30 results about "Cysts fluid" patented technology

The invention discloses a microwave ablation needle antenna with an infusion structure for curing cyst and belongs to microwave ablation antennas. The microwave ablation needle antenna comprises an antenna rod body and a handle. The antenna rod body is connected with the handle. A radiator is arranged at the front head of an inner portion of the antenna rod body. A needle radiator sleeve is arranged on the radiator and further arranged at the end of the antenna rod body. The radiator is connected with a radio frequency coaxial connector which is arranged at the tail end of the antenna rod body through a coaxial cable. A water inlet channel and a water outlet channel are further arranged in the antenna rod body and communicated with each other. An independent injection channel is arranged in the antenna rod body. At least one through hole is formed in the front end of the antenna rod body. The injection channel is communicated with the outside through the through hole. Through the injection channel in the antenna rod body, artificial irrigation fluid is injected to do auxiliary cleaning during the microwave ablation of the cyst by the needle antenna, and cyst fluid generated from the microwave ablation is sucked. Thus technical effect identical with that of sclerosis therapy is achieved during the microwave ablation.

A diagnostic test and method is provided comprising mixing blood or another biological fluid sample with a test compound and spotting the blood on filter paper for subsequent analysis of the effect of the test compound on the blood. The biological fluid can be a cerebrospinal fluid, a peritoneal fluid, a cyst fluid, an amniotic fluid, a lavage fluid, a saliva, a cell extract or a tissue extract. The compound is chosen among an amino acid, a peptide, a protein, a carbohydrate, an oligosaccharide, a polysaccharide, a glycoprotein, a lipid, a lipoprotein, a glycosaminoglycan, a hormone, a steroid, a vitamin, a low molecular weight synthetic or natural compound which influences the blood to cause an alteration of its composition, e.g., a toxin, allergen, autoantigen, bacterial protein or polysaccharide, viral protein, fungal protein or polysaccharide, parasitic protein or polysaccharide, bacterial lipopolysaccharide or any other compound relevant to diseases.

The invention relates to a thyroid puncture device, and belongs to the technical field of medical tool structures. The thyroid puncture device comprises an injector; a needle body in which a needle core is mounted is connected to the front of the injector; an one-way valve is arranged at an inlet of the injector; a pushing handle is arranged in the injector; a negative pressure pipe equipped with a piston is fixedly mounted at one side of the injector, and while a fluid storing bottle is mounted at the other side of the injector. According to the thyroid puncture device, the negative pressure pipe is arranged and can generate sufficient negative pressure to absorb cyst fluid, and the absorbed cyst fluid is enough for diagnosis; the liquid storing bottle is arranged, so that cyst fluid can be extracted at a plurality of times; the cyst fluid can be smoothly extracted in case of thick fluid or solid nodule mass; in addition, scales in the fluid storing bottle are able to accurately control the volume of the fluid extracted, which greatly facilitates the diagnosis and treatment of diseases.

The invention discloses a laparoscopic ovarian cyst stripping assist device. The laparoscopic ovarian cyst stripping assist device comprises a laparoscopic ovarian cyst stripping collection bag and ashrinkage assembly, wherein the shrinkage assembly is controlled by a tension microsensor and a tension controller, the laparoscopic ovarian cyst stripping collection bag comprises a bag body with three one-way hole structures and one shrinkable opening, and the laparoscopic ovarian cyst stripping collection bag is connected with the tension microsensor and a line winding wheel through compressionbelts in sequence. On the one hand, through the mutual movement of the laparoscopic ovarian cyst stripping collection bag and the shrinkage assembly, an operation space higher in airtightness is formed, and overflow, caused when a cyst wall is broken, of cyst fluid is avoided in the ovarian cyst stripping process; on the other hand, through the simple and convenient design, preoperative preparation work is simplified, the operation time is shortened, and the pain of a patient is reduced.

A diagnostic test for ovarian cysts is based on the detection of mutations characteristic of the most common neoplasms giving rise to these lesions. With this test, tumor-specific mutations were detected in the cyst fluids of 19 of 24 (79%) borderline tumors and 28 of 31 (90%) malignant ovarian cancers. In contrast, we detected no mutations in the cyst fluids from 10 non-neoplastic cysts and 12 benign tumors. When categorized by the need for exploratory surgery (i.e., presence of a borderline tumor or malignant cancer), the sensitivity of this test was 85% and the specificity was 100%. These tests could inform the diagnosis of ovarian cysts and improve the clinical management of the large number of women with these lesions.

The invention relates to the technical field of human and animal alveolar echinococcosis (AE) antibody detections, specifically to cystic echinococcosis (CE) cyst fluid degreasing antigen for detecting AE antibody, and a preparation method thereof. According to the present invention, the CE cyst fluid degreasing antigen is used for detecting AE antibody by using an enzyme-linked immunosorbent test double antigen sandwich method so as to effectively increase quality of the detection reagent, and provide characteristics of strong specificity, high sensitivity, stable performance and wide uses; the CE cyst fluid degreasing antigen can be used for detecting human and animal AE antibodies so as to conveniently compare antibody contents of different animal varieties; and according to the immunological reaction principle, the CE cyst fluid degreasing antigen further can be used for preparing colloidal gold immunochromatography reagents and other rapid detection reagents for detecting AE antibodies so as to create favorable conditions for echinococcosis identification diagnosis, prevalence surveys and epidemic situation surveillance works.

The invention relates to a medical device which is used for aspirating local fluids from a breast and particularly relates to a breast cyst fluid aspirate device with an extrusion device. The breast cyst fluid aspirate device comprises a vacuum pump, a cup and a liquid aspirating tube, wherein the vacuum pump produces vacuum suction forces, the cup covers a breast, the liquid aspirating tube is communicated with the vacuum pump and the cup, a nipple shield is arranged in the cup, the nipple shield comprises a first circular portion, a second circular portion and a cylinder portion which are sequentially fixed and communicated with one another, the first circular portion is in seal fit with the breast, the second circular portion accommodates the front end of the breast, the cylinder portion accommodates a nipple and is communicated with a telescopic flexible tube, the telescopic flexible tube is communicated with the liquid aspirating tube which is connected with the cup, the cup is further connected with one end of a pressuring tube, and the other end of the pressuring tube is connected with a gas supply device. The breast cyst fluid aspirate device with the extrusion device is simple in structure, a pin is not required for puncturing, and a breast pump vacuum liquid aspirating device is used for aspirating cyst fluids to achieve effects of non-invasive type breast cyst fluid aspirating.

The invention relates to a puncture sheath used for cyst excision and a cyst excision device provided with the puncture sheath. The cyst excision device comprises the puncture sheath, the puncture sheath comprises a puncture sheath body with the axis extending in the front-back direction, the front end of the puncture sheath body is provided with an insertion segment inserted into a cyst, the insertion segment is provided with a front sheath umbrella capable of being opened and retracted in the radial direction, a rear sheath umbrella capable of being opened and retracted in the radial direction is arranged on the rear side of the insertion segment and on the puncture sheath body, and the front sheath umbrella and the rear sheath umbrella are matched to clamp the wall of the cyst. The cyst excision device further provides an excision structure, and the puncture sheath further comprises a drive structure used for driving the front sheath umbrella and the rear sheath umbrella to be opened and retracted in the radial direction. When the cyst excision device is used, the front sheath umbrella is inserted into the cyst, and the wall of the cyst is excised through the excision structure. Compared with the mode that in the prior art, cyst fluid is discharged first and then anhydrous alcohol is injected, the cyst is not likely to relapse because the top wall of the cyst is excised. Compared with an open operation in the prior art, an incision is small, and trauma to the body of a patient is small.

The invention relates to suction of tumor cyst fluids, in particular to an anti-leakage puncture suction sleeve and a use method thereof. The puncture suction sleeve comprises a hollow pipe, the frontend of the hollow pipe can penetrate into a tumor along with a puncture suction device; the puncture suction device is sleeved with an inner cavity of the hollow pipe, the front end of the hollow pipe is provided with a front bag and a rear bag, and after the front bag and the rear bag are inflated, a puncture opening, penetrated by a puncture needle of the puncture suction device, of a tumor isclamped and sealed. According to the puncture suction sleeve, the front and rear bags arranged at the front end of the hollow pipe continuously expand after being inflated and abut against each other,so that the tumor cyst wall around the puncture opening is clamped, the purpose of sealing the puncture opening is achieved, and leakage prevention of tumor cyst fluids is realized. Moreover, the twoinflatable bags can also stably position a puncture suction sleeve body onto the tumor to facilitate puncture operation.

The invention discloses a novel therapeutic device for popliteal cysts. The novel therapeutic device comprises a puncture core, an output tube side hole, an input tube side hole, an input tube, an output tube, an input tube connector, a liquid bag, a positive-pressure hemisphere, a positive-pressure hemisphere valve, a negative-pressure hemisphere valve, a separation plate, a negative-pressure hemisphere, a check valve, an output tube connector and a liquid bag valve. The input tube and the output tube are flexible rubber hoses. The novel therapeutic device for the popliteal cysts has the advantages that when the device is used for treating the popliteal cysts, the output tube is punctured into the popliteal cysts under the guide of B-mode ultrasound, the input tube and the output tube areconnected to drain cyst liquid in the popliteal cysts to reduce the popliteal cysts, high-concentration medical alcohol in the liquid bag is injected into the popliteal cysts to burn and damage the walls of the cysts, and cyst tissues are adhered, shrink and finally disappear. By the novel therapeutic device, incision scar proliferation and discomfort both brought by popliteal cystectomies can bereduced. Through clinical practice, the novel therapeutic device has the advantages of small wound, small pain, quick recovery and repeatability.

The invention provides a cyst fluid suction device which comprises a suction pipe. The tail end of the suction pipe is connected with a sealing cover in a penetrating mode and is communicated with a measuring glass. The sealing cover and the measuring glass are connected in a sealed mode to form a negative-pressure bin. The sealing cover is provided with a secondary straw communicated with the measuring glass. The secondary straw is communicated with a negative-pressure gas storage tank communicated with a negative-pressure chamber. The negative-pressure chamber is communicated with a negative-pressure pump arranged in a liquid suction machine shell. Cyst fluid is automatically sucked by setting suction data, and an operation can be assisted to be completed standardly and efficiently. Besides, proper suction modes can be customized according to different cases, adaptability is high, operation burdens of doctors are relieved, and work efficiency is improved.

A blocking ELISA method for detecting a cysticercosis pisiformis cyst fluid antibody of a rabbit is used for early detection and clinical diagnosis of cysticercosis pisiformis of the rabbit, solves the problem that at present, the cysticercosis pisiformis of the rabbit cannot be diagnosed by using a serological method, and is an effective detection method for specificity diagnosis and comprehensive prevention and control of the cysticercosis pisiformis of the rabbit. The blocking ELISA method includes the following three steps of purification of a cysticercosis pisiformis cyst fluid, antigenicity detection of purified protein and establishment of the blocking ELISA detection method. The rapid, sensitive and specific blocking ELISA method is used for detecting the specific cyst fluid antibody in the serum of the rabbit suffering from the cysticercosis pisiformis, is good in result stability, can be commercialized and automatic and can be also used for determination with naked eyes. Therefore, the blocking ELISA method is expected to become an important tool clinically for rapid diagnosis and immune detection of the cysticercosis pisiformis of the rabbit, will certainly play an important role in diagnosis and prevention and control of the cysticercosis pisiformis of the rabbit and has good application prospect.

A diagnostic test for ovarian cysts is based on the detection of mutations characteristic of the most common neoplasms giving rise to these lesions. With this test, tumor-specific mutations were detected in the cyst fluids of 19 of 24 (79%) borderline tumors and 28 of 31 (90%) malignant ovarian cancers. In contrast, we detected no mutations in the cyst fluids from 10 non-neoplastic cysts and 12 benign tumors. When categorized by the need for exploratory surgery (i.e., presence of a borderline tumor or malignant cancer), the sensitivity of this test was 85% and the specificity was 100%. These tests could inform the diagnosis of ovarian cysts and improve the clinical management of the large number of women with these lesions.

A diagnostic test and method is provided comprising mixing blood or another biological fluid sample with a test compound and spotting the blood on filter paper for subsequent analysis of the effect of the test compound on the blood. The biological fluid can be a cerebrospinal fluid, a peritoneal fluid, a cyst fluid, an amniotic fluid, a lavage fluid, a saliva, a cell extract or a tissue extract. The compound is chosen among an amino acid, a peptide, a protein, a carbohydrate, an oligosaccharide, a polysaccharide, a glycoprotein, a lipid, a lipoprotein, a glycosaminoglycan, a hormone, a steroid, a vitamin, a low molecular weight synthetic or natural compound which influences the blood to cause an alteration of its composition, e.g., a toxin, allergen, autoantigen, bacterial protein or polysaccharide, viral protein, fungal protein or polysaccharide, parasitic protein or polysaccharide, bacterial lipopolysaccharide or any other compound relevant to diseases.

The present invention relates to a laparoscopic device used in laparoscopic cyst hydatid operations, which has a shaft that enables simultaneous performance of the breaking of the cyst content in the area by the blade in the conical slot at the end of the shaft, aspiration of the cyst fluid and the broken female vesicles and if required, washing processes and an electrically connected hand unit. The mentioned laparoscopic device contains a motor inside the hand unit, motor drive unit, cycle unit, cycle control unit and trigger and the shaft part contains aspiration channel, washing channel, the shaft enabling the blade movement and blade unit in

The invention relates to a medical instrument, and particularly discloses a cyst fluid puncture aspirator for a patient. The puncture device comprises a puncture tube, the diameter of the head end of the puncture tube is changed into a rectangular pyramid table tube, a liquid suction hole is formed in the portion, behind the rectangular pyramid table tube, of the puncture tube, a puncture suction head is installed at the end of the rectangular pyramid table tube, the puncture suction head is hinged to the upper end of an inclined face through a hinge shaft, and the puncture suction head is a rectangular pyramid hollow body. The lower end part of the hollow body is positioned in the rectangular pyramid table pipe; when the puncture suction head rotates under the action of external force, the whole puncture suction head can rotate into the rectangular pyramid frustum tube. The puncture suction head is provided with the tip and can rotate, and after penetrating through the cyst, the puncture suction head rotates into the rectangular pyramid table pipe under the action of airflow formed by liquid in the cyst and under the pulling of the pull rope, so that the tip cannot puncture blood vessels and nerves in the cyst, secondary injury to a patient cannot be caused, and the puncture suction head is safe and efficient.

The invention relates to the technical field of puncture needles, in particular to a ganglion puncture needle. The ganglion puncture needle comprises a connecting pipe, a push rod and a spiral elasticstrip, wherein the head end of the connecting pipe is provided with an opening, the tail of the connecting pipe is provided with a needle body, the tail of the needle body is a sharp part, the portion, close to the sharp part, of the needle body is provided with penetration holes, the pipe wall of the connecting pipe is obliquely provided with a branch pipe communicated with the connecting pipe,the head end of the elastic strip is located in the branch pipe, the tail end of the elastic strip penetrates through the connecting pipe to reach the sharp part, the push rod is movably inserted in the branch pipe, and the tail end of the elastic strip is provided with an annular part formed by bending. The ganglion puncture needle has the advantages that the annular part rotates to constantly stir cyst fluid in the cyst, so that the cyst fluid moves to the sharp part, the cyst fluid is accordingly uniform and easy to absorb, it is ensured that the cyst fluid is sucked thoroughly, meanwhile,the rotary motion of the elastic strip is utilized to avoid the situation that substances in the cyst fluid block a needle cavity of the needle body, and the dredging effect on the needle cavity of the needle body is good.

A puncture device for thyroid cyst comprises an arc-shaped plate, under the arrangement, a puncture needle can move with a skin puncture point as a fulcrum, the arc-shaped angle of the arc-shaped plate ranges from 30 degrees to 90 degrees, the arc-shaped angle is the angle adjustable range of the puncture needle, and when facing the parenchyma part of the cyst, the puncture needle can be driven by the arc-shaped plate to move. The puncture angle can be adjusted in a small range to obtain acupuncture cells at different positions, an acupuncture module and a puncture angle limiting module are arranged on the arc-shaped plate, the acupuncture module is used for puncturing cysts, and the puncture angle limiting module is used for improving the stability during puncture. A colloidal cyst diluting module is further arranged on the needling module and used for rapidly diluting viscous cyst fluid, an adjusting module used for adjusting the position and the angle of the arc-shaped plate is further arranged on the device, and the needling module is used for achieving transdermal cyst puncture. The needling module comprises a mother cylinder, and the inner side of the mother cylinder is connected with a son cylinder in a sliding mode.

The invention relates to the technical field of human and animal alveolar echinococcosis (AE) antibody detections, specifically to cystic echinococcosis (CE) cyst fluid degreasing antigen for detecting AE antibody, and a preparation method thereof. According to the present invention, the CE cyst fluid degreasing antigen is used for detecting AE antibody by using an enzyme-linked immunosorbent test double antigen sandwich method so as to effectively increase quality of the detection reagent, and provide characteristics of strong specificity, high sensitivity, stable performance and wide uses; the CE cyst fluid degreasing antigen can be used for detecting human and animal AE antibodies so as to conveniently compare antibody contents of different animal varieties; and according to the immunological reaction principle, the CE cyst fluid degreasing antigen further can be used for preparing colloidal gold immunochromatography reagents and other rapid detection reagents for detecting AE antibodies so as to create favorable conditions for echinococcosis identification diagnosis, prevalence surveys and epidemic situation surveillance works.

The invention relates to a puncture sheath used for cyst excision and a cyst excision device provided with the puncture sheath. The cyst excision device comprises the puncture sheath, the puncture sheath comprises a puncture sheath body with the axis extending in the front-back direction, the front end of the puncture sheath body is provided with an insertion segment inserted into a cyst, the insertion segment is provided with a front sheath umbrella capable of being opened and retracted in the radial direction, a rear sheath umbrella capable of being opened and retracted in the radial direction is arranged on the rear side of the insertion segment and on the puncture sheath body, and the front sheath umbrella and the rear sheath umbrella are matched to clamp the wall of the cyst. The cyst excision device further provides an excision structure, and the puncture sheath further comprises a drive structure used for driving the front sheath umbrella and the rear sheath umbrella to be opened and retracted in the radial direction. When the cyst excision device is used, the front sheath umbrella is inserted into the cyst, and the wall of the cyst is excised through the excision structure. Compared with the mode that in the prior art, cyst fluid is discharged first and then anhydrous alcohol is injected, the cyst is not likely to relapse because the top wall of the cyst is excised. Compared with an open operation in the prior art, an incision is small, and trauma to the body of a patient is small.

The invention relates to a lock catch type loop ligature tightening ring. The lock catch type loop ligature tightening ring comprises a tightening belt and a lock catch; the tightening belt comprisesa binding section located in the middle and clamping sections located at the two ends of the binding section; the lock catch comprises a shell; a fastening hole penetrating through the shell is formedin the shell; the clamping sections of the tightening belt are oppositely bent; and the two clamping sections which are bent oppositely penetrate through the fastening hole from the inserting end ofthe fastening hole and slide in one direction with the fastening hole, and after the clamping sections at the two ends of the fastening belt penetrate through the fastening hole, the binding section forms a binding ring. The lock catch type loop ligature tightening ring has the advantages that the tightening ring is convenient to operate, and meanwhile, the neck of a cyst including a leakage opening is directly ligated and fastened through the irreversible lock catch, and it is guaranteed that cyst fluid does not permeate into the cyst any more.

The invention discloses a method for separation, purification and immunogenicity detection of cysticercosis pisiformis cyst fluid protein. The method comprises steps of pretreatment of ultrafiltration centrifugation tubes, treatment of cyst fluid protein, centrifugal treatment, collection of high molecular weight target protein and small molecular weight target protein, antigenic detection of purified cyst fluid protein with different molecular weights and the like. The method is simple to operate, the time course is short, the efficiency is high, action of ultrafiltration membranes is more sensitive and accurate, the concentration of the obtained purified protein is higher and purer, the protein recovery amount is large, and the purified protein with high antigenicity can be obtained. The method is a more ideal new method for separating and purifying the cyst fluid protein and detecting the immunogenicity of the purified protein.

The invention discloses a non-coding RNA (Ribonucleic Acid) expression profile analysis method for echinococcus granulosus protoscolex derived exosomes and cyst fluid derived exosomes. The method comprises the following steps: 1) separating echinococcus granulosus protoscolex from cyst fluid; (2) culturing the echinococcus granulosus protoscolex in vitro; (3) separating theechinococcus granulosus protoscolex derived exosomes and the cyst fluid derived exosomes , and obtaining the protoscopes derived exosomes PSC-ELVs and the cystic fluid derived exosomes HF-ELVs; 4) carrying out transmission electron microscope analysis; 5)carrying out nano particle size tracking analysis; (6)carrying out Western blotting; (7) constructing a miRNA library and sequencing; 8) constructing a whole transcriptome sequencing library and performing sequencing analysis; and (9) constructing a ceRNA regulation network. In addition, the invention also discloses non-coding RNA of the echinococcus granulosus protoscolex derived exosomes and cyst fluid derived exosomes obtained by screening with the method. According to the invention, the non-coding RNA expression profiles in the echinococcus granulosus protoscolex derived exosomes and the cyst fluid derived exosomes are obtained for the first time internationally.

The present invention provides an echinococcosis diagnosis immunochromatography test strip based on circulating antigen detection. the echinococcosis diagnosis immunochromatography test strip comprises a sample pad, a colloidal gold probe pad, a cellulose membrane and a water absorption pad, the cellulose membrane is provided with a detection line and a quality control line, the colloidal gold probe pad comprises a monoclonal antibody which is labeled by colloidal gold and is specifically combined with an echinococcosis cyst fluid antigen, and the monoclonal antibody on the colloidal gold probe is generated by a mouse hybridoma cell with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.22389; and one detection line comprises a monoclonal antibody specifically combined with an echinococcosis cyst fluid antigen, and the monoclonal antibody on the detection line is generated by mouse hybridoma cells with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.22388. The echinococcosis diagnosis immunochromatography test strip has the advantages of simplicity, sensitivity, specificity and rapidness, and is suitable for clinical and on-site use.

The present invention provides methods for determining malignancy in a cyst by measuring viscosity of cyst fluid while under stain. The invention further provides devices, and computer program products for determining same.

The invention discloses a laparoscopic ovarian cyst stripping assist device. The laparoscopic ovarian cyst stripping assist device comprises a laparoscopic ovarian cyst stripping collection bag and ashrinkage assembly, wherein the shrinkage assembly is controlled by a tension microsensor and a tension controller, the laparoscopic ovarian cyst stripping collection bag comprises a bag body with three one-way hole structures and one shrinkable opening, and the laparoscopic ovarian cyst stripping collection bag is connected with the tension microsensor and a line winding wheel through compressionbelts in sequence. On the one hand, through the mutual movement of the laparoscopic ovarian cyst stripping collection bag and the shrinkage assembly, an operation space higher in airtightness is formed, and overflow, caused when a cyst wall is broken, of cyst fluid is avoided in the ovarian cyst stripping process; on the other hand, through the simple and convenient design, preoperative preparation work is simplified, the operation time is shortened, and the pain of a patient is reduced.