74 results about "Muscular layer" patented technology

The present invention aims to measure easily and accurately information about the panniculus (such as fatty layer, muscular layer, osseous layer) in the depth direction below the surface of a living body. To achieve this object, in an embodiment of the invention, a pair of current-carrying electrodes 1a, 1b and a pair of measuring electrodes 2a, 2b are rectilinearly arranged on the surface of the living body so that the measuring electrode 2a within a small area is placed very close to the current-carrying electrode 1a with small area. While constant current from a radio frequency current source 3 flows between the current-carrying electrodes 1a, 1b, the voltage between the measuring electrodes 2a, 2b is measured by the detector 4. The potential of the measuring electrode 2a is almost equal to the potential at the contact position P3 of the current-carrying electrode 1a, and the potential of the measuring electrode 2b is almost equal to the potential at the deepest position P1 of the vertical part 5c inside the living body 5. Therefore, the potential difference between the upper and lower ends of the vertical part 5c. The bioelectical impedance Zv of the vertical part 5c is calculated from the potential difference and the current i.

Methods and devices for use in tissue approximation and fixation are described herein. The present invention provides, in part, methods and devices for acquiring tissue folds in a circumferential configuration within a hollow body organ, e.g., a stomach, positioning the tissue folds for affixing within a fixation zone of the stomach, preferably to create a pouch or partition below the esophagus, and fastening the tissue folds such that a tissue ring, or stomas, forms excluding the pouch from the greater stomach cavity. The present invention further provides devices for performing a transoral, endoscopic hollow organ division, including a tissue acquisition device capable of acquiring the desired tissue circumferentially, and a fixation mechanism to secure the muscular layers of the acquired tissue such that the desired healing response is achieved.

The present invention is directed to a method for providing an access point for laparoscopic intra-abdominal surgery disconnected from the area of the ultimate intra-abdominal procedure. This method allows for the necessary skin incision(s) for insertion of the laparoscopic equipment to occur in a favorable area, transverse below one or more tissue layers to a secondary insertion point in a favorable area, and for the further insertion of the laparoscopic equipment. Favorable area selection affords the surgeon the ability, for example, to select a region of the patient that may result in a less obvious scar of the cutaneous layer of the abdominal wall for the first incision and optimal location in regards to mechanical stability of the muscular layer of the abdominal wall for the second incision. The invention further includes devices for performing such described method.

The invention relates to the technical field of medicines and in particular relates to a traditional Chinese medicine composition with effects of clearing heat, relieving pain and eliminating tumors. The formula consists of the following main components in parts by weight: 3-5 parts of alga, 2-4 parts of albumen powder, 1-3 parts of pseudo-ginseng and 0.05-1.5 parts of musk. A product prepared from the medicine composition has the functions that pain of cancer patients can be relieved, injuries on human body, physiological functions and immune systems of patients are avoided, the possibility of diffusion and metastasis caused by cancer cell infiltrated muscular layer, blood vessels and lymph-vessels is eliminated, the drug resistance and tolerance of cancer cells are avoided, the toxic and side effects of the medicine are reduced, the processes of generating body hormones, subsequently maintaining the immunity, realizing aerobic transfer of nutrient substances and generating and intensifying hemoglobin and blood platelets in the treatment process and after healing are ensured, and the cancer cure rate and remission rate are further increased.

An adjustable soft palate support and an implantation method are provided. The adjustable soft palate support is a flat implant made of a material capable of being implanted into a human body for a long term, including a hard palate connecting end and a support. The support is a flat implant capable of being inserted into a soft palate, and is connected to the hard palate connecting end. The hard palate connecting end includes a connecting structure and an adjustment mechanism connected to a hard palate. The connecting structure on the hard palate connecting end is configured to fix the support to the hard palate, and the adjustment mechanism on the hard palate connecting end is configured to control the movement or a curvature of the support or a lifting degree of the soft palate. Since the hard palate connecting end is fixed to the hard palate, and the support is implanted into a muscular layer of the soft palate, a relaxed and collapsed soft palate and a root portion of a tongue are lifted by using the hard palate as a supporting point. Since swallowing occurs frequently in a non-sleep state, the adjustment mechanism is set to be in an on state, so that the support implanted into the soft palate can move with the natural swinging of the soft palate, so as to reduce interference with swallowing; and before sleep, a control key of the adjustment mechanism on the hard palate is pushed with a finger or an apex of tongue to set the adjustment mechanism to be in an off state, so that the support implanted into the soft palate can lift the soft palate, and change a central axis of the soft palate during natural swinging by lifting the soft palate towards the tongue root, so as to enlarge an airway of a pharynx during breathing, thereby achieving the objectives of treating snoring and obstructive sleep apnea/hypopnea syndrome (OSAHS).

The invention relates to the field of motion emulation human body models, in particular to a Chinese kungfu engineering person. The engineering person adopts 50% of human body basic characteristics of a Chinese adult, and is 170cm in height, and 68.4kg in weight. A main body part of the Chinese kungfu test engineering person is divided into a head part, a neck part, a breast part, a waist part, a triangular support frame, a hydraulic height adjustment device and a base. A trunk part of the Chinese kungfu test engineering person consists of five layers from inside out: an organ inner sensor, mechanical equivalent force transmission filling sponge, mechanical equivalent transmission filling rubber, an aluminum alloy skeleton, and external muscular layer imitation silica gel; the engineering person aims at simulating a human body physiological structure, improving the data precision of dummy striking, and providing a good foundation for the later injury evaluation. The engineering person has the following characteristics that: 1, stressed states of various organs of a human body are measured; 2, mechanical characteristics of a trunk are simulated, and 3, a sign of a Chinese is adopted to facilitate a research into Chinese traumatology.

The invention belongs to the field of high polymer materials and medical equipment, and particularly relates to a formula and a preparation technology of a submucosal injection sodium hyaluronate solution for an endoscope. According to the formula of the sodium hyaluronate solution, the sodium hyaluronate solution is prepared from sodium hyaluronate, sodium chloride, sodium hydrogen phosphate, sodium dihydrogen phosphate, methylene blue and water for injection. The preparation technology of the sodium hyaluronate solution includes the steps that firstly, sodium chloride is stirred and dissolved in a burdening tank, then sodium hyaluronate is added, temperature is raised to 40 DEG C, and stirring is performed; sodium hydrogen phosphate and sodium dihydrogen phosphate are sequentially added in, and stirring continues; secondly, the pH value of material liquid is measured; the pH value of the material liquid is adjusted to reach 7.0-8.0; thirdly, methylene blue is added and stirred, water is supplemented, and volume is metered; fourthly, filtering is performed through a microfiltration membrane ; fifthly, the mixture is encapsulated in an ampoule or a glass bottle and sterilized with steam at the temperature of 121 DEG C for 15 min, and the submucosal injection sodium hyaluronate solution is obtained. The sodium hyaluronate solution is used for endoscopic submucosal dissection (ESD) and is injected below a gastrointestinal mucous membrane, lesions can be fully swelled, a submucosal liquid cushion is formed, a submucosa and a muscular layer can be effectively separated, and bleeding, perforation and other complications can be reduced while electroexcision is facilitated.

The invention discloses a Chinese medicinal composition for thoroughly eliminating hysteromyoma. The Chinese medicinal composition is prepared from the following medicaments: radix salviae miltiorrhizae, lotus plumule, notoginseng, safflower, phellinus and basidiocarp are used as monarch medicaments; barbed skullcap herb, prunella, liquorice, Chinese sage herb, leech and cordyceps are used as ministerial medicaments; radix scrophulariae, giant knotweed, Chinese rose flower, small-fruited rose fruit, faeces togopteri and olibanum are used as adjuvant medicaments; and gleditsia thorn, arrowhead leaf, purple senecio, rhizoma bolbostematis, nidus vespae and muskiness are used as conducting medicaments. According to the combination of ancient Chinese medicine theory and modern medicine, through repeated medicinal pharmacological experiment and medicament combination experiment, starting with adjusting self disease-resistant function of the human body, the vital qi is harmonious and acts in the body; the Chinese medicinal composition fully stresses the treatment principles of activating blood and removing stasis; the Chinese medicament effectively adjusts incretion and reduces abnormal secretion of estrogen through oral taking so that the estrogen achieves physiological equilibrium and the inflammation on the middle wall layer of the uterus can quickly disappear; the proliferative endometrium improves the circulation, the simple obesity of a muscular layer gradually disappears, and the hard connective tissue becomes soft; therefore, the Chinese medicinal composition plays the role in treatment for regulating menses, stanching, relieving pain, diminishing inflammation and recovering ovary function, and prevents the occurrence of canceration.

The invention relates to an anti-aging skin care product and particularly discloses a stem cell face cream and a preparation method thereof. The face cream includes the following components: 1) a group A: 1-3% of cetyl alcohol, 0.2-2% of octadecanol, 5-15% of squalane, 1-3% of stearic acid, 0.2-2% of glycerin monostearate, 1-3% of Vaseline and 5-15% of wool fat; and 2) a group B: 5-15% of stem cell extract, 0.2-2% of silk peptide, 1-3% of collagen, 2-7% of glycerin, 0.2-0.7% of lactic acid, 0.2-2% of hyaluronic acid and 0.2-2% of a preservative. All the components are added with deionized water to 100%. The preparation method includes the steps of (1) mixing the components in the group A, heating the components to 70-75 DEG C; (2) heating the deionized water to 70-75 DEG C; (3) adding the group A to the deionized water, mixing the components uniformly, and stirring the mixture and decreasing the temperature; and (4) when the temperature is reduced to lower than 40 DEG C, adding the components in the group B and mixing the components uniformly. The stem cell face cream has excellent effects of stimulating muscular layer to generate fibroblast and skin proteins, thereby improving compactness and elasticity of skin.

The invention provides a preparation method of a trachea substitute. The preparation method comprises the following steps: eliminating antigens of an animal-derived tracheal tissue; compounding vascular endothelial growth factors (VEGF) with the outer wall of the trachea substitute; and compounding epidermal growth factors (EGF) with the inner wall of the substitute, wherein antigen elimination is carried out on a cartilage layer on the outer wall of a trachea and a lower muscular layer of a mucous layer on the inner wall of the trachea. The trachea substitute prepared by the method is derived from the animal tracheal tissue, has a specific C-shaped cartilaginous ring structure of a natural trachea, is formed by connecting compact connective tissues, has elasticity, can extend and contract longitudinally, and can moderately expand when gas passes through the substitute; and the prepared trachea substitute can keep the trachea unobstructed for a long time after transplantation, can notcollapse, and has good integration effect with a host without obvious rejection reaction. The preparation method has the advantages of simpleness, wide raw material source and low cost; and the medical cost can be reduced and the economic burden of patients can be lightened by means of large-scale industrial production.

The invention discloses a traditional Chinese medicine preparation for treating hysteromyoma, prepared from the following raw traditional Chinese medicines in parts by weight: 1-5 parts of pangolin scales, 1-5 parts of common burreed rhizome, 1-5 parts of zedoary root, 1-5 parts of seaweed, 1-5 parts of laminaria japonica, 1-5 parts of paris polyphylla, 1-5 parts of peach kernel and 1-5 parts of semen litchi. The invention has the effects of promoting blood circulation, removing blood stasis, resolving static blood, clearing away heat and toxic materials, dispersing and rectifying depressed liver-energy and relieving pains, has the advantages of good efficacy, fast effect, short treatment course, little side effect and the like for treating the hysteromyoma and is a first choice for treating diseases such as the hysteromyoma, ovarian cyst, endometriosis, hyperplasia of mammary glands, chronic pelvic inflammatory mass and the like. The invention can improve blood circulation of hyperplastic endometrium within a short period to enable simple hypertrophy of a muscular layer to gradually disappear and enable hyperplastic connective tissues to be gradually softened, and therefore, myoma can be fundamentally softened and reduced as well as can be finally and completely absorbed to disappear, thereby reaching the purpose of complete rehabilitation.

The invention discloses a preparation method of an SIS tissue repair material and application of the preparation method. The preparation method of the SIS tissue repair material is characterized by comprising the following steps that 1, a small intestine is taken, a serosa layer, a mucosal layer and a muscular layer of jejunum are scraped away, and after the treated small intestine is cleaned with deionized water and cut off, small intestinal submucosa is obtained; 2, degreasing is conducted, the small intestinal submucosa obtained in the first step is put into a percolation tube, percolate with the weight 3-5 times of that of the small intestinal submucosa is added, soaking is conducted for at least 6 h, after soaking is completed, percolation is conducted, and percolate with the weight 20-30 times of that of the small intestinal submucosa is added, wherein the percolation speed is 1-2 ml/min, and the percolate is a mixed solution of ethyl alcohol and surfactant. According to the preparation method of the SIS tissue repair material and the application of the preparation method, the preparation method is free of toxicity and environmentally friendly, and the SIS repair capacity is high.

One or more tissue bulking devices are implanted to bulk a structure within a patient. The tissue bulking devices may be implanted between the structure and an adventitial layer that at least partially covers the structure, or within the adventitial layer. In some embodiments, the structure is a luminal wall that defines an inner lumen, and the bulking devices are implanted endoscopically via the lumen. In such embodiments, the tissue bulking devices may be implanted between a muscular layer of the luminal wall and an adventitial layer that at least partially covers the luminal wall, or within the adventitial layer. In exemplary embodiments, the luminal wall is the wall of the esophagus of the patient, and the tissue bulking devices are implanted proximate to the lower esophageal sphincter (LES) of the patient to treat gastroesophageal reflux disease (GERD).

The invention discloses an endoscopic submucosal tunnel support which is characterized by comprising a head, a framework, an insulating layer, a tail, a recycling wire, an ejector rod, a sheath, a sheath handle and an ejector rod handle. A support body comprises the head, the framework, the insulating layer and the tail; the recycling wire penetrates thread gaps, which are close to the tail, of the framework; a conveyor comprises the ejector rod, the sheath, the sheath handle and the ejector rod handle; the ejector rod is positioned in the sheath and can axially move; the support body is preliminarily compressed and gripped in the sheath and can be completely pulled away from the sheath after being released, and the original spatial stereoscopic geometric shape of the support body can be restored; the recycling wire can be hooked, dragged and pulled, so that the support body can be withdrawn. The endoscopic submucosal tunnel support has the advantages that tunnels can be effectively supported by the endoscopic submucosal tunnel support when tunnel walls are excised during endoscopic submucosal dissection, accordingly, complications such as perforation and inherent muscular layer injury can be reduced, and the excision efficiency can be improved.

The invention relates to a soft tissue repair material and a method for preparing the same, and belongs to the technical field of biomedical material processing. The method includes steps of 1), removing small intestine mucous membranes, muscular layers and serous membranes on small intestine tissues of mammals and carrying out washing by the aid of sterile buffer solution with antibiotics by 3-5times to obtain washed lower-layer tissues of the small intestine mucous membranes; 2), clipping the lower-layer tissues to obtain sections, and splitting and spreading the sections along median linesto obtain pretreated lower-layer tissues of the small intestine mucous membranes; 3), placing the pretreated lower-layer tissues in sterile buffer solution with surfactants and nuclease and carryingout oscillation treatment at the temperatures of 37 DEG C for 1-4 h to obtain acellular lower-layer tissues of the small intestine mucous membranes; 4), carrying out oscillation cleaning, cutting anddrying to obtain dried central basement membranes; 5), carrying out irradiation sterilization to obtain the soft tissue repair material. The soft tissue repair material and the method have the advantage that the safe and effective soft tissue repair material with excellent bioactivity and biocompatibility can be prepared by the aid of the method.

The invention discloses a curved hemostatic forceps for conveniently placing an intrathoracic drain. The curved hemostatic forceps conveniently guides the intrathoracic drain into the thoracic cavitysmoothly, avoids excessive force or repeatedly using the hemostatic forceps for exploration, alleviates the sufferings of patients, and improves operation efficiency. The hemostatic forceps consists of grip rings, a buckle, a forceps handle, an axial ring and forceps leaves. Alveolus bed surfaces of two forceps leaves are provided with symmetrical concave surfaces, the concave surfaces are of semiellipse shape along cross sections of the forceps leaves, the concave surfaces of the two forceps leaves form a tubular structure with the cross section of oval shape when the hemostatic forceps is closed, and a tubular head is of conical shape and points at the front end of the forceps leaves; in such a way, a clamped cylindrical intrathoracic drain can slightly deform, which is favorable for exact clamping. Insection at other part of the alveolus bed is transverse insection, and insection at the concave surfaces part is vertical insection along vertical axis of the forceps leaves, which caneffectively clamp the intrathoracic drain tightly, and does not coarsen and damage the smooth surface of the intrathoracic drain. The head of the forceps can support the chest-wall muscular layer andparietal pleura, guide the orifice of the intrathoracid drain clamped by the forceps leaves into the thoracic cavity smoothly, and then the forceps is loosened, and leaves the thoracic cavity. The conical head part of the tubular structure can exactly clamp intrathoracic drains of different diameters, and avoid bringing out the intrathoracic drains when the hemostatic forceps is removed.

The invention relates to a traditional Chinese medicine formula for treating chronic proctitis. Proctitis is caused by careless diets, such as excessive drinking and overeating of strong excitant food, inappropriate long-term taking of weight losing medicament, excessive corrosive medicament in anus and bacteria infection. A light patient only has mucosa inflammation, and a severe patient has inflammations involving submucosa, muscular layer even rectum surrounding tissues; sometimes, part of the rectum mucosa is inflammatory, and sometimes the whole rectum mucosa or even colon mucosa are inflammatory. Proctitis is always seen in weak physique and resistance and after diseases of heart, lung, liver and gastrointestinal tract, respiratory tract infection, infectious disease; and constipation, diarrhoea, hemorrhoid, anorectal prolapse, anal fistula, polyposis, anorectal stenosis, rectum tumour, rectum damage and foreign matter all can cause proctitis. Severe patients need to be treated immediately. Prior proctitis treatment method is no more than a final operation, which causes huge pains in patient body and energy.

The invention relates to the field of lauromacrogol injection drug application, and discloses application of lauromacrogol injection as a drug for curing cesarean scar pregnancy. The drug is applied according to the following steps: step (1), a focus scope, a muscular layer thickness and the blood supply situation of a focus location are determined by ultrasound contrast; step (2), the vagina is conventionally disinfected and a towel is spread at a lithotomy position of a patient; step (3), under ultrasonic guidance, the lauromacrogol injection is injected at a peripheral muscular layer of a gestational sac and around the gestational sac, until annular or flaky reinforcement of the gestational sac is seen under ultrasound and peripheral blood is sparse, wherein the specification of the lauromacrogol injection is that each 10ml of injection contains 100mg of lauromacrogol. According to the application of the lauromacrogol injection as the drug for curing cesarean scar pregnancy, the lauromacrogol injection is adhered to the inside of a vessel at the injection site, thus prompting a fibrosis strip to replace the pathological vessel, resulting in permanent occlusion of the vessel around the gestational sac, interdicting an open vessel at the pathological location, and greatly reducing bleeding risk in induced abortion operation.

The invention belongs to the technical field of medical preparations of inorganic compounds containing ammonia, in particular to a construction method of a feces transplantation experiment piglet model, and the method is obtained by performing feces bacteria transplantation on a sterile newborn piglet. The method of the invention avoids the treatment of antibiotics or other sterilization drugs, the constructed fecal bacteria transplantation pig model has good effect with no drug residue, and the function of donor flora can be reflected more truly and reliably; the expression level of tight junction protein ZO-1 and Occludin in the empty intestine of the piglet can be improved; the development of muscular layer and gland of the intestinal wall of the piglet can be promoted; and the contentof various volatile short-chain fatty acids such as acetic acid, n-propionic acid, isobutyric acid, n-butyric acid, isovaleric acid, n-valeric acid and the like in intestinal tracts of the piglet is improved.

The invention provides a method for preparing a natural tubular small intestine acellular matrix membrane and belongs to the technical field of medical biological materials. The method comprises the following steps: cleaning small intestines cut from animals; adding the cleaned small intestines into a closed container, rapidly freezing in liquid nitrogen at the temperature of 80 DEG C below zero,taking out within half an hour, unfreezing, sleeving on an annular tubular scaffold, destroying the serosa by scissors, cutting off the serosa of the small intestines, scraping the destroyed serosa ofthe small intestines by organic glass, turning over the small intestines, scraping the mucous layer, submucosa and muscular layer of the small intestines, and removing the basal cells of the small intestines, thereby obtaining the single-layer tubular small intestine acellular matrix membrane; and performing freeze-dried seal and sterilizing preservation on the obtained single-layer and multilayer tubular small intestine acellular matrix membranes, thereby obtaining the natural tubular small intestine acellular matrix membranes of different thicknesses. The preparation method disclosed by theinvention is simple, and the prepared small intestine acellular matrix membrane is natural tubular.

The invention relates to application of deer-horn glue particles in preparing a drug for treating perimenopausal syndrome, and the drug use problem in treating the perimenopausal syndrome can be effectively solved. A method is that the deer-horn glue particles are prepared from 18-22g of deer-horn glue, 9-11g of Chinese yam fried with earth and 9-11g of jujubes, wherein water with the weight being 6-8 times the weight of the jujubes is added into the jujubes each time for decoction, decoction is performed twice, 30-40 minutes every time; two decoction solutions obtained by twice decoction are combined, and the mixture is concentrated until the concentration of a crude drug is 2g/ml, so that water-decocted jujube concentrated liquor is obtained; the deer-horn glue is molten by heat and is dissolved into the water-decocted jujube concentrated liquor to obtain mixed liquor; the Chinese yam fried with the earth is crushed into fine powder which passes through a 100-mesh sieve, the fine powder is dissolved into the mixed liquor to obtain a mixture, the mixture is dried under reduced pressure, the dried mixture is crushed into fine powder which passes through the 100-mesh sieve, and the fine powder is uniformly pelletized by use of alcohol with mass concentration being 90%, and is dried. According to the application, the deer-horn glue particles are rich in raw materials, simple in preparation method, have the effect of remarkably increasing the uterus index, change the states of endometrium, glands and muscular layers, and can be effectively used for preparing the drug for treating the perimenopausal syndrome.

The invention belongs to the field of biological medicines, relates to application of recombinant I-type humanized collagen in pelvic floor repair, and particularly provides application of the recombinant I-type humanized collagen in preparation of medicines for preventing and/or treating pelvic floor diseases (especially female pelvic floor dysfunction diseases). The recombinant I-type humanized collagen comprises n repetitions of a sequence as shown in SEQ ID No.1, n is an integer greater than or equal to 1, and when n is an integer greater than or equal to 2, the repetitions are directly connected. Experiments prove that the recombinant I-type humanized collagen can enhance the urine storage function of the bladder, improve the abdominal urine leakage point pressure, enhance the tension resistance of the vagina, thicken the intrinsic layer and the muscular layer of the vagina, increase the number of blood vessels and collagenous fibers of connective tissues of the intrinsic layer of the vagina, promote the synthesis of extracellular matrixes and promote the early adhesion of sacral ligament fibroblasts.

The present technology refers to medicine, namely hemostatic and wound healing agents, and can be used to stop bleeding of various severity, including venous, as well as to heal wounds and cuts obtained as a result of mechanical action on the epidermal and muscular layers of tissues. For this, a hemostatic agent containing an active gelling agent based on chitosan and/or its derivatives is used, characterized in that it contains chitosan, its salts and/or its derivatives in the form of a gel having a three-dimensional crosslinked structure as a polymer matrix and components of natural thrombus formation in the form of organic calcium compounds, organic acid and water coordinated on this matrix at a certain ratio of components.