8 results about "Hemorrhagic risk" patented technology

The application belongs to the technical field of biomedicine, and particularly relates to a construction system of a cerebral amyloid angiopathy recognition model, a storage medium and a kit. Based on plasma proteomic data of cerebral amyloid angiopathy patients and normal old controls, six key protein markers closely related to cerebral amyloid angiopathy are screened out. The application also provides a model for recognizing cerebral amyloid angiopathy based on a combination of six plasma protein biomarkers. The model shows excellent performance in multiple independent data sets, can accurately distinguish cerebral amyloid angiopathy patients from normal old controls, and further distinguish cerebral amyloid angiopathy patients with high-risk cerebral hemorrhage risk from those with low-risk cerebral hemorrhage risk. The application provides a new tool for early diagnosis and hemorrhage risk assessment of cerebral amyloid angiopathy.

This invention relates to a pharmaceutical composition and its application for treating acute ischemic stroke. The pharmaceutical composition for treating acute ischemic stroke comprises separately packaged tissue-type plasminogen activator citPA5 and a platelet aggregation inhibitor. Its beneficial effects include significantly improving cerebral blood flow recovery, shortening thrombolysis time, reducing infarct volume, and improving neurological function without increasing the risk of bleeding, demonstrating a good synergistic thrombolytic effect.

This invention provides an aneurysm embolization auxiliary device, belonging to the field of medical device technology. The device includes a delivery catheter, an operating handle, a balloon, and a filling unit. The delivery catheter delivers a treatment device to the aneurysm location. The operating handle is located at the proximal end of the delivery catheter. The balloon, after inflation, supports the blood vessel. The filling unit fills the aneurysm with an injectable gel for treating the aneurysm from the operating handle location along the delivery catheter. The injectable gel solidifies within the aneurysm. During operation, the delivery catheter delivers the balloon to the aneurysm location. After inflation, the balloon supports and positions the blood vessel. The filling unit fills the aneurysm with the injectable gel, which solidifies upon entering the aneurysm to treat it. This invention primarily addresses technical problems in existing interventional aneurysm treatment methods, such as easy displacement of coils and the increased risk of bleeding due to the need for long-term medication after stent implantation.

The application discloses a kind of multi-factor risk assessment methods for ovarian hyperstimulation, it is related to intelligent medical technical field, including, based on multi-source baseline data package, the trend of follicle volume change with time is calculated by ovarian response simulation, obtain follicle response curve, the probability of vascular injury is calculated by puncture path hemorrhage simulation, obtain bleeding probability, and the follicle response curve and bleeding probability are fused, form patient characteristic risk vector;According to the intervention suggestion in the structured strategy list is associated with ovarian hyperstimulation risk score and bleeding risk score to generate risk change description, and form risk assessment report according to risk change description;The application constructs the patient characteristic risk vector by fusing follicle dynamic response and puncture bleeding risk, effectively enhance the safety and individualization level of assisted reproductive treatment.

The embodiment of the specification provides a method, device, medium and program product for constructing a post-percutaneous renal biopsy hemorrhage risk prediction model, and relates to the field of intelligent medical treatment. The method comprises the following steps: obtaining preoperative target parameters of training set samples, obtaining postoperative imaging data of the training set samples subjected to percutaneous renal biopsy, and extracting an outcome index for evaluating the hemorrhage risk from the postoperative imaging data, wherein the outcome index comprises (hematoma long diameter+hematoma short diameter) / 2; taking the outcome index as a verification standard, evaluating the prediction ability of the preoperative target parameters on the postoperative hemorrhage risk, and obtaining an evaluation result; and constructing a hemorrhage risk prediction model based on the preoperative target parameters according to the evaluation result. The application adjusts the outcome index for judging whether to hemorrhage and the hemorrhage risk after operation, proposes a new hemorrhage risk definition, and is used for precise prediction, real-time prediction and individualized prediction on patients who are about to perform percutaneous renal biopsy.

This invention relates to the field of intelligent medical data analysis technology, specifically to a method and system for the intelligent prevention and control of venous thromboembolism in hospitalized patients. The method involves acquiring static medical record features and determining target test indicators; determining the target time window through a closed-loop adaptive mechanism driven by the fitting uncertainty of a Gaussian process regression model; constructing a weighted bipartite graph and removing confounding factors based on the topological overlap of pathological pathways to extract pure thrombosis baseline scores and pure bleeding baseline scores; extracting the first and second derivatives of time-series data and concatenating them with the pure baseline scores to construct a dynamic feature vector; generating a baseline-driven adaptive boundary in a two-dimensional phase plane; constructing a short-range predicted trajectory based on Taylor expansion and solving for the collision time; performing multi-objective game arbitration based on the time priority principle to generate prevention and control strategies; and achieving forward-looking joint decision-making in a dynamic conflicting scenario of thrombosis and bleeding risks.

The utility model provides a kind of net basket stone extraction device with biliary tract flushing function, including catheter, fixed ring, guide wire, flush pipe, pipeline guide silk;Wherein, catheter is equipped with first lead-through cavity, and multiple second lead-through cavities;First through-hole is set in fixed ring middle part;Guide wire is worn in second lead-through cavity, and front end forms net basket;Flush pipe is installed in first lead-through cavity, with infusion cavity;Pipeline guide silk is worn in the infusion cavity of flush pipe. When using, the front end of catheter is sent to calculus place through endoscope;Physiological saline is injected in flush pipe, and calculus periphery adherend is washed;Then flush pipe is extracted, then guide wire is pushed to make net basket open and cover calculus, and is withdrawn with endoscope;After calculus is extracted, flush pipe is installed by pipeline guide silk, and is entered again to flush biliary tract and remove residue. The device reduces operation time and complexity, avoids multiple instruments cross into human body, and reduces biliary tract injury and bleeding risk.