98results about How to "Reliable efficacy" patented technology

One aspect of the present invention relates to a method of hormone replacement in mammals, which method comprises the oral administration of an estrogenic component and a progestogenic component to a mammal in an effective amount to prevent or treat symptoms of hypoestrogenism, wherein the estrogenic component is selected from the group consisting of substances represented by the above formula in which formula R₁, R₂, R₃, R₄ independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R₅, R₆, R₇ is a hydroxyl group; and no more than 3 of R₁, R₂, R₃, R₄ are hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. Another aspect of the invention concerns a pharmaceutical kit comprising oral dosage units that contain the aforementioned estrogenic component and a progestogenic component as well as an androgenic component.

An extract of mulberry twigs is dislcosed, which can be used to prepare the food or the medicine to cure hyperuricemia and gout diseases. The said extract is prepared from mulberry twigs through extracting in solvent (aqueous solution of alcohol, chloroform, acetone, etc) at 10-100 deg.C more than one time, mergint the liquid extracts, recovering solvent, regulating pH value to 7.5-9.5, centrifugal separation to obtain supernatant, regulating pH value to 4-6, deposition, water washing wand drying. Several other approaches for purifying it are also disclosed.

The invention provides a Chinese medicament for treating heart disease, which is prepared from the following raw material medicaments: Chinese angelica, white paeony root, danshen root, Chinese thorowax root, szechwon tangshen root, radix astragali seu hedysari, flowery knotweed root, cassia bark, amur corktree bark, silktree albizzia bark, lotus plumule, platycladi seed, medlar, donkey-hide glue, hawthorn fruit, costusroot, dendrobium, honeysuckle flower, weeping forsythiae capsule, root of straight ladybell, Siberian solomonseal rhizome, fluorite, barbed skullcap herb, eclipta, grassleaf sweelflag rhizome, thinleaf milkwort root-bark, mulberry, low lily bulb, Chinese magnoliavine fruit, spina data seed, bitter orange, fragrant solomonseal rhizome, tuber fleeceflower stem, semen nelumbinis, lotus stamen, Mongolian snakegourd root, mantis egg-case, Indian buead, pearl powder, dragon's bones, oyster shell, fennel fruit, tall gastrodia tuber, figwort root and nutgrass galingale rhizome. The Chinese medicament of the invention is reliable in potency, small in side effect, wide in application range and convenient for treatment; and the heart disease of patients is not easy to relapse after being cured and can be gradually cured if the patients continuously take the Chinese medicament.

A method of contraception in mammalian females, which method comprises the oral administration of an estrogenic component and a progestogenic component to a female of childbearing capability in an amount effective to inhibit ovulation, wherein the estrogenic component is selected from the group consisting of substances represented by the following formula (1)

in which R₁, R₂, R₃, R₄ independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R₅, R₆, R₇ is a hydroxyl group; and no more than 3 of R₁, R₂, R₃, R₄ are hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. Another aspect of the invention concerns a pharmaceutical kit comprising oral dosage units that contain the aforementioned estrogenic component and/or a progestogenic component.

The invention discloses health-care food for improving male prostatic diseases. The health-care food comprises components in percentage by weight as follows: 10%-20% of lycopene, 10%-30% of seal oil, 20%-40% of a morindaofficinalis extract, 3%-10% of beeswax and 10%-40% of pumpkin seed oil. The components have various effects and have synergistic interaction, the health-care food has the effects of preventing energy deficiency, hypofunction, prostatic hyperplasia, prostatic hyperplasia, prostatitis and the like, has the advantages of scientific composition, natural components, proper proportion, convenience in taking, reliable effects and avoidance of toxic and side effects, can be taken for a long time and is suitable for prevention and treatment of prostatic diseases for medium-elderly men.

The invention discloses a control method layer mining, control and testing of gas well. The method comprises the following steps: setting three production gas layers of a natural gas well as a gas layer A, a gas layer B and a gas layer C, mounting a direct reading intelligent gas well underground layering zonal pressure measuring device on each layer, packing the three production gas layers through a gas control underground packer, and ensuring that a ground intelligent control box gives an instruction to enable the direct reading intelligent gas well underground layering zonal pressure measuring devices of the gas layers A and C to be closed, open a communicating hole of the direct reading intelligent gas well underground layering zonal pressure measuring device of the gas layer B when the gas layer A is required to be closed, the gas layer B is required to perform production and the gas layer C is required to be closed, so as to enable natural gas of the gas layer B to be output to the ground through an oil pipe and to realize layer control; ensuring that a ground metering station can timely measure the gas output of a layer, so as to realize layer gas production; ensuring that the direct reading intelligent gas well underground layering zonal pressure measuring devices can record the production pressure difference and underground temperature at the same time, so as to realize layer testing. The gas layer A, the gas layer B and the gas layer C can be subjected to simultaneously gas production and testing.

The present invention refers to an optimized and defined method for isolation and preservation of precursor cells from human umbilical cord. Besides being reproducible and 100% reliable, in terms of the number of samples processed, the method results in a high and defined number of precursor cells, being the majority obtained after a single adhesion and expansion/multiplication phase ex vivo (thus granting cell phenotype), in a shorter time frame than what was previously described in the state-of-the-art. With this method, it is possible to obtain, in 9 days, after direct freezing of a cell fraction, and after one expansion/multiplication phase ex vivo (end of P0) of the majority of the cells, about 8.6(±0.1)×10⁵ cells/gram of processed umbilical cord. In turn, the characteristics of the cells allow, for example, after 35 days, obtaining an average of 7.7×10¹⁵ cells, with precursor phenotype, from 100% of processed umbilical cord samples. The method, because it is simple, robust and 100% reliable, can be performed under good manufacturing practices (GMP) in laboratories dedicated to cell therapy in humans. Furthermore, the method has applications in the pharmaceutical, cosmetic and biotechnology areas.

An adjustable soft palate support and an implantation method are provided. The adjustable soft palate support is a flat implant made of a material capable of being implanted into a human body for a long term, including a hard palate connecting end and a support. The support is a flat implant capable of being inserted into a soft palate, and is connected to the hard palate connecting end. The hard palate connecting end includes a connecting structure and an adjustment mechanism connected to a hard palate. The connecting structure on the hard palate connecting end is configured to fix the support to the hard palate, and the adjustment mechanism on the hard palate connecting end is configured to control the movement or a curvature of the support or a lifting degree of the soft palate. Since the hard palate connecting end is fixed to the hard palate, and the support is implanted into a muscular layer of the soft palate, a relaxed and collapsed soft palate and a root portion of a tongue are lifted by using the hard palate as a supporting point. Since swallowing occurs frequently in a non-sleep state, the adjustment mechanism is set to be in an on state, so that the support implanted into the soft palate can move with the natural swinging of the soft palate, so as to reduce interference with swallowing; and before sleep, a control key of the adjustment mechanism on the hard palate is pushed with a finger or an apex of tongue to set the adjustment mechanism to be in an off state, so that the support implanted into the soft palate can lift the soft palate, and change a central axis of the soft palate during natural swinging by lifting the soft palate towards the tongue root, so as to enlarge an airway of a pharynx during breathing, thereby achieving the objectives of treating snoring and obstructive sleep apnea/hypopnea syndrome (OSAHS).

The invention provides a traditional Chinese medicine for treating diabetes, which is prepared by the following raw material drugs in portion by weight: 8 to 20 portions of radix codonopsitis, 12 to 36 portions of hoantchy root, 8 to 20 portions of Chinese yam, 12 to 28 portions of root of rehmannia, 12 to 26 portions of prepared rhizome of rehmannia, 8 to 18 portions of Gordon euryale seed, 4 to 12 portions of fragrant solomonseal rhizome, 6 to 18 portions of poria, 6 to 18 portions of Dendrobium nobile, 8 to 22 portions of dwarf lilyturf turber, 3 to 12 portions of sea dragon, 2 to 10 portions of cordyceps, 6 to 22 portions of kudzuvine root, 6 to 18 portions of milkwort, 5 to 18 portions of shelled cedar seed, 5 to 18 portions of jujube seed, 3 to 15 portions of bitter orange, and 3 to 15 portions of licorice. The traditional Chinese medicine has the efficacies of strengthening the spleen and reinforcing the kidney, nourishing Yin and tonifying Yang, nourishing the heart and tonifying Qi, and harmonizing five internal organs, has remarkable effect of preventing and treating heavy head, enervation, anaesthesia and complications caused by diabetes, has the advantages of reliable medicine effect, little side effect, wide adaptation diseases, convenient treatment, no easy relapse after healing and continuous use, and can gradually heal diabetes.

The present invention relates to a Rehmannia glutinasa Libosch. extract for reducing blood glucose and lipid levels and treating hematologic diseases such as leukemia, and methods for preparing the same. The extract is prepared by subjecting fresh Rehmannia glutinasa Libosch. to flux extraction, concentrating the resultant extract, dissolving the concentrated extract with water, loading the obtained solution on a column packed with macroporous adsorption resins, eluting the column with ethanol, concentrating and drying the eluate. The extract can be made into clinically acceptable forms of dosage by pharmaceutically conventional measures, including capsule, tablet, pill, granule, dropping pill and so on. The extract is stable and has catalpol content up to 90-98%. The preparing method is simple to operate and applicable to industrial-scale production.

The present invention relates to a kind of medicine for treating hepatitis and its preparation process, and is especially a kind of injection and its preparation process. The medicine is compounded with the extract of six kinds of Chinese medicinal materials, including pig bile powder, goat horn, skullcap root, cape jasmine, honeysuckle and isatis root. The injection is compounded via adding injection water to the medicine, and medicine may be also prepared into other preparation forms. The medicine may be used in treating acute icterohepatitis, viral hepatitis, chronic hepatitis B, hepatitis C, hepatocirrhosis, and other liver diseases. The medicine has obvious curative effect.

The invention relates to Chinese medicine and a manufacturing method of the Chinese medicine, and belongs to the field of a Chinese medicine pillow core and the manufacturing method of the Chinese medicine pillow core. The Chinese medicine pillow core for treating the cervical spondylosis is characterized by comprising, by weight, 5-13 parts of Angelica sinensis, 3-12 parts of lumbricus, 6-15 parts of rhizoma drynariae, 3-12 parts of prunella vulgaris, 8-15 parts of Ligusticum wallichii, 7-12 parts of cassia twigs, 8-12 parts of radix aconiti, 5-8 parts of ephedra, 6-12 parts of carthamus tinctorius, 8-12 parts of Caulis Spatholobi, 8-10 parts of Agrimonia pilosa, 3-7 parts of gastrodia elata, 6-13 parts of myrrh, 10-15 parts of angelica dahurica, 3-10 parts of mint, and 12-18 parts of Sappan Wood. According to the Chinese medicine pillow core, skin absorption is used for treating patients with the cervical spondylosis, treatment is carried out when people sleep, and additional treatment time is not needed. The Chinese medicine pillow core is simple and convenient to use and suitable for being used for a long time, and does not have any toxic and side effect. The Chinese medicine formula of the Chinese medicine pillow core has good medicine permeability, raw materials are compatible mutually, bring out the best in each other and can relax the muscles, stimulate the blood circulation and relieve the pain, and the therapeutic effect is precise and remarkable.

The invention relates to the field of the pharmaceutical preparation, in particular to a cyanocobalamine and adenosine combined pharmaceutical preparation, and comprises an oral solid preparation, injection, a freeze-dried preparation for injection and a preparation method thereof. Each unit of pharmaceutical preparation of the invention comprises 0.05-5.0mg of cyanocobalamine and 0.05-5.0mg of adenosine, wherein the weight ratio of the cyanocobalamine and the adenosine is 1:10-10:1, and the preferential weight ratio is 1:5-5:1.

A Chinese medicine for treating acute or chronic pharyngolaryngitis, pharyngalgia, pharyngoxerosis, etc is prepared from 5 Chinese-medicinal materials including honeysuckle flower, myrobalan seed, scrophularia root, asarum herb, etc.

The invention belongs to the field of Chinese veterinary medicine, and specifically relates to a traditional Chinese medicine composition for preventing and curing avian gout. The traditional Chinesemedicine composition comprises, in parts by weight, 1.5-2 parts of rhizoma smilacis glabrae, 1-2 parts of flos sophorae, 1-2 parts of lygodium japonicum, 1-1.5 parts of akebia stem, 0.5-1 part of coptis chinensis, 1-2 parts of liquorice, 0.5-1 part of radix astragali, 0.5-1 part of hawthorn, and 0.5-1 part of medicated leaven. The traditional Chinese medicine composition has the beneficial effects: 1, the rhizoma smilacis glabrae and the flos sophorae having good inhibition effect on xanthine oxidase are selected and can effectively inhibit generation of uric acid; 2, the traditional Chinese medicine composition is a pure traditional Chinese medicine preparation, is easy to absorb, has remarkable effect on treating avian gout, and has reliable effect, high safety and no drug residue; and 3, the traditional Chinese medicine composition is preferably a powder form, is convenient to manufacture, storage and use, and can be promoted and applied.

The invention relates to a preparation method of a Chinese traditional medical preparation, namely a preparation technique for producing Kangfuling suppositories, comprising the following steps of crushing 19.2g of borneol and 27.4g of catechu for later use; adding 95% of ethanol to extract 674g of crude powder of rhubarb under reflux for two times, 1.5 hours each time, recycling the ethanol, concentrating under vacuum, drying under vacuum, and crushing for later use; soaking 274g of redroot gromwell with 657.5ml of balm for 72 hours, filtering out the redroot gromwell, adding balm to 493.2ml when the balm is less than 493.2ml after being heated, adding 330g of paraffin and 110g of beeswax, stirring to synthesize into sorbitan fatty acid ester, heating to 45 DEG C, stirring, adding fine powder of borneol and catechu and rhubarb powdered extract, uniformly stirring, encapsulating, 2.5g each, preparing into 1,000 suppositories. The technique is environment-friendly and meets requirements of GMP standard; the suppositories have reliable curative effect and are more conveniently used.

The invention discloses a fermented traditional Chinese medicine capable of improving production performance of poultry. The fermented traditional Chinese medicine is prepared from Radix Astragali seuHedysari, codonopsis pilosula, bighead atractylodes rhizome, poria cocos, rhizoma chuanxiong, herba leonuri, glossy privet fruit, cortex acanthopanacis, liquorice root and Chinese angelica which arefermented by specific probiotics. According to the fermented traditional Chinese medicine, the laying rate, the egg weight, the hatching egg yield, the fertilization rate, the hatching rate and the like of the poultry can be significantly increased, and the feed to gain ratio and the soft-shelled egg breaking rate are significantly decreased. The preparation method of the fermented traditional Chinese medicine comprises the steps: all the traditional Chinese medicine components are inoculated with strains and then subjected to solid-state fermentation. A process is simple, and industrially production is easy.

The invention discloses gallbladder-soothing capsules. The gallbladder-soothing capsules are prepared by the following steps of: properly extracting rhubarb, giant knotweed, dried green orange peel, cogongrass rhizome, dried old orange peel, curcuma aromatica and hawthorn serving as raw materials, adding auxiliary materials, mixing uniformly and packaging with capsule shells. The gallbladder-soothing capsules have the effects of soothing the liver, benefiting the gallbladder, clearing away heat and promoting excretion; and the gallbladder-soothing capsules have the advantages of reliable drug efficacy, controllable quality and prolonged quality guarantee period and high curative effect.

The invention provides a medicine for curing tumor and a method for preparing the medicine. The medicine is made from the following raw materials according to the weight propotion: nux vomica of 1 to 3 parts, semen momordicae of 3 to 5 parts, brassica alba boiss of 1 to 5 parts, red castor bean of 3 to 7 parts, Iphigenia indica of 0.8 to 1.5 parts, common burreed tuber of 1 to 3 parts, rhizoma zedoariae of 2 to 5 parts, frankincense of 1 to 3 parts, myrrh of 1 to 4 parts, safflowers of 1 to 3 parts, peach seed of 1 to 3 parts, white alum of 1 to 3 parts, hemlock parsley of 1 to 3 parts and dried body of ground beetle of 1 to 3 parts. The raw materials are crushed into powder and added with wine or water to be made into paste which is then used for covering the tumor or corresponding points. The medicine of the invention has reliable effect, small side effect, wide application and convenient treatment, and the syst and knub can be gradually cured through continous application and are not likely to recur after being cured.