242 results about "Ovarian cyst" patented technology

A method of local treatment of specific bone defects such as osteoporosis or bone cysts comprises the step of local administration of a formulation comprising a fusion peptide containing a first domain comprising PTH or BMP 2 or BMP 7, and a second domain comprising a covalently crosslinkable substrate domain; and a material suitable of forming a biodegradable matrix suitable for cellular growth or in-growth, wherein the fusion peptide is covalently linked to the matrix. In one embodiment, the matrix contains one or more contrast agents, and is preferably formed in the absence of a growth factor. The matrix may be used in the treatment of fluid-filled cysts such as Tarlov cysts, ovarian cysts, arachnoid cysts, aneurysmal bone cysts or hepatic cysts.

The invention discloses a novel traditional Chinese medicinal composition for treating ovarian cyst and a preparation method thereof. The traditional Chinese medicinal composition mainly comprises the following raw material medicines: pangolin scales, tribulus terrestris, spina gleditsiae, rhizoma sparganii, zedoary, leech, ground beeltle, aspongopus, dragon's blood, Chinese trumpet creeper, cowherb seed, suberect spatholobus stem, twotooth achyranthes root, motherwort herb, peach kernel, red flower, szechuan lovage rhizome, immature bitter orange, szechwan chinaberry fruit, pseudoginseng root, cyperus rotundus, Chinese eaglewood and the like. The traditional Chinese medicinal composition can be prepared into any common oral preparation according to the conventional traditional Chinese medicinal preparation method, can obviously improve abnormal menstruation caused by myoma of uterus, colporrhagia, increased leucorrhea, abdomen bilge pendant, abdominal pain, frequent micturition and urination disorder due to myoma pressure on the bladder, constipation and impeded defecating due to myoma pressure on the rectum and other symptoms, and has the advantages of obvious inhibition of cyst hyperplasia, prevention of cancerization, exact clinical curative effect, obvious curative effect, quick response, low cost, fundamentally no toxic or side effect, and the like.

The invention relates to a traditional Chinese medicine for curing ovarian cysts, which effectively solves the problems of high cost and poor curative effect of curing ovarian cysts and consists of two parts of internal medicine and external-application medicine, wherein the internal medicine is respectively prepared into decoction and powder from bupleurum, Rhizoma Pinellinae Praeparata, Indian buead, pedate pinallia jackinthepulpit rhizome, fried rhizoma atractylodis, common burreed rhizome, zedoary, astragalus root, sanguisuga, oyster shell, white mustard seed, thunberg fritillary, vinegar-unprocessed cyperus, angelica dahurica, seaweed, plantain seed, oriental waterplantain rhizome, cassia twigs, red paeony root, tree peony bark, processed rhizoma atractylodis macrocephalae, chicken's gizzard-membrane, processed peach seed, spreading hedyotis herb and campanumaea pilosula with the same prescription; the external-application medicine is prepared from common burreed rhizome, zedoary, salvia miltiorrhiza Bge, tree peony bark, common selfheal fruit-spike, cyathula officinalis kuan, fossilizid, astragalus root, processed rhizoma atractylodis alba, seaweed, motherwort herb, hovenia dulcis, cyrtomium rhizome, panax pseudoginseng, angelica sinensis, safflower, pinelliatuber, Indian buead, plantain seed, oriental waterplantain rhizome, cassia twigs, oyster shell, cowherb seed, cinnamon and turtle shell through the steps of mixing, crushing, loading in cloth bags, water leaching and evaporating. The invention has the advantages of scientific and reasonable compatibility, good curative effect, low cost and convenient use, and is an innovation in the medical field.

The invention discloses a traditional Chinese medicinal suppository for treating female chronic pelvic inflammation. The traditional Chinese medicinal suppository is prepared from the following raw materials in parts by weight: 10-20 parts of salviae miltiorrhizae, 10-20 parts of common andrographis herb, 10-20 parts of suberect spatholobus stem, 10-20 parts of motherwort, 10-20 parts of peach kernel, 10-20 parts of dahurian patrinia herb, 10-20 parts of sargentgloryvine stem, 10-20 parts of red peony root, 10-20 parts of Chinese trumpet creeper, 10-20 parts of sambucus williamsii hance, 10-20 parts of dandelion, 10-20 parts of scutellaria baicalensis, 10-20 parts of fructus kochiae, 10-20 parts of indigo naturalis, 10-20 parts of fructus cnidii, 10-20 parts of cortex mori radicis, 10-20 parts of dogwood, 10-20 parts of raspberry, 10-20 parts of white peony root, 10-20 parts of rhizoma cyperi, 10-20 parts of angelica root, 10-20 parts of sophora flavescens, and 10-20 parts of rhizoma smilacis glabrae. The traditional Chinese medicinal suppository has the effects of activating blood circulation to remove stasis, eliminating dampness and heat and directly reaching focus, and has a remarkable effect for treatment of chronic pelvic inflammation, chronic annexitis, ovarian cyst, elytritis and other common diseases, has the advantages of quick dissolution and quick drug release, and can achieve the aim of quickly relieving the symptom.

A genetic means of determining whether a female subject produces "pregnancy competent" oocytes is provided. The means comprises detecting the level of expression of one or more genes that are expressed at characteristic levels (upregulated or downregulated) in cumulus cells derived from pregnancy competent oocytes. This characteristic gene expression level, or pattern referred to herein as the "pregnancy signature", also can be used to identify subjects with underlying conditions that impair or prevent the development of a viable pregnancy, e.g., pre-menopausal condition, other hormonal dysfunction, ovarian dysfunction, ovarian cyst, cancer or other cell proliferation disorder, autoimmune disease and the like. Microarrays containing "pregnancy signature" genes or corresponding polypeptides provide another preferred aspect of the invention. Still further, the subject invention can be used to derive animal models, e.g., non-human primate animal models, for the evaluation of the efficacy of putative female fertility treatments.

A Chinese medicine in the form of dispersing tablet, dripping pill, soft-capsule, particle, micropill, or injection for treating breast nodule, breast lobule hyperplasia, ovarian cyst, hysterompoma, etc is prepared from 6 Chinese-medicinal materials including motherwort, spatholobus stem, China root, forsythia fruit, etc. Its preparing process and quality control method are also disclosed.

The invention discloses an intestinal obstruction removal pill, which comprises the following bulk medicaments: vinegar baked radix bupleuri, vinegar baked rhizoma cyperi, radix curcumae, tangerine seeds, semen litchi, seaweeds, prunella, rhizoma ligustici wallichii, prepared rhizome of rehmannia, angelica, red paeonia, leech, rhizoma sparganii, zedoary, cassia twig, radix astragali, tuckahoe, radix codonopsitis, and honey-fried licorice root. The intestinal obstruction removal pill has the advantages of the effects of promoting blood circulation by removing blood stasis, soothing the liver and promoting the circulation of qi, reducing phlegm and resolving masses, and supplementing qi and nourishing yin, and can effectively treat hyperplasia of mammary glands, oophoritic cyst and hysteromyoma.

The invention relates to an application of the fusion proteins FP1-FP8 of VEGF receptors on the treatment of the diseases relating to angiogenesis. The diseases relating to the angiogenesis includes autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, vasculitis, systemic sclerosis and other diseases caused by the angiogenesis such as bronchial asthma, obesity, nasal polyps, rhinitis, liver cirrhosis, endometriosis, uterine bleeding, warts, scars and ovarian cysts, etc.

The invention relates to a traditional Chinese medicine compound composition which can cure hysteromyoma and pelvic inflammatory mass of gynecology and is characterized in that: raw materials of the effective ingredients in the medicine and the portions by weight of the raw materials are as follows: 50 to 300 portions of radices salviae miltiorrhizae, 30 to 150 portions of radices pseudoginseng, 50 to 250 portions of angelica, 40 to 250 portions of Ramulus Cinnamomi, 50 to 300 portions of Tuckahoe, 50 to 250 portions of tree peony bark, 50 to 250 portions of radices paeoniae rubra, 50 to 250 portions of walnut meat, 50 to 250 portions of Astragalus hoangtchy, 50 to 250 portions of rhizoma sparganii, 50 to 250 portions of radices curcumae zedoariae, 20 to 100 portions of carapax amydae, 40 to 250 portions of Barbat Skullcap and 10 to 100 portions of cumin. The Chinese medicine composition of the invention is a corresponding pharmaceutical dosage form prepared by corresponding techniques of soaking, decocting for extraction, filtering, concentrating and so on. The traditional Chinese medicine composition of the invention can effectively activate blood circulation to dissipate blood stasis, soften hard mass and astringe yin and eliminate mass and stagnation and can be used for curing mass that women always have, blood stasis and amenia, dysmenorrheal, chronic pelvic inflammatory disease, cervicitis, hysteromyoma, ovarian cyst, pelvic inflammatory mass and so on.

The invention discloses a traditional Chinese medicine for promoting blood circulation and removing blood stasis, comprising the following raw material components by weight percent: 25-35 percent of radix astragali, 25-35 percent of angelica, 25-35 percent of tree peony bark, 25-35 percent of cassia twig, 25-35 percent of radix paeoniae rubra, 25-35 percent of poria alba, 25-35 percent of trigone,25-35 percent of rhizoma zedoariae, 25-35 percent of fresh peach kernel, 25-35 percent of safflower, 45-55 percent of fresh leech and 45-55 percent of fresh oyster. The traditional Chinese medicine has the effects of promoting blood circulation, removing blood stasis, promoting the circulation of qi and eliminating stagnation and is mainly used for treating hysteromyoma and ovarian cyst.

The invention belongs to a human Chinese medicinal preparation for treating uterus myoma. The preparation is prepared from the following Chinese medicinal raw materials in parts by weight: 9 to 15 parts of common burreed rhizome, 9 to 15 parts of zedoary, 8 to 14 parts of peach kernel, 8 to 14 parts of cassia twig, 16 to 24 parts of tuckahoe, 9 to 15 parts of root bark of peony, 10 to 18 parts of red peony root, and 8 to 14 parts of Szechuan lovage rhizome. The main Chinese medicinal preparation for activating blood, promoting qi circulation, softening hardness to dissipate stagnation and treating the uterus myoma shows that the uterus myoma is controlled in different degrees; the tumor body is reduced; the symptoms such as irregular menstruation, waist and abdomen pain, intimitis, ovarian cysts and the like are obviously improved; and the total effective rate is 95.3 percent.

A genetic means of determining whether a female subject produces "pregnancy competent" oocytes is provided. The means comprises detecting the level of expression of one or more genes that are expressed at characteristic levels (upregulated or downregulated) in cumulus cells derived from pregnancy competent oocytes. This characteristic gene expression level, or pattern referred to herein as the "pregnancy signature", also can be used to identify subjects with underlying conditions that impair or prevent the development of a viable pregnancy, e.g., pre-menopausal condition, other hormonal dysfunction, ovarian dysfunction, ovarian cyst, cancer or other cell proliferation disorder, autoimmune disease and the like. Microarrays containing "pregnancy signature" genes or corresponding polypeptides provide another preferred aspect of the invention. Still further, the subject invention can be used to derive animal models, e.g., non-human primate animal models, for the evaluation of the efficacy of putative female fertility treatments. Additionally, an improved RNA amplification protocol is provided herein referred to as the CRL amplification protocol which is suitable for reproducibly amplifying all the RNAs expressed by a cell sample, even when only a few cells are available.

The invention relates to a medicament preparation for treating gynecological disease and a preparation method and application thereof, wherein the medicament preparation for treating the gynecological disease is prepared into pills, capsules and the like through processing seven traditional Chinese medicines including cassia twig, tuckahoe, tree peony bark, red paeonia, peach kernel, angelica and spatholobus stem. The medicament preparation is a pure traditional Chinese medicine preparation, has the functions of promoting blood circulation, removing blood stasis and eliminating abdominal mass, is used for treating originally suffered abdominal mass or amenorrhea due to blood stasis of women, menstrual bellyache and postpartum lochiorrhagia, has good effect on treating the symptoms of hysteromyoma (particularly small intramural hysteromyoma), chronic pelvic inflammatory enclosed mass, endometrial irregular shedding functional bleeding, ovarian cyst, dysmenorrheal, endometrial abnormal taste and the like, avoids the side effect of long-term taken antibiotics, can not cause dual infection, has good security and no remarkable toxic or side effect, can be taken for a long time and makes up the defects of chronic aseprtic inflammation, adhesive enclosed mass antibiotics inefficacy and the like.

The invention discloses a Chinese medicine preparation for treating hysteromyoma and ovarian cyst and a preparation method. The Chinese medicine preparation is composed of the following raw material medicines: Chinese angelica, ligusticum wallichii, red flower, rhizoma sparganii, curcuma zedoary, cortex moutan, radix paeoniae alba, red paeonia, leonurus, costus root, sichuan magnolia bark, rhizoma cyperi, poria, rhizoma alismatis, fructus corni, Chinese yam, astragalus membranaceus and rehmannia glutinosa. The Chinese medicine preparation can be prepared into decoction and also can be prepared in to pills, and auxiliary materials for preparing the pills are honey and brown sugar. Raw material medicines of the Chinese medicine preparation interact with each other and coordinate together to play a role to the largest extent, the Chinese medicine preparation has remarkable effects in treating the hysteromyoma and the ovarian cyst, and effective rate can reach 98.4%. The Chinese medicine preparation is quick in effect taking, low in cost and small in toxic and side effects.

The invention relates to a method for increasing sow ovulation rate and injection thereof, belonging to the technical field of agricultural biological products. The method of simultaneously injecting PG (cloprostenol sodium) and PMSG (antostab) or a mixture of PG and PMSG before oestrum, and injecting HCG (chorionic corticotrophin) or LHRH-A3 (luteinizing hormone releasing hormone A3) during oestrum is adopted to promote the ovulation rate of young sows or multiparity sows to be 2-3 times of normal ovulation amount, thus improving reproductive performance of sows and obviously increasing the number of young pigs borne by the sows. The method has stable technology and obvious effect, and can not induce ovarian cyst; by using the method, the same superovulation effect can be achieved on standby sows ay any time before sexual maturity.

A leech capsule for treating blood stasis, hyspteromyoma, ovarian cyst, pelvic inflammation, etc is prepared from 9 Chinese-medicinal materials including leech, ground beetle, peach kernel, rhubarb, etc.

The invention discloses a pharmaceutical composition for treating ovarian cysts and a preparation method thereof, so as to solve the problem of ovarian cysts treatment. The composition of the invention is characterized by being prepared by the following raw herbs with certain proportion: white peony, astronomy grass, angelica, catclaw buttercup root, citrus aurantium, coix seed, dried tangerine peel, alisma, tree peony bark, poria, common pleione pseudobulb, cyperus rotundus, patrinia grass, spina gleditsiae, loofah, angelica dahurica, phellodendron bark, pangolin scales, and peach gum. The preparation method comprises: (1) volatile oil is extracted from the dried tangerine peel, the astronomy grass, the cyperus rotundus, the patrinia grass and the citrus aurantium crude powder for use; (2) the peach gum is crushed into fine powder for use; (3) the white peony, the angelica, the catclaw buttercup root, the coix seed, the tree peony bark, the alisma, the poria, the common pleione pseudobulb, the spina gleditsiae, the loofah, the angelica dahurica, the phellodendron bark, and the pangolin scales undergo water extracting-alcohol precipitating and an initial composition is obtained after drying; and (4) the volatile oil is injected into the initial composition; the peach gum fine powder is added; after mixing uniformly, the mixture passes through a 60 mesh sieve; and a capsule filled with the mixture is made. Clinical experiments prove that the composition of the invention has good curative effect and high safety for treating the ovarian cysts, and the composition is worth clinical application and promotion.

The invention discloses an oviduct dredging medicament for removing blood stasis and warming meridians, which is prepared by decocting and extracting peach kernel, safflower, cinnamon, citron, finger citron, tangerine peel, lesser galangal, licorice, angelica root, tuckahoe and houttuynia cordata as raw materials according to a certain proportion by weight. The medicament can be prepared into anycommon dosage form for oral administration, has the functions of promoting blood circulation for removing blood stasis, warming meridians for relieving pain, dredging obstruction, softening hardness and eliminating stagnation, and the like, has fine curative effects on oviduct obstruction, hydrosalpinx, unsmooth oviduct, dysmenorrhea due to blood stasis, ovarian cyst, and the like, and has the advantages of rapid effect, and no toxic or side effect.

The invention discloses a Chinese medicinal composition for treating ovarian cyst, which comprises Semen Vaccariae, Prunellae Spica, Concha Ostreae, Perillae Herba, Gekko Swinhonis, Radix Astragali, Radix Codonopsis, Ramulus Cinnamomi, Poria, Rhizoma Sparganii, Rhizoma Curcumae, Carapax Trionycis, Salviae Miltiorrhizae Radix and Hirudo. The Chinese medicinal composition has effects of promoting blood circulation to remove stasis, clearing away toxic substances, resolving tumor, and enhancing immunity; and has no side effects. After continuous administration for 30 days, the composition can eliminate ovarian cyst and recover body function.

The invention discloses a laparoscopic ovarian cyst stripping assist device. The laparoscopic ovarian cyst stripping assist device comprises a laparoscopic ovarian cyst stripping collection bag and ashrinkage assembly, wherein the shrinkage assembly is controlled by a tension microsensor and a tension controller, the laparoscopic ovarian cyst stripping collection bag comprises a bag body with three one-way hole structures and one shrinkable opening, and the laparoscopic ovarian cyst stripping collection bag is connected with the tension microsensor and a line winding wheel through compressionbelts in sequence. On the one hand, through the mutual movement of the laparoscopic ovarian cyst stripping collection bag and the shrinkage assembly, an operation space higher in airtightness is formed, and overflow, caused when a cyst wall is broken, of cyst fluid is avoided in the ovarian cyst stripping process; on the other hand, through the simple and convenient design, preoperative preparation work is simplified, the operation time is shortened, and the pain of a patient is reduced.

The invention discloses an external medicament for treating the hyperplasia of mammary glands and ovarian cyst. The external medicament comprises the following raw materials in equal parts by weight: coptis roots, amur corktree bark, frankincense, myrrh, radix pseudo-ginseng, gardenia, radix scutellariae, parasitic walnuts, safflowers, peach seeds and catecholamine. The medicament is prepared by grinding the 12 medicaments into fine medicinal powder and adding 2 to 3 percent of borneol and 2 to 3 percent of dragon blood based on the weight of the medicinal powder. The medicament has the effects of clearing heat, promoting diuresis, promoting blood circulation, removing blood stasis, dispersing swelling and dissipating binds, and has good curative effects on diseases such as the hyperplasia of mammary glands and the ovarian cyst.

The invention belongs to the technical field of ganoderma lucidum culture, and particularly discloses a method for culturing ganoderma lucidum in a high-altitude area and a method for preparing health-care products of ganoderma lucidum. Traditional Chinese medicine components comprise cordyceps sinensis, shiitake mushrooms, fructus schizandrae, rhodiola rosea, radix aconite lateralis, ganoderma lucidum, rhizoma dioscoreae, radix ginseng, cornu cervi, hippocampus japonicus and musk; a culture solution for culturing ganoderma lucidum is prepared through treatment; ganoderma lucidum is cultured in the high-altitude area by utilizing the culture solution, minerals, trace elements and other nutrients in the culture solution can be effectively absorbed by thalli of ganoderma lucidum, the nutrients of ganoderma lucidum can be added, the content of the nutrients of ganoderma lucidum can be increased, the growth state of ganoderma lucidum can also be improved, and the yield is increased; in addition, the prepared health-care products of ganoderma lucidum have the effects of treating constipation, chronic gastritis, gastroenteritis, diarrhea, ovarian cyst and the like.

The invention discloses a chemiluminescence quantitative detection kit for luteinizing hormone. The kit comprises a luteinizing hormone detection reaction plate, an enzyme conjugate, a luminescent substrate, a calibrator, a quality control material and washing concentrate, wherein the reaction plate is coated with a luteinizing hormone antibody. The kit can specifically and quantitatively detect the content of the luteinizing hormone in patient serum, and is used for the auxiliary diagnosis of diseases such as ovarian cyst, primary ovarian failure, dysfunction of hypophysis or hypothalamus, congenital testicular dysgenesis and the like. Compared with the conventional enzyme linked immunosorbent assay (ELISA) technology, the chemiluminescence immunoassay keeps high specificity of the ELISA technology, stability and reliability of a detection result, and convenience of operation, and can improve detection sensitivity simultaneously.

The invention relates to a traditional Chinese medicine for treating ovarian cyst which is characterized by consisting of raw material medicines according to the following weight ratios: 10-15g of radix bupleuri, 10-15g of angelica, 10-15g of radix paeoniae alba, 10-15g of bighead atractylodes rhizome, 15-20g of poria cocos, 10-15g of ligusticum wallichii, 10-12g of rhizoma cyperi, 15-20g of rhizoma sparganii, 15-20g of curcuma zedoary, 10-15g of Chinese honeylocust spine, 10-15g of safflower and 6-10g of liquorice. The traditional Chinese medicine has the total effective rate of 96%, curative rate of 80%, improvement rate of 16%, and ineffective rate of 4%.

The invention discloses an application of a traditional Chinese medicine composition. The active ingredients of the traditional Chinese medicine composition are made of raw materials in parts by weight: 12.57-18.85 parts of salvia miltiorrhiza, 4.18-6.28 parts of Sanqi, 6.67-9.03 parts of trigonum, and 4.45 parts of curcuma ~6.01 parts, peach kernel 5.34~7.22 parts, angelica 4.45~6.01 parts, turtle shell 6.07~9.03 parts, seaweed 11.13~15.05 parts, Eucommia 4.71~5.75 parts, fried Atractylodes macrocephala 7.06~8.64 parts, barbata 14.14~17.28 parts, 4.24-5.18 parts of cassia twigs, the traditional Chinese medicine composition can be used to prepare medicines for treating endometriosis, mammary gland hyperplasia and ovarian cysts. The medicine prepared by the traditional Chinese medicine composition of the present invention can be used alone in the treatment of endometriosis, mammary gland hyperplasia, and ovarian cyst, and is also suitable for EMT and ovarian cyst before and after surgery. relapse. Its notable feature is that it overcomes the hormone-like side effects of western medicine and the surgical discomfort caused by multiple lesions.

The invention provides a Miao national herb combination for treating gynecological inflammation and tumor and process for preparation, which is mainly prepared by raw materials of bittersweet herb, oldenlandia diffusa, and melastoma dodecandrum lour, or is used by the compatibility of part or all of clusiaceae, herb emilia, herb centellae, goldenrod, king melon seed, bidens. Compared with the prior art, the invention has the effects of clearing away heat and toxic materials, dissipating blood stasis and resolving mass, eliminating carbuncle and relieving pain, has favorable efficacy for gynecological inflammation caused by damp-heat and damp-toxin and phlegm-dampness stasis accumulation, hysteromyoma, cervical cancer, ovarian cyst, and pelvic inflammation mass, and has no toxic and side effects and drug-resistance. The invention is new Chinese medicine, which has the advantages of safety, efficiency, and controllable quality, worthwhile clinic application, favorable social and economic values.

The invention relates to a medicine, in particular to a medicine for treating female genitourinary system inflammation. The medicine is prepared by the following raw medicine materials in parts by weight: 25-35 parts of felwort, 8-12 parts of rhizoma alismatis, 8-12 parts of cortex dictamni, 8-12 parts of coptis, 25-32 parts of lightyellow sophora root, 7-13 parts of akebiaquinata, 8-12 parts of Cyrtomium fortunei, 7-14 parts of fineleaf schizonepeta herb, 12-20 parts of Chinese thorowax root, 12-18 parts of plantain seed, 12-18 parts of golden cypress, 7-12 parts of stiff silkworm, 9-12 parts of pangolin scale, 12-18 parts of Salvia miltiorrhiza Bunge, 8-15 parts of licorice root, 12-20 parts of Chinese angelica, 12-20 parts of divaricate saposhnikovia root and 8-15 parts of fructus cnidii. The invention has the advantages that the effects of the medicine on female genitourinary system inflammation, including acute and chronic vaginitis, pruritus vulvae, leucorrhea increase, peculiar smell, cervicitis, cervical erosion, pelvic inflammation, ovarian cyst and the like according to a great amount of clinical experiments are obvious, and certain efficacies on mammary gland proliferation, hysteroptosis, uterine myoma, endometriosis and the rehabilitation therapy after delivery operation are also obtained.

A genetic means of determining whether a female subject produces “pregnancy competent” oocytes is provided. The means comprises detecting the level of expression of one or more genes that are expressed at characteristic levels (upregulated or downregulated) in cumulus cells derived from pregnancy competent oocytes. This characteristic gene expression level, or pattern referred to herein as the “pregnancy signature”, also can be used to identify subjects with underlying conditions that impair or prevent the development of a viable pregnancy, e.g., pre-menopausal condition, other hormonal dysfunction, ovarian dysfunction, ovarian cyst, cancer or other cell proliferation disorder, autoimmune disease and the like. Microarrays containing “pregnancy signature” genes or corresponding polypeptides provide another preferred aspect of the invention. Still further, the subject invention can be used to derive animal models, e.g., non-human primate animal models, for the evaluation of the efficacy of putative female fertility treatments.

The invention discloses an externally-applied traditional Chinese medicine composition for treating gynecological diseases. The externally-applied traditional Chinese medicine composition is prepared from the following raw materials in part by weight: 6-10 parts of rhizoma coptidis, 5-7 parts of rhubarb, 6-10 parts of cortex phellodendri, 10-15 parts of bulbus fritillariae cirrhosae, 0.5-1 part of musk, 5-10 parts of elephant skin, 3-5 parts of calcined pearl, 15-20 parts of spina gleditsiae, 10-15 parts of radix trichosanthis, 10-15 parts of sanguis draconis, 10-15 parts of frankincense, 10-15 parts of myrrh, 10-15 parts of shrubalthea bark and 3-5 parts of borneol. The traditional Chinese medicine composition has functions of clearing heat and removing toxin, diminishing inflammation and drying dampness, activating blood and resolving stasis, dissipating swell and mass, fixing pain and promoting granulation, relieving itching and sterilizing, eliminating putridity to promote regeneration and healing ulcer; the traditional Chinese medicine composition is effective in comprehensively treating gynecological diseases, and has an obvious curative effect; and moreover, the traditional Chinese medicine composition has an obvious therapeutic action on diseases such as uterine fibroid, ovarian cyst, cervical cyst, pelvic effusion, hydrosalpinx, cervical erosion, stink type leukorrhea with reddish discharge and the like, and can be used as externally-applied traditional Chinese medicine powder having gynecological prevention and healthcare functions.

The invention discloses a medicament for treating ovarian infertility, which is constituted by compound Chinese medicines. The medicine provided by the invention comprises the following medicinal components in weight proportion: epimedium herb 40-120, actinolite 30-100, root of red-rooted salvia 25-100, safflowers 25-100, motherwort herb 30-120, Chinese angelica 30-100, astragalus root 25-120, south dodder seed 30-120, common burreed rhizome 10-60, zedoary root 10-60 and twotooth achyranthes root 20-90. Experiments show that the medicament can be used for treating various diseases, such as hypo-ovarianism (inactive ovary), persistent corpus luteum, ovarian cyst, alternate follicle development, delayed ovulation and the like, and can substitute traditionally applied hormone and antibiotics medicines completely or to certain extent, therefore, the medicament is an important remedial measure indispensable to prevention and treatment of milk cow infertility.