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Application of lauromacrogol injection as drug for curing cesarean scar pregnancy

A technology of injection and lauromacrogol, which is applied in the application field of lauromacrogol injection as a drug for treating cesarean section scar pregnancy, can solve the problems of difficult promotion in grassroots hospitals, high technical difficulty, and few professionals, so as to reduce bleeding The effect of risk, simple technology, and low equipment requirements

Inactive Publication Date: 2016-03-23
张淑珍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

⑸ Uterine artery embolization to reduce the blood supply to the uterine scar, and then perform embryo ablation. This method has a positive effect in reducing bleeding during embryo ablation, but the technique is difficult, there are few professionals, the training period is long, and equipment requirements High, requires expensive digital imaging technology, the cost is about 10,000 yuan, and it is difficult to promote in primary hospitals; and because it is an intravascular operation, there is a risk of blood vessel rupture, ovarian artery, and pulmonary artery embolism. Once it occurs, the consequences will be serious.
Lauromacrogol injection is widely used in the treatment of esophageal varicose veins, but it has not been reported in the treatment of cesarean scar pregnancy

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Lauromacrogol belongs to polyoxyethylene lauryl ether compounds and is used internationally to treat varicose veins of the lower extremities and esophageal varicose veins. After lauromacrogol injection, it can damage the vascular endothelium, promote thrombus formation, block blood vessels, and block the source of blood supply; especially after injection around the gestational sac or around the gestational sac, a layer of dense fibrous tissue will gradually form around the gestational sac , causing vascular damage and permanent occlusion. At present, there is no international report on the application of lauromacrogol injection under the guidance of ultrasound as a drug for the treatment of cesarean section scar pregnancy. Because the technology is simple and easy to master, the only equipment required is an ultrasound machine. It has been clinically tested for 2 years, and the effect is positive. Promote the use of various grassroots units.

[0021] 1 object of treatm...

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PUM

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Abstract

The invention relates to the field of lauromacrogol injection drug application, and discloses application of lauromacrogol injection as a drug for curing cesarean scar pregnancy. The drug is applied according to the following steps: step (1), a focus scope, a muscular layer thickness and the blood supply situation of a focus location are determined by ultrasound contrast; step (2), the vagina is conventionally disinfected and a towel is spread at a lithotomy position of a patient; step (3), under ultrasonic guidance, the lauromacrogol injection is injected at a peripheral muscular layer of a gestational sac and around the gestational sac, until annular or flaky reinforcement of the gestational sac is seen under ultrasound and peripheral blood is sparse, wherein the specification of the lauromacrogol injection is that each 10ml of injection contains 100mg of lauromacrogol. According to the application of the lauromacrogol injection as the drug for curing cesarean scar pregnancy, the lauromacrogol injection is adhered to the inside of a vessel at the injection site, thus prompting a fibrosis strip to replace the pathological vessel, resulting in permanent occlusion of the vessel around the gestational sac, interdicting an open vessel at the pathological location, and greatly reducing bleeding risk in induced abortion operation.

Description

technical field [0001] The invention relates to the application field of lauromacrogol injection, in particular to the application of lauromacrogol injection as a drug for treating cesarean scar pregnancy. Background technique [0002] In cesarean section scar pregnancy, due to the weak or even missing myometrium at the uterine scar site, the lack of effective contractile force at the uterine incision site during artificial abortion will lead to continuous opening of local blood vessels, causing massive bleeding and even endangering the patient's life. [0003] At present, there are mainly the following methods for the treatment of uterine incision pregnancy: (1) Drugs (mifepristone orally or intramuscular injection of methotrexate) reduce the viability of the embryo, and the blood supply is reduced, and then the embryo removal operation is performed, and the treatment period of this method is long. , due to tissue necrosis and adhesion to the scar site, there is still a lot...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/765A61P15/00A61P9/14
CPCA61K9/0019A61K9/08A61K31/765
Inventor 张淑珍
Owner 张淑珍
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