194results about How to "Active ingredients are clear" patented technology

An extract of mulberry twigs is dislcosed, which can be used to prepare the food or the medicine to cure hyperuricemia and gout diseases. The said extract is prepared from mulberry twigs through extracting in solvent (aqueous solution of alcohol, chloroform, acetone, etc) at 10-100 deg.C more than one time, mergint the liquid extracts, recovering solvent, regulating pH value to 7.5-9.5, centrifugal separation to obtain supernatant, regulating pH value to 4-6, deposition, water washing wand drying. Several other approaches for purifying it are also disclosed.

The invention relates to a preparation method of effective fractions of shining wintersweet leaf, a preparation method and a use of a preparation thereof, in particular to an application of the effective fractions of the shining wintersweet leaf and the preparation thereof in drugs used for preventing and treating respiratory system diseases as well as in anti-cold drugs, antimicrobial drugs, anti-inflammation drugs, antiviral drugs, antifungal drugs, etc. In the invention, the volatile effective fractions and non-volatile effective fractions are added to the crude drug of the shining wintersweet medicinal material with a weight ratio of the actual extraction amount of the shining wintersweet to the effective fractions being 1.0-2.6:0.5-3.5, thus the effective fractions of the shining wintersweet leaf are obtained. A preparation of the effective fractions of the shining wintersweet can be made into granules, soft capsules, capsules, drop pills, tablets, compound capsules, dispersible tablets, etc. In the invention, the preparation of the shining wintersweet is deeply developed, which ensures that the preparation is rich in active ingredients, has definite effective ingredients, obvious pharmacological action and significant improvement of drug action. Besides, the preparation has stable performance and controllable quality, is safe and reliable, has less dosage, and is favorable for transportation and storage of the medicine as well as for patients to take.

The invention relates to a double coptis for injection as a veterinary herbal medicine compound preparation and a preparation technique as well as an application thereof. The compound preparation is made from the following parts of medicines by weight: 1250 portions to 3750 portions of honeysuckle, 1250 portions to 3750 portions of scutellaria and 2500 portions to 7500 portions of forsythia. Sustained release accessories contain 200 portions of hydroxypropyl methylcellulose and 100 portions of sodium carboxymethylcellulose. The containing of sustained release accessories can reduce injection times for large animals and the stress response of large animals. The veterinary herbal injection preparation has the functions of antiviral, antibacterial, anti-inflammatory and antipyretic analgesic effects, as well as improving immunity and the like, and can be applied to epidemic diarrhea, transmissible gastroenteritis, swine paratyphoid, septicemia caused by various diseases, cough, dyspnea, skin cyanosis, arthrocele, lameness, swine reproduction and respiratory disturbance syndrome and cow mastitis caused by streptococcosis, haemophilus parasuis infection, contagious pleuropneumonia, swine lung plague in veterinarian clinical practice.

The invention discloses a drug compound for preventing and curing diabetes mellitus, which at least comprises two components including Timosaponin B-II and berberine. Preventing and curing effect can be improved by adding one or a plurality of components from mangiferin, Timosaponin A-III and Timosaponin B-III. The drug compound can also be compounded by anemarrhena extractive and golden cypress extractive, or can be directly extracted from anemarrhena and golden cypress. The drug compound has the advantages of obvious blood sugar reduction effect, and high effective component content, easy quality control. The preparation process of the drug compound is easy for industrialization, and can be applied as drugs to prevent and cure diabetes mellitus.

The invention aims to develop medicinal composition fat emulsion injection containing eucalyptol, limonene and alpha-pinene and a preparation method. The preparation comprises the following components in percentage by weight: 0.0128 to 0.0320 percent of eucalyptol, 0.0084 to 0.0210 percent of limonene, 0.0028 to 0.0070 percent of alpha-pinene, 10 to 30 percent of soybean oil for injection, 1.0 to 1.5 percent of yolk lecithin for injection or 0.8 to 1.5 percent of soybean phospholipids for injection, 2.0 to 2.5 percent of glycerol for injection, and water for injection added to 100 milliliters. The preparation method has the characteristics of strong controllability of production quality, and definite treatment effect of a product. The invention fills up the blank of the medicinal composition fat emulsion injection preparation containing the eucalyptol, the limonene and the alpha-pinene.

The invention discloses a prepared traditional Chinese medicinal preparation having anticancer reactivity, which is an extraction containing saponin prepared from Marsdenia tenacissima, a traditional Chinese medicinal Asclepiadaceae plant through refining. The invention also discloses the process for preparing the traditional Chinese medicinal preparation having anticancer reactivity and its use.

The invention provides application of a panaxadiol saponins fraction in preparing a medicine for preventing dermatitis and scar and a health-care cosmetic. The panaxadiol saponins fraction comprises the following main constituents: ginsenoside Rb1, ginsenoside Rb2, ginsenoside Rb3, ginsenoside Rc and ginsenoside Rd. The medicine or the cosmetic is prepared from active constituents in the single panaxadiol saponins fraction or/and other medicines together and a pharmaceutically acceptable or cosmetic acceptable carrier. The medicine or the cosmetic is prepared by utilizing raw materials: ginseng rhizome medicinal materials, American ginseng rhizome medicinal materials, ginseng stem leaf medicinal materials, American ginseng leaf medicinal materials and total extractives or total saponins of the ginseng rhizome medicinal materials, the American ginseng rhizome medicinal materials, the ginseng stem leaf medicinal materials and American ginseng leaf medicinal materials through a chromatographic separation and purification method combining macroporous resin column chromatography and octadecylsilane chemically bonded silica column chromatography. The scar can be prevented from forming while the tissue regeneration and repair are promoted by the medicine or the cosmetic. Compared with glucocorticoids, cellular immunity is integrally regulated, the drug action is stable after the medicine is suspended, and the drug action advantage is obvious. The medicine or the health-care cosmetic is highly safe. The structural formula of panaxadiol saponins is shown in the specification.

The effective Chinese medicine part composition has the functions of benefiting vital energy, nourishing Yin, etc. The effective Chinese medicine part composition features that it includes total ginsenoside, total ophiopogonin, volatile schisandra oil and total schisandra lignin.

The present invention discloses application of ganoderic acid T and ganoderic acid Me in preparation of inhibitor of tumor growth or proliferation. The internal and external tests show that ganoderic acid T and ganoderic acid Me have obvious action for inhibiting human tumor cell growth or proliferation, at the same time its toxicity for normal cell is low.

The invention relates to a composition containing arctiin or arctigenin and a preparation method thereof. The purity of the arctiin and the arctigenin is over 90 percent. The weight part of the arctiin is 50 to 99. The weight part of the arctigenin is 1 to 50. The invention has the function of treating and preventing diabetic cardiovascular. The arctiin or arctigenin is made pure to prepare the composition. The results of pharmacology, toxicology and clinical trial show that the arctiin or the arctigenin composition of the invention has the characteristic that the composition has good effect on treating diabetic retinopathy and little toxic and side effect.

The invention relates to a Chinese herbal medicine compound preparation for treating skin and mucous membrane disease. The Chinese herbal medicine compound preparation is prepared from the following raw materials: cortex moutan, polygonum chinense, radix salviae miltiorrhizae, herba lycopi, common dayflower herb, rhizoma smilacis glabrae, ramulus cinnamomi, caulis dendrobii officinalis, gorgon fruit and cortex cinnamomi; the ingredient of the Chinese herbal medicine compound preparation comprises a cortex moutan extract, a polygonum chinense extract, a radix salviae miltiorrhizae extract, a herba lycopi extract, a common dayflower herb extract, a rhizoma smilacis glabrae extract, a ramulus cinnamomi extract, a caulis dendrobii officinalis extract, a gorgon fruit extract and a cortex cinnamomi extract; and the effective ingredient of the cortex moutan extract is paeonol, the effective ingredient of the polygonum chinense extract is quercitrin, the effective ingredient of the radix salviae miltiorrhizae extract is tanshinone IIA, the effective ingredient of herba lycopi is ursolic acid, the effective ingredient of common dayflower herb is commelinin, the effective ingredient of rhizoma smilacis glabrae is astilbin, the effective ingredient of ramulus cinnamomi is cinnamaldehyde, the effective ingredient of caulis dendrobii officinalis is erianin, the effective ingredient of gorgon fruit is cyclo(profilum), and the effective ingredient of cortex cinnamomi is cinnamaldehyde.

The invention relates to a Chinese traditional medicine active extract, a preparation method thereof and an application thereof, particularly relates to an effective part extracted from a Chinese traditional medicine Qinglongyi, its preparation method and its application. The Qinglongyi active extract is prepared by the following steps of ethanol diacolation, reflux, ultrasonic extraction, CO2 supercritical extraction, ethanol precipitation, elution, interception, reflux, concentration, dryness and the like. According to the invention, the anticancer activity of the Qinglongyi effective part is taken as an index for screening the effective part of Qinglongyi, efficacy tests are carried out by using the extract with different contents, the result proves that an effective component in the Qinglongyi active extract for treating cancer is total naphthoquinone; the efficacy test result proves that an effective component for anti-inflammatory analgesic effect is total flavonoid, total tannin and polar micromolecules; a substrate for improving immune function is polysaccharide.

The invention relates to the novel use of pharmaceutical preparations in the field of pharmacy, more specifically the use of barrenwort flavones and barrenwort glycosides monomers as active components in preparing medicament for preventing and treating suppression. Pharmaceutical test shows that, the barrenwort flavones and barrenwort glycosides monomer can appreciably shorten rat's tail suspension time and forced swimming standby time, reverse the decrease of mouse sucrose consumption caused by CMS, suppress animal brain monoamines oxidation enzyme an and B, thus achieving the purpose of suppression resistance.

The invention discloses a human anti-rabies virus neutralizing antibody as well as the preparation method and the application thereof. The heavy chain variable region and the light chain variable region of the antibody respectively have an amino acid sequence represented by sequence 2 and sequence 4 in a sequence list, and the heavy chain variable region and the light chain variable region of a modified body of the antibody irrespectively have an amino acid sequence represented by sequence 8 and sequence 10 in the sequence list. The antibody is prepared according to the following steps: firstly, preparing a CDR region, a variable region, IgG section or the whole genes of the antibody by molecular biology or other methods; expressing in prokaryotic cells such as Escherichia coli, eukaryotic cells such as yeast, insect cells, plant cells or mammal cells such as CHO; and purifying to obtain the antibody. The antibody has the advantages of high specific neutralization activity, high affinity and no toxic and side effects, suits prevention and emergency treatment of rabies as well as detection of rabies virus, and has excellent application prospect.

The invention discloses new application of an extract of Chinese angelica and szechuan lovage rhizome composition to the preparation of a medicament for promoting ovary granular cell proliferation. Intensive study is performed on a large quantity of ancient and modern prescriptions and traditional Chinese medicine application data, traditional Chinese medicine resources are fully utilized according to a traditional Chinese medicine theory and the pathogenesis of ovarian functional disturbance and insufficient growth of ovary granular cells and a large number of pharmacological tests are performed based on the current researches of Chinese angelica and szechuan lovage rhizome, so that new application of the Chinese angelica and szechuan lovage rhizome to the treatment of ovarian functional disturbance and the promotion of ovary granular cell proliferation; moreover, the weight ratio of the Chinese angelica and szechuan lovage rhizome composition with the highest activity is screened through a large quantity of experiments. When clinically taken as a medicament for treating ovarian functional disturbance and promoting ovary granular cell proliferation, the extract has the advantages of good curative effect, definite active ingredient, small side effect, convenience of taking and the like.

The medicine composition for treating cardiac and cerebral vascular diseases has ligustilide and volatile grassleaved sweetflag rhizome oil in the weight ratio of 1 to 0.5-20 as effective medicinal components and contains also borneol and musk and pharmaceutically acceptable supplementary material. Test proves the synergistic effect between ligustilide and volatile grassleaved sweetflag rhizome oil as well as of borneol and musk in resisting cerebral ischemia reperfusion injury and resisting anoxia.

The invention discloses semen hoveniae extracts with a liver protection function and an extraction and separation method and application thereof. The extracts comprise, by mass, 10-99% of total flavone C-glycoside, wherein the main flavone C-glycoside comprises six kinds of flavone C-glycoside including vitexin 2''-O-beta-D-glucopyranoside, spinosin, poloretin-3', 5'-di-C-beta-D-glucopyranoside, 6'' '-acetyl spinosin, 6'' '-p- hydroxyl-cinnamoyl-spinosin and 6'' '- sinapoyl-spinosin. The total flavone C-glycoside is extracted from semen hoveniae and used for preventing and treating acute and chronic hepatitis and alcoholic liver disease; compositions at effective parts are accurate; toxicity is small; the pharmacological action is high, and a good medicine prospect is achieved. The extracts and acceptable agents on pharmacy are adopted to be prepared into various dosage forms through a conventional method, like tablets, pills, capsules and granules. The dosage is 200-800 mg/each person/day.

The invention discloses composite anti-fatigue beverage containing plant extracts. The beverage disclosed by the invention consists of salidroside, rhodiola rosavin, astragalus saponin, hawthorn flavone, caffeine, taurine, inositol, nicotinamide, lysine, vitamins, citric acid, cane sugar, juice and water according to a reasonable ratio. The anti-fatigue beverage disclosed by the invention has the effects of resisting fatigue and improving the immunity.