is slowly released, and therefore, the drug action of the product is prolonged and improved.

The invention discloses a quality control method of four-time treated rhizoma cyperi decoction pieces. The quality control method comprises the steps: establishing a four-time treated rhizoma cyperi HPLC fingerprint spectrum, and with an active ingredient alpha-cyperone as a benchmark peak, calculating the content of alpha-cyperone in the benchmark peak; and allowing fingerprint peaks of other main active ingredients to take alpha-cyperone as a reference, calculating the relative contents of the fingerprint peaks of the active ingredients according to alpha-cyperone. The method has operability, can control the relative contents of other unknown main effective ingredients only with the known reference substance alpha-cyperone ingredient content, and is a scientific method achieving control of the quality of the four-time treated rhizoma cyperi decoction pieces. The method is simple, is easy to popularize, reduces the use amount of the reference substance, solves the problems that a market monomeric material reference substance is insufficient and expensive, makes the quality of the four-time treated rhizoma cyperi decoction pieces stable, enhances the pharmacological function, and is conducive to promote rapid development of traditional Chinese medicine industries.

The invention relates to a metformin hydrochloride gastric floating tablet. The metformin hydrochloride gastric floating tablet contains metformin hydrochloride, a polymer gel material, a wax material and a foaming material, wherein the polymer gel material is a mixture of water-soluble resin and lactose; the wax material is at least one of octodecyl alcohol and stearic acid; and the foaming material is a mixture of sodium bicarbonate and magnesium stearate. A preparation method comprises wet process pelletization and powder direct tabletting, wherein the wet process pelletization comprises the following steps: A1) preparing the materials; A2) mixing the materials; A3) pelletizing; and A4) tabletting; and the powder direct tabletting comprises the following steps: B1) preparing the materials; B2) mixing the materials; and B3) tabletting. Each metformin hydrochloride gastric floating tablet contains 0.25-0.75g of metformin hydrochloride. The metformin hydrochloride gastric floating tablet disclosed by the invention has the advantages that after the tablets are taken by a patient, hydrophilic gel is hydrated and expanded, a medicament is simultaneously controlled to be released slowly, the onset of action of the medicament is fast, the medicament effect is lasting and the bioavailability of the medicament is high; and the frequency of taking the tablets of the patient can be reduced, the side effects are reduced, and the incidence rate of poor reactions is also reduced.

The invention discloses a pharmaceutical composition containing a non-narcotic analgesic or a narcotic analgesic and pharmaceutically acceptable salts thereof and fospropofol disodium. The non-narcotic analgesic is nefopam hydrochloride or nefopam. The narcotic analgesic is selected from fentanyl, remifentanil, alfentanil and sufentanil. The pharmaceutical composition can be directly used for clinic comprising anesthesia induction, maintenance of anesthesia, post operation or ICU analgesia, and the like. The pharmaceutical composition has functions of analgesia and sedation. Through addition or synergistic effects of medicines, the pharmaceutical effects are enhanced, the dosage is reduced, untoward effects in pain treatment is prevented and relieved, the number of times of administration by an anesthetist is reduced, and therefore an anesthesia induction process is more convenient and an ideal anesthesia effect can be achieved.

The zedoary extractive is prepared with zedoary oil as material and through chromatography with silica gel column, and contains curdione 30-60 wt%, elemenone 15-40 wt%, neo-curdione 1-15 wt%, curcumenol1-20 wt% and no instable benzofuran derivative. The zedoary extractive has high effect, less side effect and high stability, and may be mixed with different medicine carrier to prepare various medicine preparations, such as capsule and injection, for treating viral diseases, cardiac and cerebral vascular diseases and tumor.

The invention discloses a method for preparing a tripterygium wilfordii extract by using triterpenes as main components and a pharmaceutical application of the triterpenes as main components. The method for preparing the tripterygium wilfordii extract by using triterpenes as main components comprises the following steps: (1) crushing a dried tripterygium wilfordii root medicinal material, screening through a screen of 10-40 meshes, and weighing 150-200g of powder; (2) performing ultrasonic extraction with an extracting solvent, wherein the usage ratio of the extracting solvent to the medicinal materials is (8-16)ml:1g; filtering the extract, reclaiming the filtrate at reduced pressure to extract the solvent to obtain concentrate, and drying to obtain a coarse product of tripterygium wilfordii extract; and (3) adding 5.0-15.0g of the coarse product of tripterygium wilfordii extract into a solvent for re-dissolving, wherein the usage ratio of the solvent to the coarse product of tripterygium wilfordii extract is (10-15)ml:1g, filtering, and reclaiming the solvent at reduced pressure to obtain the tripterygium wilfordii extract. The invention also discloses a medicament prepared from the tripterygium wilfordii extract for treating rheumatoid arthritis. The content of total triterpenes of the prepared tripterygium wilfordii extract is 50-75 percent, so that the utilization of a tripterygium wilfordii medicinal material is improved, and the toxicity of the tripterygium wilfordii medicinal material is reduced.

An injection of compound xylazine for the anesthesia of wild animal is prepared through dissolving xylazine and EDTA in distilled water, adding the solution of dihydroetorphine hydrochloride, stirring, filling it in ampules, and sterilizing.

The invention relates to an angelica polymorpha maxim extract, which contains coumarin and phenylchromone components, wherein the coumarins include one or more of oxypeucedanin hydrate, pabulenol, isoimperatorin, osthol, bergapten, imperatorin, 22,23-dihydroavermectin, isopimpinellin and oxypeucedanin ethylether; and the phenylchromones include one or more of 3'R-(+)hamaudol, 3',-O-acetylhamaudol, angeliticin and ledebouriellol. The invention also relates to a preparation method, a quality control method and a medicinal composition of angelica polymorpha maxim extract and use of the angelica polymorpha maxim extract in the preparation of medicines or products for treating pain and/or inflammatory disorders. The experiments on the pharmacodynamic and acute toxicity of the extract indicate that the extract has the advantages that: the active ingredients are clear; the medicinal effect is remarkable; the toxic and side effects are small; the product quality is high; the dosage is small; the quality is controllable; and the like.

The invention aims to provide a sinomenine preparation. The preparation is prepared from sinomenine with a proper concentration, ostrich oil, vitamin E with a proper concentration and eucalyptus oil. The preparation method comprises the following steps: heating and melting the ostrich oil into liquid; adding sinomenine powder, and uniformly stirring and dispersing; adding eucalyptus oil and vitamin E, stirring and cooling. According to the preparation, the transdermal effect of sinomenine can be improved and the drug effect of the medicine can be improved; ostrich oil is a pure natural raw material, is capable of reducing skin irritation when used as a drug-loading matrix; in addition, ostrich oil has arthritis resistance and can realize arthritis treatment when used together with sinomenine.

The invention relates to the technical field of agricultural production, in particular to a method for rapid growth of fish. The method comprises the steps of (1) pond treatment, wherein a pond is under the blazing sun for 7 days before fry are put in the pond, then quicklime is added to sludge on the bottom of the pond for pond disinfection, before water introduction, a mixture of fermented fowlmanure and straw is added into the pond, and the mixture of fermented fowl manure and straw is mixed with the topsoil on the bottom of the pond; (2) fry treatment, wherein healthy and undamaged fry are selected, immersed in 100-200 ppm of Formalin solution and subjected to dipping bath for 1 hour; (3) fry feeding, wherein the fry are fed with fattening Chinese herbal medicine feed every day afterput in the pond, and feeding is conducted at three times every day. By means of the method, fish can rapidly grow and get fattened.