Medicament composition for curing diabetic cardiovascular pathological changes and method of preparing the same

A technology of diabetes and composition, applied in the field of composition for treating diabetic cardiovascular disease and its preparation field, can solve the problems of low purity of arctiside, unfavorable production quality control and improvement of drug effect, etc.
CN101278940AInactive Publication Date: 2008-10-08THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV
Publication Date
2008-10-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a composition containing arctiin or arctigenin and a preparation method thereof. The purity of the arctiin and the arctigenin is over 90 percent. The weight part of the arctiin is 50 to 99. The weight part of the arctigenin is 1 to 50. The invention has the function of treating and preventing diabetic cardiovascular. The arctiin or arctigenin is made pure to prepare the composition. The results of pharmacology, toxicology and clinical trial show that the arctiin or the arctigenin composition of the invention has the characteristic that the composition has good effect on treating diabetic retinopathy and little toxic and side effect.
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Description

technical field

[0001] The invention relates to a pharmaceutical composition with plant material extract as an active ingredient, in particular to a group of compositions for treating diabetic cardiovascular disease and a preparation method thereof. Background of the invention

[0002] At present, the incidence of diabetes in the world is about 4.6%, with a total of 200 million people. Its incidence rate is increasing year by year. It is estimated that by 2025, the incidence rate of diabetes will be about 5.4%, reaching 300 million people.

[0003] Diabetic cardiovascular complications are the most common and serious chronic complications of diabetic patients, such as atherosclerosis of large and medium arteries and microvascular lesions (diabetic nephropathy, diabetic retinopathy, and diabetic cerebrovascular dysfunction, etc.), which are the main causes of poor prognosis and leading cause of death. Diabetes can cause endothelial cell damage and insufficiency, leading to ...

Claims

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